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Journal Articles

Abstract 3249: Targeting polyploid giant cancer cells to overcome resistance to PARP inhibitors in ovarian cancer

Xudong Zhang, Jun Yao, Xiaoran Li, Na Niu, Yan Liu, Anil K. Sood, Jinsong Liu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3249.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3249
Published: 15 June 2022
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Abstract 2435: EZH2 engages TGFb signaling to promote breast cancer bone metastasis via Integrin b1-FAK activation

Lin Zhang, Jingkun Qu, Yutao Qi, Yimin Duan, Yu-Wen Huang, Zhifen Zhou, Ping Li, Jun Yao, Beibei Huang, Shuxing Zhang, Dihua Yu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2435.
DOI: https://doi.org/10.1158/1538-7445.AM2022-2435
Published: 15 June 2022
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Abstract P5-07-03: Disease classification modeling of inflammatory breast cancer based on simultaneous profiling of coding and non-coding RNAs in tumor and blood samples by TGIRT-sequencing

Dennis C. Wylie, Xiaoping Wang, Jun Yao, Hengyi Xu, Toshiaki Iwase, Savitri Krishnamurthy, Naoto T. Ueno, Alan M. Lambowitz
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-07-03.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P5-07-03
Published: 15 February 2022
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Journal Articles

Targeting Glucose Metabolism Sensitizes Pancreatic Cancer to MEK Inhibition

Liang Yan, Bo Tu, Jun Yao, Jing Gong, Alessandro Carugo, Christopher A. Bristow, Qiuyun Wang, Cihui Zhu, Bingbing Dai, Ya'an Kang, Leng Han, Ningping Feng, Yanqing Jin, Jason Fleming, Timothy P. Heffernan, Wantong Yao, Haoqiang Ying
Journal: Cancer Research
Cancer Res (2021) 81 (15): 4054–4065.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-3792
Published: 01 August 2021
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Includes: Supplementary data
Journal Articles

Abstract 2794: Blocking histamine receptor H1 on macrophages with anti-allergy drugs restores T-cell anti-tumor immunity

Hongzhong Li, Yi Xiao, Jun Yao, Xiangliang Yuan, Xuedong Yin, Yuan Zhang, Yohei Saito, Hideo Yagita, Don Gibbons, Dihua Yu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2794.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2794
Published: 01 July 2021
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Journal Articles

Therapy-Induced Transdifferentiation Promotes Glioma Growth Independent of EGFR Signaling

Hwanhee Oh, Inah Hwang, Ja-Young Jang, Lingxiang Wu, Dongqing Cao, Jun Yao, Haoqiang Ying, Jian Yi Li, Yu Yao, Baoli Hu, Qianghu Wang, Hongwu Zheng, Jihye Paik
Journal: Cancer Research
Cancer Res (2021) 81 (6): 1528–1539.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-1810
Published: 15 March 2021
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Includes: Supplementary data
Journal Articles

Abstract A17: Polyploid giant cancer cells lead to evolution of drug resistance in high-grade ovarian cancer

Na Niu, Xiaoran Li, Jun Yao, Anil Sood, Jinsong Liu
Journal: Cancer Research
Cancer Res (2020) 80 (11_Supplement): A17.
DOI: https://doi.org/10.1158/1538-7445.CAMODELS2020-A17
Published: 02 June 2020
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Journal Articles

Targeting Glycosylated PD-1 Induces Potent Antitumor Immunity

Linlin Sun, Chia-Wei Li, Ezra M. Chung, Riyao Yang, Yong-Soo Kim, Andrew H. Park, Yun-Ju Lai, Yi Yang, Yu-Han Wang, Jielin Liu, Yufan Qiu, Kay-Hooi Khoo, Jun Yao, Jennifer L. Hsu, Jong-Ho Cha, Li-Chuan Chan, Jung-Mao Hsu, Heng-Huan Lee, Stephen S. Yoo, Mien-Chie Hung
Journal: Cancer Research
Cancer Res (2020) 80 (11): 2298–2310.
DOI: https://doi.org/10.1158/0008-5472.CAN-19-3133
Published: 02 June 2020
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Includes: Supplementary data
Journal Articles

Sphingosine Kinase 1 Signaling Promotes Metastasis of Triple-Negative Breast Cancer

Sunil Acharya, Jun Yao, Ping Li, Chenyu Zhang, Frank J. Lowery, Qingling Zhang, Hua Guo, Jingkun Qu, Fei Yang, Ignacio I. Wistuba, Helen Piwnica-Worms, Aysegul A. Sahin, Dihua Yu
Journal: Cancer Research
Cancer Res (2019) 79 (16): 4211–4226.
DOI: https://doi.org/10.1158/0008-5472.CAN-18-3803
Published: 15 August 2019
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Includes: Supplementary data
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Abstract 1857: Proscillaridin A induces apoptosis and suppresses non-small cell lung cancer tumor growth via calcium-induced DR4 up-regulation

Run-Ze Li, Xing Xing Fan, Xiao- Jun Yao, Elaine L. Leung, Liang Liu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1857.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1857
Published: 01 July 2019
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Journal Articles

Abstract 1674: Novel direct AMPK activator suppresses non-small cell lung cancer through inhibition of lipid metabolism

Xi Chen, Chun Xie, Xing Xing Fan, Ze Bo Jiang, Vincent Wong, Jia Hui Xu, Xiao Jun Yao, Liang Liu, Elaine L. Leung
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1674.
DOI: https://doi.org/10.1158/1538-7445.AM2018-1674
Published: 01 July 2018
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Journal Articles

