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Journal Articles

Abstract 6446: Yap1 and CD276/B7-H3: key players in Sex-biased SHH medulloblastoma immune evasion

Nourhan Abdelfattah, Sivaraman Natarajan, Han Nhat Tran, Thomas Wong, Jose Maldonado, Rachael McMinimy, Hannah Borland, Shu-hsia Chen, Fernando Camargo, James Olson, Joshy George, Kyuson Yun

Cancer Res (2025) 85 (8_Supplement_1): 6446.

https://doi.org/10.1158/1538-7445.AM2025-6446

Published: 21 April 2025

View articletitled, Abstract 6446: Yap1 and CD276/B7-H3: key players in Sex-biased SHH medulloblastoma immune evasion

Journal Articles

Abstract 3037: Sex-specific differences in Yap1 and Cd276 function and expression regulate medulloblastoma progression and immune evasion

Nourhan Abdelfattah, Sivaraman Natarajan, Han Nhat Tran, Jose Maldonado, Rachael McMinimy, Hannah Borland, Shu-hsia Chen, Fernando Camargo, James Olson, Joshy George, Kyuson Yun

Cancer Res (2024) 84 (6_Supplement): 3037.

https://doi.org/10.1158/1538-7445.AM2024-3037

Published: 22 March 2024

View articletitled, Abstract 3037: Sex-specific differences in Yap1 and Cd276 function and expression regulate medulloblastoma progression and immune evasion

Journal Articles

Abstract 5871: Pan-cancer myeloid cell analysis at the single cell level reveals the influence of distinct organ sites in myeloid cell phenotypes and support targeting S100A4 to reverse immune suppression

Cancer Res (2023) 83 (7_Supplement): 5871.

https://doi.org/10.1158/1538-7445.AM2023-5871

Published: 04 April 2023

View articletitled, Abstract 5871: Pan-cancer myeloid cell analysis at the single cell level reveals the influence of distinct organ sites in myeloid cell phenotypes and support targeting S100A4 to reverse immune suppression

Journal Articles

Abstract 1708: Sex-biased function of an oncogene, YAP1, regulates medulloblastoma stem cells and immune evasion

Nourhan Abdelfattah, Sivaraman Natarajan, Jose Maldonado, Han Nhat Tran, Hannah Borland, Rachael McMinimy, Shu-Hsia Chen, Fernando Camargo, James Olson, Joshy George, Kyuson Yun

Cancer Res (2023) 83 (7_Supplement): 1708.

https://doi.org/10.1158/1538-7445.AM2023-1708

Published: 04 April 2023

View articletitled, Abstract 1708: Sex-biased function of an oncogene, YAP1, regulates medulloblastoma stem cells and immune evasion

Journal Articles

Abstract P1-13-10: Deconvoluting dynamics of acquired chemoresistance in Triple Negative Breast Cancer tumors

Pooja Kumar, Francesca Menghi, Robert Straub, Patience Mukashyaka, Michael W. Lloyd, Harshpreet Chandok, Joshy George, Jeffery Chuang, Edison Liu

Cancer Res (2023) 83 (5_Supplement): P1-13-10.

https://doi.org/10.1158/1538-7445.SABCS22-P1-13-10

Published: 01 March 2023

View articletitled, Abstract P1-13-10: Deconvoluting dynamics of acquired chemoresistance in Triple Negative Breast Cancer tumors

Journal Articles

A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non–Small Cell Lung Cancer

Cancer Res (2022) 82 (22): 4126–4138.

https://doi.org/10.1158/0008-5472.CAN-22-0948

Published: 15 November 2022

View articletitled, A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non–Small Cell Lung Cancer

Includes: Supplementary data

Journal Articles

Abstract 2540: A multi-dimensional analysis of human gliomas at the single cell level identifies immune suppressive macrophage molecular signatures and a novel immunotherapy target for GBM

Cancer Res (2022) 82 (12_Supplement): 2540.

https://doi.org/10.1158/1538-7445.AM2022-2540

Published: 15 June 2022

View articletitled, Abstract 2540: A multi-dimensional analysis of human gliomas at the single cell level identifies immune suppressive macrophage molecular signatures and a novel immunotherapy target for GBM

Journal Articles

Abstract 3961: Cancer stem cells, not bulk tumor cells, predict mechanisms of resistance to SMO inhibitors in SHH medulloblastoma

Joshy George, Yaohui Chen, Nourhan Abdelfattah, Keiko Yamamoto, Scott Adamson, Jong Min Choi, Brad Rybinski, Anuj Srivastava, Parveen Kumar, Min Gyu Lee, David S. Baskin, Wen Jiang, Betty Y. Kim, William Flavahan, Jeffrey H. Chuang, Sung Yun Jung, Kyuson Yun

Cancer Res (2022) 82 (12_Supplement): 3961.

