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Kaoru Kiguchi
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Journal Articles

Abstract 2044: Lin neg Sca-1high CD49f high prostate cancer cells derived from Hi-Myc mice are tumor-initiating cells with basal-epithelial characteristics and differentiation potential in vitro and in vivo

Jorge M. Blando, Achinto Saha, Irina Fernandez, Kaoru Kiguchi, John DiGiovanni
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2044.
https://doi.org/10.1158/1538-7445.AM2014-2044
Published: 01 October 2014
View article titled, Abstract 2044: Lin neg Sca-1high CD49f high prostate cancer cells derived from Hi-Myc mice are tumor-initiating cells with basal-epithelial characteristics and differentiation potential in vitro and in vivo
Journal Articles

Abstract 5355: Twist1 regulates the cell cycle and proliferative capacity of keratinocytes during tumor promotion

Jaya Srivastava, Everardo Macias, Kaoru Kiguchi, John DiGiovanni
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5355.
https://doi.org/10.1158/1538-7445.AM2014-5355
Published: 01 October 2014
View article titled, Abstract 5355: Twist1 regulates the cell cycle and proliferative capacity of keratinocytes during tumor promotion
Journal Articles

Abstract 3704: Evaluation of curcumin in combination with 6-shogaol and epicatechin for the chemoprevention of prostate cancer.

Achinto Saha, Jorge Blando, Kaoru Kiguchi, John DiGiovanni
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3704.
https://doi.org/10.1158/1538-7445.AM2013-3704
Published: 15 April 2013
View article titled, Abstract 3704: Evaluation of curcumin in combination with 6-shogaol and epicatechin for the chemoprevention of prostate cancer.
Journal Articles

Abstract 1290: Investigations to evaluate the role of Twist1 during tumor promotion and epithelial carcinogenesis.

Jaya Srivastava, Everardo Macias, Dharanija Rao, Kaoru Kiguchi, John DiGiovanni
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1290.
https://doi.org/10.1158/1538-7445.AM2013-1290
Published: 15 April 2013
View article titled, Abstract 1290: Investigations to evaluate the role of Twist1 during tumor promotion and epithelial carcinogenesis.
Journal Articles

Abstract 179: Impact of diet-induced obesity on inflamatory pathways during prostate cancer progression in Hi-Myc mice.

Jorge M. Blando, Kaoru Kiguchi, Irina Fernandez, John DiGiovanni
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 179.
https://doi.org/10.1158/1538-7445.AM2013-179
Published: 15 April 2013
View article titled, Abstract 179: Impact of diet-induced obesity on inflamatory pathways during prostate cancer progression in Hi-Myc mice.
Journal Articles

Abstract 1331: The BK5.erbB2 mouse as a novel model of esophageal adenocarcinoma

Takuya Kitamura, Yoshimi Homma, John DiGiovanni, Kaoru Kiguchi
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1331.
https://doi.org/10.1158/1538-7445.AM2012-1331
Published: 15 April 2012
View article titled, Abstract 1331: The BK5.erbB2 mouse as a novel model of esophageal adenocarcinoma
Journal Articles

Abstract 2559: Targeting mTORC1 may provide selectivity for inhibiting proliferation of hair follicle stem/progenitor cells during tumor promotion

Okkyung Rho, Kaoru Kiguchi, John DiGiovanni
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2559.
https://doi.org/10.1158/1538-7445.AM2012-2559
Published: 15 April 2012
View article titled, Abstract 2559: Targeting mTORC1 may provide selectivity for inhibiting proliferation of hair follicle stem/progenitor cells during tumor promotion
Journal Articles

Abstract 5423: Diet induced obesity, inflammation and prostate cancer progression in Hi-Myc mice

Jorge M. Blando, Kaoru Kiguchi, John DiGiovanni
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5423.
https://doi.org/10.1158/1538-7445.AM2012-5423
Published: 15 April 2012
View article titled, Abstract 5423: Diet induced obesity, inflammation and prostate cancer progression in Hi-Myc mice
Journal Articles

Abstract 4300: Constitutive activation of Stat3 increases hair follicle progenitor population at the expense of bulge region keratinocyte stem cells

Dharanija Rao, Steve Carbajal, Kaoru Kiguchi, John DiGiovanni
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4300.
https://doi.org/10.1158/1538-7445.AM10-4300
Published: 15 April 2010
View article titled, Abstract 4300: Constitutive activation of Stat3 increases hair follicle progenitor population at the expense of bulge region keratinocyte stem cells
Journal Articles

Abstract 4176: Bile acid-promoted esophageal and forestomach carcinomas in BK5.erbB2 mice

Takuya Kitamura, Kevin Connolly, Aline Lueckgen, John DiGiovanni, Kaoru Kiguchi
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4176.
https://doi.org/10.1158/1538-7445.AM10-4176
Published: 15 April 2010
View article titled, Abstract 4176: Bile acid-promoted esophageal and forestomach carcinomas in BK5.erbB2 mice
Journal Articles

Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation

Dae Joon Kim, Ken Kataoka, Dharanija Rao, Kaoru Kiguchi, George Cotsarelis, John DiGiovanni
Journal: Cancer Research
Cancer Res (2009) 69 (19): 7587–7594.
https://doi.org/10.1158/0008-5472.CAN-09-1180
Published: 01 October 2009
View article titled, Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation
Open the PDF for Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation in another window
Journal Articles

