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Joseph Geradts
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Journal Articles

Abstract P4-06-09: Prediction of oncotype DX recurrence score by patho-biologic variables and three surrogate models

Joseph Geradts, Aisha Kousar, Jan Wong, Nasreen Vohra, Mahvish Muzaffar, Anas Mohamed
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P4-06-09.
https://doi.org/10.1158/1538-7445.SABCS21-P4-06-09
Published: 15 February 2022
View articletitled, Abstract P4-06-09: Prediction of oncotype DX recurrence score by patho-biologic variables and three surrogate models
Journal Articles

Abstract PO-068: Intratumoral heterogeneity of prognostic multigene signatures for breast cancer

Amber N. Hurson, Alina Hamilton, Linnea T. Olsson, Erin L. Kirk, Benjamin C. Calhoun, Joseph Geradts, Mark E. Sherman, Melissa A. Troester
Journal: Cancer Research
Cancer Res (2020) 80 (21_Supplement): PO-068.
https://doi.org/10.1158/1538-7445.TUMHET2020-PO-068
Published: 03 November 2020
View articletitled, Abstract PO-068: Intratumoral heterogeneity of prognostic multigene signatures for breast cancer
Journal Articles

XIAP Regulation by MNK Links MAPK and NFκB Signaling to Determine an Aggressive Breast Cancer Phenotype

Myron K. Evans, Michael C. Brown, Joseph Geradts, Xuhui Bao, Timothy J. Robinson, Mohit Kumar Jolly, Peter B. Vermeulen, Gregory M. Palmer, Matthias Gromeier, Herbert Levine, Michael A. Morse, Steven J. Van Laere, Gayathri R. Devi
Journal: Cancer Research
Cancer Res (2018) 78 (7): 1726–1738.
https://doi.org/10.1158/0008-5472.CAN-17-1667
Published: 01 April 2018
View articletitled, XIAP Regulation by MNK Links MAPK and NFκB Signaling to Determine an Aggressive Breast Cancer Phenotype
Open the PDF for XIAP Regulation by MNK Links MAPK and NFκB Signaling to Determine an Aggressive Breast Cancer Phenotype in another window
Includes: Supplementary data
Journal Articles

Abstract 2796: Development of a RAD51-based assay for determining homologous recombination proficiency and PARP inhibitor sensitivity

Bose S. Kochupurakkal, Kalindi Parmar, Jean-Bernard Lazaro, Christine Unitt, Qing Zeng, Hunter Reavis, Chirag Ganesa, Shan Zhou, Joyce Liu, Sangeetha Palakurthi, Kyle Strickland, Brooke Howitt, Panagiotis Konstantinopoulos, Paul Kirschmeier, Joseph Geradts, Ronny Drapkin, Ursula Matulonis, Alan D'Andrea, Geoffrey Shapiro
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2796.
https://doi.org/10.1158/1538-7445.AM2017-2796
Published: 01 July 2017
View articletitled, Abstract 2796: Development of a RAD51-based assay for determining homologous recombination proficiency and PARP inhibitor sensitivity
Journal Articles

Abstract CT047: Phase 1 dose-escalation study of the CDK inhibitor dinaciclib in combination with the PARP inhibitor veliparib in patients with advanced solid tumors

Geoffrey I. Shapiro, Khanh T. Do, Sara M. Tolaney, John F. Hilton, James M. Cleary, Andrew Wolanski, Brian Beardslee, Faith Hassinger, Ketki Bhushan, Dongpo Cai, Elizabeth Downey, Solida Pruitt-Thompson, Suzanne M. Barry, Bose Kochupurakkal, Joseph Geradts, Christine Unitt, Alan D. D'Andrea, Alona Muzikansky, Richard Piekarz, L. Austin Doyle, Jeffrey Supko
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): CT047.
https://doi.org/10.1158/1538-7445.AM2017-CT047
Published: 01 July 2017
View articletitled, Abstract CT047: Phase 1 dose-escalation study of the CDK inhibitor dinaciclib in combination with the PARP inhibitor veliparib in patients with advanced solid tumors
Journal Articles

CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer

Mahmoud A. Alfaqih, Erik R. Nelson, Wen Liu, Rachid Safi, Jeffery S. Jasper, Everardo Macias, Joseph Geradts, J. Will Thompson, Laura G. Dubois, Michael R. Freeman, Ching-yi Chang, Jen-Tsan Chi, Donald P. McDonnell, Stephen J. Freedland
Journal: Cancer Research
Cancer Res (2017) 77 (7): 1662–1673.
https://doi.org/10.1158/0008-5472.CAN-16-2738
Published: 02 April 2017
View articletitled, CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer
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Includes: Supplementary data
Journal Articles

Abstract LB-015: XIAP induction by the MAPK-eIF4G1 pathway drives NFκB activation in inflammatory breast cancer growth and therapeutic resistance

Myron K. Evans, Joseph Geradts, Courtney Edwards, Arianna Price, Arjun J. Arora, Amy J. Aldrich, Adrian Ramirez, Timothy J. Robinson, Peter B. Vermeulen, Steven van Laere, Gayathri R. Devi
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-015.
https://doi.org/10.1158/1538-7445.AM2016-LB-015
Published: 15 July 2016
View articletitled, Abstract LB-015: XIAP induction by the MAPK-eIF4G1 pathway drives NFκB activation in inflammatory breast cancer growth and therapeutic resistance
Journal Articles

Abstract P6-14-05: A novel link between anti-apoptotic signaling, NFκB, and SMAD7 in IBC pathobiology

Myron K Evans, Scott J Sauer, Amy J Aldrich, Joseph Geradts, Peter Vermeulen, Luc Dirix, Steven Van Laere, Gayathri R Devi
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P6-14-05.
https://doi.org/10.1158/1538-7445.SABCS14-P6-14-05
Published: 01 May 2015
View articletitled, Abstract P6-14-05: A novel link between anti-apoptotic signaling, NFκB, and SMAD7 in IBC pathobiology
Journal Articles

Abstract #2881: Prostate derived Ets factor (PDEF), an emerging biomarker in cancer

Ashwani Sood, Jianmin Wang, Bagirathan Janarthanan, Ping Liang, Hyung Kim, Joseph Geradts
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2881.
Published: 01 May 2009
View articletitled, Abstract #2881: Prostate derived Ets factor (PDEF), an emerging biomarker in cancer
Journal Articles

Quantitative Optical Spectroscopy: A Robust Tool for Direct Measurement of Breast Cancer Vascular Oxygenation and Total Hemoglobin Content In vivo

J. Quincy Brown, Lee G. Wilke, Joseph Geradts, Stephanie A. Kennedy, Gregory M. Palmer, Nirmala Ramanujam
Journal: Cancer Research
Cancer Res (2009) 69 (7): 2919–2926.
https://doi.org/10.1158/0008-5472.CAN-08-3370
Published: 01 April 2009
View articletitled, Quantitative Optical Spectroscopy: A Robust Tool for Direct Measurement of Breast Cancer Vascular Oxygenation and Total Hemoglobin Content In vivo
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Journal Articles

Use of frozen breast tissues for molecular studies: The importance of pathologic verification

Joseph Geradts, Rex Bentley, Blake Hutchinson, John Olson, Raj Dash
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5492.
Published: 01 May 2008
View articletitled, Use of frozen breast tissues for molecular studies: The importance of pathologic verification
Journal Articles

DNA copy number changes associated with progression from in situ to invasive ductal carcinoma of the breast

Mohamed Desouki, Daniel Gaile, Lori Shepherd, Devin McQuaid, Norma Nowak, Jeffrey Conroy, Shaoxi Liao, Joseph Geradts
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1675.
Published: 01 May 2008
View articletitled, DNA copy number changes associated with progression from in situ to invasive ductal carcinoma of the breast
Journal Articles

Intraoperative assessment of breast physiology via in vivo optical biopsy: potential for cancer diagnostics

