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Journal Articles

Abstract 5791: Autophagy & PIM1 kinase inhibition in breast cancer stem cells & bulk cancer cells attenuates breast cancer & metastasis

Kanakaraju Manupati, Mingang Hao, Michael Haas, Syn Kok Yeo, Jun-Lin Guan

Cancer Res (2023) 83 (7_Supplement): 5791.

https://doi.org/10.1158/1538-7445.AM2023-5791

Published: 04 April 2023

View article titled, Abstract 5791: Autophagy & PIM1 kinase inhibition in breast cancer stem cells & bulk cancer cells attenuates breast cancer & metastasis

Journal Articles

Abstract 2468: The role of autophagy in lymphangiosarcoma development

Fuchun Yang, Michael Haas, Jun-Lin Guan

Cancer Res (2021) 81 (13_Supplement): 2468.

https://doi.org/10.1158/1538-7445.AM2021-2468

Published: 01 July 2021

View article titled, Abstract 2468: The role of autophagy in lymphangiosarcoma development

Journal Articles

FIP200 Suppresses Immune Checkpoint Therapy Responses in Breast Cancers by Limiting AZI2/TBK1/IRF Signaling Independent of Its Canonical Autophagy Function

Takako Okamoto, Syn Kok Yeo, Mingang Hao, Mary Rose Copley, Michael A. Haas, Song Chen, Jun-Lin Guan

Cancer Res (2020) 80 (17): 3580–3592.

https://doi.org/10.1158/0008-5472.CAN-20-0519

Published: 02 September 2020

View article titled, FIP200 Suppresses Immune Checkpoint Therapy Responses in Breast Cancers by Limiting AZI2/TBK1/IRF Signaling Independent of Its Canonical Autophagy Function

Includes: Supplementary data

Journal Articles

Abstract 4267: mTORC1-dependent tumors have innate vulnerability to autophagic cell death by HDAC inhibitors

Fuchun Yang, Chenran Wang, Shaogang Sun, Michael Haas, Syn Yeo, Jun-Lin Guan

Cancer Res (2019) 79 (13_Supplement): 4267.

https://doi.org/10.1158/1538-7445.AM2019-4267

Published: 01 July 2019

View article titled, Abstract 4267: mTORC1-dependent tumors have innate vulnerability to autophagic cell death by HDAC inhibitors

Journal Articles

Abstract 1831: Role of autophagy in lymphangiosarcoma initiation and progression

Fuchun Yang, Shaogang Sun, Jun-Lin Guan

Cancer Res (2019) 79 (13_Supplement): 1831.

https://doi.org/10.1158/1538-7445.AM2019-1831

Published: 01 July 2019

View article titled, Abstract 1831: Role of autophagy in lymphangiosarcoma initiation and progression

Journal Articles

Abstract 4386: Regulation of FIP200 by Her2 and its role in Her2-driven mammary tumors

Mingang Hao, Jun-Lin Guan

Cancer Res (2018) 78 (13_Supplement): 4386.

https://doi.org/10.1158/1538-7445.AM2018-4386

Published: 01 July 2018

View article titled, Abstract 4386: Regulation of FIP200 by Her2 and its role in Her2-driven mammary tumors

Journal Articles

Abstract 1327: Autophagy facilitates tumor promotion in PyMT tumors through up-regulation of Pparg

Takako Okamoto, Song Chen, Syn Yeo, Jun-Lin Guan

Cancer Res (2018) 78 (13_Supplement): 1327.

https://doi.org/10.1158/1538-7445.AM2018-1327

Published: 01 July 2018

View article titled, Abstract 1327: Autophagy facilitates tumor promotion in PyMT tumors through up-regulation of Pparg

Journal Articles

Abstract 5882: FAK is required for the survival of tumor cells in MMTV-Wnt1 driven basal-like mammary tumors

Ritama Paul, Syn K. Yeo, Ming Luo, Susan Waltz, Jun-Lin Guan

Cancer Res (2017) 77 (13_Supplement): 5882.

https://doi.org/10.1158/1538-7445.AM2017-5882

Published: 01 July 2017

View article titled, Abstract 5882: FAK is required for the survival of tumor cells in MMTV-Wnt1 driven basal-like mammary tumors

Journal Articles

Abstract 1627: Kinase-independent function of focal adhesion kinase in lung metastasis of breast cancer

Ming Luo, Max S. Wicha, Jun-Lin Guan

Cancer Res (2016) 76 (14_Supplement): 1627.

