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Josephine Mun Yee Ko
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Journal Articles

Abstract 3005: Low-density lipoprotein receptor-related protein 1B (LRP1B) depletion promotes tumorigenicity by modulating fibroblasts in the tumor microenvironment in esophageal squamous cell carcinoma

KaiYan Xu, Josephine Mun-yee KO, Valen Zhuo you Yu, Maria Li LUNG
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3005.
https://doi.org/10.1158/1538-7445.AM2024-3005
Published: 22 March 2024
View article titled, Abstract 3005: <em>Low-density lipoprotein receptor-related protein 1B</em> (<em>LRP1B</em>) depletion promotes tumorigenicity by modulating fibroblasts in the tumor microenvironment in esophageal squamous cell carcinoma
Journal Articles

Abstract 6705: Molecular detection of circulating cancer cells with cancer stem cell or mesenchymal characteristics in esophageal squamous cell carcinoma

Zhen Tan, Josephine Mun-Yee Ko, Valen Zhuoyou Yu, Hoi Yan Ng, Simon Law, Maria Li Lung
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6705.
https://doi.org/10.1158/1538-7445.AM2023-6705
Published: 04 April 2023
View article titled, Abstract 6705: Molecular detection of circulating cancer cells with cancer stem cell or mesenchymal characteristics in esophageal squamous cell carcinoma
Journal Articles

Abstract 1359: Characterisation of heterogeneity of esophageal squamous cell carcinoma ecosystem by single-cell transcriptomics analysis

Carissa Wing-Yan Wong, Josephine Mun-Yee Ko, Hoi Yan Ng, Valen Zhuoyou Yu, Simon Law, Maria Li Lung
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1359.
https://doi.org/10.1158/1538-7445.AM2023-1359
Published: 04 April 2023
View article titled, Abstract 1359: Characterisation of heterogeneity of esophageal squamous cell carcinoma ecosystem by single-cell transcriptomics analysis
Journal Articles

Abstract 4734: Nasopharyngeal carcinoma molecular subgroups for somatic copy number alterations (SCNAs)

Wei Dai, Dittman Lai-Shun Chung, Larry Ka-Yue Chow, Merrin Man-Long Leong, Candy King-Chi Chan, Josephine Mun-Yee Ko, Maria Li Lung
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4734.
https://doi.org/10.1158/1538-7445.AM2020-4734
Published: 15 August 2020
View article titled, Abstract 4734: Nasopharyngeal carcinoma molecular subgroups for somatic copy number alterations (SCNAs)
Journal Articles

Abstract 174: Functional characterization of ZNF750 in esophageal squamous cell carcinoma

Sheyne SA Choi, Valen Zhuoyou Yu, Josephine Mun-Yee Ko, Wei Dai, Maria L. Lung
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 174.
https://doi.org/10.1158/1538-7445.AM2019-174
Published: 01 July 2019
View article titled, Abstract 174: Functional characterization of <em>ZNF750</em> in esophageal squamous cell carcinoma
Journal Articles

Abstract 5099: Evaluation of two next-generation sequencing platforms for genomic analysis in circulating tumor cells

Chi Shan Candy Lam, Wei Dai, Josephine Mun Yee Ko, Maria Lung
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5099.
https://doi.org/10.1158/1538-7445.AM2019-5099
Published: 01 July 2019
View article titled, Abstract 5099: Evaluation of two next-generation sequencing platforms for genomic analysis in circulating tumor cells
Journal Articles

Abstract 1357: Functional characterization of FANCD2 in esophageal squamous cell carcinoma

Lisa Chan Lei, Valen Zhuoyou Yu, Lvwen Ning, Josephine Mun-Yee Ko, Li Dong Wang, Maria Li Lung
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1357.
https://doi.org/10.1158/1538-7445.AM2018-1357
Published: 01 July 2018
View article titled, Abstract 1357: Functional characterization of FANCD2 in esophageal squamous cell carcinoma
Journal Articles

