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Abstract 571: The shared mutation and neoantigen landscape of MMR-deficient colorectal cancers suggests immunoediting during tumor evolution

Cancer Res (2019) 79 (13_Supplement): 571.

DOI: https://doi.org/10.1158/1538-7445.AM2019-571

Published: 01 July 2019

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Journal Articles

Abstract 3081: Methylation changes and somatic mutations as early events in Lynch syndrome-associated colorectal cancer

Satu Mäki-Nevala, Satu Valo, Ari Ristimäki, Laura Renkonen-Sinisalo, Anna Lepistö, Jukka-Pekka Mecklin, Päivi Peltomäki

Cancer Res (2018) 78 (13_Supplement): 3081.

DOI: https://doi.org/10.1158/1538-7445.AM2018-3081

Published: 01 July 2018

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Journal Articles

Abstract LB-382: Identification of predisposing genes for small bowel adenocarcinoma by exome sequencing

Ulrika A. Hänninen, Riku Katainen, Tomas Tanskanen, Jiri Hamberg, Ari Ristimäki, Eero Pukkala, Minna Taipale, Jukka-Pekka Mecklin, Mervi Aavikko, Linda M. Forsström, Esa Pitkänen, Netta Mäkinen, Lauri A. Aaltonen

Cancer Res (2018) 78 (13_Supplement): LB-382.

DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-382

Published: 01 July 2018

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Journal Articles

Comprehensive Evaluation of Protein Coding Mononucleotide Microsatellites in Microsatellite-Unstable Colorectal Cancer

Cancer Res (2017) 77 (15): 4078–4088.

DOI: https://doi.org/10.1158/0008-5472.CAN-17-0682

Published: 01 August 2017

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Includes: Supplementary data

Journal Articles

Abstract 4379: Somatic exomic landscape of small intestinal adenocarcinomas

Ulrika A. Hänninen, Riku Katainen, Jiri Hamberg, Jukka-Pekka Mecklin, Linda Forsström, Esa Pitkänen, Netta Mäkinen, Lauri A. Aaltonen

Cancer Res (2017) 77 (13_Supplement): 4379.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4379

Published: 01 July 2017

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Journal Articles

Abstract 171: Comparative genomic analyses of synchronous colorectal cancers by exome sequencing

Ulrika A. Hänninen, Tomas Tanskanen, Riku Katainen, Jan Böhm, Minna Taipale, Jussi Taipale, Jukka-Pekka Mecklin, Netta Mäkinen, Lauri A. Aaltonen

Cancer Res (2016) 76 (14_Supplement): 171.

DOI: https://doi.org/10.1158/1538-7445.AM2016-171

Published: 15 July 2016

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Journal Articles

Abstract 4766: DNA methylation changes in Lynch syndrome associated colorectal adenomas and carcinomas

Satu Valo, Sippy Kaur, Ari Ristimäki, Laura Renkonen-Sinisalo, Heikki Järvinen, Jukka-Pekka Mecklin, Minna Nyström, Päivi Peltomäki

Cancer Res (2015) 75 (15_Supplement): 4766.

DOI: https://doi.org/10.1158/1538-7445.AM2015-4766

Published: 01 August 2015

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Journal Articles

Abstract 2964: Histology-specific patterns of DNA methylation in Lynch-associated and sporadic ovarian cancer

Anni Niskakoski, Sippy Kaur, Synnove Staff, Laura Renkonen-Sinisalo, Heini Lassus, Heikki J. Järvinen, Jukka-Pekka Mecklin, Ralf Bützow, Päivi Peltomäki

Cancer Res (2015) 75 (15_Supplement): 2964.

DOI: https://doi.org/10.1158/1538-7445.AM2015-2964

Published: 01 August 2015

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Journal Articles

Abstract 2744: Familial multiple metastatic small intestine neuroendocrine tumors: searching for genetic susceptibility

Mervi Aavikko, Eevi Kaasinen, Iikki Donner, Kaisa Lehti, Erika Gucciardo, Bideep Shrestha, Jukka-Pekka Mecklin, Järnhult Johannes, Kalle Landerholm, Eero Pukkala, Camilla Schalin-Jäntti, Ari Ristimäki, Pia Vahteristo, Lauri A. Aaltonen

Cancer Res (2015) 75 (15_Supplement): 2744.

