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Justin M. Drake
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Journal Articles

Abstract 6357: A liquid biopsy-based targeted proteomic assay to identify druggable proteins from circulating tumor cells (CTCs)

Free
Alec Horrmann, Ali T. Arafa, Kaylee Kamalanathan, Alexa Hesch, Grant Schaap, Mahdi Ahmadi, Nathaniel Bristow, Badrinath Konety, Howard Scher, Emmanuel S. Antonarakis, Jiarong Hong, Justin M. Drake
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6357.
https://doi.org/10.1158/1538-7445.AM2025-6357
Published: 21 April 2025
View articletitled, Abstract 6357: A liquid biopsy-based targeted proteomic assay to identify druggable proteins from circulating tumor cells (CTCs)
Journal Articles

Abstract 6965: Characterizing the proteome landscape of extracellular vesicles from prostate cancer cell lines by mass spectrometry

Free
Megan L. Ludwig, Abderrahman Day, Hannah E. Bergom, Zoi Sychev, Alec Horrmann, Justin Hwang, Justin M. Drake
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6965.
https://doi.org/10.1158/1538-7445.AM2024-6965
Published: 22 March 2024
View articletitled, Abstract 6965: Characterizing the proteome landscape of extracellular vesicles from prostate cancer cell lines by mass spectrometry
Journal Articles

Abstract 6078: Circulating tumor cell-based early detection of breast cancer

Free
Justin M. Drake, Kaylee J. Kamalanathan, Catalina Galeano-Garces, Nathaniel Bristow, Nicholas Heller, Mahdi Ahmadi, Olivia Hedeen, Alexa Hesch, Grant Schaap, Joel Hapke, Jeff Miller, Ivo Babris, Tuan Le, Tony Clacko, Jiarong Hong, Badri Konety, Jayant Parthasarathy
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6078.
https://doi.org/10.1158/1538-7445.AM2024-6078
Published: 22 March 2024
View articletitled, Abstract 6078: Circulating tumor cell-based early detection of breast cancer
Journal Articles

Abstract 6563: PSMA-based detection and global proteome-based analysis of circulating tumor cells in castration resistant prostate cancer patients

Free
Justin M. Drake, Ali Arafa, Alec Horrmann, Kaylee J. Kamalanathan, Catalina Galeano-Garces, Zoi Sychev, Nicholas Heller, Mahdi Ahmadi, Megan Ludwig, Olivia Hedeen, Alexa Hesch, Grant Schaap, Joel Hapke, Jeff Miller, Ivo Babris, Tuan Lee, Tony Clacko, Justin Hwang, Jiarong Hong, Badri Konety, Jayant Parthasarathy, Emmanuel Antonarakis
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6563.
https://doi.org/10.1158/1538-7445.AM2024-6563
Published: 22 March 2024
View articletitled, Abstract 6563: PSMA-based detection and global proteome-based analysis of circulating tumor cells in castration resistant prostate cancer patients
Journal Articles

Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity

Free
Dominik Awad, Pham Hong Anh Cao, Thomas L. Pulliam, Meredith Spradlin, Elavarasan Subramani, Tristen V. Tellman, Caroline F. Ribeiro, Riccardo Muzzioli, Brittany E. Jewell, Hubert Pakula, Jeffrey J. Ackroyd, Mollianne M. Murray, Jenny J. Han, Mei Leng, Antrix Jain, Badrajee Piyarathna, Jingjing Liu, Xingzhi Song, Jianhua Zhang, Albert R. Klekers, Justin M. Drake, Michael M. Ittmann, Cristian Coarfa, David Piwnica-Worms, Mary C. Farach-Carson, Massimo Loda, Livia S. Eberlin, Daniel E. Frigo
Journal: Cancer Research
Cancer Res (2024) 84 (5): 703–724.
https://doi.org/10.1158/0008-5472.CAN-23-0555
Published: 04 March 2024
View articletitled, Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity
Open the PDF for Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity in another window
Includes: Supplementary data
Journal Articles

Abstract A020: Deciphering DNA damage repair in ATM mutant prostate cancers

Free
Mia E. Hofstad, Lan Yu, Andrea Woods, Zoi E. Sychev, Alice Mazzagatti, Xiaofang Huo, Ralf Kittler, Peter Ly, Justin M. Drake, Ganesh V. Raj
Journal: Cancer Research
Cancer Res (2024) 84 (1_Supplement): A020.
https://doi.org/10.1158/1538-7445.DNAREPAIR24-A020
Published: 09 January 2024
View articletitled, Abstract A020: Deciphering DNA damage repair in ATM mutant prostate cancers
Journal Articles

