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Journal Articles

Abstract 5844: Landscapes of acquired EGFR and VEGF resistance alterations in colorectal cancer: findings from the PARADIGM biomarker study

Cancer Res (2024) 84 (6_Supplement): 5844.

https://doi.org/10.1158/1538-7445.AM2024-5844

Published: 22 March 2024

View articletitled, Abstract 5844: Landscapes of acquired EGFR and VEGF resistance alterations in colorectal cancer: findings from the PARADIGM biomarker study

Journal Articles

Abstract 3225: Real-world surveillance from cancer patients about their experience of comprehensive genomic profiling tests in Japan

Cancer Res (2023) 83 (7_Supplement): 3225.

https://doi.org/10.1158/1538-7445.AM2023-3225

Published: 04 April 2023

View articletitled, Abstract 3225: Real-world surveillance from cancer patients about their experience of comprehensive genomic profiling tests in Japan

Journal Articles

Single-Cell Analyses Reveal Diverse Mechanisms of Resistance to EGFR Tyrosine Kinase Inhibitors in Lung Cancer

Yukie Kashima, Daisuke Shibahara, Ayako Suzuki, Kyoko Muto, Ikei S. Kobayashi, David Plotnick, Hibiki Udagawa, Hiroki Izumi, Yuji Shibata, Kosuke Tanaka, Masanori Fujii, Akihiro Ohashi, Masahide Seki, Koichi Goto, Katsuya Tsuchihara, Yutaka Suzuki, Susumu S. Kobayashi

Cancer Res (2021) 81 (18): 4835–4848.

https://doi.org/10.1158/0008-5472.CAN-20-2811

Published: 15 September 2021

View articletitled, Single-Cell Analyses Reveal Diverse Mechanisms of Resistance to EGFR Tyrosine Kinase Inhibitors in Lung Cancer

Includes: Supplementary data

Journal Articles

Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung Cancer

Cancer Res (2021) 81 (14): 3916–3929.

https://doi.org/10.1158/0008-5472.CAN-20-4048

Published: 15 July 2021

View articletitled, Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung Cancer

Includes: Supplementary data

Journal Articles

Abstract 1974: Clonal and subclonal mutational landscapes in circulating tumor DNA in metastatic colorectal cancer: An exploratory analysis from the phase III PARADIGM study

Cancer Res (2020) 80 (16_Supplement): 1974.

https://doi.org/10.1158/1538-7445.AM2020-1974

Published: 15 August 2020

View articletitled, Abstract 1974: Clonal and subclonal mutational landscapes in circulating tumor DNA in metastatic colorectal cancer: An exploratory analysis from the phase III PARADIGM study

Journal Articles

Abstract 5026: The association of genomic features and immunosuppression in gastric cancer

Shogo Kumagai, Yosuke Togashi, Kohei Shitara, Takahiro Kinoshita, Katsuya Tsuchihara, Hiroyoshi Nishikawa

Cancer Res (2019) 79 (13_Supplement): 5026.

https://doi.org/10.1158/1538-7445.AM2019-5026

Published: 01 July 2019

View articletitled, Abstract 5026: The association of genomic features and immunosuppression in gastric cancer

Journal Articles

Abstract 3932: Metabolic biomarkers predict the sensitivity to phosphatidylinositol 3-kinase pathway inhibitor in small-cell lung carcinoma

Shigeki Umemura, Hideki Makinoshima, Genichiro Ishii, Takehiko Sasaki, Hiroyasu Esumi, Koichi Goto, Katsuya Tsuchihara

Cancer Res (2018) 78 (13_Supplement): 3932.

https://doi.org/10.1158/1538-7445.AM2018-3932

Published: 01 July 2018

View articletitled, Abstract 3932: Metabolic biomarkers predict the sensitivity to phosphatidylinositol 3-kinase pathway inhibitor in small-cell lung carcinoma

Journal Articles

Abstract 918: A secondary RET mutation allosterically conferring resistance to vandetanib

