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Kathy Q. Cai
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Journal Articles

Abstract 5268: Targeting DHX9 triggers interferon response and replication stress in small cell lung cancer

Free
Takahiko Murayama, Jun Nakayama, Kathy Q. Cai, Kenichi Miyata, Andrey Efimov, Yinfei Tan, Yan Zhou, Kerry S. Campbell, Yibin Yang, Siddharth Balachandran, Israel Cañadas
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5268.
https://doi.org/10.1158/1538-7445.AM2024-5268
Published: 22 March 2024
View articletitled, Abstract 5268: Targeting DHX9 triggers interferon response and replication stress in small cell lung cancer
Journal Articles

Abstract B019: Inflammatory response to dietary carbohydrates contributes to the formation of hepatic metastatic niche

Free
Aizhan Surumbayeva, Riley Williams, Michael Kotliar, Maryclare Taylor, Débora B. Vendramini Costa, Charline Ogier, Diana Restifo, Kathy Q. Cai, Xueyang He, Paul Boutz, Siddharth Balachandran, Igor Astsaturov
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): B019.
https://doi.org/10.1158/1538-7445.PANCA22-B019
Published: 15 November 2022
View articletitled, Abstract B019: Inflammatory response to dietary carbohydrates contributes to the formation of hepatic metastatic niche
Journal Articles

Abstract C047: Phospholipid scramblase TMEM16F in cancer associated fibroblasts regulates trogocytosis to sustain critical dependency of pancreatic cancer cells on exogenous lipids

Free
Charline Ogier, Alena Klochkova, Linara Gabitova-Cornell, Battuya Bayarmagnai, Diana Restifo, Aizhan Surumbayeva, Debora Barbosa Vendramini-Costa, Ralph Francescone, Janusz Franco-Barraza, Jaye Gardiner, Emmanuelle Nicolas, Andrei Efimov, Elizabeth A. Handorf, Kathy Q. Cai, Bojana Gligorijevic, Edna Cukierman, Igor Astsaturov
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): C047.
https://doi.org/10.1158/1538-7445.PANCA22-C047
Published: 15 November 2022
View articletitled, Abstract C047: Phospholipid scramblase TMEM16F in cancer associated fibroblasts regulates trogocytosis to sustain critical dependency of pancreatic cancer cells on exogenous lipids
Journal Articles

Abstract 1571: Cancer associated fibroblasts sustain critical dependency of pancreatic cancer cells on exogenous lipids

Free
Charline Ogier, Alena Klochkova, Battuya Bayarmagnai, Linara Gabitova, Diana Restifo, Aizhan Surumbayeva, Janusz Franco-Barraza, Debora Vendramini Costa, Ralph Francescone, Jaye Gardiner, Emmanuelle Nicolas, Elizabeth A. Handorf, Kathy Q. Cai, Edna Cukierman, Igor Astsaturov
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1571.
https://doi.org/10.1158/1538-7445.AM2022-1571
Published: 15 June 2022
View articletitled, Abstract 1571: Cancer associated fibroblasts sustain critical dependency of pancreatic cancer cells on exogenous lipids
Journal Articles

Abstract 816: Cyclin c suppresses pancreatic intraepithelial neoplasm progression and neuroendocrine neoplasm development in a murine Kras model

Free
Kathy Q. Cai, Sara E. Hanley, Andres Klein-Szanto, Kerry S. Campbell, Randy Strich
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 816.
https://doi.org/10.1158/1538-7445.AM2022-816
Published: 15 June 2022
View articletitled, Abstract 816: Cyclin c suppresses pancreatic intraepithelial neoplasm progression and neuroendocrine neoplasm development in a murine Kras model
Journal Articles

Abstract 3649: Stromal netrinG1-ligand (NGL1) constitutes a new modulator of pancreatic cancer immunosuppression