Abstract #4915: Impact of p53 deficiency on development of tumors in uterine cervix of IGF-1 transgenic mice

Takashi Matsumoto, Kaoru Kiguchi, Linda Beltran, Kazuo Miyoshi, Katsumi Kito, Takayoshi Nogawa, Masamichi Hiura, Norifumi Ueda, John Digiovanni
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4915.
Published: 01 May 2009
View article titled, Abstract #4915: Impact of p53 deficiency on development of tumors in uterine cervix of IGF-1 transgenic mice
Journal Articles

Abstract #4100: Impact of Bcl-xL deficiency in mouse keratinocytes on susceptibility to both UVB- and chemically-induced skin carcinogenesis

Dae Kim, Ken Kataoka, Shigetoshi Sano, Kaoru Kiguchi, John DiGiovanni
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4100.
Published: 01 May 2009
View article titled, Abstract #4100: Impact of Bcl-x<sub>L</sub> deficiency in mouse keratinocytes on susceptibility to both UVB- and chemically-induced skin carcinogenesis
Journal Articles

Abstract #4764: The role of bile acids and erbB2 activation in the development of biliary tract cancer

Takuya Kitamura, Kevin Connolly, John DiGiovanni, Kaoru Kiguchi
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4764.
Published: 01 May 2009
View article titled, Abstract #4764: The role of bile acids and erbB2 activation in the development of biliary tract cancer
Journal Articles

Abstract #4107: Impact of Stat3 activation on target cells for skin tumor development

Dharanija Rao, Dae Kim, Steve Carbajal, Kaoru Kiguchi, John DiGiovanni
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4107.
Published: 01 May 2009
View article titled, Abstract #4107: Impact of Stat3 activation on target cells for skin tumor development
Journal Articles

Abstract #4549: The inhibitory effects of the histone deacetylase (HDAC) inhibitor, PCI-24781, alters growth of gallbladder cancer cells and downregulate erbB2 expression

Kaoru Kiguchi, Takuya Kitamura, Tetsuo Ajiki, Kevin Connolly, John DiGiovanni
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4549.
Published: 01 May 2009
View article titled, Abstract #4549: The inhibitory effects of the histone deacetylase (HDAC) inhibitor, PCI-24781, alters growth of gallbladder cancer cells and downregulate erbB2 expression
Journal Articles

Akt Activation Synergizes with Trp53 Loss in Oral Epithelium to Produce a Novel Mouse Model for Head and Neck Squamous Cell Carcinoma

Marta Moral, Carmen Segrelles, M. Fernanda Lara, Ana Belén Martínez-Cruz, Corina Lorz, Mirentxu Santos, Ramón García-Escudero, Jerry Lu, Kaoru Kiguchi, Agueda Buitrago, Clotilde Costa, Cristina Saiz, Jose L. Rodriguez-Peralto, Francisco J. Martinez-Tello, Maria Rodriguez-Pinilla, Montserrat Sanchez-Cespedes, Marina Garín, Teresa Grande, Ana Bravo, John DiGiovanni, Jesús M. Paramio
Journal: Cancer Research
Cancer Res (2009) 69 (3): 1099–1108.
https://doi.org/10.1158/0008-5472.CAN-08-3240
Published: 29 January 2009
View article titled, Akt Activation Synergizes with <em>Trp53</em> Loss in Oral Epithelium to Produce a Novel Mouse Model for Head and Neck Squamous Cell Carcinoma
Open the PDF for Akt Activation Synergizes with <em>Trp53</em> Loss in Oral Epithelium to Produce a Novel Mouse Model for Head and Neck Squamous Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Evaluation of a mouse gallbladder cancer cell line for tumorigenicity and preclinical therapeutic efficacy studies

Takuya Kitamura, Mikiro Takaishi, Kevin Connolly, John DiGiovanni, Kaoru Kiguchi
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2949.
Published: 01 May 2008
View article titled, Evaluation of a mouse gallbladder cancer cell line for tumorigenicity and preclinical therapeutic efficacy studies
Journal Articles

COX-2 driven inflammation establishes a protumorigenic state in pancreas: the BK5.COX-2 mouse model of pancreatic cancer

Jennifer Colby, Russell Klein, Kaoru Kiguchi, Penny Riggs, Mark McArthur, Claudio Conti, Joyce Rundhaug, Amy Pavone, Susan Fischer
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5866.
Published: 01 May 2008
View article titled, COX-2 driven inflammation establishes a protumorigenic state in pancreas: the BK5.COX-2 mouse model of pancreatic cancer
Journal Articles

Effects of histone deacetylase (HDAC) inhibitor PCI-24781 on the development of gallbladder carcinoma in BK5.erbB2 mice

Kaoru Kiguchi, Kevin Connolly, Takuya Kitamura, Lynssie Ruffino, John DiGiovanni
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2447.
Published: 01 May 2008
View article titled, Effects of histone deacetylase (HDAC) inhibitor PCI-24781 on the development of gallbladder carcinoma in BK5.erbB2 mice