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Kathleen C. Flanders
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Journal Articles

Abstract 2244: Functional interactions between estrogen-related-receptor β (ESRRB) and transforming growth factor-beta (TGF-β) in the regulation of breast cancer stem cell dynamics

Nellie Moshkovich, Misako Sato, Binwu Tang, Yu-an Yang, Kathleen C. Flanders, Mitsutaka Kadota, Howard Yang, Maxwell P. Lee, Lalage M. Wakefield
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2244.
https://doi.org/10.1158/1538-7445.AM2015-2244
Published: 01 August 2015
View article titled, Abstract 2244: Functional interactions between estrogen-related-receptor β (ESRRB) and transforming growth factor-beta (TGF-β) in the regulation of breast cancer stem cell dynamics
Journal Articles

Abstract 4094: Neutralizing anti-TGF-β antibodies elicit heterogeneous therapeutic responses in a panel of murine metastatic breast cancer models

Yu-an Yang, Kathleen C. Flanders, Binwu Tang, Miriam R. Anver, Anand Merchant, Howard Yang, Maxwell Lee, Scott Lonning, John M. McPherson, Lalage M. Wakefield
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4094.
https://doi.org/10.1158/1538-7445.AM2015-4094
Published: 01 August 2015
View article titled, Abstract 4094: Neutralizing anti-TGF-β antibodies elicit heterogeneous therapeutic responses in a panel of murine metastatic breast cancer models
Journal Articles

Abstract 2221: Transforming Growth Factor-beta (TGF-β) directly regulates breast cancer stem cell dynamics in vitro and in vivo

Binwu Tang, Asaf Raviv, Dominic Esposito, Catherine Daniel, Kathleen C. Flanders, Yu-an Yang, Lalage M. Wakefield
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2221.
https://doi.org/10.1158/1538-7445.AM2015-2221
Published: 01 August 2015
View article titled, Abstract 2221: Transforming Growth Factor-beta (TGF-β) directly regulates breast cancer stem cell dynamics in vitro and in vivo
Journal Articles

Definition of Smad3 Phosphorylation Events That Affect Malignant and Metastatic Behaviors in Breast Cancer Cells

Eunjin Bae, Misako Sato, Ran-Ju Kim, Mi-Kyung Kwak, Kazuhito Naka, Jungsoo Gim, Mitsutaka Kadota, Binwu Tang, Kathleen C. Flanders, Tae-Aug Kim, Sun-Hee Leem, Taesung Park, Fang Liu, Lalage M. Wakefield, Seong-Jin Kim, Akira Ooshima
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (21): 6139–6149.
https://doi.org/10.1158/0008-5472.CAN-14-0803
Published: 30 October 2014
View article titled, Definition of Smad3 Phosphorylation Events That Affect Malignant and Metastatic Behaviors in Breast Cancer Cells
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Includes: Supplementary data
Journal Articles

Progressive Tumor Formation in Mice with Conditional Deletion of TGF-β Signaling in Head and Neck Epithelia Is Associated with Activation of the PI3K/Akt Pathway

Yansong Bian, Anita Terse, Juan Du, Bradford Hall, Alfredo Molinolo, Pin Zhang, Wanjun Chen, Kathleen C. Flanders, J. Silvio Gutkind, Lalage M. Wakefield, Ashok B. Kulkarni
Journal: Cancer Research
Cancer Res (2009) 69 (14): 5918–5926.
https://doi.org/10.1158/0008-5472.CAN-08-4623
Published: 15 July 2009
View article titled, Progressive Tumor Formation in Mice with Conditional Deletion of TGF-β Signaling in Head and Neck Epithelia Is Associated with Activation of the PI3K/Akt Pathway
Open the PDF for Progressive Tumor Formation in Mice with Conditional Deletion of TGF-β Signaling in Head and Neck Epithelia Is Associated with Activation of the PI3K/Akt Pathway in another window
Includes: Supplementary data
Journal Articles

A Novel Synthetic Oleanane Triterpenoid, 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic Acid, with Potent Differentiating, Antiproliferative, and Anti-Inflammatory Activity

Nanjoo Suh, Yongping Wang, Tadashi Honda, Gordon W. Gribble, Ethan Dmitrovsky, William F. Hickey, Robert A. Maue, Andrew E. Place, Donna M. Porter, Michael J. Spinella, Charlotte R. Williams, Gengfei Wu, Andrew J. Dannenberg, Kathleen C. Flanders, John J. Letterio, David J. Mangelsdorf, Carl F. Nathan, Lananh Nguyen, Weston W. Porter, Renee F. Ren, Anita B. Roberts, Nanette S. Roche, Kotha Subbaramaiah, Michael B. Sporn
Journal: Cancer Research
Cancer Res (1999) 59 (2): 336–341.
Published: 15 January 1999
View article titled, A Novel Synthetic Oleanane Triterpenoid, 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic Acid, with Potent Differentiating, Antiproliferative, and Anti-Inflammatory Activity
Open the PDF for A Novel Synthetic Oleanane Triterpenoid, 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic Acid, with Potent Differentiating, Antiproliferative, and Anti-Inflammatory Activity in another window
Journal Articles

Deficient Transforming Growth Factor-β1 Activation and Excessive Insulin-like Growth Factor II (IGFII) Expression in IGFII Receptor-Mutant Tumors

Suna Wang, Rhonda F. Souza, Dehe Kong, Jing Yin, Kara N. Smolinski, Tong-Tong Zou, Tom Frank, Joanne Young, Kathleen C. Flanders, Haruhiko Sugimura, John M. Abraham, Stephen J. Meltzer
Journal: Cancer Research
Cancer Res (1997) 57 (13): 2543–2546.
Published: 01 July 1997
View article titled, Deficient Transforming Growth Factor-β1 Activation and Excessive Insulin-like Growth Factor II (IGFII) Expression in IGFII Receptor-Mutant Tumors
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Journal Articles

Transforming Growth Factor β1 Induction Is Associated with Transforming Growth Factors β2 and β3 Down-Modulation in 12-O-Tetradecanoylphorbol-13-acetate-induced Skin Hyperplasia

Joseph S. Esherick, Ferdinando DiCunto, Kathleen C. Flanders, Caterina Missero, G. Paolo Dotto
Journal: Cancer Research
Cancer Res (1993) 53 (22): 5517–5522.
Published: 01 November 1993
View article titled, Transforming Growth Factor β<sub>1</sub> Induction Is Associated with Transforming Growth Factors β<sub>2</sub> and β<sub>3</sub> Down-Modulation in 12-<em>O</em>-Tetradecanoylphorbol-13-acetate-induced Skin Hyperplasia
Open the PDF for Transforming Growth Factor β<sub>1</sub> Induction Is Associated with Transforming Growth Factors β<sub>2</sub> and β<sub>3</sub> Down-Modulation in 12-<em>O</em>-Tetradecanoylphorbol-13-acetate-induced Skin Hyperplasia in another window
Journal Articles

Induction of Transforming Growth Factor β1 in Human Breast Cancer in Vivo following Tamoxifen Treatment

Anju Butta, Kenneth MacLennan, Kathleen C. Flanders, Nigel P. M. Sacks, Ian Smith, Alan McKinna, Mitchell Dowsett, Lalage M. Wakefield, Michael B. Sporn, Michael Baum, Anthony A. Colletta
Journal: Cancer Research
Cancer Res (1992) 52 (15): 4261–4264.
Published: 01 August 1992
View article titled, Induction of Transforming Growth Factor β<sub>1</sub> in Human Breast Cancer <em>in Vivo</em> following Tamoxifen Treatment
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