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Katherine L. Cook
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Journal Articles

Abstract PO5-14-01: Weight loss and omega-3 polyunsaturated fatty acid intervention in overweight and obese peri- and postmenopausal women with increased breast cancer risk modifies the gut microbiome and is associated with circulating biomarkers

Katherine L. Cook, Erin Giles, Amy Kreutzjans, Shahid Umar, Christie Befort, Bruce Kimler, Stephen Hursting, Carol Fabian
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO5-14-01.
https://doi.org/10.1158/1538-7445.SABCS23-PO5-14-01
Published: 02 May 2024
View article titled, Abstract PO5-14-01: Weight loss and omega-3 polyunsaturated fatty acid intervention in overweight and obese peri- and postmenopausal women with increased breast cancer risk modifies the gut microbiome and is associated with circulating biomarkers
Journal Articles

Abstract PO2-08-10: Effect of 6 months of bazedoxifene + conjugated estrogens on body composition and insulin resistance

Carol Fabian, Adrian Zelenchuk, Kandy Powers, Amy Kreutzjans, Krystal Pittman, Bill Hendry, Christy Altman, Erin Giles, Katherine L. Cook, Stephen Hursting, Bruce Kimler
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO2-08-10.
https://doi.org/10.1158/1538-7445.SABCS23-PO2-08-10
Published: 02 May 2024
View article titled, Abstract PO2-08-10: Effect of 6 months of bazedoxifene + conjugated estrogens on body composition and insulin resistance
Journal Articles

Abstract PS07-08: Bazedoxifene plus conjugated estrogen reduces mammary proliferation markers and improves adipocyte size, gut microbiome, and metabolic health: Findings from a preclinical model of obesity and breast cancer risk

Katherine L. Cook, Ramsey Jenshcke, Karen Corleto, Carol Fabian, Stephen Hursting, Bruce Kimler, Danilo Landrock, Erin Giles
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PS07-08.
https://doi.org/10.1158/1538-7445.SABCS23-PS07-08
Published: 02 May 2024
View article titled, Abstract PS07-08: Bazedoxifene plus conjugated estrogen reduces mammary proliferation markers and improves adipocyte size, gut microbiome, and metabolic health: Findings from a preclinical model of obesity and breast cancer risk
Journal Articles

Abstract 2181: Endocrine-targeting therapies modify the breast microbiome to shift metabolism and reduce cancer risk

Alana Arnone, Yu-Ting Tsai, J Mark Cline, Adam S. Wilson, Brian Westwood, Meghan E. Seger, Akiko Chiba, Marissa Howard-McNatt, Edward A. Levine, Alexandra Thomas, David R. Soto-Pantoja, Katherine L. Cook
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2181.
https://doi.org/10.1158/1538-7445.AM2024-2181
Published: 22 March 2024
View article titled, Abstract 2181: Endocrine-targeting therapies modify the breast microbiome to shift metabolism and reduce cancer risk
Journal Articles

Abstract 1423: Harnessing the gut microbiome to modulate immune checkpoint blockade response in triple-negative breast cancer

Kenysha YJ. Clear, Adam S. Wilson, Elizabeth R. Stirling, Yu-Ting Tsai, Valerie Payne, David R. Soto-Pantoja, Katherine L. Cook
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1423.
https://doi.org/10.1158/1538-7445.AM2024-1423
Published: 22 March 2024
View article titled, Abstract 1423: Harnessing the gut microbiome to modulate immune checkpoint blockade response in triple-negative breast cancer
Journal Articles

Abstract 2179: Microbiome-derived metabolites mediate carcinogenic alterations of breast tissue in the context of obesity

Mohamed Gaber, Kayla Neary, Julia Holmes, Adam S. Wilson, Adam J. Katz, Pierre-Alexandre Vidi, Katherine L. Cook
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2179.
https://doi.org/10.1158/1538-7445.AM2024-2179
Published: 22 March 2024
View article titled, Abstract 2179: Microbiome-derived metabolites mediate carcinogenic alterations of breast tissue in the context of obesity
Journal Articles

Abstract 3030: Effect of 6 months of bazedoxifene and conjugated estrogen on measures of insulin resistance in postmenopausal women at increased risk for breast cancer

