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Journal Articles

Abstract LB168: A selective, potent, and orally bioavailable CDK7 inhibitor demonstrates superior anti-cancer activity in colorectal cancer models

Heuijoon Park, Kyoungwan Seo, Jihyun Yu, Jieun Kim, Min Sung Joo, Sungeun Kim, Joonhyung Lee, Jeonghyeon Lee, Eun-Jung Kim, Joonwoo Nam, Wooseok Han
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB168.
https://doi.org/10.1158/1538-7445.AM2024-LB168
Published: 05 April 2024
View article titled, Abstract LB168: A selective, potent, and orally bioavailable CDK7 inhibitor demonstrates superior anti-cancer activity in colorectal cancer models
Journal Articles

Abstract 2241: Healthcare underutilization, healthcare mistrust, and quality of life among cancer survivors who use cannabis

Sunny Jung Kim, Ghader Dargahi Abbasabad, Viktor Clark, Susan Hong, Vanessa B. Sheppard
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2241.
https://doi.org/10.1158/1538-7445.AM2024-2241
Published: 22 March 2024
View article titled, Abstract 2241: Healthcare underutilization, healthcare mistrust, and quality of life among cancer survivors who use cannabis
Journal Articles

Abstract 3127: Development of three-dimensional cancer cell line spheroid models for the in vitro functional characterization of cytotoxic antibody-drug conjugates

Jodi Wong, Andrea Hernández Rojas, Allysha Bissessur, Lemlem T. Degefie, Araba P. Sagoe-Wagner, Samir Das, Vincent Fung, Kevin Yin, Renee Duan, Sam Lawn, Laurence Madera, Catrina Mi Jung Kim, Alex Wu, Mark E. Petersen, Raffaele Colombo, Jamie R. Rich, Stuart D. Barnscher
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3127.
https://doi.org/10.1158/1538-7445.AM2024-3127
Published: 22 March 2024
View article titled, Abstract 3127: Development of three-dimensional cancer cell line spheroid models for the <em>in vitro</em> functional characterization of cytotoxic antibody-drug conjugates
Journal Articles

Abstract 2804: Comparative analysis of microbial diversity and abundance in colorectal cancer patients before and after surgery

Hyeree Park, Min Jung Kim, Ji Won Park, Seung-Yong Jeong, Aesun Shin, Sung-Yup Cho, Eun Sung Jung, Dong Ho Suh, Sunyoung Lee, Yu Jin Park
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2804.
https://doi.org/10.1158/1538-7445.AM2024-2804
Published: 22 March 2024
View article titled, Abstract 2804: Comparative analysis of microbial diversity and abundance in colorectal cancer patients before and after surgery
Journal Articles

Abstract 2196: Susceptibility to tobacco use among rural adolescents: Examining the role of tobacco marketing exposure and media use intensity

Sunny Jung Kim, Kendall Fugate-Laus, Jeremy Barsell, Elizabeth K. Do, Rashelle Hayes, David Wheeler, Bernard Fuemmeler
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2196.
https://doi.org/10.1158/1538-7445.AM2024-2196
Published: 22 March 2024
View article titled, Abstract 2196: Susceptibility to tobacco use among rural adolescents: Examining the role of tobacco marketing exposure and media use intensity
Journal Articles

Abstract 7319: Glycemic traits and colorectal cancer survival in a cohort of South Korean patients: A Mendelian randomization analysis

So Yon Jun, Sooyoung Cho, Min Jung Kim, Ji Won Park, Seung Yong Jeong, Aesun Shin
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7319.
https://doi.org/10.1158/1538-7445.AM2024-7319
Published: 22 March 2024
View article titled, Abstract 7319: Glycemic traits and colorectal cancer survival in a cohort of South Korean patients: A Mendelian randomization analysis
Journal Articles

Abstract 1967: IN-119873, the next-generation allosteric EGFR TKI, a potent and highly selective EGFR L858R for the treatment of osimertinib-resistant NSCLC

Jong Ryoul Choi, Daseul Yoon, Seo Hyun Kim, Do Gyeong Kim, Seock Yong Kang, Seong-Il Choi, Somyi Park, Hyun Kyung Lee, Donghyun Kim, Ju Hyun Lee, Hye-Jung Kim, Bong Tae Kim
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1967.
https://doi.org/10.1158/1538-7445.AM2024-1967
Published: 22 March 2024
View article titled, Abstract 1967: IN-119873, the next-generation allosteric EGFR TKI, a potent and highly selective EGFR L858R for the treatment of osimertinib-resistant NSCLC
Journal Articles

