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Joshua M. Korn
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Journal Articles

Abstract 896: Predicting metastatic transcriptomes of patient tumors with deep learning

Gang Li, Evan Béal, Dean Sumner, Giorgio G. Galli, Viviana Cremasco, Joshua M. Korn, Frank Dondelinger, David Ruddy, Audrey Kauffmann, Slavica Dimitrieva
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 896.
https://doi.org/10.1158/1538-7445.AM2024-896
Published: 22 March 2024
View article titled, Abstract 896: Predicting metastatic transcriptomes of patient tumors with deep learning
Journal Articles

Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance

Jennifer L. Cotton, Javier Estrada Diez, Vivek Sagar, Julie Chen, Michelle Piquet, John Alford, Youngchul Song, Xiaoyan Li, Markus Riester, Matthew T. DiMare, Katja Schumacher, Gaylor Boulay, Kathleen Sprouffske, Lin Fan, Tyler Burks, Leandra Mansur, Joel Wagner, Hyo-eun C. Bhang, Oleg Iartchouk, John Reece-Hoyes, Erick J. Morris, Peter S. Hammerman, David A. Ruddy, Joshua M. Korn, Jeffrey A. Engelman, Matthew J. Niederst
Journal: Cancer Research
Cancer Res (2023) 83 (21): 3611–3623.
https://doi.org/10.1158/0008-5472.CAN-23-0144
Published: 01 November 2023
View article titled, Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance
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Includes: Supplementary data
Journal Articles

A Proof of Concept for Biomarker-Guided Targeted Therapy against Ovarian Cancer Based on Patient-Derived Tumor Xenografts

Adam C. Palmer, Deborah Plana, Hui Gao, Joshua M. Korn, Guizhi Yang, John Green, Xiamei Zhang, Roberto Velazquez, Margaret E. McLaughlin, David A. Ruddy, Colleen Kowal, Julie Muszynski, Caroline Bullock, Stacy Rivera, Daniel P. Rakiec, GiNell Elliott, Paul Fordjour, Ronald Meyer, Alice Loo, Esther Kurth, Jeffrey A. Engelman, Hans Bitter, William R. Sellers, Juliet A. Williams, Peter K. Sorger
Journal: Cancer Research
Cancer Res (2020) 80 (19): 4278–4287.
https://doi.org/10.1158/0008-5472.CAN-19-3850
Published: 02 October 2020
View article titled, A Proof of Concept for Biomarker-Guided Targeted Therapy against Ovarian Cancer Based on Patient-Derived Tumor Xenografts
Open the PDF for A Proof of Concept for Biomarker-Guided Targeted Therapy against Ovarian Cancer Based on Patient-Derived Tumor Xenografts in another window
Includes: Supplementary data
Journal Articles

Abstract 394: In vivo shRNA screens under treatment pressure by BRAF and MEK inhibitors to identify novel combination treatment strategies for BRAF-mutant colorectal cancer

Hyo-eun C. Bhang, Matthew T. DiMare, David P. Kodack, Lujian Tan, Grainne Kerr, Viveksagar Krishnamurthy Radhakrishna, Javad Golji, David A. Ruddy, Tina Yuan, Matthew J. Niederst, Joshua M. Korn, Diana Graus Porta, Peter S. Hammerman, Jeffrey A. Engelman, Tinya Abrams, Juliet Williams
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 394.
https://doi.org/10.1158/1538-7445.AM2019-394
Published: 01 July 2019
View article titled, Abstract 394: <em>In vivo</em> shRNA screens under treatment pressure by BRAF and MEK inhibitors to identify novel combination treatment strategies for <em>BRAF</em>-mutant colorectal cancer
Journal Articles

Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF

Wenlin Shao, Yuji M. Mishina, Yun Feng, Giordano Caponigro, Vesselina G. Cooke, Stacy Rivera, Yingyun Wang, Fang Shen, Joshua M. Korn, Lesley A. Mathews Griner, Gisele Nishiguchi, Alice Rico, John Tellew, Jacob R. Haling, Robert Aversa, Valery Polyakov, Richard Zang, Mohammad Hekmat-Nejad, Payman Amiri, Mallika Singh, Nicholas Keen, Michael P. Dillon, Emma Lees, Savithri Ramurthy, William R. Sellers, Darrin D. Stuart
Journal: Cancer Research
Cancer Res (2018) 78 (6): 1537–1548.
https://doi.org/10.1158/0008-5472.CAN-17-2033
Published: 14 March 2018
View article titled, Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF
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Includes: Supplementary data
Journal Articles

Abstract 3240: Understanding clonal complexity of a tumor xenograft model via cellular barcoding technology

Justina X. Caushi, Hyo-eun C. Bhang, Jie Li, Iris Kao, Viveksagar Krishnamurthy Radhakrishna, Vesselina G. Cooke, Joshua M. Korn, David A. Ruddy, Shailaja Kasibhatla, Frank Stegmeier
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3240.
https://doi.org/10.1158/1538-7445.AM2015-3240
Published: 01 August 2015
View article titled, Abstract 3240: Understanding clonal complexity of a tumor xenograft model via cellular barcoding technology
Journal Articles

Abstract 2847: High complexity barcoding to study clonal dynamics in response to cancer therapy

Hyo-eun C. Bhang, David A. Ruddy, Viveksagar Krishnamurthy Radhakrishna, Rui Zhao, Iris Kao, Daniel Rakiec, Pamela Shaw, Marissa Balak, Justina X. Caushi, Elizabeth Ackley, Nicholas Keen, Michael R. Schlabach, Michael Palmer, William R. Sellers, Franziska Michor, Vesselina G. Cooke, Joshua M. Korn, Frank Stegmeier
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2847.
https://doi.org/10.1158/1538-7445.AM2015-2847
Published: 01 August 2015
View article titled, Abstract 2847: High complexity barcoding to study clonal dynamics in response to cancer therapy
Journal Articles

Inhibiting Tankyrases Sensitizes KRAS-Mutant Cancer Cells to MEK Inhibitors via FGFR2 Feedback Signaling

Marie Schoumacher, Kristen E. Hurov, Joseph Lehár, Yan Yan-Neale, Yuji Mishina, Dmitriy Sonkin, Joshua M. Korn, Daisy Flemming, Michael D. Jones, Brandon Antonakos, Vesselina G. Cooke, Janine Steiger, Jebediah Ledell, Mark D. Stump, William R. Sellers, Nika N. Danial, Wenlin Shao
Journal: Cancer Research
Cancer Res (2014) 74 (12): 3294–3305.
https://doi.org/10.1158/0008-5472.CAN-14-0138-T
Published: 12 June 2014
View article titled, Inhibiting Tankyrases Sensitizes KRAS-Mutant Cancer Cells to MEK Inhibitors via FGFR2 Feedback Signaling
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Includes: Supplementary data