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Karen Clise-Dwyer
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Journal Articles

Abstract 44: A novel, codon-based method to modulate off-tumor toxicity of chimeric antigen receptor (CAR) T cells

Rolando A. Vedia, Sijie Lu, Anne V. Philips, Anna Sergeeva, Lisa S. St John, Karen Clise-Dwyer, Gheath Alatrash, Jeffrey J. Molldrem
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 44.
https://doi.org/10.1158/1538-7445.AM2024-44
Published: 22 March 2024
View article titled, Abstract 44: A novel, codon-based method to modulate off-tumor toxicity of chimeric antigen receptor (CAR) T cells
Journal Articles

Abstract 669: Immunophenotyping of human brain tumors reveals myeloid cell mediated anti-glioma axis

Pravesh Gupta, Minghao Dang, Shivangi Oberai, Mekenzie Peshoff, Nancy Milam, Aml Ahmed, Krishna Bojja, Tuan M. Tran, Kathryn Cox, Huma Shehwana, Carlos Kamiya Matsuoka, Jianzhuo Li, Joy Gumin, Alicia Goldman, Sameer A. Seth, Atul Maheshwari, Frederick F. Lang, Nicholas E. Navin, Amy B. Heimberger, Karen Clise Dwyer, Linghua Wang, Krishna P. Bhat
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 669.
https://doi.org/10.1158/1538-7445.AM2023-669
Published: 04 April 2023
View article titled, Abstract 669: Immunophenotyping of human brain tumors reveals myeloid cell mediated anti-glioma axis
Journal Articles

Abstract 1348: LMW-E induction and crosstalk with immune cells potentiates local immune responses leading to an immunosuppressive microenvironment at the early stages of breast tumorigenesis in mouse models

Sofia Mastoraki, Amriti R. Lulla, Sarah Schneider, Karen Clise-Dwyer, Morgan M. Green, Natalie W. Fowlkes, Kelly K. Hunt, Stephanie S. Watowich, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1348.
https://doi.org/10.1158/1538-7445.AM2022-1348
Published: 15 June 2022
View article titled, Abstract 1348: LMW-E induction and crosstalk with immune cells potentiates local immune responses leading to an immunosuppressive microenvironment at the early stages of breast tumorigenesis in mouse models
Journal Articles

Abstract 5545: Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration

Yifan Zhou, Yusra B. Medik, Bhakti Patel, Daniel B. Zamler, Sijie Chen, Thomas Chapman, Sarah Schneider, Rachel L. Babcock, Taylor T. Chrisikos, Laura M. Kahn, Allison M. Dyevoich, Elizabeth M. Park, Alexandria P. Cogdill, Daniel H. Johnson, Sarah B. Johnson, Khalida M. Wani, Debora A. Ledesma, Courtney W. Hudgens, Jingjing Wang, Md Abdul Wadud Khan, Aron Y. Joon, Weiyi Peng, Haiyan S. Li, Reetakshi Arora, Ximing Tang, Maria Gabriela Raso, Xuegong Zhang, Wai Chin Foo, Michael T. Tetzlaff, Gretchen E. Diehl, Karen Clise-Dwyer, Elizabeth M. Whitley, Matthew M. Gubin, James P. Allison, Patrick Hwu, Nadim J. Ajami, Adi Diab, Jennifer A. Wargo, Stephanie S. Watowich
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5545.
https://doi.org/10.1158/1538-7445.AM2022-5545
Published: 15 June 2022
View article titled, Abstract 5545: Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration
Journal Articles

Abstract 1516: Deep profiling of T-cell repertoire and tumor heterogeneity in chronic lymphocytic leukemia patients following allogeneic T-cell therapy

Celine Kerros, John P. Miller, Xizeng Mao, Haven R. Garber, Hannah C. Beird, Jianhua Zhang, Jason Roszik, Paul Leonard, Li Zhao, Sahil Seth, Pei Lin, Huandong Sun, William G. Wierda, Issa F. Khouri, Karen Clise-Dwyer, Andrew Futreal, Shoudan Liang, Koppikar Priya, Jeffrey Molldrem
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1516.
https://doi.org/10.1158/1538-7445.AM2020-1516
Published: 15 August 2020
View article titled, Abstract 1516: Deep profiling of T-cell repertoire and tumor heterogeneity in chronic lymphocytic leukemia patients following allogeneic T-cell therapy
Journal Articles

Trastuzumab Increases HER2 Uptake and Cross-Presentation by Dendritic Cells

Victor A. Gall, Anne V. Philips, Na Qiao, Karen Clise-Dwyer, Alexander A. Perakis, Mao Zhang, Guy T. Clifton, Pariya Sukhumalchandra, Qing Ma, Sangeetha M. Reddy, Dihua Yu, Jeffrey J. Molldrem, George E. Peoples, Gheath Alatrash, Elizabeth A. Mittendorf
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (19): 5374–5383.
https://doi.org/10.1158/0008-5472.CAN-16-2774
Published: 01 October 2017
View article titled, Trastuzumab Increases HER2 Uptake and Cross-Presentation by Dendritic Cells
Open the PDF for Trastuzumab Increases HER2 Uptake and Cross-Presentation by Dendritic Cells in another window
Includes: Supplementary data
Journal Articles

Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination

Hong Jiang, Yisel Rivera-Molina, Candelaria Gomez-Manzano, Karen Clise-Dwyer, Laura Bover, Luis M. Vence, Ying Yuan, Frederick F. Lang, Carlo Toniatti, Mohammad B. Hossain, Juan Fueyo
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (14): 3894–3907.
https://doi.org/10.1158/0008-5472.CAN-17-0468
Published: 13 July 2017
View article titled, Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination
Open the PDF for Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination in another window
Includes: Supplementary data
Journal Articles