DOI: https://doi.org/10.1158/1538-7445.AM2015-2744

Published: 01 August 2015

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Journal Articles

Abstract A57: Nonsense‐mediated decay escaping mutations in microsatellite-unstable colorectal cancer

Alexandra Gylfe, Iina Niittymäki, Leena Ahonen, Heli Lehtonen, Marko Laakso, Johanna Sirkiä, Kari Nousiainen, Jeroen Pouwels, Heikki Järvinen, Kyösti Nuorva, Jukka‐Pekka Mecklin, Ari Ristimäki, Torben Ørntoft, Sampsa Hautaniemi, Auli Karhu, Marko Kallio, Lauri Aaltonen

Cancer Res (2009) 69 (23_Supplement): A57.

DOI: https://doi.org/10.1158/0008-5472.FBCR09-A57

Published: 28 October 2014

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Journal Articles

Abstract 2401: Identification of new target genes in microsatellite unstable colorectal cancer by exome sequencing

Johanna Kondelin, Esa Pitkänen, Alexandra E. Gylfe, Kimmo Palin, Heikki Ristolainen, Riku Katainen, Eevi Kaasinen, Minna Taipale, Jussi Taipale, Laura Renkonen-Sinisalo, Heikki Järvinen, Jan Böhm, Jukka-Pekka Mecklin, Pia Vahteristo, Sari Tuupanen, Lauri A. Aaltonen

Cancer Res (2014) 74 (19_Supplement): 2401.

DOI: https://doi.org/10.1158/1538-7445.AM2014-2401

Published: 01 October 2014

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Journal Articles

Abstract 417: DNA methylation changes in Lynch syndrome and FAP-associated colorectal tumorigenesis

Satu Valo, Sippy Kaur, Ari Ristimäki, Laura Renkonen-Sinisalo, Heikki Järvinen, Jukka-Pekka Mecklin, Minna Nyström, Päivi Peltomäki

Cancer Res (2014) 74 (19_Supplement): 417.

DOI: https://doi.org/10.1158/1538-7445.AM2014-417

Published: 01 October 2014

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Journal Articles

Abstract 5193: Novel candidate oncogenes with mutation hot spots in microsatellite unstable colorectal cancer

Alexandra E. Gylfe, Sari Tuupanen, Ulrika Hänninen, Johanna Kondelin, Heikki Ristolainen, Riku Katainen, Esa Pitkänen, Minna Taipale, Jussi Taipale, Claus Lindbjerg Andersen, Laura Renkonen-Sinisalo, Heikki Järvinen, Jan Böhm, Jukka-Pekka Mecklin, Pia Vahteristo, Lauri A. Aaltonen

Cancer Res (2014) 74 (19_Supplement): 5193.

DOI: https://doi.org/10.1158/1538-7445.AM2014-5193

Published: 01 October 2014

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Journal Articles

Abstract 3156: New candidate oncogenes discovered in microsatellite unstable colorectal cancer.

Cancer Res (2013) 73 (8_Supplement): 3156.

DOI: https://doi.org/10.1158/1538-7445.AM2013-3156

Published: 15 April 2013

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Journal Articles

Abstract 5018: Genetic and epigenetic investigation of breast carcinoma arising in Lynch syndrome families

Johanna E. Lotsari, Annette Gylling, Wael M. Abdel-Rahman, Marjukka Friman, Markku Aarnio, Heikki J. Jarvinen, Jukka-Pekka Mecklin, Teijo Kuopio, Paivi Peltomaki

Cancer Res (2012) 72 (8_Supplement): 5018.

DOI: https://doi.org/10.1158/1538-7445.AM2012-5018

Published: 15 April 2012

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Journal Articles

Abstract 105: Characterizing the exomic profile of MSI colorectal cancer

Johanna K. Kondelin, Alexandra Gylfe, Sari Tuupanen, Heikki Ristolainen, Riku Katainen, Tomas Tanskanen, Heikki Jarvinen, Jukka-Pekka Mecklin, Pia Vahteristo, Lauri A. Aaltonen

Cancer Res (2012) 72 (8_Supplement): 105.