J. Quincy Brown, Lee Wilke, Joseph Geradts, Lauren Tochacek, Gregory Palmer, Nirmala Ramanujam
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 5517.
Published: 01 May 2007
View articletitled, Intraoperative assessment of breast physiology via in vivo optical biopsy: potential for cancer diagnostics
Journal Articles

The tetraspanin superfamily member NET-6 is a new breast cancer suppressor gene

Joseph Geradts, Khalid Sossey-Alaoui, Sarah Hejaily, Huayi Huang
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 607.
Published: 15 April 2006
View articletitled, The tetraspanin superfamily member NET-6 is a new breast cancer suppressor gene
Journal Articles

Frequent overexpression of prostate derived ets factor (PDEF) protein in breast cancer progression

Joseph Geradts, Rakhee Saxena, Jeff Groth, Mohamed Desouki, Chalong Cheewakriangkrai, Kerry Rodabaugh, Ashwani Sood
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 780.
Published: 15 April 2006
View articletitled, Frequent overexpression of prostate derived ets factor (PDEF) protein in breast cancer progression
Journal Articles

Identification of DNA copy number abnormalities associated with the metastatic phenotype of human breast cancer using a high resolution whole genome approach

Mohamed Desouki, Daniel Gaile, Huayi Huang, Jeff Groth, Devin McQuaid, Norma Nowak, Jeff Conroy, Joseph Geradts
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 614.
Published: 15 April 2006
View articletitled, Identification of DNA copy number abnormalities associated with the metastatic phenotype of human breast cancer using a high resolution whole genome approach
Journal Articles

Genetic changes in premenopausal breast cancers from Western New York and Belarus: An array CGH study

Geetha Varma, Ram Varma, Alena Pryshchepava, Huayi Huang, Jeffrey Groth, Norma Nowak, Devin McQuaid, Jeffrey Conroy, Martin Mahoney, Kirsten Moysich, Karen Falkner, Joseph Geradts
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 652–653.
Published: 01 April 2004
View articletitled, Genetic changes in premenopausal breast cancers from Western New York and Belarus: An array CGH study
Journal Articles

The candidate tumor suppressor gene hSRBC is frequently methylated in breast cancers

Sabine Zochbauer-Muller, Martin Filipits, Barbara Ziegler, Anh Huyn, Eva-Maria Markis, Thomas Payrits, Dieter Depisch, Wolfgang Stiglbauer, Robert Pirker, Christoph C. Zielinski, Jeff Groth, Adi F. Gazdar, John D. Minna, Joseph Geradts
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 968.
Published: 01 April 2004
View articletitled, The candidate tumor suppressor gene hSRBC is frequently methylated in breast cancers
Journal Articles

Prevalence and Spectrum of p53 Mutations Associated with Smoking in Breast Cancer

Kathleen Conway, Sharon N. Edmiston, Lisa Cui, S. Scott Drouin, Jingzhong Pang, Mei He, Chiu-Kit Tse, Joseph Geradts, Lynn Dressler, Edison T. Liu, Robert Millikan, Beth Newman
Journal: Cancer Research
Cancer Res (2002) 62 (7): 1987–1995.
Published: 01 April 2002
View articletitled, Prevalence and Spectrum of p53 Mutations Associated with Smoking in Breast Cancer
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Journal Articles

5′ CpG Island Methylation of the FHIT Gene Is Correlated with Loss of Gene Expression in Lung and Breast Cancer

Sabine Zöchbauer-Müller, Kwun M. Fong, Anirban Maitra, Stephen Lam, Joseph Geradts, Raheela Ashfaq, Arvind K. Virmani, Sarah Milchgrub, Adi F. Gazdar, John D. Minna
Journal: Cancer Research
Cancer Res (2001) 61 (9): 3581–3585.
Published: 01 May 2001
View articletitled, 5′ CpG Island Methylation of the FHIT Gene Is Correlated with Loss of Gene Expression in Lung and Breast Cancer
Open the PDF for 5′ CpG Island Methylation of the FHIT Gene Is Correlated with Loss of Gene Expression in Lung and Breast Cancer in another window