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Journal Articles

Abstract 3659: Early in vivo detection of radiation-induced cardiotoxicity

Jayesh Sharma, Elizabeth Zhang, Xuliang Wang, Junjie Ma, Jun Chen, Gabriele Schiattarella, Joseph Hill, Jaemo Park, Craig Malloy, Vlad Zaha, Prasanna Alluri
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3659.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3659
Published: 15 June 2022
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Abstract CT170: D-0316 in patients with advanced T790M-positive EGFR-mutant non-small cell lung cancer who progressed on prior EGFR-TKI therapy: results from a phase II study (NCT03861156)

Shun Lu, Yiping Zhang, Guojun Zhang, Jianying Zhou, Shundong Cang, Ying Cheng, Gang Wu, Peiguo Cao, Dongqing Lv, Xiangming Jin, Hong Jian, Chengshui Chen, Guanming Jiang, Panwen Tian, Kai Wang, Hui Zhao, Gongyan Chen, Qun Chen, Cuimin Ding, Junquan Yang, Renhua Guo, Guoping Sun, Bin Wang, Liyan Jiang, Wu Zhuang, Zhe Liu, Jian Fang, Yunpeng Liu, Jian Zhang, Jun Chen, Yueyin Pan, Qitao Yu, Min Zhao, Jiuwei Cui, Dianming Li, Tienan Yi, Zhuang Yu, Yan Yang, Yan Zhang, Xiuyi Zhi, Yunchao Huang, Rong Wu, Liangan Chen, Aimin Zang, Lejie Cao, Qingshan Li, Xiaoling Li, Yong Song, Donglin Wang, Shucai Zhang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT170.
DOI: https://doi.org/10.1158/1538-7445.AM2021-CT170
Published: 01 July 2021
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Journal Articles

Abstract LB226: Maternal microbiome protects host against clonal de novo transformation, early onset systemic metastasis, and sudden death

Nagarajan Kannan, Syed Mohammed Musheer Aalam, Xiaojia Tang, Krishna Kalari, Purna Kashyap, Jun Chen, Stephen Johnson, Anguraj Sadanandam, Mark Sherman
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB226.
DOI: https://doi.org/10.1158/1538-7445.AM2021-LB226
Published: 01 July 2021
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Journal Articles

Abstract 2000: Systemic and tumor associated IL-8 correlates with resistance to PD-L1 blockade

Kobe Yuen, Lifen Liu, Congfen Li, Deepali Rishipathak, Patrick Williams, Edward Kadel, Hartmut Koeppen, Shravan Madireddi, Shilpa Keerthivasan, Ying-Jun Chen, Zora Modrusen, Romain Banchereau, Ning Leng, Priti Hegde, Mahrukh Huseni, Sanjeev Mariathasan
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2000.
DOI: https://doi.org/10.1158/1538-7445.AM2020-2000
Published: 15 August 2020
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Abstract PR09: Postmenopause as a key factor in the composition of the Endometrial Cancer Microbiome (ECbiome): Putative role of Porphyromonas somerae in the disease

Marina Walther-Antonio, Dana Walsh, Alexis Hokenstad, Jun Chen, Jayeun Sung, Gregory Jenkins, Nicholas Chia, Heidi Nelson, Andrea Mariani
Journal: Cancer Research
Cancer Res (2020) 80 (8_Supplement): PR09.
DOI: https://doi.org/10.1158/1538-7445.MVC2020-PR09
Published: 15 April 2020
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Journal Articles

Macrophage ABHD5 Suppresses NFκB-Dependent Matrix Metalloproteinase Expression and Cancer Metastasis

Shenglan Shang, Xinran Ji, Lili Zhang, Jun Chen, Chuan Li, Rongchen Shi, Wei Xiang, Xia Kang, Dapeng Zhang, Fan Yang, Rongyang Dai, Peng Chen, Shan Chen, Yongchuan Chen, Yongsheng Li, Hongming Miao
Journal: Cancer Research
Cancer Res (2019) 79 (21): 5513–5526.
DOI: https://doi.org/10.1158/0008-5472.CAN-19-1059
Published: 01 November 2019
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Includes: Supplementary data
Journal Articles

Abstract 4420: MiR-182 suppresses invadopodia formation and metastasis in non-small cell lung cancer by targeting cortactin

Yongwen Li, Hongbing Zhang, Hongyu Liu, Jun Chen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4420.
DOI: https://doi.org/10.1158/1538-7445.AM2018-4420
Published: 01 July 2018
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Journal Articles

Abstract 167: Ibrutinib regulates tumor microenvironment and enhances response to everolimus in renal cell carcinoma mouse models

Jun Chen, Chun-Te Chen, Jing Liu, Jeff Hsu, Taisei Kinoshita, Betty Y. Chang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 167.
DOI: https://doi.org/10.1158/1538-7445.AM2017-167
Published: 01 July 2017
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Journal Articles

MEF2D Transduces Microenvironment Stimuli to ZEB1 to Promote Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer

