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Juan Miguel Mosquera
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Journal Articles

Abstract 3437: Whole genome and transcriptome sequencing of a pan cancer cohort unearths novel therapeutic avenues

Majd Al Assaad, Hui-Hsuan Kuo, Jones Nauseef, Max F. Levine, Gunes Gundem, Juan S. Medina-Martínez, Jyothi Manohar, Michael Sigouros, Ahmed Elsaeed, David Wilkes, Elli Papaemmanuil, Eloise Chapman, Scott T. Tagawa, Allyson Ocean, Cora N. Sternberg, Eleni Andreopoulou, Manish Shah, Andrea Sboner, Kevin Holcomb, David Nanus, Laura Martin, Olivier Elemento, Juan Miguel Mosquera
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3437.
https://doi.org/10.1158/1538-7445.AM2023-3437
Published: 04 April 2023
View article titled, Abstract 3437: Whole genome and transcriptome sequencing of a pan cancer cohort unearths novel therapeutic avenues
Journal Articles

Abstract 2149: A whole genome sequencing classifier of homologous recombination deficiency

Kevin Hadi, Gunes Gundem, Max F. Levine, Aditya Deshpande, Minal Patel, Stan Skzrypczak, Majd Al Assaad, Juan Miguel Mosquera, Olivier Elemento, Andrew L. Kung, Juan S. Medina-Martínez, Elli Papaemmanuil
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2149.
https://doi.org/10.1158/1538-7445.AM2023-2149
Published: 04 April 2023
View article titled, Abstract 2149: A whole genome sequencing classifier of homologous recombination deficiency
Journal Articles

Abstract 2143: Cancer of unknown Primary (CUP): Beyond the identification of the site of origin by an integrative genomic approach

Majd Al Assaad, Michael Sigouros, Jyothi Manohar, Daniela Guevara, Zoia Antysheva, Daria Kiriy, Alexandra Boyko, Naira Samarina, Nara Shin, Viktor Svekolkin, Svetlana Podsvirova, Noel English, Alaina Villarreal, Brianna McKenna, Cagdas Tazearslan, Diana Shamsutdinova, Vladimir Kushnarev, Troy Kane, David Wilkes, Manish Shah, Barbara Ma, Scott T. Tagawa, David Nanus, Jones Nauseef, Olivier Elemento, Juan Miguel Mosquera, Cora N. Sternberg
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2143.
https://doi.org/10.1158/1538-7445.AM2023-2143
Published: 04 April 2023
View article titled, Abstract 2143: Cancer of unknown Primary (CUP): Beyond the identification of the site of origin by an integrative genomic approach
Journal Articles

Abstract NG10: Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets

Fanying Tang, Duo Xu, Shangqian Wang, Chen Khuan Wong, Alexander Martinez-Fundichely, Cindy J. Lee, Sandra Cohen, Jane Park, Corinne E. Hill, Kenneth Eng, Rohan Bareja, Teng Han, Eric Minwei Liu, Ann Palladino, Wei Di, Dong Gao, Wassim Abida, Shaham Beg, Loredana Puca, Maximiliano Meneses, Elisa de Stanchina, Michael F. Berger, Anuradha Gopalan, Lukas E. Dow, Juan Miguel Mosquera, Himisha Beltran, Cora N. Sternberg, Ping Chi, Howard I. Scher, Andrea Sboner, Yu Chen, Ekta Khurana
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): NG10.
https://doi.org/10.1158/1538-7445.AM2023-NG10
Published: 04 April 2023
View article titled, Abstract NG10: Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets
Journal Articles

Abstract 167: Assessment of homologous recombination deficiency cancer signatures with patient-derived tumor organoid models

Hui-Hsuan Kuo, Madj Al Assaad, John Nguyen, Jenna Moyer, Hamza Gokozan, Sarah Ackermann, Jared Capuano, Jyothi Manohar, Michael Sigouros, Andrea Sboner, Juan Miguel Mosquera, Olivier Elemento, Maria Laura Martin
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 167.
https://doi.org/10.1158/1538-7445.AM2023-167
Published: 04 April 2023
View article titled, Abstract 167: Assessment of homologous recombination deficiency cancer signatures with patient-derived tumor organoid models
Journal Articles

Abstract B026: Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets

Fanying Tang, Duo Xu, Shangqian Wang, Chen Khuan Wong, Alexander Martinez-Fundichely, Cindy Lee, Sandra Cohen, Jane Park, Corinne Hill, Kenneth Eng, Rohan Bareja, Teng Han, Eric Minwei Liu, Ann Palladino, Wei Di, Dong Gao, Wassim Abida, Shaham Beg, Loredana Puca, Maximiliano Meneses, Elisa De Stanchina, Michael Berger, Anuradha Gopalan, Lukas Dow, Juan Miguel Mosquera, Himisha Beltran, Cora Sternberg, Ping Chi, Howard Scher, Andrea Sboner, Yu Chen, Ekta Khurana
Journal: Cancer Research
Cancer Res (2022) 82 (23_Supplement_2): B026.
https://doi.org/10.1158/1538-7445.CancEpi22-B026
Published: 01 December 2022
View article titled, Abstract B026: Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets
Journal Articles

