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Journal Articles

PABPC1L Induces IDO1 to Promote Tryptophan Metabolism and Immune Suppression in Renal Cell Carcinoma

Guannan Shu, Minyu Chen, Wuyuan Liao, Liangmin Fu, Mingjie Lin, Chengpeng Gui, Junjie Cen, Jun Lu, Zhenhua Chen, Jinhuan Wei, Wei Chen, Yinghan Wang, Jiangquan Zhu, Tianxin Zhao, Xiaonan Liu, Jiajia Jing, Guo-chang Liu, Yihui Pan, Junhang Luo, Jiaxing Zhang
Journal: Cancer Research
Cancer Res (2024) 84 (10): 1659–1679.
https://doi.org/10.1158/0008-5472.CAN-23-2521
Published: 15 May 2024
View article titled, PABPC1L Induces IDO1 to Promote Tryptophan Metabolism and Immune Suppression in Renal Cell Carcinoma
Open the PDF for PABPC1L Induces IDO1 to Promote Tryptophan Metabolism and Immune Suppression in Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Neurotransmitter Receptor HTR2B Regulates Lipid Metabolism to Inhibit Ferroptosis in Gastric Cancer

Ru-Hong Tu, Sheng-Ze Wu, Ze-Ning Huang, Qing Zhong, Yin-Hua Ye, Chao-Hui Zheng, Jian-Wei Xie, Jia-Bin Wang, Jian-Xian Lin, Qi-Yue Chen, Chang-Ming Huang, Mi Lin, Jun Lu, Long-Long Cao, Ping Li
Journal: Cancer Research
Cancer Res (2023) 83 (23): 3868–3885.
https://doi.org/10.1158/0008-5472.CAN-23-1012
Published: 01 December 2023
View article titled, Neurotransmitter Receptor HTR2B Regulates Lipid Metabolism to Inhibit Ferroptosis in Gastric Cancer
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Includes: Supplementary data
Journal Articles

Abstract 2451: KRAS activation in gastric cancer stem-like cells promotes tumor angiogenesis and metastasis

Changhwan Yoon, Jun Lu, Yukyung Jun, Bang- Jin Kim, Jacob Till, Jong Hyun Kim, Sara Keshavjee, Sandra Ryeom, Sam Yoon
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2451.
https://doi.org/10.1158/1538-7445.AM2023-2451
Published: 04 April 2023
View article titled, Abstract 2451: KRAS activation in gastric cancer stem-like cells promotes tumor angiogenesis and metastasis
Journal Articles

Extracellular Vesicle-Mediated Transfer of LncRNA IGFL2-AS1 Confers Sunitinib Resistance in Renal Cell Carcinoma

Yihui Pan, Xuanxuan Lu, Guannan Shu, Junjie Cen, Jun Lu, Mi Zhou, Kangbo Huang, Jiaqi Dong, Jiaying Li, Haishan Lin, Hongde Song, Quanhui Xu, Hui Han, Zhenhua Chen, Wei Chen, Junhang Luo, Jinhuan Wei, Jiaxing Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (1): 103–116.
https://doi.org/10.1158/0008-5472.CAN-21-3432
Published: 04 January 2023
View article titled, Extracellular Vesicle-Mediated Transfer of LncRNA <em>IGFL2-AS1</em> Confers Sunitinib Resistance in Renal Cell Carcinoma
Open the PDF for Extracellular Vesicle-Mediated Transfer of LncRNA <em>IGFL2-AS1</em> Confers Sunitinib Resistance in Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract P2-13-32: Pyrotinib in combination with letrozole for estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer: A multicenter, single-arm, phase II trial

