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Journal Articles

Abstract 4824: Targeting CD30 as a novel treatment strategy in RANBP2-ALK-rearranged inflammatory myofibroblastic tumor

Ashleigh M. Fordham, James Blackburn, Erin E. Heyer, Jinhan Xie, Emily V. Mould, Andrew J. Gifford, Lisa T. Morgan, Carol Wadham, Mitali Fadia, Jamie I. Fletcher, Karen L. MacKenzie, Toby N. Trahair

Cancer Res (2019) 79 (13_Supplement): 4824.

https://doi.org/10.1158/1538-7445.AM2019-4824

Published: 01 July 2019

View articletitled, Abstract 4824: Targeting CD30 as a novel treatment strategy in RANBP2-ALK-rearranged inflammatory myofibroblastic tumor

Journal Articles

MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin

Rosemary O'Brien, Sieu L. Tran, Michelle F. Maritz, Bing Liu, Cheng Fei Kong, Stefania Purgato, Chen Yang, Jayne Murray, Amanda J. Russell, Claudia L. Flemming, Georg von Jonquieres, Hilda A. Pickett, Wendy B. London, Michelle Haber, Preethi H. Gunaratne, Murray D. Norris, Giovanni Perini, Jamie I. Fletcher, Karen L. MacKenzie

Cancer Res (2016) 76 (12): 3604–3617.

https://doi.org/10.1158/0008-5472.CAN-15-0879

Published: 14 June 2016

View articletitled, MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin

Includes: Supplementary data

Journal Articles

WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma

Cancer Res (2015) 75 (23): 5143–5154.

https://doi.org/10.1158/0008-5472.CAN-15-0423

Published: 30 November 2015

View articletitled, WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma

Includes: Supplementary data

Journal Articles

Abstract 488: High DKC1 expression supports neuroblastoma tumor cell proliferation and is strongly associated with poor patient outcomes

Rosemary O'Brien, Michelle F. Maritz, Cheng Fei Kong, Stefania Purgato, Bing Liu, Chen Yang, Amanda Russell, Jayne Murray, Claudia Flemming, Michelle Haber, Giovanni Perini, Murray D. Norris, Jamie I. Fletcher, Karen L. Mackenzie

Cancer Res (2015) 75 (15_Supplement): 488.

https://doi.org/10.1158/1538-7445.AM2015-488

Published: 01 August 2015

View articletitled, Abstract 488: High DKC1 expression supports neuroblastoma tumor cell proliferation and is strongly associated with poor patient outcomes

Journal Articles

Abstract 1378: The histone methyltransferase adaptor WDR5 is a novel cofactor in neuroblastoma

Yuting Sun, Pei Yan Liu, Daniel Carter, Nicolas Sokolowski, Karen L. MacKenzie, Glenn M. Marshall, Tao Liu

Cancer Res (2014) 74 (19_Supplement): 1378.

https://doi.org/10.1158/1538-7445.AM2014-1378

Published: 01 October 2014

View articletitled, Abstract 1378: The histone methyltransferase adaptor WDR5 is a novel cofactor in neuroblastoma

Journal Articles

Abstract 2196: Upregulation of survivin during immortalization is linked to repression of p16INK4a and confers resistance to oxidative stress

Carlotta Petti, Chin-Yi Kan, Philipp A. Dietrich, Bracken Lauryn, Ning Xu, Jun Yuan, Tao Liu, Karen L. MacKenzie

Cancer Res (2012) 72 (8_Supplement): 2196.

https://doi.org/10.1158/1538-7445.AM2012-2196

Published: 15 April 2012

View articletitled, Abstract 2196: Upregulation of survivin during immortalization is linked to repression of p16INK4a and confers resistance to oxidative stress

Journal Articles

Abstract 3027: SIRT1 promotes N-Myc oncogenesis stabilizing N-Myc protein

Glenn M. Marshall, Pei Y. Liu, Samuele Gherardi, Christopher J. Scarlett, Antonio Bedalov, Ning Xu, Nunzio Iraci, Karen L. MacKenzie, Michelle Haber, Murray D. Norris, Andrew V. Biankin, Giovanni Perini, Tao Liu

Cancer Res (2011) 71 (8_Supplement): 3027.

https://doi.org/10.1158/1538-7445.AM2011-3027

Published: 15 April 2011

View articletitled, Abstract 3027: SIRT1 promotes N-Myc oncogenesis stabilizing N-Myc protein

Journal Articles

Abstract 1110: Molecular and functional alterations associated with repression of tumor suppressor p16INK4a during immortalization of human endothelial cells

Victoria W. Wen, Flora Kan, Eddy Pasquier, Melissa Chang, Maria Kavallaris, Karen L. Mackenzie

Cancer Res (2010) 70 (8_Supplement): 1110.