Takashi Nakaoku, Takashi Kohno, Mitsugu Araki, Seiji Nino, Rakhee Chauhan, Phillip P. Knowles, Katsuya Tsuchihara, Shingo Matsumoto, Yoko Shimada, Sachiyo Mimaki, Genichiro Ishii, Hitoshi Ichikawa, Yasushi Okuno, Kiyotaka Yoh, Neil Q. McDonald, Koichi Goto

Cancer Res (2018) 78 (13_Supplement): 918.

https://doi.org/10.1158/1538-7445.AM2018-918

Published: 01 July 2018

View articletitled, Abstract 918: A secondary RET mutation allosterically conferring resistance to vandetanib

Journal Articles

Abstract CT164: Circulating tumor DNA analysis for predictive and prognostic factors in patients with metastatic colorectal cancer: An exploratory analysis from the phase III PARADIGM study

Cancer Res (2018) 78 (13_Supplement): CT164.

https://doi.org/10.1158/1538-7445.AM2018-CT164

Published: 01 July 2018

View articletitled, Abstract CT164: Circulating tumor DNA analysis for predictive and prognostic factors in patients with metastatic colorectal cancer: An exploratory analysis from the phase III PARADIGM study

Journal Articles

Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma

Hideki Makinoshima, Shigeki Umemura, Ayako Suzuki, Hiroki Nakanishi, Ami Maruyama, Hibiki Udagawa, Sachiyo Mimaki, Shingo Matsumoto, Seiji Niho, Genichiro Ishii, Masahiro Tsuboi, Atsushi Ochiai, Hiroyasu Esumi, Takehiko Sasaki, Koichi Goto, Katsuya Tsuchihara

Cancer Res (2018) 78 (9): 2179–2190.

https://doi.org/10.1158/0008-5472.CAN-17-2109

Published: 30 April 2018

View articletitled, Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma

Includes: Supplementary data

Journal Articles

Abstract 4111: EGFR wild type allele amplification induces acquired resistance to mutation-specific EGFR tyrosine kinase inhibitors in non-small cell lung cancer cells

Keigo Kobayashi, Shigenari Nukaga, Hiroyuki Yasuda, Keita Masuzawa, Jyunko Hamamoto, Ichiro Kawada, Katsuhiko Naoki, Sachiyo Mimaki, Shingo Matsumoto, Koichi Goto, Katsuya Tsuchihara, Tomoko Betsuyaku, Kenzo Soejima

Cancer Res (2017) 77 (13_Supplement): 4111.

https://doi.org/10.1158/1538-7445.AM2017-4111

Published: 01 July 2017

View articletitled, Abstract 4111: EGFR wild type allele amplification induces acquired resistance to mutation-specific EGFR tyrosine kinase inhibitors in non-small cell lung cancer cells

Journal Articles

Amplification of EGFR Wild-Type Alleles in Non–Small Cell Lung Cancer Cells Confers Acquired Resistance to Mutation-Selective EGFR Tyrosine Kinase Inhibitors

Shigenari Nukaga, Hiroyuki Yasuda, Katsuya Tsuchihara, Junko Hamamoto, Keita Masuzawa, Ichiro Kawada, Katsuhiko Naoki, Shingo Matsumoto, Sachiyo Mimaki, Shinnosuke Ikemura, Koichi Goto, Tomoko Betsuyaku, Kenzo Soejima

Cancer Res (2017) 77 (8): 2078–2089.

https://doi.org/10.1158/0008-5472.CAN-16-2359

Published: 13 April 2017

View articletitled, Amplification of EGFR Wild-Type Alleles in Non–Small Cell Lung Cancer Cells Confers Acquired Resistance to Mutation-Selective EGFR Tyrosine Kinase Inhibitors

Includes: Supplementary data

Journal Articles

Abstract 5004: Expression profiling of receptor tyrosine kinases in high-grade neuroendocrine carcinoma of the lung: A comparative analysis with adenocarcinoma and squamous cell carcinoma