Abstract 3680: Cancer-killing viruses combined with tumor-targeting immune checkpoint modulation elicits an in situ vaccination effect and expansion of tumor-specific T cells responsible for efficacious systemic anti-cancer activity

Hong Jiang, Andrew Dong, Yisel Rivera-Molina, Karen Clise-Dwyer, Xuejun Fan, Francisco W. Martinez, Teresa Nguyen, Verlene Henry, Caroline Carrillo, Candelaria Gomez-Manzano, Juan Fueyo
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3680.
https://doi.org/10.1158/1538-7445.AM2017-3680
Published: 01 July 2017
View article titled, Abstract 3680: Cancer-killing viruses combined with tumor-targeting immune checkpoint modulation elicits an <em>in situ</em> vaccination effect and expansion of tumor-specific T cells responsible for efficacious systemic anti-cancer activity
Journal Articles

Abstract LB-222: Long-term subclonal evolution of CLL from immune selective pressure after allogeneic stem cell transplant and donor lymphocyte infusion

Haven R. Garber, Hannah Beird, Yu Cao, Jianhua Zhang, Rachel Sargent, Pei Lin, Sahil Seth, Xingzhi Song, Huandong Sun, Xizeng Mao, Lisa St John, Karen Clise-Dwyer, Gheath Alatrash, P. Andrew Futreal, Jeffrey J. Molldrem
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-222.
https://doi.org/10.1158/1538-7445.AM2015-LB-222
Published: 01 August 2015
View article titled, Abstract LB-222: Long-term subclonal evolution of CLL from immune selective pressure after allogeneic stem cell transplant and donor lymphocyte infusion
Journal Articles

Abstract 280: Delta-24-RGDOX: making cancer more “visible” to the immune system

Hong Jiang, Xuejun Fan, Karen Clise-Dwyer, Laura Bover, Joy Gumin, Kathryn E. Ruisaard, Farah J. Mukheef, Frederick F. Lang, Candelaria Gomez-Manzano, Juan Fueyo
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 280.
https://doi.org/10.1158/1538-7445.AM2015-280
Published: 01 August 2015
View article titled, Abstract 280: Delta-24-RGDOX: making cancer more “visible” to the immune system
Journal Articles

Breast Cancer Cell Uptake of the Inflammatory Mediator Neutrophil Elastase Triggers an Anticancer Adaptive Immune Response

Elizabeth A. Mittendorf, Gheath Alatrash, Na Qiao, Yun Wu, Pariya Sukhumalchandra, Lisa S. St. John, Anne V. Philips, Haile Xiao, Mao Zhang, Kathryn Ruisaard, Karen Clise-Dwyer, Sijie Lu, Jeffrey J. Molldrem
Journal: Cancer Research
Cancer Res (2012) 72 (13): 3153–3162.
https://doi.org/10.1158/0008-5472.CAN-11-4135
Published: 01 July 2012
View article titled, Breast Cancer Cell Uptake of the Inflammatory Mediator Neutrophil Elastase Triggers an Anticancer Adaptive Immune Response
Open the PDF for Breast Cancer Cell Uptake of the Inflammatory Mediator Neutrophil Elastase Triggers an Anticancer Adaptive Immune Response in another window
Includes: Supplementary data
Journal Articles

Abstract 788: Uptake and cross-presentation of the leukemia associated antigens neutrophil elastase (NE) and proteinase-3 (P3) increases susceptibility of solid tumors to PR1-targeted immunotherapy

Gheath Alatrash, Elizabeth Mittendorf, Anna Sergeeva, Pariya Sukhumalchandra, Na Qiao, Mao Zhang, Kathryn Quintanilla, Haile Xiao, Karen Clise-Dwyer, Sijie Lu, Jeffrey Molldrem
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 788.
https://doi.org/10.1158/1538-7445.AM2011-788
Published: 15 April 2011
View article titled, Abstract 788: Uptake and cross-presentation of the leukemia associated antigens neutrophil elastase (NE) and proteinase-3 (P3) increases susceptibility of solid tumors to PR1-targeted immunotherapy
Journal Articles

Abstract 801: Uptake of exogenous neutrophil elastase by breast cancer cells: A novel link between innate immunity, inflammation and breast cancer immunity

Elizabeth A. Mittendorf, Gheath Alatrash, Na Qiao, Haile Xiao, Pariya Sukhumalchandra, Kathryn Quintanilla, Karen Clise-Dwyer, Jeffrey Molldrem
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 801.
https://doi.org/10.1158/1538-7445.AM2011-801
Published: 15 April 2011
View article titled, Abstract 801: Uptake of exogenous neutrophil elastase by breast cancer cells: A novel link between innate immunity, inflammation and breast cancer immunity
Journal Articles

The Warburg Effect in Leukemia-Stroma Cocultures Is Mediated by Mitochondrial Uncoupling Associated with Uncoupling Protein 2 Activation

Ismael Samudio, Michael Fiegl, Teresa McQueen, Karen Clise-Dwyer, Michael Andreeff
Journal: Cancer Research
Cancer Res (2008) 68 (13): 5198–5205.
https://doi.org/10.1158/0008-5472.CAN-08-0555
Published: 01 July 2008
View article titled, The Warburg Effect in Leukemia-Stroma Cocultures Is Mediated by Mitochondrial Uncoupling Associated with Uncoupling Protein 2 Activation
Open the PDF for The Warburg Effect in Leukemia-Stroma Cocultures Is Mediated by Mitochondrial Uncoupling Associated with Uncoupling Protein 2 Activation in another window
Includes: Supplementary data