DOI: https://doi.org/10.1158/1538-7445.AM2012-105

Published: 15 April 2012

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Journal Articles

Abstract 3864: Low-penetrance variants underlying familial colorectal cancer

Iina Niittymäki, Eevi Kaasinen, Auli Karhu, Heikki Järvinen, Jukka-Pekka Mecklin, Ian PM Tomlinson, Richard S. Houlston, Lauri A. Aaltonen

Cancer Res (2010) 70 (8_Supplement): 3864.

DOI: https://doi.org/10.1158/1538-7445.AM10-3864

Published: 15 April 2010

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Journal Articles

Mutatome of microsatellite unstable colorectal cancer

Heli Sammalkorpi, Pia Alhopuro, Diego Arango, Mia Bistrom, Sampsa Hautaniemi, Elina Heliovaara, Heikki Jarvinen, Auli Karhu, Jukka-Pekka Mecklin, Iina Niittymaki, Kari Nousiainen, Torben Orntoft, Jani Puhakka, Anniina Raitila, Juha Saharinen, Sari Tuupanen, Lauri Aaltonen

Cancer Res (2008) 68 (9_Supplement): 5783.

Published: 01 May 2008

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Journal Articles

Somatic amplification of the risk allele at colorectal cancer predisposition SNP rs6983267

Sari Tuupanen, Iina Niittymaki, Kari Nousiainen, Sakari Vanharanta, Rainer Lehtonen, Jukka-Pekka Mecklin, Kyosti Nuorva, Heikki Jarvinen, Sampsa Hautaniemi, Auli Karhu, Lauri Aaltonen

Cancer Res (2008) 68 (9_Supplement): 3099.

Published: 01 May 2008

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Journal Articles

Allelic Imbalance at rs6983267 Suggests Selection of the Risk Allele in Somatic Colorectal Tumor Evolution

Sari Tuupanen, Iina Niittymäki, Kari Nousiainen, Sakari Vanharanta, Jukka-Pekka Mecklin, Kyösti Nuorva, Heikki Järvinen, Sampsa Hautaniemi, Auli Karhu, Lauri A. Aaltonen

Cancer Res (2008) 68 (1): 14–17.

DOI: https://doi.org/10.1158/0008-5472.CAN-07-5766

Published: 02 January 2008

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NARROW

Abstract 571: The shared mutation and neoantigen landscape of MMR-deficient colorectal cancers suggests immunoediting during tumor evolution

Abstract 3081: Methylation changes and somatic mutations as early events in Lynch syndrome-associated colorectal cancer

Abstract LB-382: Identification of predisposing genes for small bowel adenocarcinoma by exome sequencing

Comprehensive Evaluation of Protein Coding Mononucleotide Microsatellites in Microsatellite-Unstable Colorectal Cancer

Abstract 4379: Somatic exomic landscape of small intestinal adenocarcinomas

Abstract 171: Comparative genomic analyses of synchronous colorectal cancers by exome sequencing

Abstract 4766: DNA methylation changes in Lynch syndrome associated colorectal adenomas and carcinomas

Abstract 2964: Histology-specific patterns of DNA methylation in Lynch-associated and sporadic ovarian cancer

Abstract 2744: Familial multiple metastatic small intestine neuroendocrine tumors: searching for genetic susceptibility

Abstract A57: Nonsense‐mediated decay escaping mutations in microsatellite-unstable colorectal cancer

Abstract 2401: Identification of new target genes in microsatellite unstable colorectal cancer by exome sequencing

Abstract 417: DNA methylation changes in Lynch syndrome and FAP-associated colorectal tumorigenesis

Abstract 5193: Novel candidate oncogenes with mutation hot spots in microsatellite unstable colorectal cancer

Abstract 3156: New candidate oncogenes discovered in microsatellite unstable colorectal cancer.

Abstract 5018: Genetic and epigenetic investigation of breast carcinoma arising in Lynch syndrome families

Abstract 105: Characterizing the exomic profile of MSI colorectal cancer

Abstract 3864: Low-penetrance variants underlying familial colorectal cancer

Mutatome of microsatellite unstable colorectal cancer

Somatic amplification of the risk allele at colorectal cancer predisposition SNP rs6983267

Allelic Imbalance at rs6983267 Suggests Selection of the Risk Allele in Somatic Colorectal Tumor Evolution

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