Yuki Matsumura, Shigeki Umemura, Genichiro Ishii, Koji Tsuta, Shingo Mastsumoto, Keiju Aokage, Tomoyuki Hishida, Junji Yoshida, Yuichiro Ohe, Hiroyuki Suzuki, Atsushi Ochiai, Koichi Goto, Kanji Nagai, Katsuya Tsuchihara

Cancer Res (2015) 75 (15_Supplement): 5004.

https://doi.org/10.1158/1538-7445.AM2015-5004

Published: 01 August 2015

View articletitled, Abstract 5004: Expression profiling of receptor tyrosine kinases in high-grade neuroendocrine carcinoma of the lung: A comparative analysis with adenocarcinoma and squamous cell carcinoma

Journal Articles

Abstract 2208: Detection of somatic mutations and gene amplifications using amplicon sequencing with biopsy samples from patients with advanced gastric cancer

Wataru Okamoto, Takeshi Kuwata, Shingo Matsumoto, Yoichi Naito, Hideaki Takahashi, Kohei Shitara, Yasutoshi Kuboki, Hideaki Bando, Yoko Yamada, Izumi Miki, Takeharu Yamanaka, Atsushi Ohtsu, Atsushi Ochiai, Hiroyasu Esumi, Takayuki Yoshino, Katsuya Tsuchihara

Cancer Res (2014) 74 (19_Supplement): 2208.

https://doi.org/10.1158/1538-7445.AM2014-2208

Published: 01 October 2014

View articletitled, Abstract 2208: Detection of somatic mutations and gene amplifications using amplicon sequencing with biopsy samples from patients with advanced gastric cancer

Journal Articles

Abstract 3361: EGFR signaling regulates aerobic glycolysis in EGFR-mutated lung adenocarcinoma

Hideki Makinoshima, Masahiro Takita, Shingo Matsumoto, Atsushi Yagishita, Satoshi Owada, Hiroyasu Esumi, Katsuya Tsuchihara

Cancer Res (2014) 74 (19_Supplement): 3361.

https://doi.org/10.1158/1538-7445.AM2014-3361

Published: 01 October 2014

View articletitled, Abstract 3361: EGFR signaling regulates aerobic glycolysis in EGFR-mutated lung adenocarcinoma

Journal Articles

Abstract CT213: Arctigenin, an antiausterity agent shows high safety and promising clinical response in phase I clinical trial in patient with gemcitabine-refractory pancreatic cancer

Hiroyasu Esumi, Satoshi Owada, Rumi Fujioka, Katsuya Tsuchihara, Atsushi Ohtsu, Aihiro Sato, Masafumi Ikeda, Nobuo Mochizuki, Satoshi Kishino, Takanori Kawashima, Satoshi Yomoda

Cancer Res (2014) 74 (19_Supplement): CT213.

https://doi.org/10.1158/1538-7445.AM2014-CT213

Published: 01 October 2014

View articletitled, Abstract CT213: Arctigenin, an antiausterity agent shows high safety and promising clinical response in phase I clinical trial in patient with gemcitabine-refractory pancreatic cancer

Journal Articles

Abstract 1214: RET fusion gene: translation to the therapy of lung adenocarcinoma.

Takashi Kohno, Hitoshi Ichikawa, Koji Tsuta, Tatsuji Mizukami, Yoko Shimada, Mamoru Kato, Hiromi Sakamoto, Katsuya Tsuchihara, Shun-ichi Watanabe, Hiroshi Nokihara, Koichi Goto, Jun Yokota, Teruhiko Yoshida, Tatsuhiro Shibata

Cancer Res (2013) 73 (8_Supplement): 1214.

https://doi.org/10.1158/1538-7445.AM2013-1214

Published: 15 April 2013

View articletitled, Abstract 1214: RET fusion gene: translation to the therapy of lung adenocarcinoma.

