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Kakajan Komurov
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Journal Articles

A Multimodal Drug–Diet–Immunotherapy Combination Restrains Melanoma Progression and Metastasis

Nicole Oatman, Mruniya V. Gawali, Sunny Congrove, Román Cáceres, Abitha Sukumaran, Nishtha Gupta, Narmadha Murugesan, Priyanka Arora, Srividhya Subramanian, Kwangmin Choi, Zalfa Abdel-Malek, Julie A. Reisz, Daniel Stephenson, Ravi Amaravadi, Pankaj Desai, Angelo D’Alessandro, Kakajan Komurov, Biplab Dasgupta
Journal: Cancer Research
Cancer Res (2024) 84 (14): 2333–2351.
https://doi.org/10.1158/0008-5472.CAN-23-1635
Published: 15 July 2024
View article titled, A Multimodal Drug–Diet–Immunotherapy Combination Restrains Melanoma Progression and Metastasis
Open the PDF for A Multimodal Drug–Diet–Immunotherapy Combination Restrains Melanoma Progression and Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 1599: Targeting tumor synthetic vulnerabilities and immune evasion mechanisms with CO-1002

Daniel Ciznadija, Gemechis Degaga, Abdul Mondal, Maxwell Hillbert, Cong Chen, Bikash Debnath, Sonam Mehrotra, Brandon Jones, Ralph Rivero, Kakajan Komurov
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1599.
https://doi.org/10.1158/1538-7445.AM2023-1599
Published: 04 April 2023
View article titled, Abstract 1599: Targeting tumor synthetic vulnerabilities and immune evasion mechanisms with CO-1002
Journal Articles

Abstract 1548: CO-1008, an ADC program targeting leukemic progenitor and blast AML cells, but not normal hematopoetic progenitor cells

Garima Kaushik, Bandana Vishwakarma, Marina Bell, Kakajan Komurov
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1548.
https://doi.org/10.1158/1538-7445.AM2023-1548
Published: 04 April 2023
View article titled, Abstract 1548: CO-1008, an ADC program targeting leukemic progenitor and blast AML cells, but not normal hematopoetic progenitor cells
Journal Articles

Abstract 5836: Autophagy inhibition as a new therapeutic strategy for cancers with transcription elongation defects

Belal Muhammad, Lisa Vinnedge, KAkajan Komurov
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5836.
https://doi.org/10.1158/1538-7445.AM2020-5836
Published: 15 August 2020
View article titled, Abstract 5836: Autophagy inhibition as a new therapeutic strategy for cancers with transcription elongation defects
Journal Articles

Abstract 1399: Passenger deletion vulnerability in glioblastoma

Nicole Oatman, Kakajan Komurov, Priyanka Arora, Pankaj Desai, Nupur Dasgupta, Kwangmin Choi, Biplab Dasgupta
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1399.
https://doi.org/10.1158/1538-7445.AM2018-1399
Published: 01 July 2018
View article titled, Abstract 1399: Passenger deletion vulnerability in glioblastoma
Journal Articles

Abstract A2-53: Integrative systems analyses reveal addiction of HER2+ breast cancers to ERAD for survival

Navneet Singh, Rashika Joshi, Kakajan Komurov
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_1): A2-53.
https://doi.org/10.1158/1538-7445.TRANSCAGEN-A2-53
Published: 15 November 2015
View article titled, Abstract A2-53: Integrative systems analyses reveal addiction of HER2+ breast cancers to ERAD for survival
Journal Articles

Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma

Y.N. Vashisht Gopal, Helen Rizos, Guo Chen, Wanleng Deng, Dennie T. Frederick, Zachary A. Cooper, Richard A. Scolyer, Gulietta Pupo, Kakajan Komurov, Vasudha Sehgal, Jiexin Zhang, Lalit Patel, Cristiano G. Pereira, Bradley M. Broom, Gordon B. Mills, Prahlad Ram, Paul D. Smith, Jennifer A. Wargo, Georgina V. Long, Michael A. Davies
Journal: Cancer Research
Cancer Res (2014) 74 (23): 7037–7047.
https://doi.org/10.1158/0008-5472.CAN-14-1392
Published: 30 November 2014
View article titled, Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma
Open the PDF for Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma in another window
Includes: Supplementary data
Journal Articles

Abstract C17: Revealing targetable cancer cell vulnerabilities by in silico pathway profiling

Rashika Joshi, Kakajan Komurov
Journal: Cancer Research
Cancer Res (2013) 73 (19_Supplement): C17.
https://doi.org/10.1158/1538-7445.FBCR13-C17
Published: 15 May 2014
View article titled, Abstract C17: Revealing targetable cancer cell vulnerabilities by in silico pathway profiling
Journal Articles