Abstract 5310: Chromatin accessibility landscape and transcriptome of castration resistant prostate cancers reveals novel subtypes and diverse master regulators

Fanying Tang, Chen Khuan Wong, Sandra Cohen, Cindy Lee, Minwei Liu, Rohan Bareja, Kenneth Eng, Shaham Beg, Loredana Puca, Cora Sternberg, Juan Miguel Mosquera, Himisha Beltran, Andrea Sboner, Yu Chen, Ekta Khurana
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5310.
https://doi.org/10.1158/1538-7445.AM2020-5310
Published: 15 August 2020
View article titled, Abstract 5310: Chromatin accessibility landscape and transcriptome of castration resistant prostate cancers reveals novel subtypes and diverse master regulators
Journal Articles

Abstract 909: Single-cell transcriptomic profiling of non-small cell lung cancer uncovers inter- and intracell population structure across TCGA lung adenocarcinoma and lung squamous cancer subtypes

Kofi E. Gyan, Aditya Deshpande, Shaham Beg, Huasong Tian, Joel Rosiene, Marlon Stoeckius, Peter Smibert, Davide Risso, Juan Miguel Mosquera, Marcin Imielinski
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 909.
https://doi.org/10.1158/1538-7445.AM2019-909
Published: 01 July 2019
View article titled, Abstract 909: Single-cell transcriptomic profiling of non-small cell lung cancer uncovers inter- and intracell population structure across TCGA lung adenocarcinoma and lung squamous cancer subtypes
Journal Articles

Abstract A074: Aberrant activation of a gastrointestinal transcriptional circuit in prostate cancer mediates castration resistance

Shipra Shukla, Joanna Cyrta, Devan Murphy, Edward Walczak, Leili Ran, Praveen Agrawal, Yuanyuan Xie, Yuedan Chen, Shangqian Wang, Yu Zhan, Wai Pung E. Wong, Andrea Sboner, Himisha Beltran, Juan-Miguel Mosquera, Jessica Sher, Zhen Cao, John Wongvipat, Richard P. Koche, Anuradha Gopalan, Deyou Zheng, Mark Rubin, Howard I. Scher, Ping Chi, Yu Chen
Journal: Cancer Research
Cancer Res (2018) 78 (16_Supplement): A074.
https://doi.org/10.1158/1538-7445.PRCA2017-A074
Published: 14 August 2018
View article titled, Abstract A074: Aberrant activation of a gastrointestinal transcriptional circuit in prostate cancer mediates castration resistance
Journal Articles

Abstract 1947: Rovalpituzumab tesirine as a therapeutic agent for neuroendocrine prostate cancer

Loredana Puca, Verena Sailor, Katie Gavyert, Etienne Dardenne, Kumiko Isse, Michael Sigouros, David M. Nanus, Scott T. Tagawa, Juan Miguel Mosquera, Laura Saunders, Himisha Beltran
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1947.
https://doi.org/10.1158/1538-7445.AM2018-1947
Published: 01 July 2018
View article titled, Abstract 1947: Rovalpituzumab tesirine as a therapeutic agent for neuroendocrine prostate cancer
Journal Articles

Abstract 992: Patient-derived tumor organoids of neuroendocrine prostate cancer

Loredana Puca, Rohan Bareja, Reid Shaw, Wouter Karthaus, Dong Gao, Chantal Pauli, Juan Miguel Mosquera, Joanna Cyrta, Rachele Rosati, Rema Rao, Andrea Sboner, Carla Grandori, Giorgio Inghirami, Yu Chen, Mark A. Rubin, Himisha Beltran
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 992.
https://doi.org/10.1158/1538-7445.AM2017-992
Published: 01 July 2017
View article titled, Abstract 992: Patient-derived tumor organoids of neuroendocrine prostate cancer
Journal Articles

Abstract NG06: Genomic dissection of the clonal evolution dynamics of chemotherapy-resistant urothelial carcinoma

Bishoy M. Faltas, Davide Prandi, Scott T. Tagawa, Ana M. Molina, David M. Nanus, Cora Sternberg, Jonathan Rosenberg, Juan Miguel Mosquera, Brian Robinson, Olivier Elemento, Andrea Sboner, Himisha Beltran, Francesca Demichelis, Mark A. Rubin
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): NG06.
https://doi.org/10.1158/1538-7445.AM2017-NG06
Published: 01 July 2017
View article titled, Abstract NG06: Genomic dissection of the clonal evolution dynamics of chemotherapy-resistant urothelial carcinoma
Journal Articles

Abstract 3098: Epigenetic therapy to target neuroendocrine prostate cancer using precision medicine models