https://doi.org/10.1158/1538-7445.AM2016-1627

Published: 15 July 2016

View article titled, Abstract 1627: Kinase-independent function of focal adhesion kinase in lung metastasis of breast cancer

Journal Articles

Abstract LB-038: Constitutive activation of mTORC1 in endothelial cells leads to the development and progression of lymphangiosarcoma through VEGF autocrine signaling

Shaogang Sun, Song Chen, Fei Liu, Haige Wu, Jonathan McHugh, Ingrid Bergin, Anita Gupta, Denise Adams, Jun-Lin Guan

Cancer Res (2016) 76 (14_Supplement): LB-038.

https://doi.org/10.1158/1538-7445.AM2016-LB-038

Published: 15 July 2016

View article titled, Abstract LB-038: Constitutive activation of mTORC1 in endothelial cells leads to the development and progression of lymphangiosarcoma through VEGF autocrine signaling

Journal Articles

Autophagy Differentially Regulates Distinct Breast Cancer Stem-like Cells in Murine Models via EGFR/Stat3 and Tgfβ/Smad Signaling

Syn Kok Yeo, Jian Wen, Song Chen, Jun-Lin Guan

Cancer Res (2016) 76 (11): 3397–3410.

https://doi.org/10.1158/0008-5472.CAN-15-2946

Published: 31 May 2016

View article titled, Autophagy Differentially Regulates Distinct Breast Cancer Stem-like Cells in Murine Models via EGFR/Stat3 and Tgfβ/Smad Signaling

Includes: Supplementary data

Journal Articles

Abstract 4228: Identification of distinct mammary cancer stem cells with differential requirements for the autophagy regulator FIP200

Syn K. Yeo, Jian Wen, Song Chen, Jun-Lin Guan

Cancer Res (2015) 75 (15_Supplement): 4228.

https://doi.org/10.1158/1538-7445.AM2015-4228

Published: 01 August 2015

View article titled, Abstract 4228: Identification of distinct mammary cancer stem cells with differential requirements for the autophagy regulator FIP200

Journal Articles

Abstract 4188: Conditional epithelial cell-specific knockout of CCN6/Wisp3 disrupts normal development of the virgin murine mammary gland

Emily E. Martin, Wei Huang, Jun-Lin Guan, Celina G. Kleer

Cancer Res (2015) 75 (15_Supplement): 4188.

https://doi.org/10.1158/1538-7445.AM2015-4188

Published: 01 August 2015

View article titled, Abstract 4188: Conditional epithelial cell-specific knockout of CCN6/Wisp3 disrupts normal development of the virgin murine mammary gland

Journal Articles

Distinct FAK Activities Determine Progenitor and Mammary Stem Cell Characteristics

Ming Luo, Xiaofeng Zhao, Song Chen, Suling Liu, Max S. Wicha, Jun-Lin Guan

Cancer Res (2013) 73 (17): 5591–5602.

https://doi.org/10.1158/0008-5472.CAN-13-1351

Published: 02 September 2013

View article titled, Distinct FAK Activities Determine Progenitor and Mammary Stem Cell Characteristics

Includes: Supplementary data

Journal Articles

Abstract SY36-04: Analysis of autophagy functions in mouse models of breast cancer

Jun-Lin Guan

Cancer Res (2012) 72 (8_Supplement): SY36-04.

https://doi.org/10.1158/1538-7445.AM2012-SY36-04

Published: 15 April 2012

View article titled, Abstract SY36-04: Analysis of autophagy functions in mouse models of breast cancer

Journal Articles

Abstract 389: Mice with kinase-dead FAK mutation in endothelial cells are protected from VEGF-induced permeability and are resistant to tumor cell metastasis

Ju-Ock Nam, Lisette M. Acevedo, Erik Goka, Xiao Lei Chen, Colin Walsh, Isabelle Tanjoni, Jun-Lin Guan, Sara M. Weis, David A. Cheresh, David D. Schlaepfer

Cancer Res (2010) 70 (8_Supplement): 389.

https://doi.org/10.1158/1538-7445.AM10-389

Published: 15 April 2010

View article titled, Abstract 389: Mice with kinase-dead FAK mutation in endothelial cells are protected from VEGF-induced permeability and are resistant to tumor cell metastasis

Journal Articles

Mammary Epithelial-Specific Ablation of the Focal Adhesion Kinase Suppresses Mammary Tumorigenesis by Affecting Mammary Cancer Stem/Progenitor Cells

Ming Luo, Huaping Fan, Tamas Nagy, Huijun Wei, Chenran Wang, Suling Liu, Max S. Wicha, Jun-Lin Guan