Abstract C16: Mapping synthetic vulnerabilities in non-small cell lung cancer

Hyun Seok Kim, Saurabh Mendiratta, Jiyeon Kim, Chad Victor Pecot, Jill E. Larsen, Iryna Zubovych, Bo Yeun Seo, Jimi Kim, Banu Eskiocak, Hannah Chung, Elizabeth McMillan, Sherry Wu, Jef De Brabander, Kakajan Komurov, Bruce A. Posner, Rolf Brekken, Anil K. Sood, Ralph J. Deberardinis, Michael G. Roth, John D. Minna, Michael A. White
Journal: Cancer Research
Cancer Res (2013) 73 (19_Supplement): C16.
https://doi.org/10.1158/1538-7445.FBCR13-C16
Published: 15 May 2014
View article titled, Abstract C16: Mapping synthetic vulnerabilities in non-small cell lung cancer
Journal Articles

Functional Parsing of Driver Mutations in the Colorectal Cancer Genome Reveals Numerous Suppressors of Anchorage-Independent Growth

Ugur Eskiocak, Sang Bum Kim, Peter Ly, Andres I. Roig, Sebastian Biglione, Kakajan Komurov, Crystal Cornelius, Woodring E. Wright, Michael A. White, Jerry W. Shay
Journal: Cancer Research
Cancer Res (2011) 71 (13): 4359–4365.
https://doi.org/10.1158/0008-5472.CAN-11-0794
Published: 30 June 2011
View article titled, Functional Parsing of Driver Mutations in the Colorectal Cancer Genome Reveals Numerous Suppressors of Anchorage-Independent Growth
Open the PDF for Functional Parsing of Driver Mutations in the Colorectal Cancer Genome Reveals Numerous Suppressors of Anchorage-Independent Growth in another window
Includes: Supplementary data
Journal Articles

Abstract 708: Integrated analysis of drug resistance networks in breast cancer

Kakajan Komurov, Jen-Te Tseng, Melissa Muller, Prahlad T. Ram
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 708.
https://doi.org/10.1158/1538-7445.AM2011-708
Published: 15 April 2011
View article titled, Abstract 708: Integrated analysis of drug resistance networks in breast cancer
Journal Articles

Abstract 2207: Functional interrogation of the colorectal cancer genome identifies numerous suppressors of anchorage-independent growth

Ugur Eskiocak, Sang B. Kim, Peter Ly, Andres I. Roig, Sebastian Biglione, Kakajan Komurov, Crystal Cornelius, Woodring E. Wright, Michael A. White, Jerry W. Shay
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2207.
https://doi.org/10.1158/1538-7445.AM2011-2207
Published: 15 April 2011
View article titled, Abstract 2207: Functional interrogation of the colorectal cancer genome identifies numerous suppressors of anchorage-independent growth
Journal Articles

Abstract 5032: Targeting Src in mucinous ovarian carcinoma

Koji Matsuo, Masato Nishimura, Rebbeca L. Stone, Kakajan Komurov, Mian MK Shahzad, Justin N. Bottsford-Miller, Takayuki Enomoto, Tadashi Kimura, Prahlad T. Ram, Kathleen M. Schmeler, Michael Frumovitz, Gary G. Gallick, Kwong K. Wong, Anil K. Sood
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5032.
https://doi.org/10.1158/1538-7445.AM2011-5032
Published: 15 April 2011
View article titled, Abstract 5032: Targeting Src in mucinous ovarian carcinoma
Journal Articles

Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in Braf-Mutant Human Cutaneous Melanoma Cells

Y.N. Vashisht Gopal, Wanleng Deng, Scott E. Woodman, Kakajan Komurov, Prahlad Ram, Paul D. Smith, Michael A. Davies
Journal: Cancer Research
Cancer Res (2010) 70 (21): 8736–8747.
https://doi.org/10.1158/0008-5472.CAN-10-0902
Published: 31 October 2010
View article titled, Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in <em>Braf-</em>Mutant Human Cutaneous Melanoma Cells
Open the PDF for Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in <em>Braf-</em>Mutant Human Cutaneous Melanoma Cells in another window
Includes: Supplementary data
Journal Articles

Abstract #SY08-3: Towards functional annotation of the cancer genome

Angelique Whitehurst, Kakajan Komurov, Michael White
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): SY08-3.
Published: 01 May 2009
View article titled, Abstract #SY08-3: Towards functional annotation of the cancer genome