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Journal Articles

Abstract 429: Targeting translesion synthesis to sensitize ovarian cancer cells to PARP inhibitor treatment

Na Li, Qianyun Ge, Yajing Yang, Linzhou Wang, Xiaoli Zhang, Junran Zhang, Zaibo Li, Floor Backes, Qi-En Wang

Cancer Res (2025) 85 (8_Supplement_1): 429.

https://doi.org/10.1158/1538-7445.AM2025-429

Published: 21 April 2025

View articletitled, Abstract 429: Targeting translesion synthesis to sensitize ovarian cancer cells to PARP inhibitor treatment

Journal Articles

Abstract B024: The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity

Chandra Bhushan Prasad, Adrian Oo, Zhaojun Qiu, Na Li, Deepika Singh, Xiwen Xin, Young-Jae Cho, Zaibo Li, Xiaoli Zhang, Chunhong Yan, Qingfei Zheng, Jimin Shao, Qi-En Wang, Baek Kim, Junran Zhang

Cancer Res (2024) 84 (1_Supplement): B024.

https://doi.org/10.1158/1538-7445.DNAREPAIR24-B024

Published: 09 January 2024

View articletitled, Abstract B024: The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity

Journal Articles

Abstract 6556: A gene signature of DNA damage response pathway is predictive of patient clinical outcomes and is associated with tumor immune microenvironment of lung adenocarcinoma

Xiaoli Zhang, Junran Zhang

Cancer Res (2023) 83 (7_Supplement): 6556.

https://doi.org/10.1158/1538-7445.AM2023-6556

Published: 04 April 2023

View articletitled, Abstract 6556: A gene signature of DNA damage response pathway is predictive of patient clinical outcomes and is associated with tumor immune microenvironment of lung adenocarcinoma

Journal Articles

Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy Efficacy

Cancer Res (2022) 82 (7): 1298–1312.

https://doi.org/10.1158/0008-5472.CAN-21-2229

Published: 01 April 2022

View articletitled, Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy Efficacy

Includes: Supplementary data

Journal Articles

A Genome-Wide Pooled shRNA Screen Identifies PPP2R2A as a Predictive Biomarker for the Response to ATR and CHK1 Inhibitors

Zhaojun Qiu, Pengyan Fa, Tao Liu, Chandra B. Prasad, Shanhuai Ma, Zhipeng Hong, Ernest R. Chan, Hongbing Wang, Zaibo Li, Kai He, Qi-En Wang, Terence M. Williams, Chunhong Yan, Steven T. Sizemore, Goutham Narla, Junran Zhang

Cancer Res (2020) 80 (16): 3305–3318.

https://doi.org/10.1158/0008-5472.CAN-20-0057

Published: 14 August 2020

View articletitled, A Genome-Wide Pooled shRNA Screen Identifies PPP2R2A as a Predictive Biomarker for the Response to ATR and CHK1 Inhibitors

Includes: Supplementary data

Journal Articles

Abstract 169: Drug resistance gene expression pathways in primary refractory breast cancer

Charlene Kan, Shikha Parsai, Stefanie Avril, Janice Lyons, Hannah Gilmore, Junran Zhang, Lyndsay Harris

Cancer Res (2016) 76 (14_Supplement): 169.

https://doi.org/10.1158/1538-7445.AM2016-169

Published: 15 July 2016

View articletitled, Abstract 169: Drug resistance gene expression pathways in primary refractory breast cancer

Journal Articles

Abstract 3013: RNF126 promotes homologous recombination via regulating E2F1-mediated BRCA1 expression

Ying Wang, Ou Deng, Zhihui Feng, Zhanwen Du, Xiahui Xiong, Ceshi Chen, Zhefu Ma, Junran Zhang

Cancer Res (2015) 75 (15_Supplement): 3013.

https://doi.org/10.1158/1538-7445.AM2015-3013

Published: 01 August 2015

View articletitled, Abstract 3013: RNF126 promotes homologous recombination via regulating E2F1-mediated BRCA1 expression

Journal Articles

The Polyamine Catabolic Enzyme SAT1 Modulates Tumorigenesis and Radiation Response in GBM

Adina Brett-Morris, Bradley M. Wright, Yuji Seo, Vinay Pasupuleti, Junran Zhang, Jun Lu, Raffaella Spina, Eli E. Bar, Maneesh Gujrati, Rebecca Schur, Zheng-Rong Lu, Scott M. Welford

Cancer Res (2014) 74 (23): 6925–6934.

