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Julie Jones
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Journal Articles

Abstract 3717: Defining optimal dose schedules for ATR inhibitors in combination with DNA damaging drugs: Informing clinical studies of VX-970, the first-in-class ATR inhibitor

John Pollard, Phil Reaper, Adele Peek, Stuart Hughes, Scott Gladwell, Julie Jones, Peter Chiu, Mark Wood, Crystal Tolman, Mac Johnson, Peter Littlewood, Marina Penney, Katherine McDermott, Brian Hare, Scott Z. Fields, Mohammed Asmal, Brent O’Carrigan, Timothy A. Yap
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3717.
https://doi.org/10.1158/1538-7445.AM2016-3717
Published: 15 July 2016
View article titled, Abstract 3717: Defining optimal dose schedules for ATR inhibitors in combination with DNA damaging drugs: Informing clinical studies of VX-970, the first-in-class ATR inhibitor
Journal Articles

Abstract 1644: VX-970, the first-in-class inhibitor of the DNA damage repair enzyme ATR

John Pollard, Philip Reaper, Julie Jones, Christopher Barnes, Scott Gladwell, Stuart Hughes, Adele Peak, Hakim Djeha, Amy Hall, David Newsome, Yuxin Wang, Diane Boucher, Brenda Eustace, Yong Gu, Brian Hare, Mac Johnson, Sean Milton, Cheryl Murphy, Darin Takemoto, Crystal Tolman, Mark Wood, Brinley Furey, Marina Penney, Howard Li, Christopher Defranco, Mohammed Asmal, Scott Fields
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1644.
https://doi.org/10.1158/1538-7445.AM2015-1644
Published: 01 August 2015
View article titled, Abstract 1644: VX-970, the first-in-class inhibitor of the DNA damage repair enzyme ATR
Journal Articles

ATR Inhibitors VE-821 and VX-970 Sensitize Cancer Cells to Topoisomerase I Inhibitors by Disabling DNA Replication Initiation and Fork Elongation Responses

Rozenn Jossé, Scott E. Martin, Rajarshi Guha, Pinar Ormanoglu, Thomas D. Pfister, Philip M. Reaper, Christopher S. Barnes, Julie Jones, Peter Charlton, John R. Pollard, Joel Morris, James H. Doroshow, Yves Pommier
Journal: Cancer Research
Cancer Res (2014) 74 (23): 6968–6979.
https://doi.org/10.1158/0008-5472.CAN-13-3369
Published: 30 November 2014
View article titled, ATR Inhibitors VE-821 and VX-970 Sensitize Cancer Cells to Topoisomerase I Inhibitors by Disabling DNA Replication Initiation and Fork Elongation Responses
Open the PDF for ATR Inhibitors VE-821 and VX-970 Sensitize Cancer Cells to Topoisomerase I Inhibitors by Disabling DNA Replication Initiation and Fork Elongation Responses in another window
Includes: Supplementary data