https://doi.org/10.1158/1538-7445.AM2022-3961

Published: 15 June 2022

View articletitled, Abstract 3961: Cancer stem cells, not bulk tumor cells, predict mechanisms of resistance to SMO inhibitors in SHH medulloblastoma

Journal Articles

Abstract 1331: Elucidating cell-to-cell communication and immunotherapy responses in deeply characterized mouse models of human glioma subtypes

Caiyi Wang, Jose Maldonado, Thomas D. Gallup, Nourhan Abdelfattah, Jia-Shiun Leu, Nithin Joshy, joshy George, Jihye Paik, Massimo Squatrito, Kyuson Yun

Cancer Res (2022) 82 (12_Supplement): 1331.

https://doi.org/10.1158/1538-7445.AM2022-1331

Published: 15 June 2022

View articletitled, Abstract 1331: Elucidating cell-to-cell communication and immunotherapy responses in deeply characterized mouse models of human glioma subtypes

Journal Articles

Abstract P5-01-05: Transcriptional signature of metastatic triple negative breast cancer in humanized mice

Chun I Yu, Te-Chia Wu, Francesca Menghi, Joshy George, Kyung In Kim, Florentina Marches, Edison T Liu, Jacques Banchereau, Karolina Palucka

Cancer Res (2022) 82 (4_Supplement): P5-01-05.

https://doi.org/10.1158/1538-7445.SABCS21-P5-01-05

Published: 15 February 2022

View articletitled, Abstract P5-01-05: Transcriptional signature of metastatic triple negative breast cancer in humanized mice

Journal Articles

Abstract 1750: Human KIT⁺myeloid cells facilitate visceral organ colonization by melanoma

Chun I. Yu, Jan Martinek, Te-Chia Wu, Kyung In Kim, Joshy George, Elaheh Ahmadzadeh, Rick Maser, Florentina Marches, Patrick Metang, Pierre Authie, Vanessa K. Oliveira, Victor G. Wang, Jeffrey H. Chuang, Paul Robson, Jacques Banchereau, Karolina Palucka

Cancer Res (2021) 81 (13_Supplement): 1750.

https://doi.org/10.1158/1538-7445.AM2021-1750

Published: 01 July 2021

View articletitled, Abstract 1750: Human KIT+myeloid cells facilitate visceral organ colonization by melanoma

Journal Articles

Abstract 3441: Transcriptional profiles of CD14+ cells in situ in melanoma reveal plasticity, localization dependent function and specific T cell interactions

Jan Martinek, Kyung In Kim, Jianan Lin, Te-Chia Wu, Hannah Borouchov, Ananya Gulati, Lili Sun, Victor Wang, Joshy George, Philipp Henrich, Florentina Marches, Anthony Rongvaux, Michael Chiorazzi, Jeffrey H. Chuang, Paul Robson, Richard Flavell, Jacques Banchereau, Karolina Palucka

Cancer Res (2020) 80 (16_Supplement): 3441.

https://doi.org/10.1158/1538-7445.AM2020-3441

Published: 15 August 2020

View articletitled, Abstract 3441: Transcriptional profiles of CD14+ cells in situ in melanoma reveal plasticity, localization dependent function and specific T cell interactions

Journal Articles

Abstract 1075: Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): Challenges and guidelines

Xing Yi Woo, Anuj Srivastava, Joel H. Graber, Vinod Yadav, Vishal Kumar Sarsani, Al Simons, Glen Beane, Stephen Grubb, Guruprasad Ananda, Grace Stafford, Jeffrey H. Chuang, Susan D. Airhart, R. Krishna Karuturi, Joshy George, Carol J. Bult

Cancer Res (2019) 79 (13_Supplement): 1075.

https://doi.org/10.1158/1538-7445.AM2019-1075

Published: 01 July 2019

View articletitled, Abstract 1075: Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): Challenges and guidelines

Journal Articles

Abstract 1507: Transcriptional profiles of CD14+ cells in situ in melanoma tumors reveal plasticity and localization dependent function

Jan Martinek, Kyung In Kim, Te-Chia Wu, Victor Wang, Hannah M. Brookes, Lili Sun, Ananya Gulati, Joshy George, Philipp Henrich, Florentina Marches, Anthony Rongvaux, Michael Chiorazzi, Jeff Chuang, Paul Robson, Richard Flavell, Jacques Banchereau, Karolina Palucka

Cancer Res (2019) 79 (13_Supplement): 1507.

https://doi.org/10.1158/1538-7445.AM2019-1507

Published: 01 July 2019

View articletitled, Abstract 1507: Transcriptional profiles of CD14+ cells in situ in melanoma tumors reveal plasticity and localization dependent function

Journal Articles

IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer

Cancer Res (2018) 78 (18): 5243–5258.

