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Journal Articles

KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Cancer Res (2015) 75 (18): 3936–3945.

https://doi.org/10.1158/0008-5472.CAN-14-3702

Published: 14 September 2015

View article titled, KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Includes: Supplementary data

Journal Articles

Abstract 4669: Druggable oncogene fusions in lung invasive mucinous adenocarcinoma

Takashi Nakaoku, Koji Tsuta, Hitoshi Ichikawa, Kouya Shiraishi, Hiromi Sakamoto, Masato Enari, Koh Furuta, Yoko Shimada, Hideaki Ogiwara, Shun-ichi Watanabe, Hiroshi Nokihara, Kazuki Yasuda, Masaki Hiramoto, Takao Nammo, Young Hak Kim, Michiaki Mishima, Jun Yokota, Teruhiko Yoshida, Takashi Kohno

Cancer Res (2015) 75 (15_Supplement): 4669.

https://doi.org/10.1158/1538-7445.AM2015-4669

Published: 01 August 2015

View article titled, Abstract 4669: Druggable oncogene fusions in lung invasive mucinous adenocarcinoma

Journal Articles

Development of Lung Adenocarcinomas with Exclusive Dependence on Oncogene Fusions

Motonobu Saito, Yoko Shimada, Kouya Shiraishi, Hiromi Sakamoto, Koji Tsuta, Hirohiko Totsuka, Suenori Chiku, Hitoshi Ichikawa, Mamoru Kato, Shun-ichi Watanabe, Teruhiko Yoshida, Jun Yokota, Takashi Kohno

Cancer Res (2015) 75 (11): 2264–2271.

https://doi.org/10.1158/0008-5472.CAN-14-3282

Published: 31 May 2015

View article titled, Development of Lung Adenocarcinomas with Exclusive Dependence on Oncogene Fusions

Includes: Supplementary data

Journal Articles

Identification of a Functional SNP in the 3′UTR of CXCR2 That Is Associated with Reduced Risk of Lung Cancer

Bríd M. Ryan, Ana I. Robles, Andrew C. McClary, Majda Haznadar, Elise D. Bowman, Sharon R. Pine, Derek Brown, Mohammed Khan, Kouya Shiraishi, Takashi Kohno, Hirokazu Okayama, Ramakrishna Modali, Jun Yokota, Curtis C. Harris

Cancer Res (2015) 75 (3): 566–575.

https://doi.org/10.1158/0008-5472.CAN-14-2101

Published: 01 February 2015

View article titled, Identification of a Functional SNP in the 3′UTR of CXCR2 That Is Associated with Reduced Risk of Lung Cancer

Includes: Supplementary data

Journal Articles

Abstract 2477: Max inactivation in small cell lung cancer disrupts the MYC-SWI/SNF programs and is synthetic lethal with BRG1

Octavio A. Romero-Ferraro, Manuel Torres-Diz, Eva Pros, Antonio Gomez Moruno, Sebastian Moran Salama, Suvi Savola, Luis M. Montuenga, Ruben Pio, Jun Yokota, Montse Sanchez-Cespedes

Cancer Res (2014) 74 (19_Supplement): 2477.

https://doi.org/10.1158/1538-7445.AM2014-2477

Published: 01 October 2014

View article titled, Abstract 2477: Max inactivation in small cell lung cancer disrupts the MYC-SWI/SNF programs and is synthetic lethal with BRG1

Journal Articles

Abstract A61: MiR-101 as a molecular switch for sequential activation of p53-dependent G1 and G2 checkpoints in response to ribosomal stress

Naoto Tsuchiya, Yuko Fujiwara, Hitoshi Nakagama, Takashi Kohno, Jun Yokota

Cancer Res (2013) 73 (19_Supplement): A61.

https://doi.org/10.1158/1538-7445.FBCR13-A61

Published: 15 May 2014

View article titled, Abstract A61: MiR-101 as a molecular switch for sequential activation of p53-dependent G1 and G2 checkpoints in response to ribosomal stress

Journal Articles

Abstract A47: Epigenetic regulation of microRNAs in early stage lung adenocarcinoma