Abstract 327: Functional characterization of RAD50 germline deleterious variants identified from deep targeted sequencing study of familial esophageal squamous cell carcinoma

Shiu Yeung Lam, Lvwen Ning, Hoi Yan Ng, Maria Li Lung, Josephine Mun-Yee Ko
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 327.
https://doi.org/10.1158/1538-7445.AM2018-327
Published: 01 July 2018
View article titled, Abstract 327: Functional characterization of <em>RAD50</em> germline deleterious variants identified from deep targeted sequencing study of familial esophageal squamous cell carcinoma
Journal Articles

Abstract 423: Investigating the germline deleterious rare variants for genetic susceptibility of esophagus squamous cell carcinomas by target sequencing

Lvwen Ning, Josephine Mun Yee Ko, Lisa Chan Lei, Li Dong Wang, Maria Li Lung
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 423.
https://doi.org/10.1158/1538-7445.AM2018-423
Published: 01 July 2018
View article titled, Abstract 423: Investigating the germline deleterious rare variants for genetic susceptibility of esophagus squamous cell carcinomas by target sequencing
Journal Articles

Abstract 439: Elucidation of genetic susceptibility in nasopharyngeal carcinoma (NPC) by next-generation sequencing

Wei Dai, Josephine Mun Yee Ko, Bianca Hoi Yan Ng, Hong Zheng, Maria Li Lung
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 439.
https://doi.org/10.1158/1538-7445.AM2018-439
Published: 01 July 2018
View article titled, Abstract 439: Elucidation of genetic susceptibility in nasopharyngeal carcinoma (NPC) by next-generation sequencing
Journal Articles

Abstract 1158: Differential expression and functional impact of the alternatively spliced transcripts of Extracellular matrix protein 1 in esophageal squamous cell carcinoma

Valen Zhuoyou YU, Josephine Mun-Yee Ko, Simon Law, Li Dong Wang, Maria Li Lung
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1158.
https://doi.org/10.1158/1538-7445.AM2016-1158
Published: 15 July 2016
View article titled, Abstract 1158: Differential expression and functional impact of the alternatively spliced transcripts of Extracellular matrix protein 1 in esophageal squamous cell carcinoma
Journal Articles

Abstract 5234: Rare deleterious germline mutations of candidate genes associated with risk of familial esophageal squamous cell carcinoma (ESCC) by targeted sequencing

Josephine Mun Yee Ko, Lu wen Ni, Sheyne, Sta Ana Choi, Lisa Chan Lei, Li Dong Wang, Maria Li Lung
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5234.
https://doi.org/10.1158/1538-7445.AM2016-5234
Published: 15 July 2016
View article titled, Abstract 5234: Rare deleterious germline mutations of candidate genes associated with risk of familial esophageal squamous cell carcinoma (ESCC) by targeted sequencing
Journal Articles

Abstract 4773: Aberrant methylation at chromosome 6p as novel biomarkers for diagnosis and prognosis of nasopharyngeal carcinoma

Wei Dai, Arthur Kwok Leung Cheung, Josephine Mun Yee Ko, Hong Zheng, Yue Cheng, Roger Kai Cheong Ngan, Wai Tong Ng, Anne Wing Mui Lee, Chun Chung Yau, Victor Ho Fu Lee, Maria Li Lung
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4773.
https://doi.org/10.1158/1538-7445.AM2015-4773
Published: 01 August 2015
View article titled, Abstract 4773: Aberrant methylation at chromosome 6p as novel biomarkers for diagnosis and prognosis of nasopharyngeal carcinoma
Journal Articles

Abstract 1280: Germline PALB2 genetic variations of familial esophageal squamous cell carcinoma (ESCC) in Henan, a high risk ESCC region

Josephine Mun Yee Ko, Li Dong Wang, Maria Lung
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1280.
https://doi.org/10.1158/1538-7445.AM2014-1280
Published: 01 October 2014
View article titled, Abstract 1280: Germline PALB2 genetic variations of familial esophageal squamous cell carcinoma (ESCC) in Henan, a high risk ESCC region
Journal Articles

