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Jun Shen
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Journal Articles

Abstract PO1-28-04: PILHLE-001: neoadjuvant pyrotinib combined with chemotherapy in HR-positive, HER2-low (IHC 2+/FISH-negative) early breast cancer

Chang Gong, Yuan Xia, Yingying Zhu, Yaping Yang, Wenqian Yang, Louis W.C. Chow, Li Ling, Yunjie Zeng, Jiajie Zhong, Ziliang Cheng, Jun Shen, Qun Lin, Yinduo Zeng, Qiang Liu, Erwei Song
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-28-04.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-28-04
Published: 02 May 2024
View article titled, Abstract PO1-28-04: PILHLE-001: neoadjuvant pyrotinib combined with chemotherapy in HR-positive, HER2-low (IHC 2+/FISH-negative) early breast cancer
Journal Articles

Inactivation of the AMPK–GATA3–ECHS1 Pathway Induces Fatty Acid Synthesis That Promotes Clear Cell Renal Cell Carcinoma Growth

Yuan-Yuan Qu, Rui Zhao, Hai-Liang Zhang, Qian Zhou, Fu-Jiang Xu, Xuan Zhang, Wen-Hao Xu, Ning Shao, Shu-Xian Zhou, Bo Dai, Yao Zhu, Guo-Hai Shi, Yi-Jun Shen, Yi-Ping Zhu, Cheng-Tao Han, Kun Chang, Yan Lin, Wei-Dong Zang, Wei Xu, Ding-Wei Ye, Shi-Min Zhao, Jian-Yuan Zhao
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (2): 319–333.
https://doi.org/10.1158/0008-5472.CAN-19-1023
Published: 15 January 2020
View article titled, Inactivation of the AMPK–GATA3–ECHS1 Pathway Induces Fatty Acid Synthesis That Promotes Clear Cell Renal Cell Carcinoma Growth
Open the PDF for Inactivation of the AMPK–GATA3–ECHS1 Pathway Induces Fatty Acid Synthesis That Promotes Clear Cell Renal Cell Carcinoma Growth in another window
Includes: Supplementary data
Journal Articles

Retraction: Inactivation of the Quinone Oxidoreductases NQO1 and NQO2 Strongly Elevates the Incidence and Multiplicity of Chemically Induced Skin Tumors

Jun Shen, Roberto J. Barrios, Anil K. Jaiswal
Journal: Cancer Research
Cancer Res (2018) 78 (21): 6345.
https://doi.org/10.1158/0008-5472.CAN-18-2453
Published: 01 November 2018
View article titled, Retraction: Inactivation of the Quinone Oxidoreductases NQO1 and NQO2 Strongly Elevates the Incidence and Multiplicity of Chemically Induced Skin Tumors
Open the PDF for Retraction: Inactivation of the Quinone Oxidoreductases NQO1 and NQO2 Strongly Elevates the Incidence and Multiplicity of Chemically Induced Skin Tumors in another window
Journal Articles

A Large-Scale, Exome-Wide Association Study of Han Chinese Women Identifies Three Novel Loci Predisposing to Breast Cancer

Bo Zhang, Men-Yun Chen, Yu-Jun Shen, Xian-Bo Zhuo, Ping Gao, Fu-Sheng Zhou, Bo Liang, Jun Zu, Qin Zhang, Sufyan Suleman, Yi-Hui Xu, Min-Gui Xu, Jin-Kai Xu, Chen-Cheng Liu, Nikolaos Giannareas, Ji-Han Xia, Yuan Zhao, Zhong-Lian Huang, Zhen Yang, Huai-Dong Cheng, Na Li, Yan-Yan Hong, Wei Li, Min-Jun Zhang, Ke-Da Yu, Guoliang Li, Meng-Hong Sun, Zhen-Dong Chen, Gong-Hong Wei, Zhi-Min Shao
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (11): 3087–3097.
https://doi.org/10.1158/0008-5472.CAN-17-1721
Published: 31 May 2018
View article titled, A Large-Scale, Exome-Wide Association Study of Han Chinese Women Identifies Three Novel Loci Predisposing to Breast Cancer
Open the PDF for A Large-Scale, Exome-Wide Association Study of Han Chinese Women Identifies Three Novel Loci Predisposing to Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract CT101: A model-based exposure-response (E-R) assessment of a nivolumab (NIVO) 4-weekly (Q4W) dosing schedule across multiple tumor types

Xiaochen Zhao, Vijay Ivaturi, Mathangi Gopalakrishnan, Jun Shen, Yan Feng, Paul Statkevich, Eric Richards, Michelle Rashford, Vicki Goodman, Joga Gobburu, Akintunde Bello, Amit Roy, Shruti Agrawal
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): CT101.
https://doi.org/10.1158/1538-7445.AM2017-CT101
Published: 01 July 2017
View article titled, Abstract CT101: A model-based exposure-response (E-R) assessment of a nivolumab (NIVO) 4-weekly (Q4W) dosing schedule across multiple tumor types
Journal Articles