Carol J. Fabian, Erin D. Giles, Katherine L. Cook, Kandy Powers, Christy Altman, Amy Kreutzjans, Teresa Phillips, Adrian Zelenchuk, Krystal Pittman, Stephen D. Hursting, Bruce Kimler
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3030.
https://doi.org/10.1158/1538-7445.AM2023-3030
Published: 04 April 2023
View article titled, Abstract 3030: Effect of 6 months of bazedoxifene and conjugated estrogen on measures of insulin resistance in postmenopausal women at increased risk for breast cancer
Journal Articles

Abstract 5259: Bazedoxifene plus conjugated estrogen improves metabolic health and reduces mammary gland epithelial proliferation in an ovary intact rat model of obesity and breast cancer risk

Ramsey M. Jenschke, Karen A. Corleto, Carol J. Fabian, Stephen D. Hursting, Bruce F. Kimler, Danilo Landrock, Tara N. Mahmood, Katherine L. Cook, Erin D. Giles
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5259.
https://doi.org/10.1158/1538-7445.AM2023-5259
Published: 04 April 2023
View article titled, Abstract 5259: Bazedoxifene plus conjugated estrogen improves metabolic health and reduces mammary gland epithelial proliferation in an ovary intact rat model of obesity and breast cancer risk
Journal Articles

Abstract P1-02-05: Endocrine-targeted therapies modify the gut microbiome affecting responsiveness in ER+ breast cancer

Alana Arnone, Adam S. Wilson, Akiko Chiba, Bethany Kerr, David R. Soto-Pantoja, Alexandra Thomas, Katherine L. Cook
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P1-02-05.
https://doi.org/10.1158/1538-7445.SABCS22-P1-02-05
Published: 01 March 2023
View article titled, Abstract P1-02-05: Endocrine-targeted therapies modify the gut microbiome affecting responsiveness in ER+ breast cancer
Journal Articles

Abstract P5-08-14: Blockade of CD47/Thrombospondin-1 signaling increases glycolytic metabolism as a protective mechanism against chemotherapy-associated cardiac injury in a model of Triple-Negative Breast Cancer

Steven M. Bronson, Jessica D. Mackert, Mitra Kooshki, Adam S. Wilson, Nildris Cruz-Diaz, Pierre L Triozzi, Alexandra Thomas, Katherine L. Cook, David R. Soto-Pantoja
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P5-08-14.
https://doi.org/10.1158/1538-7445.SABCS22-P5-08-14
Published: 01 March 2023
View article titled, Abstract P5-08-14: Blockade of CD47/Thrombospondin-1 signaling increases glycolytic metabolism as a protective mechanism against chemotherapy-associated cardiac injury in a model of Triple-Negative Breast Cancer
Journal Articles

Abstract P1-09-03: Omega-3 polyunsaturated fatty acid supplementation shifts the gut and breast microbiome to influence inflammation

Katherine L. Cook, Adam S Wilson, David R Soto-Pantoja, Bruce F. Kimler, Shahid Umar, Carol J. Fabian
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-09-03.
https://doi.org/10.1158/1538-7445.SABCS21-P1-09-03
Published: 15 February 2022
View article titled, Abstract P1-09-03: Omega-3 polyunsaturated fatty acid supplementation shifts the gut and breast microbiome to influence inflammation
Journal Articles

Diet Alters Entero-Mammary Signaling to Regulate the Breast Microbiome and Tumorigenesis

David R. Soto-Pantoja, Mohamed Gaber, Alana A. Arnone, Steven M. Bronson, Nildris Cruz-Diaz, Adam S. Wilson, Kenysha Y.J. Clear, Manuel U. Ramirez, Gregory L. Kucera, Edward A. Levine, Sophie A. Lelièvre, Lesley Chaboub, Akiko Chiba, Hariom Yadav, Pierre-Alexandre Vidi, Katherine L. Cook
Journal: Cancer Research
Cancer Res (2021) 81 (14): 3890–3904.
https://doi.org/10.1158/0008-5472.CAN-20-2983
Published: 15 July 2021
View article titled, Diet Alters Entero-Mammary Signaling to Regulate the Breast Microbiome and Tumorigenesis
Open the PDF for Diet Alters Entero-Mammary Signaling to Regulate the Breast Microbiome and Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

