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Judith E. Karp
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Journal Articles

CDK2-Mediated Upregulation of TNFα as a Mechanism of Selective Cytotoxicity in Acute Leukemia

Husheng Ding, Nicole D. Vincelette, Cordelia D. McGehee, Mira A. Kohorst, Brian D. Koh, Annapoorna Venkatachalam, X. Wei Meng, Paula A. Schneider, Karen S. Flatten, Kevin L. Peterson, Cristina Correia, Sun-Hee Lee, Mrinal Patnaik, Jonathan A. Webster, Gabriel Ghiaur, B. Douglas Smith, Judith E. Karp, Keith W. Pratz, Hu Li, Larry M. Karnitz, Scott H. Kaufmann
Journal: Cancer Research
Cancer Res (2021) 81 (10): 2666–2678.
https://doi.org/10.1158/0008-5472.CAN-20-1504
Published: 15 May 2021
View article titled, CDK2-Mediated Upregulation of TNFα as a Mechanism of Selective Cytotoxicity in Acute Leukemia
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Includes: Supplementary data
Journal Articles

Abstract 3479: CPX-351 (cytarabine:daunorubicin liposome for injection) anti-leukemia activity is potentiated by Chk1 inhibition

Nicole D. Vincelette, Larry M. Karnitz, Judith E. Karp, Douglas B. Smith, Allan D. Hess, Lawrence D. Mayer, Scott H. Kaufmann
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3479.
https://doi.org/10.1158/1538-7445.AM2015-3479
Published: 01 August 2015
View article titled, Abstract 3479: CPX-351 (cytarabine:daunorubicin liposome for injection) anti-leukemia activity is potentiated by Chk1 inhibition
Journal Articles

Insulin Receptor A and IGF-IR in AML – Response

Andrea E. Wahner Hendrickson, Paul Haluska, Charles Erlichman, Marco Gottardis, Joan E. Carboni, Judith E. Karp, Scott H. Kaufmann
Journal: Cancer Research
Cancer Res (2010) 70 (17): 7010.
https://doi.org/10.1158/0008-5472.CAN-10-1920
Published: 31 August 2010
View article titled, Insulin Receptor A and IGF-IR in AML – Response
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Journal Articles

Abstract 4539: Anti-leukemic activity of mitochondria-targeted asymmetrical 2,2′-binaphthoquinones

Rebecca M. Ricklis, Milena Vuica-Ross, Robert A. Brodsky, Edward Sausville, Chi V. Dang, Judith E. Karp, Ashkan Emadi
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4539.
https://doi.org/10.1158/1538-7445.AM10-4539
Published: 15 April 2010
View article titled, Abstract 4539: Anti-leukemic activity of mitochondria-targeted asymmetrical 2,2′-binaphthoquinones
Journal Articles

Progressive Chromatin Repression and Promoter Methylation of CTNNA1 Associated with Advanced Myeloid Malignancies

Ying Ye, Michael A. McDevitt, Mingzhou Guo, Wei Zhang, Oliver Galm, Steven D. Gore, Judith E. Karp, Jaroslaw P. Maciejewski, Jeanne Kowalski, Hua-Ling Tsai, Lukasz P. Gondek, Hsing-Chen Tsai, Xiaofei Wang, Craig Hooker, B. Douglas Smith, Hetty E. Carraway, James G. Herman
Journal: Cancer Research
Cancer Res (2009) 69 (21): 8482–8490.
https://doi.org/10.1158/0008-5472.CAN-09-1153
Published: 28 October 2009
View article titled, Progressive Chromatin Repression and Promoter Methylation of <em>CTNNA1</em> Associated with Advanced Myeloid Malignancies
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Includes: Supplementary data
Journal Articles

Expression of Insulin Receptor Isoform A and Insulin-like Growth Factor-1 Receptor in Human Acute Myelogenous Leukemia: Effect of the Dual-Receptor Inhibitor BMS-536924 In vitro

Andrea E. Wahner Hendrickson, Paul Haluska, Paula A. Schneider, David A. Loegering, Kevin L. Peterson, Ricardo Attar, B. Douglas Smith, Charles Erlichman, Marco Gottardis, Judith E. Karp, Joan M. Carboni, Scott H. Kaufmann
Journal: Cancer Research
Cancer Res (2009) 69 (19): 7635–7643.
https://doi.org/10.1158/0008-5472.CAN-09-0511
Published: 01 October 2009
View article titled, Expression of Insulin Receptor Isoform A and Insulin-like Growth Factor-1 Receptor in Human Acute Myelogenous Leukemia: Effect of the Dual-Receptor Inhibitor BMS-536924 <em>In vitro</em>
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Includes: Supplementary data
Journal Articles

Combined DNA Methyltransferase and Histone Deacetylase Inhibition in the Treatment of Myeloid Neoplasms

Steven D. Gore, Stephen Baylin, Elizabeth Sugar, Hetty Carraway, Carole B. Miller, Michael Carducci, Michael Grever, Oliver Galm, Tianna Dauses, Judith E. Karp, Michelle A. Rudek, Ming Zhao, B. Douglas Smith, Jasper Manning, Anchalee Jiemjit, George Dover, Abbie Mays, James Zwiebel, Anthony Murgo, Li-Jun Weng, James G. Herman
Journal: Cancer Research
Cancer Res (2006) 66 (12): 6361–6369.
https://doi.org/10.1158/0008-5472.CAN-06-0080
Published: 15 June 2006
View article titled, Combined DNA Methyltransferase and Histone Deacetylase Inhibition in the Treatment of Myeloid Neoplasms
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Journal Articles

