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Journal Articles

Abstract 7303: A novel anti-PD-L1/VEGF bispecific antibody (HLX37) with immune checkpoint inhibition, anti-angiogenic, and antineoplastic activities

Free
Ge Song, Yu-Syuan Chen, Xiaoling Yuan, Chunlei Ge, Xiansong Xiong, Seng Zhu, Hongqing Wei, Jijun Yuan, Chen Hu, Qingyu Wang, Jun Zhu
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 7303.
https://doi.org/10.1158/1538-7445.AM2025-7303
Published: 21 April 2025
View articletitled, Abstract 7303: A novel anti-PD-L1/VEGF bispecific antibody (HLX37) with immune checkpoint inhibition, anti-angiogenic, and antineoplastic activities
Journal Articles

Abstract 6390: Exploratory biomarker analysis of phase 3 ASTRUM-005 study: Serplulimab versus placebo plus chemotherapy for extensive-stage small cell lung cancer

Free
Ying Cheng, Liang Han, Lin Wu, Jun Chen, Hongmei Sun, Guilan Wen, Yinghua Ji, Anastasia Zimina, Jianhua Shi, Zhijie Pan, Jinsheng Shi, Xicheng Wang, Fang Yang, Xinyi Yang, Mengkai Chen, Shiqi Zhong, Qingyu Wang, Jing Li, Jiancheng Cheng, Chen Ling, Yongqiang Shan, Jun Zhu, The ASTRUM-005 Study Group
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6390.
https://doi.org/10.1158/1538-7445.AM2024-6390
Published: 22 March 2024
View articletitled, Abstract 6390: Exploratory biomarker analysis of phase 3 ASTRUM-005 study: Serplulimab versus placebo plus chemotherapy for extensive-stage small cell lung cancer
Journal Articles

Abstract B066: Genome-wide CRISPR screens identify PTGES3 as a druggable AR modulator

Free
Haolong Li, James E. Melnyk, Becky Xu Hua Fu, Siyu Feng, Martin Sjöström, Raunak Shrestha, Meng Zhang, Lisa N. Chesner, Hyun Jin Shin, Marsha Calvert, Jonathan Chou, Rajdeep Das, Emily A. Egusa, Aidan Winters, Jun Zhu, Ashutosh Maheshwari, Junjie T. Hua, Mohammed Alshalalfa, William S. Chen, Bradley A. Stohr, Javed Siddiqui, Bo Huang, Eric J. Small, David A. Quigley, Kevan M. Shokat, Luke A. Gilbert, Felix Y. Feng
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B066.
https://doi.org/10.1158/1538-7445.PRCA2023-B066
Published: 02 June 2023
View articletitled, Abstract B066: Genome-wide CRISPR screens identify PTGES3 as a druggable AR modulator
Journal Articles

Abstract CT105: Preliminary results from the Phase I part of a first-in-human Phase I/II study of HH2853, an EZH1/2 inhibitor, in patients with relapsed/refractory non-Hodgkin lymphomas or advanced solid tumors

Free
Zhengfu Fan, Jin Wang, Meiyu Fang, Johnston Patrick, Tun Han, David Sommerhalder, Jifang Gong, Jilong Yang, Yun Yang, Javier Munoz, Yuqin Song, Zhiming Li, Xian'an Li, Qiuying Ma, Jinming Han, Lin Shen, Jun Zhu
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT105.
https://doi.org/10.1158/1538-7445.AM2023-CT105
Published: 14 April 2023
View articletitled, Abstract CT105: Preliminary results from the Phase I part of a first-in-human Phase I/II study of HH2853, an EZH1/2 inhibitor, in patients with relapsed/refractory non-Hodgkin lymphomas or advanced solid tumors
Journal Articles

Immunotherapeutic Targeting and PET Imaging of DLL3 in Small-Cell Neuroendocrine Prostate Cancer

Available to Purchase
Jonathan Chou, Emily A. Egusa, Sinan Wang, Michelle L. Badura, Fei Lee, Anil P. Bidkar, Jun Zhu, Tanushree Shenoy, Kai Trepka, Troy M. Robinson, Veronica Steri, Jiaoti Huang, Yuzhuo Wang, Eric J. Small, Emily Chan, Bradley A. Stohr, Alan Ashworth, Brant Delafontaine, Sylvie Rottey, Keegan S. Cooke, Nooshin Hashemi Sadraei, Brian Yu, Mark Salvati, Julie M. Bailis, Felix Y. Feng, Robert R. Flavell, Rahul Aggarwal
Journal: Cancer Research
Cancer Res (2023) 83 (2): 301–315.
https://doi.org/10.1158/0008-5472.CAN-22-1433
Published: 18 January 2023
View articletitled, Immunotherapeutic Targeting and PET Imaging of DLL3 in Small-Cell Neuroendocrine Prostate Cancer
Open the PDF for Immunotherapeutic Targeting and PET Imaging of DLL3 in Small-Cell Neuroendocrine Prostate Cancer in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract 1191: Differences in gene mutation characteristics of gastric, intestinal and colorectal stromal tumors