Quchang Ouyang, Huihua Xiong, Min Yan, Jincai Zhong, Li Ran, Ting Luo, Liping Liu, Jing Li, Xiaohong Yang, Huawu Xiao, Ning Xie, Hui Wu, Jianxiang Gao, Jun Lu, Xuming Hu, Zheyu Hu, Can Tian, Zhengrong Shui, Min Cao
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-13-32.
https://doi.org/10.1158/1538-7445.SABCS21-P2-13-32
Published: 15 February 2022
View article titled, Abstract P2-13-32: Pyrotinib in combination with letrozole for estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer: A multicenter, single-arm, phase II trial
Journal Articles

Abstract PS13-17: Capecitabine maintaining treatment improves progression-free survival in metastatic breast cancer: A prospective observational study of 669 cases

Quchang Ouyang, Zhe-Yu Hu, Xiaohong Yang, Liping Liu, Jing Li, Huawu Xiao, Jianxiang Gao, Jun Lu, Hui Wu, Ning Xie, Xuming Hu, Can Tian, Zhengrong Shui, Min Cao
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS13-17.
https://doi.org/10.1158/1538-7445.SABCS20-PS13-17
Published: 15 February 2021
View article titled, Abstract PS13-17: Capecitabine maintaining treatment improves progression-free survival in metastatic breast cancer: A prospective observational study of 669 cases
Journal Articles

CSTF2-Induced Shortening of the RAC1 3′UTR Promotes the Pathogenesis of Urothelial Carcinoma of the Bladder

Xin Chen, Jia-Xing Zhang, Jun-Hang Luo, Song Wu, Gang-Jun Yuan, Ning-Fang Ma, Yong Feng, Mu-Yan Cai, Ri-Xin Chen, Jun Lu, Li-Juan Jiang, Jie-Wei Chen, Xiao-Han Jin, Hai-Liang Liu, Wei Chen, Xin-Yuan Guan, Tie-Bang Kang, Fang-Jian Zhou, Dan Xie
Journal: Cancer Research
Cancer Res (2018) 78 (20): 5848–5862.
https://doi.org/10.1158/0008-5472.CAN-18-0822
Published: 15 October 2018
View article titled, CSTF2-Induced Shortening of the <em>RAC1</em> 3′UTR Promotes the Pathogenesis of Urothelial Carcinoma of the Bladder
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Includes: Supplementary data
Journal Articles

Abstract 3005: Whole-genome sequencing identified novel non-coding mutations causal of oncogene activation in T-cell acute lymphoblastic leukemia

Maoxiang Qian, Shaoyan Hu, Hui Zhang, Yu Guo, Jin Yang, Xujie Zhao, Lin Wan, Jun Lu, Jian Pan, Meimei Chang, Shirley K. Kham, Yong Cheng, Chunliang Li, Allen E. Yeoh, Anders Skanderup, Jun J. Yang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3005.
https://doi.org/10.1158/1538-7445.AM2017-3005
Published: 01 July 2017
View article titled, Abstract 3005: Whole-genome sequencing identified novel non-coding mutations causal of oncogene activation in T-cell acute lymphoblastic leukemia
Journal Articles

Abstract 4091: Mesenchymal stem cells drive paclitaxel-resistance in erbB2-overexpressing breast cancer cells via paracrine of NRG-1

Ling Zhu, Jin Wang, Weimin Zuo, Rong Lin, Tingting Lin, Yan Lei, Bingshuang Ren, Jun Lu, Huiyue Dong, Lingjing Lin, Lianghu Huang, Qinghua Wang, Yujie Ma, Hui Lyu, Bolin Liu, Jianming Tan, Shuiliang Wang
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4091.
https://doi.org/10.1158/1538-7445.AM2016-4091
Published: 15 July 2016
View article titled, Abstract 4091: Mesenchymal stem cells drive paclitaxel-resistance in erbB2-overexpressing breast cancer cells via paracrine of NRG-1
Journal Articles

Abstract 5382: Epigenetic targeting of survivin enhances paclitaxel-mediated antitumor activity against non-small-cell lung cancer

