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Abstract 2963: VB7-756: a Her2-specific diabody armed with deBouganin, a plant toxin with a distinct MOA

Shilpa Chooniedass, Rachelle L. Dillon, Arjune Premsukh, Joycelyn Entwistle, Gregory P. Adams, Peter J. Hudson, Glen C. MacDonald, Jeannick Cizeau

Cancer Res (2016) 76 (14_Supplement): 2963.

DOI: https://doi.org/10.1158/1538-7445.AM2016-2963

Published: 15 July 2016

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Journal Articles

Abstract 2961: deBouganin conjugated to trastuzumab overcomes multiple mechanisms of T-DM1 drug resistance

Rachelle L. Dillon, Shilpa Chooniedass, Arjune Premsukh, Gregory P. Adams, Joycelyn Entwistle, Glen C. MacDonald, Jeannick Cizeau

Cancer Res (2016) 76 (14_Supplement): 2961.

DOI: https://doi.org/10.1158/1538-7445.AM2016-2961

Published: 15 July 2016

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Journal Articles

Abstract #1732: Fusogenics\#8482;: A novel approach to antibody affinity maturation

Jeannick Cizeau, Danielle Grenkow, Stacy Stibbard, Arjune Premsukh, Joycelyn Entwistle, Glen MacDonald

Cancer Res (2009) 69 (9_Supplement): 1732.

Published: 01 May 2009

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Journal Articles

Pre-clinical safety assessment of VB4-845, an EpCAM binding immunoconjugate

Crystal Marlin, Jennifer Brown, Michele Rasamoelisoloa, Jeannick Cizeau, Denis Bosc, Joycelyn Entwistle, Nick Glover, Glen MacDonald

Cancer Res (2008) 68 (9_Supplement): 2136.

Published: 01 May 2008

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Journal Articles

Evaluation of the immunotoxin, Proxinium™ in combination with chemotherapy and radiotherapy

Jennifer Brown, Michele Rasamoelisolo, Jeannick Cizeau, Denis Bosc, Joycelyn Entwistle, Nick Glover, Glen MacDonald

Cancer Res (2007) 67 (9_Supplement): 4103.

Published: 01 May 2007

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Journal Articles

VB1-008: Identification of a fully-human antibody specific for CD44E and CD44-isoform-3

Jeannick Cizeau, Francina Chahal, Joycelyn Entwistle, Michele Rasamoelisolo, Nick Glover, Glen MacDonald

Cancer Res (2006) 66 (8_Supplement): 682.

Published: 15 April 2006

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Journal Articles

A truncated variant of AFP (t-AFP) that binds to VB1-008 and associates with CD44

Francina C. Chahal, Joycelyn Entwistle, Nick Glover, Glen C. MacDonald

Cancer Res (2006) 66 (8_Supplement): 808.

Published: 15 April 2006

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Journal Articles

Complete regression of ovarian cancer xenografts following treatment with the recombinant immunocytotoxic protein, VB6-845.

Jennifer G. Brown, Michele Rasamoelisolo, Jeannick Cizeau, Denis Bosc, Joycelyn Entwistle, Nick Glover, Glen MacDonald

Cancer Res (2006) 66 (8_Supplement): 1305–1306.

Published: 15 April 2006

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Journal Articles

A preclinical profile of VB6-845, a recombinant immunotoxin for targeting ovarian cancer

Jennifer G. Brown, Jeannick Cizeau, Denis Bosc, Michele Rasamoelisolo, Joycelyn Entwistle, Nick Glover, Glen MacDonald

Cancer Res (2006) 66 (8_Supplement): 278.

Published: 15 April 2006

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Journal Articles

A preclinical profile of Proxinium™, a recombinant immunotoxin for targeting head and neck cancer

Jennifer Brown, Jeannick Cizeau, Denis Bosc, Joycelyn Entwistle, Nick Glover, Glen C. MacDonald

Cancer Res (2005) 65 (9_Supplement): 162.

Published: 01 May 2005

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Journal Articles

De-immunized bouganin: an innovative, antibody-directed, cytotoxic payload for a safer and more efficacious treatment of cancer

Joycelyn Entwistle, Glen C. MacDonald, Nick Glover

Cancer Res (2005) 65 (9_Supplement): 161.

Published: 01 May 2005

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Journal Articles

Functional and biological characterization of VB6-845, a recombinant Ep-CAM-specific Fab antibody genetically-linked with de-immunized bouganin (de-bouganin)

Michele Rasamoelisolo, Jeannick Cizeau, Denis Bosc, Joycelyn Entwistle, Nick Glover, Glen C. MacDonald

Cancer Res (2005) 65 (9_Supplement): 161.

Published: 01 May 2005

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Journal Articles

VB6-845: recombinant engineering of an Ep-CAM-specific Fab antibody for optimal delivery of de-immunized bouganin (de-bouganin)

Jeannick Cizeau, Denis Bosc, Joycelyn Entwistle, Nick Glover, Glen MacDonald

Cancer Res (2005) 65 (9_Supplement): 161.

Published: 01 May 2005

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NARROW

Abstract 2963: VB7-756: a Her2-specific diabody armed with deBouganin, a plant toxin with a distinct MOA

Abstract 2961: deBouganin conjugated to trastuzumab overcomes multiple mechanisms of T-DM1 drug resistance

Abstract #1732: Fusogenics\#8482;: A novel approach to antibody affinity maturation

Pre-clinical safety assessment of VB4-845, an EpCAM binding immunoconjugate

Evaluation of the immunotoxin, Proxinium™ in combination with chemotherapy and radiotherapy

VB1-008: Identification of a fully-human antibody specific for CD44E and CD44-isoform-3

A truncated variant of AFP (t-AFP) that binds to VB1-008 and associates with CD44

Complete regression of ovarian cancer xenografts following treatment with the recombinant immunocytotoxic protein, VB6-845.

A preclinical profile of VB6-845, a recombinant immunotoxin for targeting ovarian cancer

A preclinical profile of Proxinium™, a recombinant immunotoxin for targeting head and neck cancer

De-immunized bouganin: an innovative, antibody-directed, cytotoxic payload for a safer and more efficacious treatment of cancer

Functional and biological characterization of VB6-845, a recombinant Ep-CAM-specific Fab antibody genetically-linked with de-immunized bouganin (de-bouganin)

VB6-845: recombinant engineering of an Ep-CAM-specific Fab antibody for optimal delivery of de-immunized bouganin (de-bouganin)

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