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Joshua A. McCarroll
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Journal Articles

Abstract B076: βIII-Tubulin is a brake on extrinsic cell-death in pancreatic cancer

John Kokkinos, George Sharbeen, Janet Youkhana, Cyrille Boyer, David Goldstein, Koroush S. Haghighi, Joshua A. McCarroll, Phoebe A. Phillips
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): B076.
https://doi.org/10.1158/1538-7445.PANCA22-B076
Published: 15 November 2022
View articletitled, Abstract B076: βIII-Tubulin is a brake on extrinsic cell-death in pancreatic cancer
Journal Articles

Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition

George Sharbeen, Joshua A. McCarroll, Anouschka Akerman, Chantal Kopecky, Janet Youkhana, John Kokkinos, Jeff Holst, Cyrille Boyer, Mert Erkan, David Goldstein, Paul Timpson, Thomas R. Cox, Brooke A. Pereira, Jessica L. Chitty, Sigrid K. Fey, Arafath K. Najumudeen, Andrew D. Campbell, Owen J. Sansom, Rosa Mistica C. Ignacio, Stephanie Naim, Jie Liu, Nelson Russia, Julia Lee, Angela Chou, Amber Johns, Anthony J. Gill, Estrella Gonzales-Aloy, Val Gebski, Yi Fang Guan, Marina Pajic, Nigel Turner, Minoti V. Apte, Thomas P. Davis, Jennifer P. Morton, Koroush S. Haghighi, Jorjina Kasparian, Benjamin J. McLean, Yordanos F. Setargew, Phoebe A. Phillips
Journal: Cancer Research
Series: Author Choice
Cancer Res (2021) 81 (13): 3461–3479.
https://doi.org/10.1158/0008-5472.CAN-20-2496
Published: 01 July 2021
View articletitled, Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition
Open the PDF for Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition in another window
Includes: Supplementary data
Journal Articles

Abstract 1442: Identifying the molecular basis by which βIII-tubulin promotes tumor cell survival and drug resistance in non-small cell lung cancer

Simon Brayford, Wee Siang Teo, Amelia Parker, Laura McVeigh, Joshua A. McCarroll, Maria Kavallaris
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1442.
https://doi.org/10.1158/1538-7445.AM2020-1442
Published: 15 August 2020
View articletitled, Abstract 1442: Identifying the molecular basis by which βIII-tubulin promotes tumor cell survival and drug resistance in non-small cell lung cancer
Journal Articles

Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface

Jessica Koach, Jessica K. Holien, Hassina Massudi, Daniel R. Carter, Olivia C. Ciampa, Mika Herath, Taylor Lim, Janith A. Seneviratne, Giorgio Milazzo, Jayne E. Murray, Joshua A. McCarroll, Bing Liu, Chelsea Mayoh, Bryce Keenan, Brendan W. Stevenson, Michael A. Gorman, Jessica L. Bell, Larissa Doughty, Stefan Hüttelmaier, Andre Oberthuer, Matthias Fischer, Andrew J. Gifford, Tao Liu, Xiaoling Zhang, Shizhen Zhu, W. Clay Gustafson, Michelle Haber, Murray D. Norris, Jamie I. Fletcher, Giovanni Perini, Michael W. Parker, Belamy B. Cheung, Glenn M. Marshall
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (21): 5652–5667.
https://doi.org/10.1158/0008-5472.CAN-19-1112
Published: 01 November 2019
View articletitled, Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface
Open the PDF for Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface in another window
Includes: Supplementary data
Journal Articles

Abstract 5484: Structural domains of βIII-Tubulin regulate multiple stress responses and influence cell growth and survival in glucose-deprived non-small cell lung cancer

Amelia L. Parker, Wee S. Teo, Joshua A. McCarroll, Maria Kavallaris
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5484.
https://doi.org/10.1158/1538-7445.AM2017-5484
Published: 01 July 2017
View articletitled, Abstract 5484: Structural domains of βIII-Tubulin regulate multiple stress responses and influence cell growth and survival in glucose-deprived non-small cell lung cancer
Journal Articles

Abstract 4037: High throughput kinase inhibitor screen reveals novel inhibitor combinations acting in synergy with TUBB3/βIII-tubulin suppression in non-small cell lung cancer

Wee Siang Teo, Tanya Dwarte, Tim W. Failes, Greg M. Arndt, Joshua A. McCarroll, Maria Kavallaris
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4037.
https://doi.org/10.1158/1538-7445.AM2017-4037
Published: 01 July 2017
View articletitled, Abstract 4037: High throughput kinase inhibitor screen reveals novel inhibitor combinations acting in synergy with TUBB3/βIII-tubulin suppression in non-small cell lung cancer
Journal Articles

TUBB3/βIII-Tubulin Acts through the PTEN/AKT Signaling Axis to Promote Tumorigenesis and Anoikis Resistance in Non–Small Cell Lung Cancer