Ana I. Robles, Hirokazu Okayama, Saikartik A. Kumar, Zaneta Franklin, Elise D. Bowman, Daniel Edelman, Holly Stevenson, David Petersen, Ewy Mathé, Yae Kanai, Takashi Kohno, Naoto Tsuchiya, Paul Meltzer, Jun Yokota, Curtis C. Harris

Cancer Res (2013) 73 (19_Supplement): A47.

https://doi.org/10.1158/1538-7445.FBCR13-A47

Published: 15 May 2014

View article titled, Abstract A47: Epigenetic regulation of microRNAs in early stage lung adenocarcinoma

Journal Articles

A Synthetic Lethality–Based Strategy to Treat Cancers Harboring a Genetic Deficiency in the Chromatin Remodeling Factor BRG1

Takahiro Oike, Hideaki Ogiwara, Yuichi Tominaga, Kentaro Ito, Osamu Ando, Koji Tsuta, Tatsuji Mizukami, Yoko Shimada, Hisanori Isomura, Mayumi Komachi, Koh Furuta, Shun-Ichi Watanabe, Takashi Nakano, Jun Yokota, Takashi Kohno

Cancer Res (2013) 73 (17): 5508–5518.

https://doi.org/10.1158/0008-5472.CAN-12-4593

Published: 02 September 2013

View article titled, A Synthetic Lethality–Based Strategy to Treat Cancers Harboring a Genetic Deficiency in the Chromatin Remodeling Factor BRG1

Includes: Supplementary data

Journal Articles

Combination of Protein Coding and Noncoding Gene Expression as a Robust Prognostic Classifier in Stage I Lung Adenocarcinoma

Ichiro Akagi, Hirokazu Okayama, Aaron J. Schetter, Ana I. Robles, Takashi Kohno, Elise D. Bowman, Dickran Kazandjian, Judith A. Welsh, Naohide Oue, Motonobu Saito, Masao Miyashita, Eiji Uchida, Toshihiro Takizawa, Seiichi Takenoshita, Vidar Skaug, Steen Mollerup, Aage Haugen, Jun Yokota, Curtis C. Harris

Cancer Res (2013) 73 (13): 3821–3832.

https://doi.org/10.1158/0008-5472.CAN-13-0031

Published: 30 June 2013

View article titled, Combination of Protein Coding and Noncoding Gene Expression as a Robust Prognostic Classifier in Stage I Lung Adenocarcinoma

Includes: Supplementary data

Journal Articles

Abstract 1214: RET fusion gene: translation to the therapy of lung adenocarcinoma.

Takashi Kohno, Hitoshi Ichikawa, Koji Tsuta, Tatsuji Mizukami, Yoko Shimada, Mamoru Kato, Hiromi Sakamoto, Katsuya Tsuchihara, Shun-ichi Watanabe, Hiroshi Nokihara, Koichi Goto, Jun Yokota, Teruhiko Yoshida, Tatsuhiro Shibata

Cancer Res (2013) 73 (8_Supplement): 1214.

https://doi.org/10.1158/1538-7445.AM2013-1214

Published: 15 April 2013

View article titled, Abstract 1214: RET fusion gene: translation to the therapy of lung adenocarcinoma.

Journal Articles

Abstract 1597: C646, a selective small molecule inhibitor of p300, radiosensitizes cancer cells through enhancement of mitotic catastrophe.

Takahiro Oike, Mayumi Komachi, Hideaki Ogiwara, Jun Yokota, Takashi Nakano, Takashi Kohno

Cancer Res (2013) 73 (8_Supplement): 1597.

https://doi.org/10.1158/1538-7445.AM2013-1597

Published: 15 April 2013

View article titled, Abstract 1597: C646, a selective small molecule inhibitor of p300, radiosensitizes cancer cells through enhancement of mitotic catastrophe.