https://doi.org/10.1158/0008-5472.CAN-14-1249

Published: 30 November 2014

View articletitled, The Polyamine Catabolic Enzyme SAT1 Modulates Tumorigenesis and Radiation Response in GBM

Includes: Supplementary data

Journal Articles

Abstract 3954: SAT1 (Spermidine/spermine-N1-acetyltrasferase 1) promotes radiation resistance in glioblastoma multiforme

Adina Brett-Morris, Scott M. Welford, Eli Bar, Raffaella Spina, Bradley Wright, Junran Zhang, Jun Lu, Yuji Seo

Cancer Res (2014) 74 (19_Supplement): 3954.

https://doi.org/10.1158/1538-7445.AM2014-3954

Published: 01 October 2014

View articletitled, Abstract 3954: SAT1 (Spermidine/spermine-N1-acetyltrasferase 1) promotes radiation resistance in glioblastoma multiforme

Journal Articles

BRCA1- and BRCA2-Deficient Cells Are Sensitive to Etoposide-Induced DNA Double-Strand Breaks via Topoisomerase II

Alejandro D. Treszezamsky, Lisa A. Kachnic, Zhihui Feng, Junran Zhang, Chake Tokadjian, Simon N. Powell

Cancer Res (2007) 67 (15): 7078–7081.

https://doi.org/10.1158/0008-5472.CAN-07-0601

Published: 01 August 2007

View articletitled, BRCA1- and BRCA2-Deficient Cells Are Sensitive to Etoposide-Induced DNA Double-Strand Breaks via Topoisomerase II

Journal Articles

Checkpoint Kinase 2–Mediated Phosphorylation of BRCA1 Regulates the Fidelity of Nonhomologous End-Joining

Jing Zhuang, Junran Zhang, Henning Willers, Hong Wang, Jay H. Chung, Dik C. van Gent, Dennis E. Hallahan, Simon N. Powell, Fen Xia

Cancer Res (2006) 66 (3): 1401–1408.

https://doi.org/10.1158/0008-5472.CAN-05-3278

Published: 01 February 2006

View articletitled, Checkpoint Kinase 2–Mediated Phosphorylation of BRCA1 Regulates the Fidelity of Nonhomologous End-Joining

Journal Articles

Insulin receptor substrate-1 functions in mammary tumor metastasis

Zhefu Ma, Junran Zhang, Maura A. Byrne, Leslie M. Shaw

Cancer Res (2005) 65 (9_Supplement): 1246–1247.

Published: 01 May 2005

View articletitled, Insulin receptor substrate-1 functions in mammary tumor metastasis

Journal Articles

Role of MDC1 in homologous recombination

Junran Zhang, Zhefu Ma, Alejandro Treszezamsky, Simon N. Powell

Cancer Res (2005) 65 (9_Supplement): 380–381.

Published: 01 May 2005

View articletitled, Role of MDC1 in homologous recombination

Journal Articles

DNA double strand break repair of blunt ends is regulated by phosphorylation of serine-988 in BRCA1

Junran Zhang, Fen Xia, Simon N. Powell

Cancer Res (2004) 64 (7_Supplement): 613.

Published: 01 April 2004

View articletitled, DNA double strand break repair of blunt ends is regulated by phosphorylation of serine-988 in BRCA1

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Abstract 429: Targeting translesion synthesis to sensitize ovarian cancer cells to PARP inhibitor treatment

Abstract B024: The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity

Abstract 6556: A gene signature of DNA damage response pathway is predictive of patient clinical outcomes and is associated with tumor immune microenvironment of lung adenocarcinoma

Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy Efficacy

A Genome-Wide Pooled shRNA Screen Identifies PPP2R2A as a Predictive Biomarker for the Response to ATR and CHK1 Inhibitors

Abstract 169: Drug resistance gene expression pathways in primary refractory breast cancer

Abstract 3013: RNF126 promotes homologous recombination via regulating E2F1-mediated BRCA1 expression

The Polyamine Catabolic Enzyme SAT1 Modulates Tumorigenesis and Radiation Response in GBM

Abstract 3954: SAT1 (Spermidine/spermine-N1-acetyltrasferase 1) promotes radiation resistance in glioblastoma multiforme

BRCA1- and BRCA2-Deficient Cells Are Sensitive to Etoposide-Induced DNA Double-Strand Breaks via Topoisomerase II

Checkpoint Kinase 2–Mediated Phosphorylation of BRCA1 Regulates the Fidelity of Nonhomologous End-Joining

Insulin receptor substrate-1 functions in mammary tumor metastasis

Role of MDC1 in homologous recombination

DNA double strand break repair of blunt ends is regulated by phosphorylation of serine-988 in BRCA1

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