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Jung-Hyun Shim
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Journal Articles

Abstract 2959: Deoxysappanchalcone inhibits cell growth by regulation of TOPK signaling pathway in colon cancer

Ran Zhao, Hai Huang, Bu Young Choi, Mengqiu Song, Fanxiang Yin, Xiaorong Fu, Hanyong Chen, Jung Hyun Shim, Mee-Hyun Lee, Zigang Dong
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2959.
https://doi.org/10.1158/1538-7445.AM2019-2959
Published: 01 July 2019
View article titled, Abstract 2959: Deoxysappanchalcone inhibits cell growth by regulation of TOPK signaling pathway in colon cancer
Journal Articles

Abstract 1718: Down-regulation of p16INK4a by hYSK1 promotes cancer cell migration under hypoxic conditions

Mee-Hyun Lee, Jung-Hyun Shim, Zigang Dong, Young-Joon Surh, Bu Young Choi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1718.
https://doi.org/10.1158/1538-7445.AM2019-1718
Published: 01 July 2019
View article titled, Abstract 1718: Down-regulation of p16<sup>INK4a</sup> by hYSK1 promotes cancer cell migration under hypoxic conditions
Journal Articles

Abstract 5450: Anticancer effects of picrasidine Q from Angelica keiski on esophageal squamous cell carcinoma by downregulation of FGFR2 signaling pathways

Xuejiao Liu, Yuanyuan Shi, Mengqiu Song, Ran Zhao, Hanyong Chen, Jung Hyun Shim, Zigang Dong, Mee-Hyun Lee
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5450.
https://doi.org/10.1158/1538-7445.AM2018-5450
Published: 01 July 2018
View article titled, Abstract 5450: Anticancer effects of picrasidine Q from <em>Angelica keiski</em> on esophageal squamous cell carcinoma by downregulation of FGFR2 signaling pathways
Journal Articles

Abstract 2021: Ablation of caspase-7 promotes solar-simulated light-induced mouse skin carcinogenesis through upregulation of keratin-17

Mee-Hyun Lee, Do Young Lim, Sung Young Lee, Jung Hyun Shim, Xuejiao Liu, Ran Zhao, Hai Huang, G.Timothy Bowden, Young-Joon Surh, Yong-Yeon Cho, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2021.
https://doi.org/10.1158/1538-7445.AM2017-2021
Published: 01 July 2017
View article titled, Abstract 2021: Ablation of caspase-7 promotes solar-simulated light-induced mouse skin carcinogenesis through upregulation of keratin-17
Journal Articles

Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity

Dong Joon Kim, Eunmiri Roh, Mee-Hyun Lee, Naomi Oi, Do Young Lim, Myoung Ok Kim, Yong-Yeon Cho, Angelo Pugliese, Jung-Hyun Shim, Hanyong Chen, Eun Jin Cho, Jong-Eun Kim, Sun Chul Kang, Souren Paul, Hee Eun Kang, Ji Won Jung, Sung-Young Lee, Sung-Hyun Kim, Kanamata Reddy, Young Il Yeom, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2016) 76 (5): 1146–1157.
https://doi.org/10.1158/0008-5472.CAN-15-0442
Published: 29 February 2016
View article titled, Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity
Open the PDF for Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity in another window
Includes: Supplementary data
Journal Articles

Abstract 1080: Computational and biochemical discovery of RSK2 as a novel target for epigallocatechin gallate (EGCG)

Hanyong Chen, Ke Yao, Xiaoyu Chang, Jung-Hyun Shim, Hong-Gyum Kim, Margarita Malakhova, Dong-Joon Kim, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1080.
https://doi.org/10.1158/1538-7445.AM2015-1080
Published: 01 August 2015
View article titled, Abstract 1080: Computational and biochemical discovery of RSK2 as a novel target for epigallocatechin gallate (EGCG)
Journal Articles

Abstract 2235: Epigallocatechin-gallate suppresses tumorigenesis by directly targeting Pin1.