Free
Débora B. Vendramini-Costa, Ralph Francescone, Janusz Franco-Barraza, Tiffany Luong, Esteban Martinez, Stephen Sykes, Nina G. Steele, Benjamin L. Allen, Marina Pasca di Magliano, Dmitry I. Zhigarev, Charline Ogier, Igor Astsaturov, Kathy Q. Cai, Andres J. Klein-Szanto, Huamin Wang, Kerry Campbell, Edna Cukierman
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3649.
https://doi.org/10.1158/1538-7445.AM2022-3649
Published: 15 June 2022
View articletitled, Abstract 3649: Stromal netrinG1-ligand (NGL1) constitutes a new modulator of pancreatic cancer immunosuppression
Journal Articles

Abstract P1-24-02: Genetic variants and tumor microenvironment in inflammatory breast cancer: Clues for targeted therapies

Free
Maria F. Arisi, Yulan Gong, Rajeswari Nagarathinam, Lorenzo Gerratana, Jianming Pei, Kathy Q. Cai, Jennifer Winn, Zachary Hasse, Elias Obeid, Julio Noriega, Christopher Sebastiano, Eric Ross, R. Katherine Alpaugh, Massimo Cristofanilli, Sandra V Fernandez
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-24-02.
https://doi.org/10.1158/1538-7445.SABCS21-P1-24-02
Published: 15 February 2022
View articletitled, Abstract P1-24-02: Genetic variants and tumor microenvironment in inflammatory breast cancer: Clues for targeted therapies
Journal Articles

Abstract PR-015: Cancer-associated fibroblasts sustain critical dependency of pancreatic cancer cells on exogenous lipids

Free
Charline Ogier, Alena Klochkova, Linara Gabitova, Battuya Bayarmagnai, Diana Restifo, Aizhan Surumbayeva, Janusz Franco-Barraza, Ralph Francescone, Debora B. Barbosa Vendramini-Costa, Jaye Gardiner, Emmanuelle Nicolas, Elizabeth A. Handorf, Kathy Q. Cai, Edna Cukierman, Igor Astsaturov
Journal: Cancer Research
Cancer Res (2021) 81 (22_Supplement): PR-015.
https://doi.org/10.1158/1538-7445.PANCA21-PR-015
Published: 15 November 2021
View articletitled, Abstract PR-015: Cancer-associated fibroblasts sustain critical dependency of pancreatic cancer cells on exogenous lipids
Journal Articles

Abstract PO-096: The synaptic protein Netrin G1 ligand (NGL-1) modulates tumorigenesis and immunosuppression in pancreatic cancer

Free
Debora Barbosa Vendramini Costa, Ralph Francescone, Janusz Franco-Barraza, Tiffany Luong, Nina Steele, Benjamin Allen, Marina Pasca di Magliano, Charline Ogier, Igor Astsaturov, Kathy Q. Cai, Andres J. Klein-Szanto, Huamin Wang, Kerry Campbell, Edna Cukierman
Journal: Cancer Research
Cancer Res (2021) 81 (22_Supplement): PO-096.
https://doi.org/10.1158/1538-7445.PANCA21-PO-096
Published: 15 November 2021
View articletitled, Abstract PO-096: The synaptic protein Netrin G1 ligand (NGL-1) modulates tumorigenesis and immunosuppression in pancreatic cancer
Journal Articles

Abstract PO-068: Cholesterol auxotrophy promotes the expansion of centroacinar cells giving rise to the basal subtype of pancreatic adenocarcinoma

Free
Michael Kotliar, Aizhan Surumbayeva, Linara Gabitova, Suraj Peri, Diana Restifo, Kathy Q. Cai, Artem Barski, Igor Astsaturov
Journal: Cancer Research
Cancer Res (2021) 81 (22_Supplement): PO-068.
https://doi.org/10.1158/1538-7445.PANCA21-PO-068
Published: 15 November 2021
View articletitled, Abstract PO-068: Cholesterol auxotrophy promotes the expansion of centroacinar cells giving rise to the basal subtype of pancreatic adenocarcinoma
Journal Articles

Abstract 116: Stromal expression of the synaptic protein netrin G1 ligand (NGL-1) promotes tumorigenesis and immunosuppression in pancreatic cancer