Free
Qian Wang, Hushan Zhang, Sihui Zhao, Jianxun Wang, Ning Ma, Jun Zhu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1191.
https://doi.org/10.1158/1538-7445.AM2021-1191
Published: 01 July 2021
View articletitled, Abstract 1191: Differences in gene mutation characteristics of gastric, intestinal and colorectal stromal tumors
Journal Articles

Abstract 445: Integrated proteogenomic characterization across seven histological types of pediatric brain tumors

Free
Francesca Petralia, Nicole Tignor, Boris Reva, Pichai Raman, Shrabanti Chowdhury, Dmitry Rykunov, Azra Krek, Weiping Ma, Jiayi Ji, Xiaoyu Song, Yuankun Zhu, Jo Lynne Rokita, Antonio Colaprico, Anna Calinawan, Jeffrey R. Whiteaker, Richard G. Ivey, Zeynep Gumus, Selim Kalayci, Gonzalo L. Garcia, Seungyeul Yoo, Lizabeth Katsnelson, Ying Wang, Jacob J. Kennedy, Uliana J. Voytovich, Lei Zhao, Felipe Leprevost, Hui-Yin Chang, Krutika S. Gaonkar, Elizabeth M. Appert, Ximena Cuellar, Jena Lilly, Jun Zhu, Eric E. Schadt, Medhi Mesri, Emily Boja, Tara Hiltka, Henry Rodriguez, Li Ding, Antonio Iavarone, Maciej Wiznerowicz, Alexey I. Nesvizhskii, David Fenyo, Steven Gygi, Amanda Paulovich, Adam C. Resnick, Phillip B. Storm, Brian Rood, Pei Wang, Children's Brain Tumor Tissue Consortium and Clinical Proteomic Tumor Analysis Consortium
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 445.
https://doi.org/10.1158/1538-7445.AM2020-445
Published: 15 August 2020
View articletitled, Abstract 445: Integrated proteogenomic characterization across seven histological types of pediatric brain tumors
Journal Articles

Abstract 1295: Myc family members differentially regulate lineage plasticity in small cell lung cancer

Free
Ayushi S. Patel, Seungyeul Yoo, Ranran Kong, Takashi Sato, Maya Fridrikh, German Nudelman, Charles A. Powell, Jun Zhu, Hideo Watanabe
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1295.
https://doi.org/10.1158/1538-7445.AM2020-1295
Published: 15 August 2020
View articletitled, Abstract 1295: Myc family members differentially regulate lineage plasticity in small cell lung cancer
Journal Articles

Epigenomic Profiling Discovers Trans-lineage SOX2 Partnerships Driving Tumor Heterogeneity in Lung Squamous Cell Carcinoma

Free
Takashi Sato, Seungyeul Yoo, Ranran Kong, Abhilasha Sinha, Prashanth Chandramani-Shivalingappa, Ayushi Patel, Maya Fridrikh, Osamu Nagano, Takashi Masuko, Mary Beth Beasley, Charles A. Powell, Jun Zhu, Hideo Watanabe
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (24): 6084–6100.
https://doi.org/10.1158/0008-5472.CAN-19-2132
Published: 13 December 2019
View articletitled, Epigenomic Profiling Discovers Trans-lineage SOX2 Partnerships Driving Tumor Heterogeneity in Lung Squamous Cell Carcinoma
Open the PDF for Epigenomic Profiling Discovers Trans-lineage SOX2 Partnerships Driving Tumor Heterogeneity in Lung Squamous Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 814: Aurora kinase: A target modulating invasiveness of lung adenocarcinoma

Free
Abhilasha Sinha, Seungyeul Yoo, Hideo Watanabe, Jun Zhu, Charles A. Powell
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 814.
https://doi.org/10.1158/1538-7445.AM2018-814
Published: 01 July 2018
View articletitled, Abstract 814: Aurora kinase: A target modulating invasiveness of lung adenocarcinoma
Journal Articles

Sensitivity to BUB1B Inhibition Defines an Alternative Classification of Glioblastoma

Free
Eunjee Lee, Margaret Pain, Huaien Wang, Jacob A. Herman, Chad M. Toledo, Jennifer G. DeLuca, Raymund L. Yong, Patrick Paddison, Jun Zhu
Journal: Cancer Research
Cancer Res (2017) 77 (20): 5518–5529.
https://doi.org/10.1158/0008-5472.CAN-17-0736
Published: 15 October 2017
View articletitled, Sensitivity to BUB1B Inhibition Defines an Alternative Classification of Glioblastoma
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Includes: Supplementary data
Journal Articles

Abstract LB-253: Novel prognostic gene profiles in tumors for breast cancer survival

Free
Vasily N. Aushev, Marilie D. Gammon, Humberto Parada, Davide Degli Esposti, Hector Hernandez-Vargas, Zdenko Herceg, Susan Teitelbaum, Jun Zhu, Eunjee Lee, Jia Chen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-253.
https://doi.org/10.1158/1538-7445.AM2017-LB-253
Published: 01 July 2017
View articletitled, Abstract LB-253: Novel prognostic gene profiles in tumors for breast cancer survival
Journal Articles