Factors affecting the pharmacokinetic profile of MS-275, a histone deacetylase inhibitor, in humans

Milin R. Acharya, Judith E. Karp, Edward A. Sausville, Kyunghwa Hwang, Qin Ryan, Ivana Gojo, Jurgen Venitz, William D. Figg, Alex Sparreboom
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 937.
Published: 01 May 2005
View article titled, Factors affecting the pharmacokinetic profile of MS-275, a histone deacetylase inhibitor, in humans
Journal Articles

Prostate Cancer Prevention: Investigational Approaches and Opportunities

Judith E. Karp, Andrew Chiarodo, Otis Brawley, Gary J. Kelloff
Journal: Cancer Research
Cancer Res (1996) 56 (24): 5547–5556.
Published: 01 December 1996
View article titled, Prostate Cancer Prevention: Investigational Approaches and Opportunities
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Journal Articles

Changes in Topoisomerase I Levels and Localization during Myeloid Maturation in Vitro and in Vivo

Scott H. Kaufmann, Martin Charron, Philip J. Burke, Judith E. Karp
Journal: Cancer Research
Cancer Res (1995) 55 (6): 1255–1260.
Published: 01 March 1995
View article titled, Changes in Topoisomerase I Levels and Localization during Myeloid Maturation <em>in Vitro</em> and <em>in Vivo</em>
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Journal Articles

New Directions in Molecular Medicine

Judith E. Karp, Samuel Broder
Journal: Cancer Research
Cancer Res (1994) 54 (3): 653–665.
Published: 01 February 1994
View article titled, New Directions in Molecular Medicine
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Journal Articles

Acquired Immunodeficiency Syndrome and Non-Hodgkin's Lymphomas

Judith E. Karp, Samuel Broder
Journal: Cancer Research
Cancer Res (1991) 51 (18): 4743–4756.
Published: 01 September 1991
View article titled, Acquired Immunodeficiency Syndrome and Non-Hodgkin's Lymphomas
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Journal Articles

Topoisomerase II Levels during Granulocytic Maturation in Vitro and in Vivo

Scott H. Kaufmann, Sharon J. McLaughlin, Michael B. Kastan, Leroy F. Liu, Judith E. Karp, Philip J. Burke
Journal: Cancer Research
Cancer Res (1991) 51 (13): 3534–3543.
Published: 01 July 1991
View article titled, Topoisomerase II Levels during Granulocytic Maturation <em>in Vitro</em> and <em>in Vivo</em>
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Journal Articles

Phase I and Pharmacodynamic Study of Taxol in Refractory Acute Leukemias

Eric K. Rowinsky, Philip J. Burke, Judith E. Karp, Robert W. Tucker, David S. Ettinger, Ross C. Donehower
Journal: Cancer Research
Cancer Res (1989) 49 (16): 4640–4647.
Published: 01 August 1989
View article titled, Phase I and Pharmacodynamic Study of Taxol in Refractory Acute Leukemias
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Journal Articles

Growth Response of Residual Leukemia after Initial Drug Therapy

Judith E. Karp, Philip J. Burke
Journal: Cancer Research
Cancer Res (1986) 46 (8): 4205–4207.
Published: 01 August 1986
View article titled, Growth Response of Residual Leukemia after Initial Drug Therapy
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Journal Articles

Drug Induced Host Factors Which Stimulate Growth of Residual Leukemia in Lewis × Brown Norway F1 (LEW-BN) Rats

Philip J. Burke, Judith E. Karp, Patricia L. Saylor
Journal: Cancer Research
Cancer Res (1986) 46 (4_Part_1): 1813–1816.
Published: 01 April 1986
View article titled, Drug Induced Host Factors Which Stimulate Growth of Residual Leukemia in Lewis × Brown Norway F<sub>1</sub> (LEW-BN) Rats
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Journal Articles

Direct Relationship of Marrow Cell Growth and 1-β-d-Arabinofuranosylcytosine Metabolism1

Judith E. Karp, Ross C. Donehower, Gregory B. Dole, Philip J. Burke
Journal: Cancer Research
Cancer Res (1984) 44 (11): 5046–5050.
Published: 01 November 1984
View article titled, Direct Relationship of Marrow Cell Growth and 1-β-<sc>d</sc>-Arabinofuranosylcytosine Metabolism<sup>1</sup>
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Journal Articles

Correlation of Proliferative and Clonogenic Tumor Cells in Multiple Myeloma

Judith E. Karp, Philip J. Burke, Patricia L. Saylor, Richard L. Humphrey
Journal: Cancer Research
Cancer Res (1984) 44 (9): 4197–4200.
Published: 01 September 1984
View article titled, Correlation of Proliferative and Clonogenic Tumor Cells in Multiple Myeloma
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Journal Articles

Timed Sequential Therapy of Human Leukemia Based upon the Response of Leukemic Cells to Humoral Growth Factors

Philip J. Burke, Judith E. Karp, Hayden G. Braine, William P. Vaughan
Journal: Cancer Research
Cancer Res (1977) 37 (7_Part_1): 2138–2146.
Published: 01 July 1977
View article titled, Timed Sequential Therapy of Human Leukemia Based upon the Response of Leukemic Cells to Humoral Growth Factors
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Journal Articles

Enhancement of Drug Cytotoxicity by Recruitment of Leukemic Myeloblasts with Humoral Stimulation

Judith E. Karp, Philip J. Burke
Journal: Cancer Research
Cancer Res (1976) 36 (10): 3600–3603.
Published: 01 October 1976
View article titled, Enhancement of Drug Cytotoxicity by Recruitment of Leukemic Myeloblasts with Humoral Stimulation
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