https://doi.org/10.1158/1538-7445.AM10-1110

Published: 15 April 2010

View articletitled, Abstract 1110: Molecular and functional alterations associated with repression of tumor suppressor p16INK4a during immortalization of human endothelial cells

Journal Articles

p53 Determines Multidrug Sensitivity of Childhood Neuroblastoma

Chengyuan Xue, Michelle Haber, Claudia Flemming, Glenn M. Marshall, Richard B. Lock, Karen L. MacKenzie, Katerina V. Gurova, Murray D. Norris, Andrei V. Gudkov

Cancer Res (2007) 67 (21): 10351–10360.

https://doi.org/10.1158/0008-5472.CAN-06-4345

Published: 01 November 2007

View articletitled, p53 Determines Multidrug Sensitivity of Childhood Neuroblastoma

Journal Articles

Telomere-Driven Karyotypic Complexity Concurs with p16^INK4a Inactivation in TP53-Competent Immortal Endothelial Cells

Victoria W. Wen, Kaida Wu, Sheik Baksh, Rebecca A. Hinshelwood, Richard B. Lock, Susan J. Clark, Malcolm A.S. Moore, Karen L. MacKenzie

Cancer Res (2006) 66 (22): 10691–10700.

https://doi.org/10.1158/0008-5472.CAN-06-0979

Published: 15 November 2006

View articletitled, Telomere-Driven Karyotypic Complexity Concurs with p16INK4a Inactivation in TP53-Competent Immortal Endothelial Cells

Journal Articles

Telomere-driven karyotypic complexity concurs with p16INK4a repression in hTERT-immortalized endothelial cells

Victoria W. Wen, Kaida Wu, Sheik Bakshs, Malcolm A. S. Moore, Karen L. Mackenzie

Cancer Res (2006) 66 (8_Supplement): 1169.

Published: 15 April 2006

View articletitled, Telomere-driven karyotypic complexity concurs with p16INK4a repression in hTERT-immortalized endothelial cells

Journal Articles

Acquisition of anti-apoptotic potential in the process of telomerase-mediated immortalizaion of human fetal lung fibroblasts

Jun Yuan, Benjamin Ming-Pang Yang, Karen L. Mackenzie

Cancer Res (2006) 66 (8_Supplement): 1174.

Published: 15 April 2006

View articletitled, Acquisition of anti-apoptotic potential in the process of telomerase-mediated immortalizaion of human fetal lung fibroblasts

Journal Articles

Clonal analysis of crisis in bone marrow endothelial cells transduced with human telomerase reverse transcriptase (hTERT).

Victoria W. Wen, Kaida Wu, Sheik Baksh, Malcolm A. S. Moore, Karen L. Mackenzie

Cancer Res (2004) 64 (7_Supplement): 559.

Published: 01 April 2004

View articletitled, Clonal analysis of crisis in bone marrow endothelial cells transduced with human telomerase reverse transcriptase (hTERT).

Journal Articles

Limited Proliferation and Telomere Dysfunction following Telomerase Inhibition in Immortal Murine Fibroblasts

Jessica Boklan, Gouri Nanjangud, Karen L. MacKenzie, Chad May, Michel Sadelain, Malcolm A. S. Moore

Cancer Res (2002) 62 (7): 2104–2114.

Published: 01 April 2002

View articletitled, Limited Proliferation and Telomere Dysfunction following Telomerase Inhibition in Immortal Murine Fibroblasts

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Abstract 4824: Targeting CD30 as a novel treatment strategy in RANBP2-ALK-rearranged inflammatory myofibroblastic tumor

MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin

WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma

Abstract 488: High DKC1 expression supports neuroblastoma tumor cell proliferation and is strongly associated with poor patient outcomes

Abstract 1378: The histone methyltransferase adaptor WDR5 is a novel cofactor in neuroblastoma

Abstract 2196: Upregulation of survivin during immortalization is linked to repression of p16INK4a and confers resistance to oxidative stress

Abstract 3027: SIRT1 promotes N-Myc oncogenesis stabilizing N-Myc protein

Abstract 1110: Molecular and functional alterations associated with repression of tumor suppressor p16INK4a during immortalization of human endothelial cells

p53 Determines Multidrug Sensitivity of Childhood Neuroblastoma

Telomere-Driven Karyotypic Complexity Concurs with p16^INK4a Inactivation in TP53-Competent Immortal Endothelial Cells

Telomere-driven karyotypic complexity concurs with p16INK4a repression in hTERT-immortalized endothelial cells

Acquisition of anti-apoptotic potential in the process of telomerase-mediated immortalizaion of human fetal lung fibroblasts

Clonal analysis of crisis in bone marrow endothelial cells transduced with human telomerase reverse transcriptase (hTERT).

Limited Proliferation and Telomere Dysfunction following Telomerase Inhibition in Immortal Murine Fibroblasts

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