Loredana Puca, Wouter R. Karthaus, Dong Gao, John Wongvipat, Andrea Sboner, Marcello Gaudiano, Chantal Pauli, Rema A. Rao, Juan Miguel Mosquera, Joanna Cyrta, Theresa Y. MacDonald, Giorgio Ga Inghirami, Yu Chen, Mark A. Rubin, Himisha Beltran
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3098.
https://doi.org/10.1158/1538-7445.AM2016-3098
Published: 15 July 2016
View article titled, Abstract 3098: Epigenetic therapy to target neuroendocrine prostate cancer using precision medicine models
Journal Articles

Abstract 887: N-Myc drives neuroendocrine prostate cancer

Etienne Dardenne, Himisha Beltran, Kaitlyn Gayvert, Matteo Benelli, Adeline Berger, Loredana Puca, Joanna Cyrta, Andrea Sboner, Zohal Noorzad, Theresa MacDonald, Cynthia Cheung, Dong Gao, Yu Chen, Martin Eilers, Juan Miguel Mosquera, Brian D. Robinson, Mark A. Rubin, Olivier Elemento, Francesca Demichelis, David S. Rickman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 887.
https://doi.org/10.1158/1538-7445.AM2016-887
Published: 15 July 2016
View article titled, Abstract 887: N-Myc drives neuroendocrine prostate cancer
Journal Articles

Abstract 619: Personalized models to guide precision medicine

Chantal Pauli, Loredana Puca, Brooke M. Emerling, Benjamin Hopkins, Andrea Sboner, Olivier Elemento, Juan Miguel Mosquera, Himisha Beltran, Mark A. Rubin
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 619.
https://doi.org/10.1158/1538-7445.AM2016-619
Published: 15 July 2016
View article titled, Abstract 619: Personalized models to guide precision medicine
Journal Articles

Abstract 3872: Quantification of mutant SPOP proteins in prostate cancer using targeted proteomics

Hui Wang, Christopher Barbieri, Jintang He, Yuqian Gao, Chaochao Wu, Athena Schepmoes, Thomas Fillmore, Tujin Shi, Sung-Suk Chae, Dennis Huang, Juan Miguel Mosquera, Wei-Jun Qian, Richard Smith, Sudhir Srivastava, Jacob Kagan, David Camp, Karin Rodland, Mark Rubin, Tao Liu
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3872.
https://doi.org/10.1158/1538-7445.AM2016-3872
Published: 15 July 2016
View article titled, Abstract 3872: Quantification of mutant SPOP proteins in prostate cancer using targeted proteomics
Journal Articles

Abstract B41: Targeting androgen-independent prostate cancer through epigenetic reprogramming

Loredana Puca, Dong Gao, Myriam Kossai, Joanna Cyrta, Clarisse Marotz, Juan Miguel Mosquera, Theresa Y. MacDonald, Andrea Sboner, Rema Rao, Yu Chen, Mark A. Rubin, Himisha Beltran
Journal: Cancer Research
Cancer Res (2016) 76 (2_Supplement): B41.
https://doi.org/10.1158/1538-7445.CHROMEPI15-B41
Published: 14 January 2016
View article titled, Abstract B41: Targeting androgen-independent prostate cancer through epigenetic reprogramming
Journal Articles

Abstract LB-072: The N-Myc transcriptional program driving the neuroendocrine prostate cancer phenotype

Etienne Dardenne, Kaitlyn Gayvert, Adeline Berger, Andrea Sboner, Brian Robinson, Kenneth Hennrick, Juan Miguel Mosquera, Cynthia Cheung, Martin Eilers, Himisha Beltran, Mark A. Rubin, Olivier Elemento, David S. Rickman
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-072.
https://doi.org/10.1158/1538-7445.AM2015-LB-072
Published: 01 August 2015
View article titled, Abstract LB-072: The N-Myc transcriptional program driving the neuroendocrine prostate cancer phenotype
Journal Articles

Abstract 3844: Targeting EZH2 in neuroendocrine prostate cancer

Loredana Puca, Dong Gao, Myriam Kossai, Clarisse Marotz, Juan Miguel Mosquera, Theresa Y. MacDonald, Kyung Park, Rema Rao, Andrea Sboner, Yu Chen, Mark A. Rubin, Himisha Beltran
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3844.
https://doi.org/10.1158/1538-7445.AM2015-3844
Published: 01 August 2015
View article titled, Abstract 3844: Targeting EZH2 in neuroendocrine prostate cancer
Journal Articles

Abstract 4672: Development of 2D - cell strain and 3D - tumor spheroid models for Precision Medicine

Chantal Pauli, Jonathan Pauwels, Myriam Kossai, Nikolai Steklov, Andrea Sboner, Rema Rao, Kenneth Hennrick, Brian Robinson, Juan Miguel Mosquera, Himisha Beltran, Mark A. Rubin
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4672.
https://doi.org/10.1158/1538-7445.AM2015-4672
Published: 01 August 2015
View article titled, Abstract 4672: Development of 2D - cell strain and 3D - tumor spheroid models for Precision Medicine