Shuiliang Wang, Ling Zhu, Zhiyong Zeng, Lianghu Huang, Fengjin Lin, Rong Lin, Jin Wang, Jun Lu, Qinghua Wang, Lingjing Lin, Huiyue Dong, Weizhen Wu, Kai Zheng, Jinquan Cai, Shunliang Yang, Yujie Ma, Shixin Ye, Wei Liu, Yinghao Yu, Bolin Liu, Jianming Tan
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5382.
https://doi.org/10.1158/1538-7445.AM2015-5382
Published: 01 August 2015
View article titled, Abstract 5382: Epigenetic targeting of survivin enhances paclitaxel-mediated antitumor activity against non-small-cell lung cancer
Journal Articles

The Polyamine Catabolic Enzyme SAT1 Modulates Tumorigenesis and Radiation Response in GBM

Adina Brett-Morris, Bradley M. Wright, Yuji Seo, Vinay Pasupuleti, Junran Zhang, Jun Lu, Raffaella Spina, Eli E. Bar, Maneesh Gujrati, Rebecca Schur, Zheng-Rong Lu, Scott M. Welford
Journal: Cancer Research
Cancer Res (2014) 74 (23): 6925–6934.
https://doi.org/10.1158/0008-5472.CAN-14-1249
Published: 30 November 2014
View article titled, The Polyamine Catabolic Enzyme SAT1 Modulates Tumorigenesis and Radiation Response in GBM
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Includes: Supplementary data
Journal Articles

Abstract 3954: SAT1 (Spermidine/spermine-N1-acetyltrasferase 1) promotes radiation resistance in glioblastoma multiforme

Adina Brett-Morris, Scott M. Welford, Eli Bar, Raffaella Spina, Bradley Wright, Junran Zhang, Jun Lu, Yuji Seo
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3954.
https://doi.org/10.1158/1538-7445.AM2014-3954
Published: 01 October 2014
View article titled, Abstract 3954: SAT1 (Spermidine/spermine-N1-acetyltrasferase 1) promotes radiation resistance in glioblastoma multiforme
Journal Articles

Abstract 4225: Estrogen regulated oncogene SHON mediates the efficacy of anti-estrogen treatment in breast cancer

Bing Xu, Yewon Jung, Jo Perry, Tao Zhu, Peter E. Lobie, Baiqu Huang, Jun Lu, Dong-Xu Liu
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4225.
https://doi.org/10.1158/1538-7445.AM2014-4225
Published: 01 October 2014
View article titled, Abstract 4225: Estrogen regulated oncogene SHON mediates the efficacy of anti-estrogen treatment in breast cancer
Journal Articles

PRMT7 Induces Epithelial-to-Mesenchymal Transition and Promotes Metastasis in Breast Cancer

Ruosi Yao, Hao Jiang, Yuhui Ma, Liping Wang, Lin Wang, Juan Du, Pingfu Hou, Yanyan Gao, Li Zhao, Guannan Wang, Yu Zhang, Dong-Xu Liu, Baiqu Huang, Jun Lu
Journal: Cancer Research
Cancer Res (2014) 74 (19): 5656–5667.
https://doi.org/10.1158/0008-5472.CAN-14-0800
Published: 30 September 2014
View article titled, PRMT7 Induces Epithelial-to-Mesenchymal Transition and Promotes Metastasis in Breast Cancer
Open the PDF for PRMT7 Induces Epithelial-to-Mesenchymal Transition and Promotes Metastasis in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

SHON Is a Novel Estrogen-Regulated Oncogene in Mammary Carcinoma That Predicts Patient Response to Endocrine Therapy

