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Journal Articles

Abstract 575: Brain delivery of clinically suitable nanobioconjugates to inhibit glioblastoma growth through extracellular matrix-immune cell crosstalk

Alexander V. Ljubimov, Rameshwar Patil, Hui Ding, Liron Israel, Eggehard Holler, Julia Y. Ljubimova, Tao Sun, Keith L. Black

Cancer Res (2023) 83 (7_Supplement): 575.

https://doi.org/10.1158/1538-7445.AM2023-575

Published: 04 April 2023

View articletitled, Abstract 575: Brain delivery of clinically suitable nanobioconjugates to inhibit glioblastoma growth through extracellular matrix-immune cell crosstalk

Journal Articles

Abstract 2869: Nano-immuno combination therapy to treat brain primary central nervous system lymphoma

Tao Sun, Ekaterina Shatalova, Oliver Braubach, Dmytro Klymyshyn, Eggehard Holler, Jiawei Wang, Lian Li, Jiyuan Yang, Jindrich Kopecek, Julia Y. Ljubimova

Cancer Res (2020) 80 (16_Supplement): 2869.

https://doi.org/10.1158/1538-7445.AM2020-2869

Published: 15 August 2020

View articletitled, Abstract 2869: Nano-immuno combination therapy to treat brain primary central nervous system lymphoma

Journal Articles

Abstract 977: Nano immunotherapeutics crossing blood-brain barrier to activate local brain tumor immune system

Anna Galstyan, Antonella Chiechi, Tao Sun, Ekaterina S. Shatalova, Rameshwar Patil, Keith L. Black, Eggehard Holler, Alexander V. Ljubimov, Hui Ding, Julia Y. Ljubimova

Cancer Res (2019) 79 (13_Supplement): 977.

https://doi.org/10.1158/1538-7445.AM2019-977

Published: 01 July 2019

View articletitled, Abstract 977: Nano immunotherapeutics crossing blood-brain barrier to activate local brain tumor immune system

Journal Articles

Blockade of a Laminin-411–Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk

Cancer Res (2019) 79 (6): 1239–1251.

https://doi.org/10.1158/0008-5472.CAN-18-2725

Published: 15 March 2019

View articletitled, Blockade of a Laminin-411–Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk

Includes: Multimedia, Supplementary data

Journal Articles

Abstract 191: Double blockade of interacting CK2 and EGFR pathways by tumor-targeting nanobioconjugates increases therapeutic efficacy against glioblastoma multiforme

Julia Y. Ljubimova

Cancer Res (2017) 77 (13_Supplement): 191.

https://doi.org/10.1158/1538-7445.AM2017-191

Published: 01 July 2017

View articletitled, Abstract 191: Double blockade of interacting CK2 and EGFR pathways by tumor-targeting nanobioconjugates increases therapeutic efficacy against glioblastoma multiforme

Journal Articles

Abstract 5938: In vivo targeting of laminin-411-β1 integrin-Notch signaling pathway using nanobioconjugate alters glioma microenvironment for effective treatment

Julia Y. Ljubimova

Cancer Res (2017) 77 (13_Supplement): 5938.

https://doi.org/10.1158/1538-7445.AM2017-5938

Published: 01 July 2017

View articletitled, Abstract 5938: In vivo targeting of laminin-411-β1 integrin-Notch signaling pathway using nanobioconjugate alters glioma microenvironment for effective treatment

Journal Articles

Abstract 2692: Nanoconjugates for inhibition of laminin-411-integrin β1-Dll4-Notch1 pathway to treat glioblastoma multiforme

Pallavi R. Gangalum, Alexander V. Ljubimov, Alexandra Chesnokova, Bindu Konda, Hui Ding, Jose Portilla-Arias, Adam Mamelak, Serguei Bannykh, Surasak Phuphanich, Jeremy Rudnick, Jethro Hu, Keith L. Black, Julia Y. Ljubimova

Cancer Res (2014) 74 (19_Supplement): 2692.

https://doi.org/10.1158/1538-7445.AM2014-2692

Published: 01 October 2014

View articletitled, Abstract 2692: Nanoconjugates for inhibition of laminin-411-integrin β1-Dll4-Notch1 pathway to treat glioblastoma multiforme

Journal Articles

Abstract A50: Nanobiocojugates of differential imaging and treatment of brain metastatic tumors

Julia Y. Ljubimova, R. Patil, P. Gangalum, S. Wagner, S. Inoue, H. Ding, J. Portilla, K. Rekechenetskiy, K. Bindu, J. Markman, A. Chesnokova, K. L. Black, E. Holler

Cancer Res (2013) 73 (3_Supplement): A50.

https://doi.org/10.1158/1538-7445.TIM2013-A50

Published: 01 May 2014

View articletitled, Abstract A50: Nanobiocojugates of differential imaging and treatment of brain metastatic tumors

Journal Articles

Abstract 3911: Imaging and treatment of brain metastatic tumors using nanopolymers.