https://doi.org/10.1158/0008-5472.CAN-18-0413

Published: 14 September 2018

View articletitled, IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer

Includes: Supplementary data

Journal Articles

Abstract 165: Cancer stem cell phenotypes determine mechanisms of resistance to targeted therapies

Joshy George, Yaohui Chen, Keiko Yamamoto, Scott Adamson, Jeff Chuang, Kyuson Yun

Cancer Res (2018) 78 (13_Supplement): 165.

https://doi.org/10.1158/1538-7445.AM2018-165

Published: 01 July 2018

View articletitled, Abstract 165: Cancer stem cell phenotypes determine mechanisms of resistance to targeted therapies

Journal Articles

Abstract 5680: Quantitative cellular and molecular imaging of the intact tumor microenvironment

Jan Martinek, Hannah M. Brookes, Te-chia Wu, Lili Sun, Philipp Henrich, Kyung In Kim, Joshy George, Paul Robson, Jacques Banchereau, Karolina Palucka

Cancer Res (2018) 78 (13_Supplement): 5680.

https://doi.org/10.1158/1538-7445.AM2018-5680

Published: 01 July 2018

View articletitled, Abstract 5680: Quantitative cellular and molecular imaging of the intact tumor microenvironment

Journal Articles

S100A4 Is a Biomarker and Regulator of Glioma Stem Cells That Is Critical for Mesenchymal Transition in Glioblastoma

Kin-Hoe Chow, Hee Jung Park, Joshy George, Keiko Yamamoto, Andrew D. Gallup, Joel H. Graber, Yuanxin Chen, Wen Jiang, Dennis A. Steindler, Eric G. Neilson, Betty Y.S. Kim, Kyuson Yun

Cancer Res (2017) 77 (19): 5360–5373.

https://doi.org/10.1158/0008-5472.CAN-17-1294

Published: 01 October 2017

View articletitled, S100A4 Is a Biomarker and Regulator of Glioma Stem Cells That Is Critical for Mesenchymal Transition in Glioblastoma

Includes: Supplementary data

Journal Articles

EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas

Cancer Res (2017) 77 (16): 4268–4278.

https://doi.org/10.1158/0008-5472.CAN-16-2224

Published: 14 August 2017

View articletitled, EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas

Includes: Supplementary data

Journal Articles

Abstract 4783: Regulation of GBM stemness and mesenchymal transition

Kin-Hoe Chow, Hee Jung Park, Joshy George, Yuanxin Chen, Andrew Gallup, Wen Jiang, Betty Y. Kim, Kyuson Yun

Cancer Res (2017) 77 (13_Supplement): 4783.

https://doi.org/10.1158/1538-7445.AM2017-4783

Published: 01 July 2017

View articletitled, Abstract 4783: Regulation of GBM stemness and mesenchymal transition

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Abstract 6446: Yap1 and CD276/B7-H3: key players in Sex-biased SHH medulloblastoma immune evasion

Abstract 3037: Sex-specific differences in Yap1 and Cd276 function and expression regulate medulloblastoma progression and immune evasion

Abstract 5871: Pan-cancer myeloid cell analysis at the single cell level reveals the influence of distinct organ sites in myeloid cell phenotypes and support targeting S100A4 to reverse immune suppression

Abstract 1708: Sex-biased function of an oncogene, YAP1, regulates medulloblastoma stem cells and immune evasion

Abstract P1-13-10: Deconvoluting dynamics of acquired chemoresistance in Triple Negative Breast Cancer tumors

A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non–Small Cell Lung Cancer

Abstract 2540: A multi-dimensional analysis of human gliomas at the single cell level identifies immune suppressive macrophage molecular signatures and a novel immunotherapy target for GBM

Abstract 3961: Cancer stem cells, not bulk tumor cells, predict mechanisms of resistance to SMO inhibitors in SHH medulloblastoma

Abstract 1331: Elucidating cell-to-cell communication and immunotherapy responses in deeply characterized mouse models of human glioma subtypes

Abstract P5-01-05: Transcriptional signature of metastatic triple negative breast cancer in humanized mice

Abstract 1750: Human KIT⁺myeloid cells facilitate visceral organ colonization by melanoma

Abstract 3441: Transcriptional profiles of CD14+ cells in situ in melanoma reveal plasticity, localization dependent function and specific T cell interactions

Abstract 1075: Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): Challenges and guidelines

Abstract 1507: Transcriptional profiles of CD14+ cells in situ in melanoma tumors reveal plasticity and localization dependent function

IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer

Abstract 165: Cancer stem cell phenotypes determine mechanisms of resistance to targeted therapies

Abstract 5680: Quantitative cellular and molecular imaging of the intact tumor microenvironment

S100A4 Is a Biomarker and Regulator of Glioma Stem Cells That Is Critical for Mesenchymal Transition in Glioblastoma

EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas

Abstract 4783: Regulation of GBM stemness and mesenchymal transition

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