Journal Articles

Abstract LB-99: EGF receptor tyrosine kinase defines critical prognostic genes of stage IA lung adenocarcinoma

Asuka Nakata, Mai Yamauchi, Rui Yamaguchi, Takashi Kohno, Masao Nagasaki, Teppei Shimamura, Seiya Imoto, Ayumu Saito, Kazuko Ueno, Yousuke Hatanaka, Ryo Yoshida, Tomoyuki Higuchi, Masaharu Nomura, David G. Beer, Jun Yokota, Satoru Miyano, Noriko Gotoh

Cancer Res (2012) 72 (8_Supplement): LB-99.

https://doi.org/10.1158/1538-7445.AM2012-LB-99

Published: 15 April 2012

View article titled, Abstract LB-99: EGF receptor tyrosine kinase defines critical prognostic genes of stage IA lung adenocarcinoma

Journal Articles

Abstract 5721: Garcinol, a histone acetyltransferase inhibitor, radiosensitizes cancer cells by inhibiting non-homologous end joining

Takahiro Oike, Hideaki Ogiwara, Takashi Nakano, Jun Yokota, Takashi Kohno

Cancer Res (2012) 72 (8_Supplement): 5721.

https://doi.org/10.1158/1538-7445.AM2012-5721

Published: 15 April 2012

View article titled, Abstract 5721: Garcinol, a histone acetyltransferase inhibitor, radiosensitizes cancer cells by inhibiting non-homologous end joining

Journal Articles

Identification of Genes Upregulated in ALK-Positive and EGFR/KRAS/ALK-Negative Lung Adenocarcinomas

Cancer Res (2012) 72 (1): 100–111.

https://doi.org/10.1158/0008-5472.CAN-11-1403

Published: 02 January 2012

View article titled, Identification of Genes Upregulated in ALK-Positive and EGFR/KRAS/ALK-Negative Lung Adenocarcinomas

Includes: Supplementary data

Journal Articles

Abstract 4890: ING2, a p53- and chromatin-interacting protein, is essential to mammalian spermatogenesis: Implications in male infertility in humans

Motonobu Saito, Kensuke Kumamoto, Izumi Horikawa, Ana I. Robles, Bungo Furusato, Shu Okamura, Akiteru Goto, Taro Yamashita, Makoto Nagashima, Tin-Lap Lee, Vanessa Baxendale, Owen M. Rennert, Seiichi Takenoshita, Jun Yokota, Isabell A. Sesterhenn, Glenwood E. Trivers, Perwez Hussain, Curtis C. Harris

Cancer Res (2010) 70 (8_Supplement): 4890.

https://doi.org/10.1158/1538-7445.AM10-4890

Published: 15 April 2010

View article titled, Abstract 4890: ING2, a p53- and chromatin-interacting protein, is essential to mammalian spermatogenesis: Implications in male infertility in humans

Journal Articles

Abstract LB-132: Critical prognostic genes for stage I lung cancer are identified from normal growth factor-regulated gene network by overcoming cancer heterogeneity

Noriko Gotoh, Mai Yamauchi, Rui Yamauchi, Masao Nagasaki, Teppei Shimamura, Seiya Imoto, Ayumu Saito, Kazuko Ueno, Yousuke Hatanaka, Ryo Yoshida, Tomoyuki Higuchi, Masaharu Nomura, Takashi Kohno, Jun Yokota, David G. Beer, Satoru Miyano

Cancer Res (2010) 70 (8_Supplement): LB-132.

https://doi.org/10.1158/1538-7445.AM10-LB-132

Published: 15 April 2010

View article titled, Abstract LB-132: Critical prognostic genes for stage I lung cancer are identified from normal growth factor-regulated gene network by overcoming cancer heterogeneity

Journal Articles

Abstract #SY04-2: Inflammation and cancer: Microenvironment, cytokines, microRNA, and p53

Curtis Harris, Nozomu Yanaihara, Masahiro Seike, Xin Wang, Jun Yokota, Carlo Croce

Cancer Res (2009) 69 (9_Supplement): SY04-2.

Published: 01 May 2009

View article titled, Abstract #SY04-2: Inflammation and cancer: Microenvironment, cytokines, microRNA, and p53

Journal Articles

Abstract #5396: Identification of new biomarkers and molecular targets of lung cancers by systems biology approach

Mai Yamauchi, Rui Yamaguchi, Masao Nagasaki, Teppei Shimamura, Seiya Imoto, Ayumu Saito, Kazuko Ueno, Yousuke Hatanaka, Ryo Yoshida, Kazuyuki Okeguchi, Takashi Kohno, Jun Yokota, Satoru Miyano, Noriko Gotoh

Cancer Res (2009) 69 (9_Supplement): 5396.