Julia Y. Ljubimova, Rameshwar Patil, Pallavi Gangalum, Shawn Wagner, Satoshi Inoue, Hui Ding, Jose Portilla-Arias, Arthur Rekechenetskiy, Bindu Konda, Janet Markman, Alexandra Chesnokova, Keith L. Black, Eggehard Holler

Cancer Res (2013) 73 (8_Supplement): 3911.

https://doi.org/10.1158/1538-7445.AM2013-3911

Published: 15 April 2013

View articletitled, Abstract 3911: Imaging and treatment of brain metastatic tumors using nanopolymers.

Journal Articles

Abstract 3221: Multifunctional nano-bioconjugate based on poly(β-L-malic acid) for temozolomide delivery for brain tumor treatment

Rameshwar Patil, Satoshi Inoue, José Portilla-Arias, Bindu Konda, Andres Espinoza, Hui Ding, Adam Elramsisy, Keith L. Black, Eggehard Holler, Julia Y. Ljubimova

Cancer Res (2011) 71 (8_Supplement): 3221.

https://doi.org/10.1158/1538-7445.AM2011-3221

Published: 15 April 2011

View articletitled, Abstract 3221: Multifunctional nano-bioconjugate based on poly(β-L-malic acid) for temozolomide delivery for brain tumor treatment

Journal Articles

Abstract 378: Engineering Nanoplatforms based on hydrophobic derivatives of Poly(β, L-malic acid) for tumor drug delivery

Jose Portilla-Arias, Rameshwar Patil, Hui Ding, Sebastian Muñoz-Guerra, Keith L. Black, Julia Y. Ljubimova, Eggehard Holler

Cancer Res (2011) 71 (8_Supplement): 378.

https://doi.org/10.1158/1538-7445.AM2011-378

Published: 15 April 2011

View articletitled, Abstract 378: Engineering Nanoplatforms based on hydrophobic derivatives of Poly(β, L-malic acid) for tumor drug delivery

Journal Articles

Abstract 4428: Inhibition of tumor vascular protein laminin-411 by nanobioconjugate for glioma treatment

Hui Ding, Satoshi Inoue, Alexander V. Ljubimov, Rameshwar Patil, Jose Portilla-Arias, Bindu Konda, Keith L. Black, Eggehard Holler, Julia Y. Ljubimova

Cancer Res (2011) 71 (8_Supplement): 4428.

https://doi.org/10.1158/1538-7445.AM2011-4428

Published: 15 April 2011

View articletitled, Abstract 4428: Inhibition of tumor vascular protein laminin-411 by nanobioconjugate for glioma treatment

Journal Articles

Polymalic Acid–Based Nanobiopolymer Provides Efficient Systemic Breast Cancer Treatment by Inhibiting both HER2/neu Receptor Synthesis and Activity

Satoshi Inoue, Hui Ding, Jose Portilla-Arias, Jinwei Hu, Bindu Konda, Manabu Fujita, Andres Espinoza, Sonal Suhane, Marisa Riley, Marcus Gates, Rameshwar Patil, Manuel L. Penichet, Alexander V. Ljubimov, Keith L. Black, Eggehard Holler, Julia Y. Ljubimova

Cancer Res (2011) 71 (4): 1454–1464.

https://doi.org/10.1158/0008-5472.CAN-10-3093

Published: 14 February 2011

View articletitled, Polymalic Acid–Based Nanobiopolymer Provides Efficient Systemic Breast Cancer Treatment by Inhibiting both HER2/neu Receptor Synthesis and Activity

Journal Articles

Abstract 1447: PDE5 inhibitors increase trastuzumab transport for treatment of HER2-positive metastatic brain tumors

Jinwei Hu, Julia Y. Ljubimova, Satoshi Inoue, Bindu Konda, Rameshwar Patil, Hui Ding, Andres Espinoza, Rong Wang, Chirag Patil, Keith L. Black

Cancer Res (2010) 70 (8_Supplement): 1447.

https://doi.org/10.1158/1538-7445.AM10-1447

Published: 15 April 2010

View articletitled, Abstract 1447: PDE5 inhibitors increase trastuzumab transport for treatment of HER2-positive metastatic brain tumors

Journal Articles

Abstract 3854: Newly designed nanobioconjugate for direct targeting and systemic treatment of HER2-positive breast cancer

Satoshi Inoue, Hui Ding, Bindu Konda, Jose Portilla-Arias, Rameshwar Patil, Andreas Espinoza, Sergiy Rudenkyy, Manuel L. Penichet, Marisa Riley, Marcus Gates, Eggehard Holler, Keith L. Black, Julia Y. Ljubimova

Cancer Res (2010) 70 (8_Supplement): 3854.

https://doi.org/10.1158/1538-7445.AM10-3854

Published: 15 April 2010

View articletitled, Abstract 3854: Newly designed nanobioconjugate for direct targeting and systemic treatment of HER2-positive breast cancer

Journal Articles

Synthesis of polymeric prodrug Polycefin based on biodegradable poly(malic acid) for drug delivery

Bong Seop Lee, Manabu Fujita, Natalya M. Khazenzon, Sebastian Wachsmann-Hogiu, Daniel L. Farkas, Keith L. Black, Julia Y. Ljubimova, Eggehard Holler

Cancer Res (2006) 66 (8_Supplement): 258.

