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Abstract 2468: The role of autophagy in lymphangiosarcoma development

Fuchun Yang, Michael Haas, Jun-Lin Guan

Cancer Res (2021) 81 (13_Supplement): 2468.

DOI: https://doi.org/10.1158/1538-7445.AM2021-2468

Published: 01 July 2021

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Journal Articles

FIP200 Suppresses Immune Checkpoint Therapy Responses in Breast Cancers by Limiting AZI2/TBK1/IRF Signaling Independent of Its Canonical Autophagy Function

Takako Okamoto, Syn Kok Yeo, Mingang Hao, Mary Rose Copley, Michael A. Haas, Song Chen, Jun-Lin Guan

Cancer Res (2020) 80 (17): 3580–3592.

DOI: https://doi.org/10.1158/0008-5472.CAN-20-0519

Published: 02 September 2020

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Includes: Supplementary data

Journal Articles

Abstract 1831: Role of autophagy in lymphangiosarcoma initiation and progression

Fuchun Yang, Shaogang Sun, Jun-Lin Guan

Cancer Res (2019) 79 (13_Supplement): 1831.

DOI: https://doi.org/10.1158/1538-7445.AM2019-1831

Published: 01 July 2019

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Journal Articles

Abstract 4267: mTORC1-dependent tumors have innate vulnerability to autophagic cell death by HDAC inhibitors

Fuchun Yang, Chenran Wang, Shaogang Sun, Michael Haas, Syn Yeo, Jun-Lin Guan

Cancer Res (2019) 79 (13_Supplement): 4267.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4267

Published: 01 July 2019

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Journal Articles

Abstract 4386: Regulation of FIP200 by Her2 and its role in Her2-driven mammary tumors

Mingang Hao, Jun-Lin Guan

Cancer Res (2018) 78 (13_Supplement): 4386.

DOI: https://doi.org/10.1158/1538-7445.AM2018-4386

Published: 01 July 2018

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Journal Articles

Abstract 1327: Autophagy facilitates tumor promotion in PyMT tumors through up-regulation of Pparg

Takako Okamoto, Song Chen, Syn Yeo, Jun-Lin Guan

Cancer Res (2018) 78 (13_Supplement): 1327.

DOI: https://doi.org/10.1158/1538-7445.AM2018-1327

Published: 01 July 2018

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Journal Articles

Abstract 5882: FAK is required for the survival of tumor cells in MMTV-Wnt1 driven basal-like mammary tumors

Ritama Paul, Syn K. Yeo, Ming Luo, Susan Waltz, Jun-Lin Guan

Cancer Res (2017) 77 (13_Supplement): 5882.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5882

Published: 01 July 2017

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Journal Articles

Abstract LB-038: Constitutive activation of mTORC1 in endothelial cells leads to the development and progression of lymphangiosarcoma through VEGF autocrine signaling

Shaogang Sun, Song Chen, Fei Liu, Haige Wu, Jonathan McHugh, Ingrid Bergin, Anita Gupta, Denise Adams, Jun-Lin Guan

Cancer Res (2016) 76 (14_Supplement): LB-038.

DOI: https://doi.org/10.1158/1538-7445.AM2016-LB-038

Published: 15 July 2016

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Journal Articles

Abstract 1627: Kinase-independent function of focal adhesion kinase in lung metastasis of breast cancer

Ming Luo, Max S. Wicha, Jun-Lin Guan

Cancer Res (2016) 76 (14_Supplement): 1627.

DOI: https://doi.org/10.1158/1538-7445.AM2016-1627

Published: 15 July 2016

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Journal Articles

Autophagy Differentially Regulates Distinct Breast Cancer Stem-like Cells in Murine Models via EGFR/Stat3 and Tgfβ/Smad Signaling

Syn Kok Yeo, Jian Wen, Song Chen, Jun-Lin Guan

Cancer Res (2016) 76 (11): 3397–3410.

DOI: https://doi.org/10.1158/0008-5472.CAN-15-2946

Published: 31 May 2016

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Includes: Supplementary data

Journal Articles

Abstract 4228: Identification of distinct mammary cancer stem cells with differential requirements for the autophagy regulator FIP200

Syn K. Yeo, Jian Wen, Song Chen, Jun-Lin Guan

Cancer Res (2015) 75 (15_Supplement): 4228.

DOI: https://doi.org/10.1158/1538-7445.AM2015-4228

Published: 01 August 2015

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Journal Articles

Abstract 4188: Conditional epithelial cell-specific knockout of CCN6/Wisp3 disrupts normal development of the virgin murine mammary gland

Emily E. Martin, Wei Huang, Jun-Lin Guan, Celina G. Kleer

Cancer Res (2015) 75 (15_Supplement): 4188.

DOI: https://doi.org/10.1158/1538-7445.AM2015-4188

Published: 01 August 2015

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Journal Articles

Distinct FAK Activities Determine Progenitor and Mammary Stem Cell Characteristics

Ming Luo, Xiaofeng Zhao, Song Chen, Suling Liu, Max S. Wicha, Jun-Lin Guan

Cancer Res (2013) 73 (17): 5591–5602.

DOI: https://doi.org/10.1158/0008-5472.CAN-13-1351

Published: 02 September 2013

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Includes: Supplementary data

Journal Articles

Abstract SY36-04: Analysis of autophagy functions in mouse models of breast cancer

Jun-Lin Guan

Cancer Res (2012) 72 (8_Supplement): SY36-04.