Abstract 3034: Overcoming gefitinib resistance in non-small-cell lung cancer by inducing epidermal growth factor receptor (EGFR) degradation via methionine 790 oxidation

Elaine Lai-Han Leung, Xing-Xing Fan, Maria Pik Wong, Zhi-Hong Jiang, Zhong-Qiu Liu, Xiao-Jun Yao, Lin-Lin Lu, Yan-Ling Zhou, Li-Fong Yau, Vicky Pui-Chi Tin, Liang Liu
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3034.
DOI: https://doi.org/10.1158/1538-7445.AM2016-3034
Published: 15 July 2016
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Journal Articles

Abstract 907: Brain microenvironment induced PTEN loss by microRNAs promotes brain metastasis

Lin Zhang, Siyaun Zhang, Jun Yao, Frank J. Lowery Lowery, Qingling Zhang, Wen-Chien Huang, Ping Li, Min Li, Xiao Wang, Chenyu Zhang, Hai Wang, Kenneth Ellis, Mujeeburahiman Cheerathodi, Joseph McCarty, Diane Palmieri, Patricia Steeg, Jodi S Saunus, Sunil Lakhani, Suyun Huang, Aysegul Sahin, Kenneth Aldape, Dihua Yu
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 907.
DOI: https://doi.org/10.1158/1538-7445.AM2016-907
Published: 15 July 2016
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Journal Articles

Abstract LB-119: Single-cell live imaging of paclitaxel-resistant cancer cell generation

Na Niu, Jie Zhang, Ning Zhang, Imelda Mercado-Uribe, Fangfang Tao, Zhenbo Han, Sen Pathak, Asha Multani, Jian Kuang, Jun Yao, Robert Bast, Anil Sood, Mien-Chie Hung, Jinsong Liu
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-119.
DOI: https://doi.org/10.1158/1538-7445.AM2016-LB-119
Published: 15 July 2016
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Journal Articles

Abstract 2099: FoxM1 drives a feed-forward STAT3-activation signaling loop to promote the self-renewal and tumorigenicity of glioblastoma stem cells

Sicong Zhang, Ai-hua Gong, Ping Wei, Aidong Zhou, Jun Yao, Ying Yuan, Frederick Lang, Ganesh Rao, Suyun Huang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2099.
DOI: https://doi.org/10.1158/1538-7445.AM2015-2099
Published: 01 August 2015
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Journal Articles

Abstract 2895: Phosphorylation of EZH2 at T416 by CDK2 promotes development of mammary tumors with basal-like phenotype

Lei Nie, Yongkun Wei, Adam LaBaff, Cheng-Chieh Yang, Weiya Xia, Longfei Huo, Dongping Liu, Yi-Hsin Hsu, Gabriel N. Hortobagyi, Jun Yao, Celina G. Kleer, Mien-Chie Hung
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2895.
DOI: https://doi.org/10.1158/1538-7445.AM2015-2895
Published: 01 August 2015
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Journal Articles

FoxM1 Drives a Feed-Forward STAT3-Activation Signaling Loop That Promotes the Self-Renewal and Tumorigenicity of Glioblastoma Stem-like Cells

Ai-hua Gong, Ping Wei, Sicong Zhang, Jun Yao, Ying Yuan, Ai-dong Zhou, Frederick F. Lang, Amy B. Heimberger, Ganesh Rao, Suyun Huang
Journal: Cancer Research
Cancer Res (2015) 75 (11): 2337–2348.
DOI: https://doi.org/10.1158/0008-5472.CAN-14-2800
Published: 31 May 2015
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Includes: Supplementary data
Journal Articles

Development of Resistance to EGFR-Targeted Therapy in Malignant Glioma Can Occur through EGFR-Dependent and -Independent Mechanisms

Stefan Klingler, Baofeng Guo, Jun Yao, Haiyan Yan, Ling Zhang, Angelina V. Vaseva, Sida Chen, Peter Canoll, James W. Horner, Y. Alan Wang, Ji-Hye Paik, Haoqiang Ying, Hongwu Zheng
Journal: Cancer Research
Cancer Res (2015) 75 (10): 2109–2119.
DOI: https://doi.org/10.1158/0008-5472.CAN-14-3122
Published: 13 May 2015
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Includes: Supplementary data
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CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer

Taku Yoshida, Jee Hyun Kim, Kristopher Carver, Ying Su, Stanislawa Weremowicz, Laura Mulvey, Shoji Yamamoto, Cameron Brennan, Shenglin Mei, Henry Long, Jun Yao, Kornelia Polyak
Journal: Cancer Research
Cancer Res (2015) 75 (7): 1516–1526.
DOI: https://doi.org/10.1158/0008-5472.CAN-14-2443
Published: 31 March 2015
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Includes: Supplementary data
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Abstract 312: Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis

Xian-De Liu, Jun Yao, Durga N. Tripathi, Zhiyong Ding, Yi Xu, Mianen Sun, Jiangwei Zhang, Shanshan Bai, Peter German, Anh Hoang, Lijun Zhou, Xuesong Zhang, Claudio J. Conti, Eleni Efstathiou, Tony N. Eissa, Gordon B. Mills, Cheryl L. Walker, Eric Jonasch
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 312.
DOI: https://doi.org/10.1158/1538-7445.AM2014-312
Published: 01 October 2014
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