Published: 01 May 2009

View article titled, Abstract #5396: Identification of new biomarkers and molecular targets of lung cancers by systems biology approach

Journal Articles

Whole Genome Comparison of Allelic Imbalance between Noninvasive and Invasive Small-Sized Lung Adenocarcinomas

Hirofumi Nakanishi, Shingo Matsumoto, Reika Iwakawa, Takashi Kohno, Kenji Suzuki, Koji Tsuta, Yoshihiro Matsuno, Masayuki Noguchi, Eiji Shimizu, Jun Yokota

Cancer Res (2009) 69 (4): 1615–1623.

https://doi.org/10.1158/0008-5472.CAN-08-3218

Published: 12 February 2009

View article titled, Whole Genome Comparison of Allelic Imbalance between Noninvasive and Invasive Small-Sized Lung Adenocarcinomas

Includes: Supplementary data

Journal Articles

Nutlin-3a Activates p53 to Both Down-regulate Inhibitor of Growth 2 and Up-regulate mir-34a, mir-34b, and mir-34c Expression, and Induce Senescence

Kensuke Kumamoto, Elisa A. Spillare, Kaori Fujita, Izumi Horikawa, Taro Yamashita, Ettore Appella, Makoto Nagashima, Seiichi Takenoshita, Jun Yokota, Curtis C. Harris

Cancer Res (2008) 68 (9): 3193–3203.

https://doi.org/10.1158/0008-5472.CAN-07-2780

Published: 01 May 2008

View article titled, Nutlin-3a Activates p53 to Both Down-regulate Inhibitor of Growth 2 and Up-regulate mir-34a, mir-34b, and mir-34c Expression, and Induce Senescence

Includes: Supplementary data

NARROW

KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Abstract 4669: Druggable oncogene fusions in lung invasive mucinous adenocarcinoma

Development of Lung Adenocarcinomas with Exclusive Dependence on Oncogene Fusions

Identification of a Functional SNP in the 3′UTR of CXCR2 That Is Associated with Reduced Risk of Lung Cancer

Abstract 2477: Max inactivation in small cell lung cancer disrupts the MYC-SWI/SNF programs and is synthetic lethal with BRG1

Abstract A61: MiR-101 as a molecular switch for sequential activation of p53-dependent G1 and G2 checkpoints in response to ribosomal stress

Abstract A47: Epigenetic regulation of microRNAs in early stage lung adenocarcinoma

A Synthetic Lethality–Based Strategy to Treat Cancers Harboring a Genetic Deficiency in the Chromatin Remodeling Factor BRG1

Combination of Protein Coding and Noncoding Gene Expression as a Robust Prognostic Classifier in Stage I Lung Adenocarcinoma

Abstract 1214: RET fusion gene: translation to the therapy of lung adenocarcinoma.

Abstract 1597: C646, a selective small molecule inhibitor of p300, radiosensitizes cancer cells through enhancement of mitotic catastrophe.

Abstract LB-99: EGF receptor tyrosine kinase defines critical prognostic genes of stage IA lung adenocarcinoma

Abstract 5721: Garcinol, a histone acetyltransferase inhibitor, radiosensitizes cancer cells by inhibiting non-homologous end joining

Identification of Genes Upregulated in ALK-Positive and EGFR/KRAS/ALK-Negative Lung Adenocarcinomas

Abstract 4890: ING2, a p53- and chromatin-interacting protein, is essential to mammalian spermatogenesis: Implications in male infertility in humans

Abstract LB-132: Critical prognostic genes for stage I lung cancer are identified from normal growth factor-regulated gene network by overcoming cancer heterogeneity

Abstract #SY04-2: Inflammation and cancer: Microenvironment, cytokines, microRNA, and p53

Abstract #5396: Identification of new biomarkers and molecular targets of lung cancers by systems biology approach

Whole Genome Comparison of Allelic Imbalance between Noninvasive and Invasive Small-Sized Lung Adenocarcinomas

Nutlin-3a Activates p53 to Both Down-regulate Inhibitor of Growth 2 and Up-regulate mir-34a, mir-34b, and mir-34c Expression, and Induce Senescence

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