Joshua A. McCarroll, Pei Pei Gan, Rafael B. Erlich, Marjorie Liu, Tanya Dwarte, Sharon S. Sagnella, Mia C. Akerfeldt, Lu Yang, Amelia L. Parker, Melissa H. Chang, Michael S. Shum, Frances L. Byrne, Maria Kavallaris
Journal: Cancer Research
Cancer Res (2015) 75 (2): 415–425.
https://doi.org/10.1158/0008-5472.CAN-14-2740
Published: 14 January 2015
View articletitled, TUBB3/βIII-Tubulin Acts through the PTEN/AKT Signaling Axis to Promote Tumorigenesis and Anoikis Resistance in Non–Small Cell Lung Cancer
Open the PDF for TUBB3/βIII-Tubulin Acts through the PTEN/AKT Signaling Axis to Promote Tumorigenesis and Anoikis Resistance in Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 326: βIII-Tubulin and cell survival: Novel role in endoplasmic reticulum stress and autophagy in non-small cell lung cancer

Amelia Parker, Joshua A. McCarroll, Maria Kavallaris
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 326.
https://doi.org/10.1158/1538-7445.AM2014-326
Published: 01 October 2014
View articletitled, Abstract 326: βIII-Tubulin and cell survival: Novel role in endoplasmic reticulum stress and autophagy in non-small cell lung cancer
Journal Articles

Abstract 4987: Stathmin regulates cell migration, invasion and transendothelial migration via RhoA activation in neuroblastoma

Christopher M. Fife, Frances L. Byrne, Sharon M. Sagnella, Thomas P. Davis, Joshua A. McCarroll, Maria Kavallaris
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4987.
https://doi.org/10.1158/1538-7445.AM2014-4987
Published: 01 October 2014
View articletitled, Abstract 4987: Stathmin regulates cell migration, invasion and transendothelial migration via RhoA activation in neuroblastoma
Journal Articles

Abstract 2076: βIII-tubulin is required for the tumorigenic phenotype and resistance to anoikis via the PTEN/AKT signaling axis in non-small cell lung cancer

Joshua A. McCarroll, Pei Pei Gan, Rafael B. Erlich, Marjorie Liu, Tanya Dwarte, Mia C. Akerfeldt, Melissa Chang, Michael S. Shum, Frances Byrne, Maria Kavallaris
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2076.
https://doi.org/10.1158/1538-7445.AM2014-2076
Published: 01 October 2014
View articletitled, Abstract 2076: βIII-tubulin is required for the tumorigenic phenotype and resistance to anoikis via the PTEN/AKT signaling axis in non-small cell lung cancer
Journal Articles

Abstract 1969: Silencing αIII-tubulin by RNA interfering nanoparticles in non-small cell lung cancer

Joshua A. Mccarroll, Huricha Baigude, Rafael Erlich, Tanya Dwarte, Tariq M. Rana, Maria Kavallaris
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1969.
https://doi.org/10.1158/1538-7445.AM2012-1969
Published: 15 April 2012
View articletitled, Abstract 1969: Silencing αIII-tubulin by RNA interfering nanoparticles in non-small cell lung cancer
Journal Articles

Abstract 1444: Stathmin suppression influences ROCK signaling and reduces cell invasion and metastasis in neuroblastoma

Frances L. Byrne, Phoebe A. Phillips, Loen M. Hansford, Jamie I. Fletcher, Christopher J. Ormandy, Joshua A. McCarroll, Maria Kavallaris
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1444.
https://doi.org/10.1158/1538-7445.AM2012-1444
Published: 15 April 2012
View articletitled, Abstract 1444: Stathmin suppression influences ROCK signaling and reduces cell invasion and metastasis in neuroblastoma
Journal Articles

βIII-Tubulin Is a Multifunctional Protein Involved in Drug Sensitivity and Tumorigenesis in Non–Small Cell Lung Cancer

Joshua A. McCarroll, Pei Pei Gan, Marjorie Liu, Maria Kavallaris
Journal: Cancer Research
Cancer Res (2010) 70 (12): 4995–5003.
https://doi.org/10.1158/0008-5472.CAN-09-4487
Published: 14 June 2010
View articletitled, βIII-Tubulin Is a Multifunctional Protein Involved in Drug Sensitivity and Tumorigenesis in Non–Small Cell Lung Cancer
Open the PDF for βIII-Tubulin Is a Multifunctional Protein Involved in Drug Sensitivity and Tumorigenesis in Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 5026: βIII-Tubulin regulates expression of proteins involved in tumorigenesis and metastasis in non-small cell lung cancer

Joshua A. McCarroll, Pei Pei Gan, Marjorie Liu, Tanya Dwarte, Melissa Chang, Frances Byrne, Maria Kavallaris
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5026.
https://doi.org/10.1158/1538-7445.AM10-5026
Published: 15 April 2010
View articletitled, Abstract 5026: βIII-Tubulin regulates expression of proteins involved in tumorigenesis and metastasis in non-small cell lung cancer
Journal Articles

Triptolide Induces Pancreatic Cancer Cell Death via Inhibition of Heat Shock Protein 70

Phoebe A. Phillips, Vikas Dudeja, Joshua A. McCarroll, Daniel Borja-Cacho, Rajinder K. Dawra, William E. Grizzle, Selwyn M. Vickers, Ashok K. Saluja
Journal: Cancer Research
Cancer Res (2007) 67 (19): 9407–9416.
https://doi.org/10.1158/0008-5472.CAN-07-1077
Published: 01 October 2007
View articletitled, Triptolide Induces Pancreatic Cancer Cell Death via Inhibition of Heat Shock Protein 70
Open the PDF for Triptolide Induces Pancreatic Cancer Cell Death via Inhibition of Heat Shock Protein 70 in another window