Abstract B071: Evaluating the synergy between enzalutamide and SRC kinase inhibitors against castration-resistant prostate cancer

Free
Ralph E. White, Victor Tan, Maxwell Bannister, Hai Dang Nguyen, Justin M. Drake
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B071.
https://doi.org/10.1158/1538-7445.PRCA2023-B071
Published: 02 June 2023
View articletitled, Abstract B071: Evaluating the synergy between enzalutamide and SRC kinase inhibitors against castration-resistant prostate cancer
Journal Articles

Abstract B070: Global proteomics and phosphoproteomics profiling of prostate cancer patient derived xenografts tumors from the LuCaP series

Free
Zoi E. Sychev, Gabbrianne E. Larson, Hannah E. Bergom, Abderrahman E. Day, Megan E. Ludwig, Atef E. Ali, Eva Corey, Stephen R. Plymate, Justin E. Hwang, Justin M. Drake
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B070.
https://doi.org/10.1158/1538-7445.PRCA2023-B070
Published: 02 June 2023
View articletitled, Abstract B070: Global proteomics and phosphoproteomics profiling of prostate cancer patient derived xenografts tumors from the LuCaP series
Journal Articles

Abstract B047: Characterizing the landscape of extracellular vesicles from prostate cancer cell lines

Free
Megan Ludwig, Zoi Sychev, Abderrahman Day, Hannah Bergom, Justin Hwang, Justin M. Drake
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B047.
https://doi.org/10.1158/1538-7445.PRCA2023-B047
Published: 02 June 2023
View articletitled, Abstract B047: Characterizing the landscape of extracellular vesicles from prostate cancer cell lines
Journal Articles

Abstract A005: Androgen receptor variants mRNA absolute quantification in prostate cancer cell models

Free
Gabrianne Larson, Zoi Sychev, Stephen Plymate, Eva Corey, Justin M. Drake
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): A005.
https://doi.org/10.1158/1538-7445.PRCA2023-A005
Published: 02 June 2023
View articletitled, Abstract A005: Androgen receptor variants mRNA absolute quantification in prostate cancer cell models
Journal Articles

Abstract B072: Induction of PARP7 creates a vulnerability for growth inhibition by RBN2397 in prostate cancer cells

Free
Chunsong Yang, Krzysztof Wierbilowicz, Natalia M. Dworak, Song Yi Bae, Sachi B. Tengse, Nicki Abianeh, Justin M. Drake, Tarek Abbas, Aakrosh Ratan, David Wotton, Bryce M. Paschal
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B072.
https://doi.org/10.1158/1538-7445.PRCA2023-B072
Published: 02 June 2023
View articletitled, Abstract B072: Induction of PARP7 creates a vulnerability for growth inhibition by RBN2397 in prostate cancer cells
Journal Articles

Abstract B045: Single cell proteomics as a method to analyze circulating tumor cells in prostate cancer patients

Free
Alec Horrmann, Zoi Sychev, Justin M. Drake
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B045.
https://doi.org/10.1158/1538-7445.PRCA2023-B045
Published: 02 June 2023
View articletitled, Abstract B045: Single cell proteomics as a method to analyze circulating tumor cells in prostate cancer patients
Journal Articles

Abstract B057: ZBTB7A as a novel vulnerability in neuroendocrine prostate cancer

Free
Song Yi Bae, Hannah E. Bergom, Abderrahman Day, Joseph T. Greene, Tanya S. Freedman, Justin H. Hwang, Justin M. Drake
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B057.
https://doi.org/10.1158/1538-7445.PRCA2023-B057
Published: 02 June 2023
View articletitled, Abstract B057: ZBTB7A as a novel vulnerability in neuroendocrine prostate cancer
Journal Articles

Abstract PR013: Unlocking the proteome of metastatic prostate cancer circulating tumor cells

Free
Justin M. Drake, Zoi Sychev, Alec Horrmann, Kaylee Judith Smith, Catalina Galeano-Garces, Ali Arafa, Nicholas Heller, Mahdi Ahmadi, Jiarong Hong, Megan Ludwig, Justin Hwang, Emmanuel S. Antonarakis, Jayant Parthasarathy
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): PR013.
https://doi.org/10.1158/1538-7445.PRCA2023-PR013
Published: 02 June 2023
View articletitled, Abstract PR013: Unlocking the proteome of metastatic prostate cancer circulating tumor cells
Journal Articles