Tyrosine Kinase Inhibitor Gefitinib Enhances Topotecan Penetration of Gliomas

Angel M. Carcaboso, Mohamed A. Elmeliegy, Jun Shen, Stephen J. Juel, Ziwei M. Zhang, Christopher Calabrese, Lorraine Tracey, Christopher M. Waters, Clinton F. Stewart
Journal: Cancer Research
Cancer Res (2010) 70 (11): 4499–4508.
https://doi.org/10.1158/0008-5472.CAN-09-4264
Published: 01 June 2010
View article titled, Tyrosine Kinase Inhibitor Gefitinib Enhances Topotecan Penetration of Gliomas
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Includes: Supplementary data
Journal Articles

Abstract 1663: A tyrosine kinase inhibitor enhances topotecan penetration of orthotopic glioma xenografts

Angel M. Carcaboso, Mohamed A. Elmeliegy, Jun Shen, Stephen J. Juel, Ziwei M. Zhang, Christopher Calabrese, Lorraine Tracey, Christopher M. Waters, Clinton F. Stewart
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1663.
https://doi.org/10.1158/1538-7445.AM10-1663
Published: 15 April 2010
View article titled, Abstract 1663: A tyrosine kinase inhibitor enhances topotecan penetration of orthotopic glioma xenografts
Journal Articles

Inactivation of the Quinone Oxidoreductases NQO1 and NQO2 Strongly Elevates the Incidence and Multiplicity of Chemically Induced Skin Tumors

Jun Shen, Roberto J. Barrios, Anil K. Jaiswal
Journal: Cancer Research
Cancer Res (2010) 70 (3): 1006–1014.
https://doi.org/10.1158/0008-5472.CAN-09-2938
Published: 31 January 2010
View article titled, Inactivation of the Quinone Oxidoreductases NQO1 and NQO2 Strongly Elevates the Incidence and Multiplicity of Chemically Induced Skin Tumors
Open the PDF for Inactivation of the Quinone Oxidoreductases NQO1 and NQO2 Strongly Elevates the Incidence and Multiplicity of Chemically Induced Skin Tumors in another window
Journal Articles

Compartment-Specific Roles of ATP-Binding Cassette Transporters Define Differential Topotecan Distribution in Brain Parenchyma and Cerebrospinal Fluid

Jun Shen, Angel M. Carcaboso, K. Elaine Hubbard, Michael Tagen, Henry G. Wynn, John C. Panetta, Christopher M. Waters, Mohamed A. Elmeliegy, Clinton F. Stewart
Journal: Cancer Research
Cancer Res (2009) 69 (14): 5885–5892.
https://doi.org/10.1158/0008-5472.CAN-09-0700
Published: 15 July 2009
View article titled, Compartment-Specific Roles of ATP-Binding Cassette Transporters Define Differential Topotecan Distribution in Brain Parenchyma and Cerebrospinal Fluid
Open the PDF for Compartment-Specific Roles of ATP-Binding Cassette Transporters Define Differential Topotecan Distribution in Brain Parenchyma and Cerebrospinal Fluid in another window
Includes: Supplementary data
Journal Articles

Abstract #2915: Assessment of topotecan penetration in orthotopic glioma xenografts using intracerebral microdialysis

Angel Carcaboso, Jun Shen, Mohamed Elmeliegy, Stephen Juel, Clinton Stewart
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2915.
Published: 01 May 2009
View article titled, Abstract #2915: Assessment of topotecan penetration in orthotopic glioma xenografts using intracerebral microdialysis
Journal Articles

Abstract #4719: Nrf2 and drug resistance in breast cancer cells

Jun Shen, Emmanual Unni, Angela Brodie, Anil Jaiswal
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4719.
Published: 01 May 2009
View article titled, Abstract #4719: Nrf2 and drug resistance in breast cancer cells
Journal Articles

Abstract #1342: Loss of FHIT expression due to epigenetic silencing is a frequent event in African American (AA) patients with colorectal cancer (CRC)

Ajay Goel, Thuy-Phuong Nguyen, Alexander Link, Takeshi Nagasaka, Minoru Koi, Wen Sui, Xiang Jun Shen, Norman Sharpless, Cheng Fan, Joseph Galanko, Robert Sandler, Temitope Keku, C. Richard Boland
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1342.
Published: 01 May 2009
View article titled, Abstract #1342: Loss of FHIT expression due to epigenetic silencing is a frequent event in African American (AA) patients with colorectal cancer (CRC)
Journal Articles

Characterization of K-ras mutations and MSI status of sporadic colon cancer in African Americans and Whites

Jenny Besse, Rachel Houlston, Xiang Jun Shen, Janie Peacock, Joseph Galanko, John Carethers, Robert Sandler, Temitope Keku
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1941.
Published: 01 May 2007
View article titled, Characterization of K-ras mutations and MSI status of sporadic colon cancer in African Americans and Whites
Journal Articles

Dexamethasone increases expression and activity of multi-drug resistance transporters at the rat blood-brain barrier

Vishal Narang, Charles Fraga, Narendra Kumar, Jun Shen, Clinton Stewart, Christopher Waters
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2295.
Published: 01 May 2007
View article titled, Dexamethasone increases expression and activity of multi-drug resistance transporters at the rat blood-brain barrier
Journal Articles

Chemoprevention of colon cancer in rats by JTE-522, a selective cyclooxygenase-2 inhibitor

Min Wei, Keiichirou Morimura, Hideki Wanibuchi, Jun Shen, Shoji Fukushima
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 583–584.
Published: 01 May 2005
View article titled, Chemoprevention of colon cancer in rats by JTE-522, a selective cyclooxygenase-2 inhibitor