1-12 of 12
Karen TenDyke
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract 3269: Discovery and characterization of E7766, a novel macrocycle-bridged STING agonist with pan-genotypic and potent antitumor activity through intravesical and intratumoral administration

Kuan-Chun Huang, Atsushi Endo, Shannon McGrath, Dinesh Chandra, Jiayi Wu, Dae-Shik Kim, Diana Albu, Christy Ingersoll, Karen Tendyke, Kara Loiacono, Thomas Noland, David Verbel, Chi Zhang, Ming-Hong Hao, Mark Matijevic, Vaishali Dixit, Renee R. Hukkanen, Janna Hutz, John Wang, Frank Fang, Xingfeng Bao, Donna Kolber-Simonds, Muzaffar Akram, Nadeem Sarwar
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3269.
https://doi.org/10.1158/1538-7445.AM2019-3269
Published: 01 July 2019
View article titled, Abstract 3269: Discovery and characterization of E7766, a novel macrocycle-bridged STING agonist with pan-genotypic and potent antitumor activity through intravesical and intratumoral administration
Journal Articles

Abstract 4456: Discovery of E7766: A representative of a novel class of macrocycle-bridged STING agonists (MBSAs) with superior potency and pan-genotypic activity

Atsushi ENDO, Dae-Shik Kim, Kuan-Chun Huang, Ming-Hong Hao, Steven Mathieu, Hyeong-wook Choi, Utpal Majumder, Xiaojie Zhu, Yongchun Shen, Kristen Sanders, Thomas Noland, Dinesh Chandra, Yu Chen, Karen TenDyke, Kara Loiacono, Donna Kolber-Simonds, Rongrong Jiang, Vaishali Dixit, Janna Hutz, John Wang, Xingfeng Bao, Francis Fang, Nadeem Sarwar
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4456.
https://doi.org/10.1158/1538-7445.AM2019-4456
Published: 01 July 2019
View article titled, Abstract 4456: Discovery of E7766: A representative of a novel class of macrocycle-bridged STING agonists (MBSAs) with superior potency and pan-genotypic activity
Journal Articles

Abstract 3961: Role for neuropilin1 in mode of action of chlorotoxin

Donna Kolber-Simonds, Jiayi Wu, Utpal Majumder, Daniel Custar, Danyang Li, Hong Du, Maarten H. Postema, Thomas Noland, Andrew Hart, George Lai, Sean Eckley, Vaishali Dixit, Karen Tendyke, Kenichi Nomoto, Mary Woodall-Jappe, Sharon McGonigle
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3961.
https://doi.org/10.1158/1538-7445.AM2018-3961
Published: 01 July 2018
View article titled, Abstract 3961: Role for neuropilin1 in mode of action of chlorotoxin
Journal Articles

Abstract 3323: E7449, a potent inhibitor of PARP 1 and 2, is active in acute myeloid leukemia.

Sharon McGonigle, Zhihong Chen, Jiayi Wu, Donna Kolber-Simonds, Shannon McGrath, Karen TenDyke, Zichun Wang, Kenichi Nomoto
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3323.
https://doi.org/10.1158/1538-7445.AM2013-3323
Published: 15 April 2013
View article titled, Abstract 3323: E7449, a potent inhibitor of PARP 1 and 2, is active in acute myeloid leukemia.
Journal Articles

Abstract 4688: E7449: A novel PARP inhibitor enhances the efficacy of radiotherapy and chemotherapy and has potent single agent anticancer activity in BRCA-deficient tumors

Sharon McGonigle, Zhihong Chen, Jiayi Wu, Karen Ackermann, Karen Tendyke, George Moniz, Kenichi Nomoto
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4688.
https://doi.org/10.1158/1538-7445.AM2012-4688
Published: 15 April 2012
View article titled, Abstract 4688: E7449: A novel PARP inhibitor enhances the efficacy of radiotherapy and chemotherapy and has potent single agent anticancer activity in BRCA-deficient tumors
Journal Articles

Abstract #2704: Second generation eribulin analogs: Efficacy against multi-drug resistant tumors and brain tumors