Abstract 2405: Delineating molecular vulnerabilities of ATM mutant prostate cancers

Free
Mia Hofstad, Lan Yu, Andrea Woods, Zoi Sychev, Collin Gilbreath, Xiaofang Huo, Ralf Kittler, Justin M. Drake, Ganesh V. Raj
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2405.
https://doi.org/10.1158/1538-7445.AM2023-2405
Published: 04 April 2023
View articletitled, Abstract 2405: Delineating molecular vulnerabilities of ATM mutant prostate cancers
Journal Articles

Abstract 2309: Unlocking the proteome of metastatic prostate cancer circulating tumor cells

Free
Justin M. Drake, Zoi Sychev, Alec Horrmann, Kaylee J. Smith, Catalina Galeano-Garces, Ali Arafa, Nicholas Heller, Mahdi Ahmadi, Jiarong Hong, Megan Ludwig, Justin Hwang, Emmanuel S. Antonarakis, Jayant Parthasarathy
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2309.
https://doi.org/10.1158/1538-7445.AM2023-2309
Published: 04 April 2023
View articletitled, Abstract 2309: Unlocking the proteome of metastatic prostate cancer circulating tumor cells
Journal Articles

Abstract 191: CTC-derived organoids from liver and pancreatic cancer patients for personalized therapy

Free
Catalina Galeano-Garces, Kaylee J. Smith, Nicholas Heller, Mahdi Ahmadi, Jiarong Hong, Jayant Parthasarathy, Justin M. Drake
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 191.
https://doi.org/10.1158/1538-7445.AM2023-191
Published: 04 April 2023
View articletitled, Abstract 191: CTC-derived organoids from liver and pancreatic cancer patients for personalized therapy
Journal Articles

Abstract A043: Bypass kinase pathways lead to acquired CDK4/6 inhibitor resistance in prostate cancer

Free
Renee de Leeuw, Christopher M. McNair, Matthew J. Schiewer, Neermala P. Neupane, Michael A. Augello, Zhen Li, Larry Cheng, Akihiro Yoshida, J. Alan Diehl, E Starr Hazard, Sean M. McCourtney, Gary Hardiman, Maha H. Hussain, Justin M. Drake, Wm. Kevin Kelly, Karen E. Knudsen
Journal: Cancer Research
Cancer Res (2018) 78 (16_Supplement): A043.
https://doi.org/10.1158/1538-7445.PRCA2017-A043
Published: 14 August 2018
View articletitled, Abstract A043: Bypass kinase pathways lead to acquired CDK4/6 inhibitor resistance in prostate cancer
Journal Articles

Abstract 3882: Patient-specific druggable networks in lethal prostate cancer through proteome-guided multi-omic integration

Free
Justin M. Drake, Evan O. Paull, Nicholas A. Graham, John K. Lee, Bryan A. Smith, Tanya Stoyanova, Claire M. Faltermeier, Daniel E. Carlin, Ajay Vashisht, Jiaoti Huang, James A. Wohlschlegel, Thomas G. Graeber, Owen N. Witte, Joshua M. Stuart
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3882.
https://doi.org/10.1158/1538-7445.AM2016-3882
Published: 15 July 2016
View articletitled, Abstract 3882: Patient-specific druggable networks in lethal prostate cancer through proteome-guided multi-omic integration
Journal Articles

Abstract 1860: DNA-PK-mediated transcriptional regulation drives tumor progression and metastasis

Free
Jonathan F. Goodwin, Vishal Kothari, Justin M. Drake, Shuang Zhao, Emanuela Dylgjeri, Jeffry L. Dean, Matthew J. Schiewer, Christopher McNair, Michael S. Magee, Robert B. Den, Ziqi Zhu, Nicholas A. Graham, Ajay A. Vashisht, James A. Wohlschlegel, Thomas G. Graeber, R Jeffrey Karnes, Mandeep Takhar, Elai Davicioni, Scott A. Tomlins, Nima Sharifi, Owen N. Witte, Felix Y. Feng, Karen E. Knudsen
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1860.
https://doi.org/10.1158/1538-7445.AM2015-1860
Published: 01 August 2015
View articletitled, Abstract 1860: DNA-PK-mediated transcriptional regulation drives tumor progression and metastasis