DOI: https://doi.org/10.1158/1538-7445.AM2012-SY36-04

Published: 15 April 2012

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Journal Articles

Abstract 389: Mice with kinase-dead FAK mutation in endothelial cells are protected from VEGF-induced permeability and are resistant to tumor cell metastasis

Ju-Ock Nam, Lisette M. Acevedo, Erik Goka, Xiao Lei Chen, Colin Walsh, Isabelle Tanjoni, Jun-Lin Guan, Sara M. Weis, David A. Cheresh, David D. Schlaepfer

Cancer Res (2010) 70 (8_Supplement): 389.

DOI: https://doi.org/10.1158/1538-7445.AM10-389

Published: 15 April 2010

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Journal Articles

Mammary Epithelial-Specific Ablation of the Focal Adhesion Kinase Suppresses Mammary Tumorigenesis by Affecting Mammary Cancer Stem/Progenitor Cells

Ming Luo, Huaping Fan, Tamas Nagy, Huijun Wei, Chenran Wang, Suling Liu, Max S. Wicha, Jun-Lin Guan

Cancer Res (2009) 69 (2): 466–474.

DOI: https://doi.org/10.1158/0008-5472.CAN-08-3078

Published: 15 January 2009

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Includes: Supplementary data

Journal Articles

Compensatory role for proline-rich tyrosine kinase 2 (Pyk2) during angiogenesis in adult mice lacking endothelial cell focal adhesion kinase (FAK)

Sara Weis, Ssang-Taek Lim, Kimberly Lutu-Fuga, Leo Barnes, Xiao Lei Chen, Joachim Goethert, Tang-Long Shen, Jun-Lin Guan, David Schlaepfer, David Cheresh

Cancer Res (2008) 68 (9_Supplement): 5846.

Published: 01 May 2008

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Journal Articles

Stearate inhibits breast cancer cell spreading, motility, and invasion

Arig Ibrahim Hashim, Stephanie Cowey, Manuel Pallero, Joanne Murphy-Ullrich, Chuanyu Li, Jun-Lin Guan, Gene P. Siegal, Robert W. Hardy

Cancer Res (2006) 66 (8_Supplement): 427.

Published: 15 April 2006

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Journal Articles

Mechanism of Cell Cycle Regulation by FIP200 in Human Breast Cancer Cells

Zara K. Melkoumian, Xu Peng, Boyi Gan, Xiaoyang Wu, Jun-Lin Guan

Cancer Res (2005) 65 (15): 6676–6684.

DOI: https://doi.org/10.1158/0008-5472.CAN-04-4142

Published: 01 August 2005

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Journal Articles

Inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase.

Hui Miao, Klaus Strebhardt, Elena B. Pasquale, Tang-Long Shen, Jun-Lin Guan, Bing-Cheng Wang

Cancer Res (2005) 65 (9_Supplement): 53.

Published: 01 May 2005

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NARROW

Abstract 2468: The role of autophagy in lymphangiosarcoma development

FIP200 Suppresses Immune Checkpoint Therapy Responses in Breast Cancers by Limiting AZI2/TBK1/IRF Signaling Independent of Its Canonical Autophagy Function

Abstract 1831: Role of autophagy in lymphangiosarcoma initiation and progression

Abstract 4267: mTORC1-dependent tumors have innate vulnerability to autophagic cell death by HDAC inhibitors

Abstract 4386: Regulation of FIP200 by Her2 and its role in Her2-driven mammary tumors

Abstract 1327: Autophagy facilitates tumor promotion in PyMT tumors through up-regulation of Pparg

Abstract 5882: FAK is required for the survival of tumor cells in MMTV-Wnt1 driven basal-like mammary tumors

Abstract LB-038: Constitutive activation of mTORC1 in endothelial cells leads to the development and progression of lymphangiosarcoma through VEGF autocrine signaling

Abstract 1627: Kinase-independent function of focal adhesion kinase in lung metastasis of breast cancer

Autophagy Differentially Regulates Distinct Breast Cancer Stem-like Cells in Murine Models via EGFR/Stat3 and Tgfβ/Smad Signaling

Abstract 4228: Identification of distinct mammary cancer stem cells with differential requirements for the autophagy regulator FIP200

Abstract 4188: Conditional epithelial cell-specific knockout of CCN6/Wisp3 disrupts normal development of the virgin murine mammary gland

Distinct FAK Activities Determine Progenitor and Mammary Stem Cell Characteristics

Abstract SY36-04: Analysis of autophagy functions in mouse models of breast cancer

Abstract 389: Mice with kinase-dead FAK mutation in endothelial cells are protected from VEGF-induced permeability and are resistant to tumor cell metastasis

Mammary Epithelial-Specific Ablation of the Focal Adhesion Kinase Suppresses Mammary Tumorigenesis by Affecting Mammary Cancer Stem/Progenitor Cells

Compensatory role for proline-rich tyrosine kinase 2 (Pyk2) during angiogenesis in adult mice lacking endothelial cell focal adhesion kinase (FAK)

Stearate inhibits breast cancer cell spreading, motility, and invasion

Mechanism of Cell Cycle Regulation by FIP200 in Human Breast Cancer Cells

Inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase.

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