Cancer Res (2009) 69 (2): 466–474.

https://doi.org/10.1158/0008-5472.CAN-08-3078

Published: 15 January 2009

View article titled, Mammary Epithelial-Specific Ablation of the Focal Adhesion Kinase Suppresses Mammary Tumorigenesis by Affecting Mammary Cancer Stem/Progenitor Cells

Includes: Supplementary data

Journal Articles

Compensatory role for proline-rich tyrosine kinase 2 (Pyk2) during angiogenesis in adult mice lacking endothelial cell focal adhesion kinase (FAK)

Sara Weis, Ssang-Taek Lim, Kimberly Lutu-Fuga, Leo Barnes, Xiao Lei Chen, Joachim Goethert, Tang-Long Shen, Jun-Lin Guan, David Schlaepfer, David Cheresh

Cancer Res (2008) 68 (9_Supplement): 5846.

Published: 01 May 2008

View article titled, Compensatory role for proline-rich tyrosine kinase 2 (Pyk2) during angiogenesis in adult mice lacking endothelial cell focal adhesion kinase (FAK)

Journal Articles

Stearate inhibits breast cancer cell spreading, motility, and invasion

Arig Ibrahim Hashim, Stephanie Cowey, Manuel Pallero, Joanne Murphy-Ullrich, Chuanyu Li, Jun-Lin Guan, Gene P. Siegal, Robert W. Hardy

Cancer Res (2006) 66 (8_Supplement): 427.

Published: 15 April 2006

View article titled, Stearate inhibits breast cancer cell spreading, motility, and invasion

Journal Articles

Mechanism of Cell Cycle Regulation by FIP200 in Human Breast Cancer Cells

Zara K. Melkoumian, Xu Peng, Boyi Gan, Xiaoyang Wu, Jun-Lin Guan

Cancer Res (2005) 65 (15): 6676–6684.

https://doi.org/10.1158/0008-5472.CAN-04-4142

Published: 01 August 2005

View article titled, Mechanism of Cell Cycle Regulation by FIP200 in Human Breast Cancer Cells

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Abstract 5791: Autophagy & PIM1 kinase inhibition in breast cancer stem cells & bulk cancer cells attenuates breast cancer & metastasis

Abstract 2468: The role of autophagy in lymphangiosarcoma development

FIP200 Suppresses Immune Checkpoint Therapy Responses in Breast Cancers by Limiting AZI2/TBK1/IRF Signaling Independent of Its Canonical Autophagy Function

Abstract 4267: mTORC1-dependent tumors have innate vulnerability to autophagic cell death by HDAC inhibitors

Abstract 1831: Role of autophagy in lymphangiosarcoma initiation and progression

Abstract 4386: Regulation of FIP200 by Her2 and its role in Her2-driven mammary tumors

Abstract 1327: Autophagy facilitates tumor promotion in PyMT tumors through up-regulation of Pparg

Abstract 5882: FAK is required for the survival of tumor cells in MMTV-Wnt1 driven basal-like mammary tumors

Abstract 1627: Kinase-independent function of focal adhesion kinase in lung metastasis of breast cancer

Abstract LB-038: Constitutive activation of mTORC1 in endothelial cells leads to the development and progression of lymphangiosarcoma through VEGF autocrine signaling

Autophagy Differentially Regulates Distinct Breast Cancer Stem-like Cells in Murine Models via EGFR/Stat3 and Tgfβ/Smad Signaling

Abstract 4228: Identification of distinct mammary cancer stem cells with differential requirements for the autophagy regulator FIP200

Abstract 4188: Conditional epithelial cell-specific knockout of CCN6/Wisp3 disrupts normal development of the virgin murine mammary gland

Distinct FAK Activities Determine Progenitor and Mammary Stem Cell Characteristics

Abstract SY36-04: Analysis of autophagy functions in mouse models of breast cancer

Abstract 389: Mice with kinase-dead FAK mutation in endothelial cells are protected from VEGF-induced permeability and are resistant to tumor cell metastasis

Mammary Epithelial-Specific Ablation of the Focal Adhesion Kinase Suppresses Mammary Tumorigenesis by Affecting Mammary Cancer Stem/Progenitor Cells

Compensatory role for proline-rich tyrosine kinase 2 (Pyk2) during angiogenesis in adult mice lacking endothelial cell focal adhesion kinase (FAK)

Stearate inhibits breast cancer cell spreading, motility, and invasion

Mechanism of Cell Cycle Regulation by FIP200 in Human Breast Cancer Cells

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