Yewon Jung, Tarek M.A. Abdel-Fatah, Stephen Y.T. Chan, Christopher C. Nolan, Andrew R. Green, Ian O. Ellis, Lili Li, Baiqu Huang, Jun Lu, Bing Xu, Longxin Chen, Runlin Z. Ma, Min Zhang, Jingru Wang, ZhengSheng Wu, Tao Zhu, Jo K. Perry, Peter E. Lobie, Dong-Xu Liu
Journal: Cancer Research
Cancer Res (2013) 73 (23): 6951–6962.
https://doi.org/10.1158/0008-5472.CAN-13-0982
Published: 01 December 2013
View article titled, SHON Is a Novel Estrogen-Regulated Oncogene in Mammary Carcinoma That Predicts Patient Response to Endocrine Therapy
Open the PDF for SHON Is a Novel Estrogen-Regulated Oncogene in Mammary Carcinoma That Predicts Patient Response to Endocrine Therapy in another window
Includes: Supplementary data
Journal Articles

Abstract 832: MicroRNA-30c inhibits human breast tumor chemo-resistance by regulating twinfinlin-1 (TWF1) and IL-11.

Huiping Liu, Jessica Bockhorn, Rachel Dalton, Chika Nwachukwu, Simo Huang, Aleix Prat, Kathy Yee, Ya-Fang Chang, Dezheng Huo, Jun Lu, Eileen Dolan, Charles M. Perou, Olufunmilayo I. Olopade, Michael F. Clarke, Geoffrey Greene
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 832.
https://doi.org/10.1158/1538-7445.AM2013-832
Published: 15 April 2013
View article titled, Abstract 832: MicroRNA-30c inhibits human breast tumor chemo-resistance by regulating twinfinlin-1 (TWF1) and IL-11.
Journal Articles

SOX4 Induces Epithelial–Mesenchymal Transition and Contributes to Breast Cancer Progression

Jianchao Zhang, Qian Liang, Yang Lei, Min Yao, Lili Li, Xiaoge Gao, Jingxin Feng, Yu Zhang, Hongwen Gao, Dong-Xu Liu, Jun Lu, Baiqu Huang
Journal: Cancer Research
Cancer Res (2012) 72 (17): 4597–4608.
https://doi.org/10.1158/0008-5472.CAN-12-1045
Published: 30 August 2012
View article titled, SOX4 Induces Epithelial–Mesenchymal Transition and Contributes to Breast Cancer Progression
Open the PDF for SOX4 Induces Epithelial–Mesenchymal Transition and Contributes to Breast Cancer Progression in another window
Includes: Supplementary data
Journal Articles

Abstract 2532: Triethylenetetramine metabolism and its implication in cancer chemotherapy

Jun Lu, Mingming Li, Malcolm Tingle, Hong Xu, Garth J.S. Cooper
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2532.
https://doi.org/10.1158/1538-7445.AM2011-2532
Published: 15 April 2011
View article titled, Abstract 2532: Triethylenetetramine metabolism and its implication in cancer chemotherapy
Journal Articles

Abstract LB-287: Spermidine/spermine actyltransferase is responsible for the metabolism of triethylenetetramine and other polyamine analogs in humans

Jun Lu, Mingming Li, Hong Xu, Malcolm Tingle, Garth J.S. Cooper
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-287.
https://doi.org/10.1158/1538-7445.AM10-LB-287
Published: 15 April 2010
View article titled, Abstract LB-287: Spermidine/spermine actyltransferase is responsible for the metabolism of triethylenetetramine and other polyamine analogs in humans
Journal Articles

Abstract 2996: Overexpression of potential oncogenic microRNAs defines a new molecular subclass of hepatocellular carcinoma

Sara Toffanin, Yujin Hoshida, Anja Lachenmayer, Laia Cabellos, Jun Lu, Augusto Villanueva, Beatriz Minguez, Radoslav Savic, Derek Y. Chiang, Sasan Roayaie, Jordi Bruix, Myron E. Schwartz, Vincenzo Mazzaferro, Samuel Waxman, Scott L. Friedman, Todd R. Golub, Josep M. Llovet
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2996.
https://doi.org/10.1158/1538-7445.AM10-2996
Published: 15 April 2010
View article titled, Abstract 2996: Overexpression of potential oncogenic microRNAs defines a new molecular subclass of hepatocellular carcinoma