Abstract 4393: Integrative molecular analysis of gene expression and methylation reveals 116 putative key regulator genes of human hepatocarcinogenesis

Free
Amanda J. Craig, Seungyeul Yoo, Verónica Miguela, Delia D'Avola, Pedro Molina-Sánchez, Josep Llovet, Amaia Lujambio, Jun Zhu, Augusto Villanueva
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4393.
https://doi.org/10.1158/1538-7445.AM2017-4393
Published: 01 July 2017
View articletitled, Abstract 4393: Integrative molecular analysis of gene expression and methylation reveals 116 putative key regulator genes of human hepatocarcinogenesis
Journal Articles

Abstract 1512: Functional validation of microRNA activity inferred by ActMiR in bladder cancer

Free
Mireia Castillo-Martin, Ana Collazo Lorduy, EunJee Li, Jun Zhu
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1512.
https://doi.org/10.1158/1538-7445.AM2016-1512
Published: 15 July 2016
View articletitled, Abstract 1512: Functional validation of microRNA activity inferred by ActMiR in bladder cancer
Journal Articles

Abstract 1896: miR-500a is involved in breast cancer-related gene expression pathways and associated with patients survival

Free
Vasily N. Aushev, Davide Degli Esposti, Eunjee Lee, Hector Vargas, Zdenko Herceg, Jun Zhu, Jia Chen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1896.
https://doi.org/10.1158/1538-7445.AM2016-1896
Published: 15 July 2016
View articletitled, Abstract 1896: miR-500a is involved in breast cancer-related gene expression pathways and associated with patients survival
Journal Articles

Abstract B22: Integrative analysis of DNA methylation and gene expression data reveals complex regulation of gastric cancer

Free
Seungyeul Yoo, Suet Yi Leung, Jun Zhu
Journal: Cancer Research
Cancer Res (2016) 76 (2_Supplement): B22.
https://doi.org/10.1158/1538-7445.CHROMEPI15-B22
Published: 14 January 2016
View articletitled, Abstract B22: Integrative analysis of DNA methylation and gene expression data reveals complex regulation of gastric cancer
Journal Articles

Abstract A02: Identification of distinct BUB1B-sensitive and -resistant subtypes of glioblastoma with prognostic value

Free
Eunjee Lee, Patrick J. Paddison, Jun Zhu
Journal: Cancer Research
Cancer Res (2015) 75 (23_Supplement): A02.
https://doi.org/10.1158/1538-7445.BRAIN15-A02
Published: 09 December 2015
View articletitled, Abstract A02: Identification of distinct BUB1B-sensitive and -resistant subtypes of glioblastoma with prognostic value
Journal Articles

Abstract B2-03: Inferred miRNA activity identifies miRNA-mediated regulatory networks underlying multiple cancers

Free
Eunjee Lee, Koichi Ito, Eric E. Schadt, Hanna Y. Irie, Jun Zhu
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_2): B2-03.
https://doi.org/10.1158/1538-7445.COMPSYSBIO-B2-03
Published: 15 November 2015
View articletitled, Abstract B2-03: Inferred miRNA activity identifies miRNA-mediated regulatory networks underlying multiple cancers
Journal Articles

Abstract 1106: Genome-wide CRISPR-Cas9 screens reveal candidate therapeutic targets and tumor suppressor genes for human glioma

Free
Yu Ding, Chad Toledo, Pia Hoellerbauer, Ryan Basom, Emily Girad, Eunjee Lee, Philip Corrin, Qi Lin, Xiao-Nan Li, Do-Hyun Nam, Jeongwu Lee, Jun Zhu, Steven Pollard, Jeffery Delrow, Jim Olson, Patrick J. Paddison
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1106.
https://doi.org/10.1158/1538-7445.AM2015-1106
Published: 01 August 2015
View articletitled, Abstract 1106: Genome-wide CRISPR-Cas9 screens reveal candidate therapeutic targets and tumor suppressor genes for human glioma
Journal Articles

Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival

Free
Mark J. Schliekelman, Ayumu Taguchi, Jun Zhu, Xudong Dai, Jaime Rodriguez, Muge Celiktas, Qing Zhang, Alice Chin, Chee-Hong Wong, Hong Wang, Lisa McFerrin, Suhaida A. Selamat, Chenchen Yang, Evan M. Kroh, Kavita S. Garg, Carmen Behrens, Adi F. Gazdar, Ite A. Laird-Offringa, Muneesh Tewari, Ignacio I. Wistuba, Jean P. Thiery, Samir M. Hanash
Journal: Cancer Research
Cancer Res (2015) 75 (9): 1789–1800.
https://doi.org/10.1158/0008-5472.CAN-14-2535
Published: 30 April 2015
View articletitled, Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival
Open the PDF for Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival in another window
Includes: Supplementary data