Li Su, Yongli Luo, Zhi Yang, Jing Yang, Chao Yao, Feifei Cheng, Juanjuan Shan, Jun Chen, Fangfang Li, Limei Liu, Chungang Liu, Yanmin Xu, Lupin Jiang, Deyu Guo, Jesus Prieto, Matías A. Ávila, Junjie Shen, Cheng Qian
Journal: Cancer Research
Cancer Res (2016) 76 (17): 5054–5067.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-0246
Published: 31 August 2016
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Includes: Supplementary data
Journal Articles

Abstract 2321: Ibrutinib enhances antitumor activity in solid tumors when combined with checkpoint inhibitors

Jeff Hsu, Yujun Huang, Chun-Te Chen, Jun Chen, Mint Sirisawad, Betty Y. Chang
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2321.
DOI: https://doi.org/10.1158/1538-7445.AM2016-2321
Published: 15 July 2016
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Journal Articles

Abstract 6: Quantitative assessment of BCL-2:BIM complexes as a pharmacodynamic marker for venetoclax (ABT-199)

Sha Jin, Paul Tapang, Donald J. Osterling, Wenqing Gao, Daniel H. Albert, Andrew J. Souers, Joel D. Leverson, Darren C. Phillips, Jun Chen
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 6.
DOI: https://doi.org/10.1158/1538-7445.AM2015-6
Published: 01 August 2015
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Journal Articles

Abstract 2759: Colorectal cancer cell lines with high BCL-XL and low MCL-1 expression are sensitive to a potent and selective BCL-XL inhibitor

Lloyd T. Lam, Haichao Zhang, John Xue, Paul Hessler, Stephen K. Tahir, Jun Chen, Sha Jin, Andrew J. Souers, Joel D. Leverson
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2759.
DOI: https://doi.org/10.1158/1538-7445.AM2014-2759
Published: 01 October 2014
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Journal Articles

Abstract LB-72: An immunoassay detecting Bcl-2:Bim and Mcl-1:Bim complexes in the phase 1 monotherapy study of the Bcl-2 inhibitor, ABT-199/GDC-0199, in chronic lymphocytic leukemia patients

Jessica Li, Jun Chen, Ward Kadel, Brenda Chyla, evelyn McKeegan, Elizabeth Punnoose, Walter Darbonne
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-72.
DOI: https://doi.org/10.1158/1538-7445.AM2014-LB-72
Published: 01 October 2014
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Journal Articles

Abstract 4966: Establishment and characterization of a paired human non-small cell lung cancer cell lines from primary cancer and metastasis lymph node

Jun Chen, Min Wang, Lingling Zu, Yongwen Li, Weiqiang Wang, Ying Li, Hongyu Liu
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4966.
DOI: https://doi.org/10.1158/1538-7445.AM2014-4966
Published: 01 October 2014
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Journal Articles

Abstract 4564: Inhibitory effects of the BTK inhibitor, ibrutinib, on Her2 amplified breast cancer growth, cell cycle progression and clonogenicity

Jun Chen, Betty Y. Chang, Laurence Elias
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4564.
DOI: https://doi.org/10.1158/1538-7445.AM2014-4564
Published: 01 October 2014
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Journal Articles

Abstract 4607: Expression of Bcl-2 pro-survival family proteins predicts pharmacological responses to ABT-199, a novel and selective Bcl-2 antagonist, in multiple myeloma models.

Deepak Sampath, Elizabeth Punnoose, Erwin Boghaert, Lisa Belmont, Franklin Peale, Nguyen Tan, Jun Chen, Walter Darbonne, Peng Yue, Jason Oeh, Leslie Lee, Wayne J. Fairbrother, Andrew J. Souers, Steven W. Elmore, Joel D. Leverson
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4607.
DOI: https://doi.org/10.1158/1538-7445.AM2013-4607
Published: 15 April 2013
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Journal Articles

Abstract 5591: Clinical significance of EML4-ALK fusion gene and association with EGFR and KRAS gene mutations in 208 Chinese patients with non-small cell lung cancer.

Jun Chen, Hongyu Liu, Ying Li, Yongwen Li, Tong Yang, Sen Wei, Jing Wang, Qinghua Zhou
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5591.
DOI: https://doi.org/10.1158/1538-7445.AM2013-5591
Published: 15 April 2013
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Journal Articles

Abstract 856: Biomarkers of sensitivity and resistance to the BTK inhibitor PCI-32765 in mantle cell lymphoma

Sriram Balasubramanian, Jun Chen, Richard Crowley, Joseph J. Buggy
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 856.
DOI: https://doi.org/10.1158/1538-7445.AM2012-856
Published: 15 April 2012
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Journal Articles

Abstract 4589: Clinical significance of the EML4-ALK fusion gene and association with EGFR and KRAS gene mutation in 208 Chinese patients with non-small cell lung cancer

Jun Chen, Hongyu Liu, tong Yang, Sen Wei, Ying Li, Yuli Wang, Yongwen Li
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4589.
DOI: https://doi.org/10.1158/1538-7445.AM2012-4589
Published: 15 April 2012
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Abstract 4677: Slug is a potential target to restore transforming growth factor-β mediated apoptosis in lung cancer cells

Ajaya Kumar Reka, Moloy Goswami, Himabindu Kurapati, Viritha Kaza, Jun Chen, Venkateshwar G Keshamouni
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4677.
DOI: https://doi.org/10.1158/1538-7445.AM2012-4677
Published: 15 April 2012
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