Journal Articles

Abstract 5134: The identification and characterization of genetic variations in lung adenocarcinomas in a Japanese population

Sachiyo Mimaki, Ayako Suzuki, Koutatsu Matsushima, Makito Suzuki, Naomi Ogasawara, Yutaka Suzuki, Katsuya Tsuchihara, Hiroyasu Esumi

Cancer Res (2012) 72 (8_Supplement): 5134.

https://doi.org/10.1158/1538-7445.AM2012-5134

Published: 15 April 2012

View articletitled, Abstract 5134: The identification and characterization of genetic variations in lung adenocarcinomas in a Japanese population

Journal Articles

Abstract 1133: Glucose deprivation-induced intracellular reactive oxygen species activates the PI3K-AKT axis

Satoshi Owada, Yuko Shimoda, Katsuya Tsuchihara, Hiroyasu Esumi

Cancer Res (2012) 72 (8_Supplement): 1133.

https://doi.org/10.1158/1538-7445.AM2012-1133

Published: 15 April 2012

View articletitled, Abstract 1133: Glucose deprivation-induced intracellular reactive oxygen species activates the PI3K-AKT axis

Journal Articles

Abstract #3419: Reduced tumor susceptibility and improved metabolic disorders by voluntary exercise in Snark-deficient mice

Katsuya Tsuchihara, Rumi Fujioka, Hiroyasu Esumi

Cancer Res (2009) 69 (9_Supplement): 3419.

Published: 01 May 2009

View articletitled, Abstract #3419: Reduced tumor susceptibility and improved metabolic disorders by voluntary exercise in Snark-deficient mice

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Abstract 5844: Landscapes of acquired EGFR and VEGF resistance alterations in colorectal cancer: findings from the PARADIGM biomarker study

Abstract 3225: Real-world surveillance from cancer patients about their experience of comprehensive genomic profiling tests in Japan

Single-Cell Analyses Reveal Diverse Mechanisms of Resistance to EGFR Tyrosine Kinase Inhibitors in Lung Cancer

Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung Cancer

Abstract 1974: Clonal and subclonal mutational landscapes in circulating tumor DNA in metastatic colorectal cancer: An exploratory analysis from the phase III PARADIGM study

Abstract 5026: The association of genomic features and immunosuppression in gastric cancer

Abstract 3932: Metabolic biomarkers predict the sensitivity to phosphatidylinositol 3-kinase pathway inhibitor in small-cell lung carcinoma

Abstract 918: A secondary RET mutation allosterically conferring resistance to vandetanib

Abstract CT164: Circulating tumor DNA analysis for predictive and prognostic factors in patients with metastatic colorectal cancer: An exploratory analysis from the phase III PARADIGM study

Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma

Abstract 4111: EGFR wild type allele amplification induces acquired resistance to mutation-specific EGFR tyrosine kinase inhibitors in non-small cell lung cancer cells

Amplification of EGFR Wild-Type Alleles in Non–Small Cell Lung Cancer Cells Confers Acquired Resistance to Mutation-Selective EGFR Tyrosine Kinase Inhibitors

Abstract 5004: Expression profiling of receptor tyrosine kinases in high-grade neuroendocrine carcinoma of the lung: A comparative analysis with adenocarcinoma and squamous cell carcinoma

Abstract 2208: Detection of somatic mutations and gene amplifications using amplicon sequencing with biopsy samples from patients with advanced gastric cancer

Abstract 3361: EGFR signaling regulates aerobic glycolysis in EGFR-mutated lung adenocarcinoma

Abstract CT213: Arctigenin, an antiausterity agent shows high safety and promising clinical response in phase I clinical trial in patient with gemcitabine-refractory pancreatic cancer

Abstract 1214: RET fusion gene: translation to the therapy of lung adenocarcinoma.

Abstract 5134: The identification and characterization of genetic variations in lung adenocarcinomas in a Japanese population

Abstract 1133: Glucose deprivation-induced intracellular reactive oxygen species activates the PI3K-AKT axis

Abstract #3419: Reduced tumor susceptibility and improved metabolic disorders by voluntary exercise in Snark-deficient mice

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