Free
Debora B. Vendramini-Costa, Ralph Francescone, Tiffany Luong, Janusz Franco-Barraza, Igor Astsaturov, Kathy Q. Cai, Andres J. Klein-Szanto, Huamin Wang, Kerry S. Campbell, Edna Cukierman
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 116.
https://doi.org/10.1158/1538-7445.AM2021-116
Published: 01 July 2021
View articletitled, Abstract 116: Stromal expression of the synaptic protein netrin G1 ligand (NGL-1) promotes tumorigenesis and immunosuppression in pancreatic cancer
Journal Articles

Abstract LT019: The synaptic protein netrin G1 ligand (NGL-1) modulates the immunosuppressive environment in pancreatic cancer

Free
Debora Barbosa Vendramini-Costa, Ralph Francescone, Tiffany Luong, Janusz Franco-Barraza, Igor Astsaturov, Kathy Q. Cai, Andres J. Klein-Szanto, Huamin Wang, Kerry Campbell, Edna Cukierman
Journal: Cancer Research
Cancer Res (2021) 81 (5_Supplement): LT019.
https://doi.org/10.1158/1538-7445.TME21-LT019
Published: 01 March 2021
View articletitled, Abstract LT019: The synaptic protein netrin G1 ligand (NGL-1) modulates the immunosuppressive environment in pancreatic cancer
Journal Articles

RNF168-Mediated Ubiquitin Signaling Inhibits the Viability of BRCA1-Null Cancers

Free
John J. Krais, Yifan Wang, Andrea J. Bernhardy, Emma Clausen, Jessica A. Miller, Kathy Q. Cai, Clare L. Scott, Neil Johnson
Journal: Cancer Research
Cancer Res (2020) 80 (13): 2848–2860.
https://doi.org/10.1158/0008-5472.CAN-19-3033
Published: 02 July 2020
View articletitled, RNF168-Mediated Ubiquitin Signaling Inhibits the Viability of BRCA1-Null Cancers
Open the PDF for RNF168-Mediated Ubiquitin Signaling Inhibits the Viability of BRCA1-Null Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract C06: Cholesterol deprivation induces TGFβ signaling to promote basal differentiation in pancreatic cancer

Free
Linara Gabitova, Suraj Peri, Ralph Francescone, Janusz Franco-Barraza, Neelima Shah, Emmanuelle Nicolas, Elizabeth A. Handorf, Kathy Q. Cai, Ido Sloma, Rachel Chiaverelli, Richard Moffitt, Erica A. Golemis, Carolyn Fang, Shannon Lynch, Edna Cukierman, Igor Astsaturov
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): C06.
https://doi.org/10.1158/1538-7445.PANCA19-C06
Published: 13 December 2019
View articletitled, Abstract C06: Cholesterol deprivation induces TGFβ signaling to promote basal differentiation in pancreatic cancer
Journal Articles

Inactivation of Bap1 Cooperates with Losses of Nf2 and Cdkn2a to Drive the Development of Pleural Malignant Mesothelioma in Conditional Mouse Models

Free
Anna-Mariya Kukuyan, Eleonora Sementino, Yuwaraj Kadariya, Craig W. Menges, Mitchell Cheung, Yinfei Tan, Kathy Q. Cai, Michael J. Slifker, Suraj Peri, Andres J. Klein-Szanto, Frank J. Rauscher, III, Joseph R. Testa
Journal: Cancer Research
Cancer Res (2019) 79 (16): 4113–4123.
https://doi.org/10.1158/0008-5472.CAN-18-4093
Published: 15 August 2019
View articletitled, Inactivation of Bap1 Cooperates with Losses of Nf2 and Cdkn2a to Drive the Development of Pleural Malignant Mesothelioma in Conditional Mouse Models
Open the PDF for Inactivation of Bap1 Cooperates with Losses of Nf2 and Cdkn2a to Drive the Development of Pleural Malignant Mesothelioma in Conditional Mouse Models in another window
Includes: Supplementary data
Journal Articles

Abstract 2038: NG1/NGL1 engagement supports PDAC development via CAF to PDAC nutrition and CAF-regulated immunosuppression