Abstract 1822: Artemisia annua Lpolyphenols augment b-lapachone effects on oxaliplatin-resistant HCT 116 colorectal cancer cells by downregulating TERT, CD44, EGFR and oxaliplatin resistance-related proteins of OXP-R-Hct 116 cells

Won Sup Lee, Eun Joo Jung, Hye Jung Kim, Sung Chul Shin, Gon Sup Kim, Jin-Myung Jung, Soon Chan Hong, Choong Won Kim
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1822.
https://doi.org/10.1158/1538-7445.AM2024-1822
Published: 22 March 2024
View article titled, Abstract 1822: <em>Artemisia annua L</em>polyphenols augment b-lapachone effects on oxaliplatin-resistant HCT 116 colorectal cancer cells by downregulating TERT, CD44, EGFR and oxaliplatin resistance-related proteins of OXP-R-Hct 116 cells
Journal Articles

Abstract 380: Co-downregulation of GRP78 and ATR enhances apoptosis in pancreatic ductal adenocarcinoma

Su In Lee, Ah-Rong Nam, Kyoung-Seok Oh, Jae-Min Kim, Ju-Hee Bang, Yoojin Jeong, Sea Young Choo, Hyo Jung Kim, Jeesun Yoon, Tae-Yong Kim, Do-Youn Oh
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 380.
https://doi.org/10.1158/1538-7445.AM2024-380
Published: 22 March 2024
View article titled, Abstract 380: Co-downregulation of GRP78 and ATR enhances apoptosis in pancreatic ductal adenocarcinoma
Journal Articles

Abstract 2425: Pairwise analysis of plasma cell-free DNA before and after paclitaxel plus ramucirumab treatment in patients with metastatic gastric cancer

Ji-Won Kim, Dong Soo Kyung, Won Yeong Ko, Hwang-Phill Kim, Sung-Hyun Hwang, Kui-Jin Kim, Ju Hyun Lee, Jeongmin Seo, Minsu Kang, Eun Hee Jung, Koung Jin Suh, Se Hyun Kim, Jin Won Kim, Yu Jung Kim, Jee Hyun Kim, Keun-Wook Lee
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2425.
https://doi.org/10.1158/1538-7445.AM2024-2425
Published: 22 March 2024
View article titled, Abstract 2425: Pairwise analysis of plasma cell-free DNA before and after paclitaxel plus ramucirumab treatment in patients with metastatic gastric cancer
Journal Articles

Abstract 3327: L-pampo™, a TLR2/3 agonist, enhances anti-tumor immune responses and synergistically improves the anti-tumor efficacy of immune checkpoint inhibitors in cold tumors

Guentae Kim, Yoonki Heo, Hye Jung Kim, Sejung Park, Byung Cheol Ahn, Won Suk Lee, Chan Kim, Hong Jae Chon, Eunyoung Chun, Jung Sun Yum
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3327.
https://doi.org/10.1158/1538-7445.AM2024-3327
Published: 22 March 2024
View article titled, Abstract 3327: L-pampo™, a TLR2/3 agonist, enhances anti-tumor immune responses and synergistically improves the anti-tumor efficacy of immune checkpoint inhibitors in cold tumors
Journal Articles

Abstract 3313: Discovery of a potent, selective, and orally available small molecule for disruption of the SOS1-RAS interaction

Dong Hyuk Ki, Hana Yu, Donggeon Kim, Yeejin Jeon, Seongin Jo, Joonwoo Nam, Eun-Jung Kim, Sungeun Kim, Hunmi Choi, Jieun Kim, Jihyun Yu, Sungpil Choi, Wooseok Han
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3313.
https://doi.org/10.1158/1538-7445.AM2024-3313
Published: 22 March 2024
View article titled, Abstract 3313: Discovery of a potent, selective, and orally available small molecule for disruption of the SOS1-RAS interaction
Journal Articles

Abstract 3295: Pharmacological characterization of CYRS1542: A potent and orally available GSPT1 molecular glue degrader for the treatment of neuroendocrine solid cancer with a favorable safety profile

Min Sung Joo, JaeYung Lee, Joonhyung Lee, Eun-Jung Kim, Seogbeom Song, Jeonghyeon Lee, Joonwoo Nam, Heuijoon Park, Jaewoo Park, Keon Wook Kang, Wooseok Han
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3295.
https://doi.org/10.1158/1538-7445.AM2024-3295
Published: 22 March 2024
View article titled, Abstract 3295: Pharmacological characterization of CYRS1542: A potent and orally available GSPT1 molecular glue degrader for the treatment of neuroendocrine solid cancer with a favorable safety profile
Journal Articles

Abstract 966: Longitudinal comparative analysis of circulating tumor DNA and matched tumor tissue DNA in patients with metastatic colorectal cancer receiving palliative first-line systemic anti-cancer therapy