Abstract PS6-59: Impact of Cholecystectomy in Breast Cancer Recurrence

Isheeta Madeka, Rohin Gawdi, Katherine L Cook, Akiko Chiba
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS6-59.
https://doi.org/10.1158/1538-7445.SABCS20-PS6-59
Published: 15 February 2021
View article titled, Abstract PS6-59: Impact of Cholecystectomy in Breast Cancer Recurrence
Journal Articles

Abstract B15: Gut microbiome populations modulate neoadjuvant chemotherapy responsiveness in preclinical triple-negative breast cancer murine model

Kenysha Clear, Adam Wilson, Akiko Chiba, Katherine L. Cook, Alaa Bawaneh
Journal: Cancer Research
Cancer Res (2020) 80 (8_Supplement): B15.
https://doi.org/10.1158/1538-7445.MVC2020-B15
Published: 15 April 2020
View article titled, Abstract B15: Gut microbiome populations modulate neoadjuvant chemotherapy responsiveness in preclinical triple-negative breast cancer murine model
Journal Articles

Abstract 650: Gut microbiota population may be used to predict chemotherapeutic responsiveness in triple negative breast cancer

Alaa Bawaneh, Adam S. Wilson, Kenysha YJ Clear, Akiko Chiba, Katherine L. Cook
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 650.
https://doi.org/10.1158/1538-7445.AM2019-650
Published: 01 July 2019
View article titled, Abstract 650: Gut microbiota population may be used to predict chemotherapeutic responsiveness in triple negative breast cancer
Journal Articles

Abstract 2835: Breast tumor microbiota populations are modulated by chemotherapy and may be indicative of outcome

Akiko Chiba, Alaa Bawaneh, Christine Velazquez, Edward Levine, Katherine L. Cook
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2835.
https://doi.org/10.1158/1538-7445.AM2019-2835
Published: 01 July 2019
View article titled, Abstract 2835: Breast tumor microbiota populations are modulated by chemotherapy and may be indicative of outcome
Journal Articles

Abstract 3528: Anti-CD47 immunotherapy regulates T cell metabolism and hypoxia in the tumor microenvironment

Yismelin R. Feliz-Mosquea, Elizabeth Stirling, Katherine L. Cook, Adam Wilson, Manish Bharadwaj, Anthony J. Molina, Liliya Yamaleyeva, Pierre L. Triozzi, David R. Soto-Pantoja
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3528.
https://doi.org/10.1158/1538-7445.AM2018-3528
Published: 01 July 2018
View article titled, Abstract 3528: Anti-CD47 immunotherapy regulates T cell metabolism and hypoxia in the tumor microenvironment
Journal Articles

Abstract 449: Targeting PKR-like endoplasmic reticulum kinase modulates metabolism to promote T-cell effector function and PD1 immunotherapy responsiveness

David R. Soto-Pantoja, Yismeilin R. Feliz-Mosquea, Kenysha YJ Clear, Adam S. Wilson, Katherine L. Cook
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 449.
https://doi.org/10.1158/1538-7445.AM2018-449
Published: 01 July 2018
View article titled, Abstract 449: Targeting PKR-like endoplasmic reticulum kinase modulates metabolism to promote T-cell effector function and PD1 immunotherapy responsiveness
Journal Articles

Abstract 1704: UPR signaling promotes T-cell dysfunction to prevent immune-mediated cancer cell killing and immune checkpoint therapy resistance

Yismeilin R. Feliz Mosquea, David R. Soto Pantoja, Adam Wilson, Pierre L. Triozzi, Katherine L. Cook
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1704.
https://doi.org/10.1158/1538-7445.AM2017-1704
Published: 01 July 2017
View article titled, Abstract 1704: UPR signaling promotes T-cell dysfunction to prevent immune-mediated cancer cell killing and immune checkpoint therapy resistance
Journal Articles

Abstract B47: Silver nanoparticles exhibit subtype specific cytotoxic and therapeutic effects in claudin low breast cancer in vitro and in vivo

Jessica L. Swanner, Iliana Tenvooren, Brian W. Bernish, Cale D. Fahrenholtz, Pierre A. Vidi, Katherine L. Cook, Ravi N. Singh
Journal: Cancer Research
Cancer Res (2017) 77 (2_Supplement): B47.
https://doi.org/10.1158/1538-7445.EPSO16-B47
Published: 16 January 2017
View article titled, Abstract B47: Silver nanoparticles exhibit subtype specific cytotoxic and therapeutic effects in claudin low breast cancer in vitro and in vivo