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Joseph J. Cullen
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Journal Articles

Abstract 4677: Characterizing resistant and metastatic phenotypes to pharmacological ascorbate in pancreatic cancer

Amanda N. Pope, Brianne R. O'Leary, Juan Du, Garry R. Buettner, Michael D. Henry, Joseph J. Cullen
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4677.
https://doi.org/10.1158/1538-7445.AM2024-4677
Published: 22 March 2024
View article titled, Abstract 4677: Characterizing resistant and metastatic phenotypes to pharmacological ascorbate in pancreatic cancer
Journal Articles

Dual Oxidase-Induced Sustained Generation of Hydrogen Peroxide Contributes to Pharmacologic Ascorbate-Induced Cytotoxicity

Adrienne R. Gibson, Brianne R. O'Leary, Juan Du, Ehab H. Sarsour, Amanda L. Kalen, Brett A. Wagner, Jeffrey M. Stolwijk, Kelly C. Falls-Hubert, Matthew S. Alexander, Rory S. Carroll, Douglas R. Spitz, Garry R. Buettner, Prabhat C. Goswami, Joseph J. Cullen
Journal: Cancer Research
Cancer Res (2020) 80 (7): 1401–1413.
https://doi.org/10.1158/0008-5472.CAN-19-3094
Published: 02 April 2020
View article titled, Dual Oxidase-Induced Sustained Generation of Hydrogen Peroxide Contributes to Pharmacologic Ascorbate-Induced Cytotoxicity
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Includes: Supplementary data
Journal Articles

Pharmacologic Ascorbate Reduces Radiation-Induced Normal Tissue Toxicity and Enhances Tumor Radiosensitization in Pancreatic Cancer

Matthew S. Alexander, Justin G. Wilkes, Samuel R. Schroeder, Garry R. Buettner, Brett A. Wagner, Juan Du, Katherine Gibson-Corley, Brianne R. O’Leary, Douglas R. Spitz, John M. Buatti, Daniel J. Berg, Kellie L. Bodeker, Sandy Vollstedt, Heather A. Brown, Bryan G. Allen, Joseph J. Cullen
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (24): 6838–6851.
https://doi.org/10.1158/0008-5472.CAN-18-1680
Published: 13 December 2018
View article titled, Pharmacologic Ascorbate Reduces Radiation-Induced Normal Tissue Toxicity and Enhances Tumor Radiosensitization in Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer

Juan Du, John A. Cieslak, III, Jessemae L. Welsh, Zita A. Sibenaller, Bryan G. Allen, Brett A. Wagner, Amanda L. Kalen, Claire M. Doskey, Robert K. Strother, Anna M. Button, Sarah L. Mott, Brian Smith, Susan Tsai, James Mezhir, Prabhat C. Goswami, Douglas R. Spitz, Garry R. Buettner, Joseph J. Cullen
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (16): 3314–3326.
https://doi.org/10.1158/0008-5472.CAN-14-1707
Published: 13 August 2015
View article titled, Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

Manganoporphyrins Increase Ascorbate-Induced Cytotoxicity by Enhancing H2O2 Generation

Malvika Rawal, Samuel R. Schroeder, Brett A. Wagner, Cameron M. Cushing, Jessemae L. Welsh, Anna M. Button, Juan Du, Zita A. Sibenaller, Garry R. Buettner, Joseph J. Cullen
Journal: Cancer Research
Series: Author Choice
Cancer Res (2013) 73 (16): 5232–5241.
https://doi.org/10.1158/0008-5472.CAN-13-0470
Published: 13 August 2013
View article titled, Manganoporphyrins Increase Ascorbate-Induced Cytotoxicity by Enhancing H<sub>2</sub>O<sub>2</sub> Generation
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Includes: Supplementary data
Journal Articles

Enhancing the Antitumor Activity of Adriamycin and Ionizing Radiation

Wenqing Sun, Amanda L. Kalen, Brian J. Smith, Joseph J. Cullen, Larry W. Oberley
Journal: Cancer Research
Cancer Res (2009) 69 (10): 4294–4300.
https://doi.org/10.1158/0008-5472.CAN-09-0396
Published: 15 May 2009
View article titled, Enhancing the Antitumor Activity of Adriamycin and Ionizing Radiation
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Journal Articles

Extracellular Redox State Regulates Features Associated with Prostate Cancer Cell Invasion

Luksana Chaiswing, Weixiong Zhong, Joseph J. Cullen, Larry W. Oberley, Terry D. Oberley
Journal: Cancer Research
Cancer Res (2008) 68 (14): 5820–5826.
https://doi.org/10.1158/0008-5472.CAN-08-0162
Published: 15 July 2008
View article titled, Extracellular Redox State Regulates Features Associated with Prostate Cancer Cell Invasion
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Includes: Supplementary data
Journal Articles

Dicumarol induces oxidative stress, cytotoxicity, and mitochondrial superoxide generation in pancreatic cancer cells

David H. Daniels, Anne M. Lewis, Larry W. Oberley, Joseph J. Cullen
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 725.
Published: 01 May 2005
View article titled, Dicumarol induces oxidative stress, cytotoxicity, and mitochondrial superoxide generation in pancreatic cancer cells
Journal Articles

Dicumarol Inhibition of NADPH:Quinone Oxidoreductase Induces Growth Inhibition of Pancreatic Cancer via a Superoxide-mediated Mechanism

Joseph J. Cullen, Marilyn M. Hinkhouse, Matthew Grady, Andrew W. Gaut, Jingru Liu, Yu Ping Zhang, Christine J. Darby Weydert, Frederick E. Domann, Larry W. Oberley
Journal: Cancer Research
Cancer Res (2003) 63 (17): 5513–5520.
Published: 18 September 2003
View article titled, Dicumarol Inhibition of NADPH:Quinone Oxidoreductase Induces Growth Inhibition of Pancreatic Cancer via a Superoxide-mediated Mechanism
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Journal Articles

The Role of Manganese Superoxide Dismutase in the Growth of Pancreatic Adenocarcinoma

Joseph J. Cullen, Christine Weydert, Marilyn M. Hinkhouse, Justine Ritchie, Frederick E. Domann, Douglas Spitz, Larry W. Oberley
Journal: Cancer Research
Cancer Res (2003) 63 (6): 1297–1303.
Published: 15 March 2003
View article titled, The Role of Manganese Superoxide Dismutase in the Growth of Pancreatic Adenocarcinoma
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