Free
Ralph Francescone, Débora Barbosa Vendramini-Costa, Janusz Franco-Barraza, Jessica Wagner, Alex Muir, Linara Gabitova, Tatiana Pazina, Tiffany Luong, Neelima Shah, Dustin Rollins, Ruchi Malik, Sapna Gupta, Roshan Thapa, Diana Restifo, Allison Lau, Yan Zhou, Kathy Q. Cai, Harvey Harvey Hensley, Emmanuelle Nicolas, Warren D. Kruger, Karthik Devarajan, Siddharth Balachandran, Wafik S. El-Deiry, Matthew Vander Heiden, Kerry Campbell, Igor Astsaturov, Edna Cukierman
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2038.
https://doi.org/10.1158/1538-7445.AM2019-2038
Published: 01 July 2019
View articletitled, Abstract 2038: NG1/NGL1 engagement supports PDAC development via CAF to PDAC nutrition and CAF-regulated immunosuppression
Journal Articles

Specific Targeting of MTAP-Deleted Tumors with a Combination of 2′-Fluoroadenine and 5′-Methylthioadenosine

Free
Baiqing Tang, Hyung-Ok Lee, Serim S. An, Kathy Q. Cai, Warren D. Kruger
Journal: Cancer Research
Cancer Res (2018) 78 (15): 4386–4395.
https://doi.org/10.1158/0008-5472.CAN-18-0814
Published: 31 July 2018
View articletitled, Specific Targeting of MTAP-Deleted Tumors with a Combination of 2′-Fluoroadenine and 5′-Methylthioadenosine
Open the PDF for Specific Targeting of MTAP-Deleted Tumors with a Combination of 2′-Fluoroadenine and 5′-Methylthioadenosine in another window
Includes: Supplementary data
Journal Articles

Abstract 4452: Musashi-2 regulates EGFR/HER3 expression in NSCLC, cell proliferation and response to EGFR inhibitors in EGFR-mutant NSCLC

Free
Peter Makhov, Alexander Kudinov, Alexander Deneka, Brian L. Egleston, Emmanuelle Nicolas, Kathy Q. Cai, Rohan Brebion, Eleanor Avril, Mark Hitrik, Anna S. Nikonova, Ilya G. Serebriiskii, Vladimir Khazak, Hossein Borghaei, Erica A. Golemis, Yanis Boumber
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4452.
https://doi.org/10.1158/1538-7445.AM2018-4452
Published: 01 July 2018
View articletitled, Abstract 4452: Musashi-2 regulates EGFR/HER3 expression in NSCLC, cell proliferation and response to EGFR inhibitors in EGFR-mutant NSCLC
Journal Articles

Abstract 26: Sensitive step in cholesterol biosynthesis reveals role for sterol metabolites in regulating growth of EGFR/KRAS-dependent tumors

Free
Linara Gabitova, Diana Restifo, Elizabeth Handorf, Kathy Q. Cai, Igor A. Astsaturov
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 26.
https://doi.org/10.1158/1538-7445.AM2016-26
Published: 15 July 2016
View articletitled, Abstract 26: Sensitive step in cholesterol biosynthesis reveals role for sterol metabolites in regulating growth of EGFR/KRAS-dependent tumors
Journal Articles

Ribosomal Protein Rpl22 Controls the Dissemination of T-cell Lymphoma

Free
Shuyun Rao, Kathy Q. Cai, Jason E. Stadanlick, Noa Greenberg-Kushnir, Nehal Solanki-Patel, Sang-Yun Lee, Shawn P. Fahl, Joseph R. Testa, David L. Wiest
Journal: Cancer Research
Cancer Res (2016) 76 (11): 3387–3396.
https://doi.org/10.1158/0008-5472.CAN-15-2698
Published: 31 May 2016
View articletitled, Ribosomal Protein Rpl22 Controls the Dissemination of T-cell Lymphoma
Open the PDF for Ribosomal Protein Rpl22 Controls the Dissemination of T-cell Lymphoma in another window
Includes: Supplementary data