Ji-Won Kim, Seung-been Lee, Hong-Geun Kim, Sung-Hyun Hwang, Kui-Jin Kim, Ju Hyun Lee, Jeongmin Seo, Minsu Kang, Eun Hee Jung, Koung Jin Suh, Se Hyun Kim, Jin Won Kim, Yu Jung Kim, Jee Hyun Kim, Nak-Jung Kwon, Keun-Wook Lee
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 966.
https://doi.org/10.1158/1538-7445.AM2024-966
Published: 22 March 2024
View article titled, Abstract 966: Longitudinal comparative analysis of circulating tumor DNA and matched tumor tissue DNA in patients with metastatic colorectal cancer receiving palliative first-line systemic anti-cancer therapy
Journal Articles

Abstract 390: Direct interaction of Pin1 with HIF-prolyl hydroxylase 2: Implications for breast cancer cell growth and survival

Yanymee Nimesia Guillen Quispe, Su-Jung Kim, Soma Saeidi, Gyo-Jin Choi, Chaithanya Chelakkot, Tianchi Zhou, Sang-Beom Bang, Tae-Won Kim, Young-Kee Shin, Young-Joon Surh
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 390.
https://doi.org/10.1158/1538-7445.AM2024-390
Published: 22 March 2024
View article titled, Abstract 390: Direct interaction of Pin1 with HIF-prolyl hydroxylase 2: Implications for breast cancer cell growth and survival
Journal Articles

Abstract 2599: Trastuzumab deruxtecan reprograms immune response by stimulating cGAS-STING pathway in gastric cancer cells

Kyoung-Seok Oh, Ah-Rong Nam, Ju-Hee Bang, Yoojin Jeong, Sea Young Choo, Hyo Jung Kim, Su In Lee, Jae-Min Kim, Jeesun Yoon, Tae-Yong Kim, Do-Youn Oh
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2599.
https://doi.org/10.1158/1538-7445.AM2024-2599
Published: 22 March 2024
View article titled, Abstract 2599: Trastuzumab deruxtecan reprograms immune response by stimulating cGAS-STING pathway in gastric cancer cells
Journal Articles

Abstract 5711: Anti-tumor effects of fadraciclib, CDK2/9 inhibitor, in biliary tract cancer

Jae-Min Kim, Ah-Rong Nam, Kyoung-Seok Oh, Ju-Hee Bang, Yoojin Jeong, Sea Young Choo, Su In Lee, Hyo Jung Kim, Jeesun Yoon, Tae-Yong Kim, Do-Youn Oh
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5711.
https://doi.org/10.1158/1538-7445.AM2024-5711
Published: 22 March 2024
View article titled, Abstract 5711: Anti-tumor effects of fadraciclib, CDK2/9 inhibitor, in biliary tract cancer
Journal Articles

Abstract 5006: Discovery of novel heterobifunctional degraders of mutant EGFR proteins for NSCLCs harboring various EGFR mutations

Dong Hyuk Ki, Min Sung Joo, Joonwoo Nam, Hunmi Choi, Kyoungwan Seo, Eun-Jung Kim, Jiyeon Kim, Chulwon Kim, Jimmy Taiguang Jin, Wooseok Han
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5006.
https://doi.org/10.1158/1538-7445.AM2023-5006
Published: 04 April 2023
View article titled, Abstract 5006: Discovery of novel heterobifunctional degraders of mutant EGFR proteins for NSCLCs harboring various EGFR mutations
Journal Articles

Abstract 1673: Discovery of potent, selective, and orally bioavailable GSPT1 degraders and their pre-clinical anti-tumor activity in acute myeloid leukemia and solid tumors

Min Sung Joo, JaeYung Lee, Eun-Jung Kim, Dong Hyuk Ki, Hunmi Choi, Joonwoo Nam, Jaewoo Park, Keon Wook Kang, Wooseok Han
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1673.
https://doi.org/10.1158/1538-7445.AM2023-1673
Published: 04 April 2023
View article titled, Abstract 1673: Discovery of potent, selective, and orally bioavailable GSPT1 degraders and their pre-clinical anti-tumor activity in acute myeloid leukemia and solid tumors
Journal Articles

Abstract 5892: Microbial diversity and composition according to short-term postoperative complication status in colorectal cancer patients

Hyeree Park, Tung Hoang, Min Jung Kim, Ji Won Park, Seung-Yong Jeong, Aesun Shin
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5892.
https://doi.org/10.1158/1538-7445.AM2023-5892
Published: 04 April 2023
View article titled, Abstract 5892: Microbial diversity and composition according to short-term postoperative complication status in colorectal cancer patients