Abstract 2181: Characterization of PHF11, a candidate tumor suppressor gene, in esophageal squamous cell carcinoma

Wai Ying Cheung, Josephine Mun Yee Ko, Zhuoyou Yu, Maria Li Lung
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2181.
https://doi.org/10.1158/1538-7445.AM2012-2181
Published: 15 April 2012
View article titled, Abstract 2181: Characterization of PHF11, a candidate tumor suppressor gene, in esophageal squamous cell carcinoma
Journal Articles

Abstract 420: Physiological β-catenin signaling regulates pluripotency genes in cancer microcell hybrids

Yue Cheng, Arthur Kwok Leung Cheung, Josephine Mun Yee Ko, Yee Peng Phoon, Maria L. Lung
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 420.
https://doi.org/10.1158/1538-7445.AM2012-420
Published: 15 April 2012
View article titled, Abstract 420: Physiological β-catenin signaling regulates pluripotency genes in cancer microcell hybrids
Journal Articles

Extracellular Protease ADAMTS9 Suppresses Esophageal and Nasopharyngeal Carcinoma Tumor Formation by Inhibiting Angiogenesis

Paulisally Hau Yi Lo, Hong Lok Lung, Arthur Kwok Leung Cheung, Suneel S. Apte, Kwok Wah Chan, Fung Mei Kwong, Josephine Mun Yee Ko, Yue Cheng, Simon Law, Gopesh Srivastava, Eugene R. Zabarovsky, Sai Wah Tsao, Johnny Cheuk On Tang, Eric J. Stanbridge, Maria Li Lung
Journal: Cancer Research
Cancer Res (2010) 70 (13): 5567–5576.
https://doi.org/10.1158/0008-5472.CAN-09-4510
Published: 30 June 2010
View article titled, Extracellular Protease <em>ADAMTS9</em> Suppresses Esophageal and Nasopharyngeal Carcinoma Tumor Formation by Inhibiting Angiogenesis
Open the PDF for Extracellular Protease <em>ADAMTS9</em> Suppresses Esophageal and Nasopharyngeal Carcinoma Tumor Formation by Inhibiting Angiogenesis in another window
Includes: Supplementary data
Journal Articles

Abstract 3061: Tumor suppressive and angiogenic role of THSD1 in esophageal squamous cell carcinoma and nasopharyngeal carcinoma

Josephine Mun Yee Ko, Arthur KL Cheung, Maria Li Lung
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3061.
https://doi.org/10.1158/1538-7445.AM10-3061
Published: 15 April 2010
View article titled, Abstract 3061: Tumor suppressive and angiogenic role of <em>THSD1</em> in esophageal squamous cell carcinoma and nasopharyngeal carcinoma
Journal Articles

Abstract 3080: Functional studies of a cell cycle and angiogenesis-related candidate tumor suppressor gene, Mirror image polydactyly 1, in nasopharyngeal carcinoma

Arthur Kwok Leung Cheung, Hong Lok Lung, Josephine Mun Yee Ko, Maria Li Lung
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3080.
https://doi.org/10.1158/1538-7445.AM10-3080
Published: 15 April 2010
View article titled, Abstract 3080: Functional studies of a cell cycle and angiogenesis-related candidate tumor suppressor gene, <em>Mirror image polydactyly 1</em>, in nasopharyngeal carcinoma
Journal Articles

Functional complementation and gene expression profile analysis identified THSD1 at 13q14 as a novel candidate tumor suppressor gene for esophageal squamous cell carcinoma

Josephine Mun Yee KO, Maria Li Lung, PL Chan, WL Yau, HK Chan, KC Chan, ZY Yu, FM Kwong, FM Kwong, LD Miller, ET Liu, LC Yang, P Lo, E Stanbridge, J Tang, G Srivastava, SW Tsao, S Law
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 180.
Published: 01 May 2008
View article titled, Functional complementation and gene expression profile analysis identified <em>THSD1</em> at 13q14 as a novel candidate tumor suppressor gene for esophageal squamous cell carcinoma