Sridhar Narayan, Eric Carlson, Hongsheng Cheng, Krista Condon, Hong Du, Sean Eckley, Yimin Jiang, Vipul Kumar, Bryan Lewis, Philip Saxton, Bryan Schuck, Boris Seletsky, Karen Tendyke, Huiming Zhang, Wanjun Zheng, Bruce Littlefield, Murray Towle, Melvin Yu
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2704.
Published: 01 May 2009
View article titled, Abstract #2704: Second generation eribulin analogs: Efficacy against multi-drug resistant tumors and brain tumors
Journal Articles

Potent in vitro and in vivo anticancer activities of desmethyl, desamino (DMDA)-pateamine A, an analog of marine natural product pateamine A

Galina Kuznetsov, Qunli Xu, Karen TenDyke, Junke Liu, Murray Towle, Nanding Zhao, Joanne Marsh, Sergei Agoulnik, Natalie Twine, Lana Parent, Zhihong Chen, Yimin Jiang, Huiming Zhang, Hong Du, Roch Boivin, John (Yuan) Wang, Daniel Romo, Bruce Littlefield
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5702.
Published: 01 May 2008
View article titled, Potent <em>in vitro</em> and <em>in vivo</em> anticancer activities of desmethyl, desamino (DMDA)-pateamine A, an analog of marine natural product pateamine A
Journal Articles

Synthetic analogs of the marine natural product hemiasterlin: Optimization and discovery of E7974, a novel and potent antitumor agent

James J. Kowalczyk, Shawn E. R. Schiller, Mark Spyvee, Hu Yang, Boris M. Seletsky, Christina J. Shaffer, Veronique Marceau, Ye Yao, Galina Kuznetsov, Karen Tendyke, Diana Liu, Cheryl Rowell, Bruce A. Littlefield, Edward M. Suh
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 282.
Published: 01 May 2005
View article titled, Synthetic analogs of the marine natural product hemiasterlin: Optimization and discovery of E7974, a novel and potent antitumor agent
Journal Articles

In vitro and in vivo antitumor activities of novel hemiasterlin analog E7974

Galina Kuznetsov, Karen Tendyke, Murray J. Towle, Hongsheng Cheng, Diana Liu, Cheryl Rowell, Jiayi Wu, James J. Kowalczyk, Veronique Marceau, Silvio Campagna, Shawn E. R. Schiller, Bruce A. Littlefield
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 809.
Published: 01 May 2005
View article titled, <em>In vitro</em> and <em>in vivo</em> antitumor activities of novel hemiasterlin analog E7974
Journal Articles

Tubulin-based antimitotic mechanism of novel hemiasterlin analog E7974

Galina Kuznetsov, Murray J. Towle, Junke Liu, Hongsheng Cheng, Karen Tendyke, Jim J. Kowalczyk, Silvio Campagna, Bruce A. Littlefield
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 810.
Published: 01 May 2005
View article titled, Tubulin-based antimitotic mechanism of novel hemiasterlin analog E7974
Journal Articles

Induction of Morphological and Biochemical Apoptosis following Prolonged Mitotic Blockage by Halichondrin B Macrocyclic Ketone Analog E7389

Galina Kuznetsov, Murray J. Towle, Hongsheng Cheng, Takanori Kawamura, Karen TenDyke, Diana Liu, Yoshito Kishi, Melvin J. Yu, Bruce A. Littlefield
Journal: Cancer Research
Cancer Res (2004) 64 (16): 5760–5766.
https://doi.org/10.1158/0008-5472.CAN-04-1169
Published: 16 August 2004
View article titled, Induction of Morphological and Biochemical Apoptosis following Prolonged Mitotic Blockage by Halichondrin B Macrocyclic Ketone Analog E7389
Open the PDF for Induction of Morphological and Biochemical Apoptosis following Prolonged Mitotic Blockage by Halichondrin B Macrocyclic Ketone Analog E7389 in another window
Journal Articles

Novel proteasome inhibitors show potent anti-tumor efficacy

Kenichi Nomoto, Kozo Akasaka, Jiayi Wu, Erin Murphy, Yimin Jiang, Xiang-Yi Li, Karen Tendyke, Shawn Schiller, Catherine Reardon, Bruce Decosta, Christina Shaffer, Pamela McGuinness, Timothy Chamberlain, Huiming Zhang, Charles Johannes, Jean-Christophe Harmange, Mary W. Vermeulen
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 925.
Published: 01 April 2004
View article titled, Novel proteasome inhibitors show potent anti-tumor efficacy