Published: 15 April 2006

View articletitled, Synthesis of polymeric prodrug Polycefin based on biodegradable poly(malic acid) for drug delivery

Journal Articles

A multi-drug delivery system based on poly(malic Acid) for tumor targeting

Manabu Fujita, Natalya M. Khazenzon, Bong-Seop Lee, Eggehard Holler, Keith L. Black, Julia Y. Ljubimova

Cancer Res (2006) 66 (8_Supplement): 720.

Published: 15 April 2006

View articletitled, A multi-drug delivery system based on poly(malic Acid) for tumor targeting

Journal Articles

Development of multifunctional drug delivery system to block human glioma growth and angiogenesis

Manabu Fujita, Natalia M. Khazenzon, Bong-Seop Lee, Eggehard Holler, Keith L. Black, Julia Y. Ljubimova

Cancer Res (2005) 65 (9_Supplement): 330–331.

Published: 01 May 2005

View articletitled, Development of multifunctional drug delivery system to block human glioma growth and angiogenesis

Journal Articles

Delivery of antisense oligonucleotides and transferrin receptor antibody in vitro and in vivo using a new multifunctional drug delivery system based on polymalic acid

Bong-Seop Lee, Manabu Fujita, Julia Y. Ljubimova, Eggehard Holler

Cancer Res (2004) 64 (7_Supplement): 149–150.

Published: 01 April 2004

View articletitled, Delivery of antisense oligonucleotides and transferrin receptor antibody in vitro and in vivo using a new multifunctional drug delivery system based on polymalic acid

Journal Articles

Overexpression of α4 Chain-containing Laminins in Human Glial Tumors Identified by Gene Microarray Analysis

Julia Y. Ljubimova, Alexander J. Lakhter, Anna Loksh, William H. Yong, Mary S. Riedinger, Jeffrey H. Miner, Lydia M. Sorokin, Alexander V. Ljubimov, Keith L. Black

Cancer Res (2001) 61 (14): 5601–5610.

Published: 01 July 2001

View articletitled, Overexpression of α4 Chain-containing Laminins in Human Glial Tumors Identified by Gene Microarray Analysis

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Abstract 575: Brain delivery of clinically suitable nanobioconjugates to inhibit glioblastoma growth through extracellular matrix-immune cell crosstalk

Abstract 2869: Nano-immuno combination therapy to treat brain primary central nervous system lymphoma

Abstract 977: Nano immunotherapeutics crossing blood-brain barrier to activate local brain tumor immune system

Blockade of a Laminin-411–Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk

Abstract 191: Double blockade of interacting CK2 and EGFR pathways by tumor-targeting nanobioconjugates increases therapeutic efficacy against glioblastoma multiforme

Abstract 5938: In vivo targeting of laminin-411-β1 integrin-Notch signaling pathway using nanobioconjugate alters glioma microenvironment for effective treatment

Abstract 2692: Nanoconjugates for inhibition of laminin-411-integrin β1-Dll4-Notch1 pathway to treat glioblastoma multiforme

Abstract A50: Nanobiocojugates of differential imaging and treatment of brain metastatic tumors

Abstract 3911: Imaging and treatment of brain metastatic tumors using nanopolymers.

Abstract 3221: Multifunctional nano-bioconjugate based on poly(β-L-malic acid) for temozolomide delivery for brain tumor treatment

Abstract 378: Engineering Nanoplatforms based on hydrophobic derivatives of Poly(β, L-malic acid) for tumor drug delivery

Abstract 4428: Inhibition of tumor vascular protein laminin-411 by nanobioconjugate for glioma treatment

Polymalic Acid–Based Nanobiopolymer Provides Efficient Systemic Breast Cancer Treatment by Inhibiting both HER2/neu Receptor Synthesis and Activity

Abstract 1447: PDE5 inhibitors increase trastuzumab transport for treatment of HER2-positive metastatic brain tumors

Abstract 3854: Newly designed nanobioconjugate for direct targeting and systemic treatment of HER2-positive breast cancer

Synthesis of polymeric prodrug Polycefin based on biodegradable poly(malic acid) for drug delivery

A multi-drug delivery system based on poly(malic Acid) for tumor targeting

Development of multifunctional drug delivery system to block human glioma growth and angiogenesis

Delivery of antisense oligonucleotides and transferrin receptor antibody in vitro and in vivo using a new multifunctional drug delivery system based on polymalic acid

Overexpression of α4 Chain-containing Laminins in Human Glial Tumors Identified by Gene Microarray Analysis

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