Darya V. Urusova, Jung-Hyun Shim, Dong Joon Kim, Sung Keun Jung, Tatyana Zykova, Andria Carper, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2235.
https://doi.org/10.1158/1538-7445.AM2013-2235
Published: 15 April 2013
View article titled, Abstract 2235: Epigallocatechin-gallate suppresses tumorigenesis by directly targeting Pin1.
Journal Articles

Abstract 4509: Epigallocatechin gallate suppresses tumorigenesis of lung cancer cells by targeting Ras-GTPase-activating protein SH3-domain binding protein 1

Jung-Hyun Shim, Zheng-Yuan Su, Jung-II Chae, Dong-Joon Kim, Feng Zhu, Wei-Ya Ma, Ann M. Bode, Chung S. Yang, Nam-Pyo Cho, Zigang Dong
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4509.
https://doi.org/10.1158/1538-7445.AM10-4509
Published: 15 April 2010
View article titled, Abstract 4509: Epigallocatechin gallate suppresses tumorigenesis of lung cancer cells by targeting Ras-GTPase-activating protein SH3-domain binding protein 1
Journal Articles

Abstract 224: Antitumorigenic effect of synthetic C-substituted diindolyl methanes originating from cruciferous vegetables in KB human oral cancer cells through endoplasmic reticulum stress

Eun-Sun Choi, Jung-Hyun Shim, Sung-Dae Cho, Nam-Pyo Cho
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 224.
https://doi.org/10.1158/1538-7445.AM10-224
Published: 15 April 2010
View article titled, Abstract 224: Antitumorigenic effect of synthetic C-substituted diindolyl methanes originating from cruciferous vegetables in KB human oral cancer cells through endoplasmic reticulum stress
Journal Articles

Abstract 223: Apoptotic activity of Polygonum cuspidatum in KB human oral cancer cells through the downregulation of specificity protein 1

Ji-Ae Shin, Jung-Hyun Shim, Jae-Gyu Jeon, Sung-Dae Cho
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 223.
https://doi.org/10.1158/1538-7445.AM10-223
Published: 15 April 2010
View article titled, Abstract 223: Apoptotic activity of <em>Polygonum cuspidatum</em> in KB human oral cancer cells through the downregulation of specificity protein 1
Journal Articles

Abstract 2669: Crystal structure of the active N-terminal kinase domain of p90 ribosomal S6 protein kinase 2

Margarita Malakhova, Igor Kurinov, Kangdong Liu, Duo Zheng, Jung-Hyun Shim, Ann Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2669.
https://doi.org/10.1158/1538-7445.AM10-2669
Published: 15 April 2010
View article titled, Abstract 2669: Crystal structure of the active N-terminal kinase domain of p90 ribosomal S6 protein kinase 2
Journal Articles

[6]-Gingerol Suppresses Colon Cancer Growth by Targeting Leukotriene A4 Hydrolase

Chul-Ho Jeong, Ann M. Bode, Angelo Pugliese, Yong-Yeon Cho, Hong-Gyum Kim, Jung-Hyun Shim, Young-Jin Jeon, Honglin Li, Hualiang Jiang, Zigang Dong
Journal: Cancer Research
Cancer Res (2009) 69 (13): 5584–5591.
https://doi.org/10.1158/0008-5472.CAN-09-0491
Published: 01 July 2009
View article titled, [6]-Gingerol Suppresses Colon Cancer Growth by Targeting Leukotriene A<sub>4</sub> Hydrolase
Open the PDF for [6]-Gingerol Suppresses Colon Cancer Growth by Targeting Leukotriene A<sub>4</sub> Hydrolase in another window
Includes: Supplementary data
Journal Articles

Abstract #2461: Modeling of the interaction between EGCG and two separate kinase domains of RSK2

Angelo Pugliese, Jung-Hyun Shim, Margarita Malakhova, Ann Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2461.
Published: 01 May 2009
View article titled, Abstract #2461: Modeling of the interaction between EGCG and two separate kinase domains of RSK2
Journal Articles

Abstract #4104: JNK1 phosphorylates Myt1 to prevent UVA-induced skin cancer

Hong Seok Choi, Ann M Bode, Jung-Hyun Shim, Sung-Young Lee, Zigang Dong
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4104.
Published: 01 May 2009
View article titled, Abstract #4104: JNK1 phosphorylates Myt1 to prevent UVA-induced skin cancer
Journal Articles

The C-terminal kinase domain of RSK2 interacts with ERK1 in vitro.

Margarita Malakhova, Valentina Tereshko, Jung-Hyun Shim
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3187.
Published: 01 May 2008
View article titled, The C-terminal kinase domain of RSK2 interacts with ERK1 <em>in vitro</em>.
Journal Articles

EGCG suppresses CD3-mediated T-cell-induced pathways in leukemia cells via Zap-70 inhibition

Jung-Hyun Shim, Hong Seok Choi, Angelo Pugliese, Bu Young Choi, Ann Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2344.
Published: 01 May 2008
View article titled, EGCG suppresses CD3-mediated T-cell-induced pathways in leukemia cells via Zap-70 inhibition