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Joseph Ciccolini
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Journal Articles

Abstract 7173: Animal pharmacokinetics of an anti-Her2+ immunoliposome of docetaxel

Mathilde Dacos, Erwan Diroff, Sarah Giacometti, Joseph Ciccolini, Raphaelle Fanciullino
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7173.
https://doi.org/10.1158/1538-7445.AM2024-7173
Published: 22 March 2024
View articletitled, Abstract 7173: Animal pharmacokinetics of an anti-Her2+ immunoliposome of docetaxel
Journal Articles

Abstract 4037: Optimizing the efficacy of anti-VEGF/cytotoxics/anti-PD-1 scheduling in a lung cancer mice model through B and T cells monitoring

Guillaume Sicard, Dorian Protzenko, Sarah Giacometti, Raphaelle Fanciullino, Fabrice Barlesi, Joseph Ciccolini
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4037.
https://doi.org/10.1158/1538-7445.AM2024-4037
Published: 22 March 2024
View articletitled, Abstract 4037: Optimizing the efficacy of anti-VEGF/cytotoxics/anti-PD-1 scheduling in a lung cancer mice model through B and T cells monitoring
Journal Articles

Abstract 7162: Killing a fly with a sledgehammer: standard flat-dosing administration of Atezolizumab leads to marked overexposure in real-world lung cancer patients

Sophie Marolleau, Alice Mogenet, Mourad Hamimed, Clara Boeri, Laurent Greillier, Joseph Ciccolini
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7162.
https://doi.org/10.1158/1538-7445.AM2024-7162
Published: 22 March 2024
View articletitled, Abstract 7162: Killing a fly with a sledgehammer: standard flat-dosing administration of Atezolizumab leads to marked overexposure in real-world lung cancer patients
Journal Articles

Abstract 1857: Nanoliposomes harness tumor immunity in breast cancer models

Mathilde Dacos, Guillaume Sicard, Benoit Immordino, Sarah Giacometti, Joseph Ciccolini, Anne Rodallec, Raphaelle Fanciullino
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1857.
https://doi.org/10.1158/1538-7445.AM2023-1857
Published: 04 April 2023
View articletitled, Abstract 1857: Nanoliposomes harness tumor immunity in breast cancer models
Journal Articles

Abstract 1856: Pemetrexed-cisplatin-bevacizumab combo in lung cancer models: impact on tumor immunity

Guillaume Sicard, Sarah Giacometti, Fabrice Barlesi, Raphaelle Fanciullino, Joseph Ciccolini
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1856.
https://doi.org/10.1158/1538-7445.AM2023-1856
Published: 04 April 2023
View articletitled, Abstract 1856: Pemetrexed-cisplatin-bevacizumab combo in lung cancer models: impact on tumor immunity
Journal Articles

Abstract 1144: A multiplex LC-MS/MS method for assaying mAbs in oncology: Application to the CETUXIMAX GPCO-Unicancer trial on cetuximab pharmacokinetics in head and neck cancer patients

Clemence Marin, Nihel Khoudour, Aurélien Millet, Dorothée Lebert, Pauline Bros, Fabienne Thomas, David Ternant, Jerôme Guitton, Mourad Hamimed, Benoit Blanchet, Sebastien Salas, Joseph Ciccolini
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1144.
https://doi.org/10.1158/1538-7445.AM2022-1144
Published: 15 June 2022
View articletitled, Abstract 1144: A multiplex LC-MS/MS method for assaying mAbs in oncology: Application to the CETUXIMAX GPCO-Unicancer trial on cetuximab pharmacokinetics in head and neck cancer patients
Journal Articles

Abstract LB120: Comprehensive biomarkers analysis to explain resistances to PD1-L1 ICIs: The precision immuno-oncology for advanced non-small cell lung cancer (PIONeeR) trial

Laurent Greillier, Florence Monville, Vanina Leca, Frédéric Vely, Stephane Garcia, Joseph Ciccolini, Florence Sabatier, Gilbert Ferrani, Nawel Boudai, Lamia Ghezali, Marcellin Landri, Clémence Marin, Mourad Hamimed, Laurent Arnaud, Melanie Karlsen, Kevin Atsou, Sivan Bokobza, Pauline Fleury, Arnaud Boyer, Clarisse Audigier-Valette, Stéphanie Martinez, Hervé Pegliasco, Patrice Ray, Lionel Falchero, Antoine Serre, Nicolas Cloarec, Louisiane Lebas, Stephane Hominal, Patricia Barre, Sarah Zahi, Ahmed Frikha, Pierre Bory, Maryannick Le Ray, Lilian Laborde, Virginie Martin, Richard Malkoun, Marie Roumieux, Julien Mazieres, Maurice Perol, Eric Vivier, Sebastien Benzekry, Jacques Fieschi, Fabrice Barlesi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): LB120.
https://doi.org/10.1158/1538-7445.AM2022-LB120
Published: 15 June 2022
View articletitled, Abstract LB120: Comprehensive biomarkers analysis to explain resistances to PD1-L1 ICIs: The precision immuno-oncology for advanced non-small cell lung cancer (PIONeeR) trial
Journal Articles

Abstract 2022: Model-informed pediatric drug development: oral vinorelbine in low-grade glioma as a case study

Mourad HAMIMED, Pierre LEBLOND, Aurélie DUMONT, Florence GATTACCECA, Emmanuelle TRESCH-BRUNEEL, Alicia PROBST, Pascal CHASTAGNER, Anne PAGNIER, Emilie DE CARLI, Natacha ENTZ-WERLÉ, Jacques GRILL, Isabelle AERTS, Didier FRAPPAZ, Anne-Isabelle BERTOZZI-SALAMON, Caroline SOLAS, Nicolas ANDRÉ, Joseph Ciccolini
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2022.
https://doi.org/10.1158/1538-7445.AM2022-2022
Published: 15 June 2022
View articletitled, Abstract 2022: Model-informed pediatric drug development: oral vinorelbine in low-grade glioma as a case study
Journal Articles

Abstract 1150: Pharmacokinetics and pharmacogenetics of liposomal cytarabine in AML patients treated with CPX-351

Melanie Donnette, Mourad Hamimed, Joseph Ciccolini, Regis Costello, Laure Delassus, Geoffroy Venton, Raphaelle Fanciullino
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1150.
https://doi.org/10.1158/1538-7445.AM2022-1150
Published: 15 June 2022
View articletitled, Abstract 1150: Pharmacokinetics and pharmacogenetics of liposomal cytarabine in AML patients treated with CPX-351
Journal Articles

Abstract 1145: Therapeutic drug monitoring of Sunitinib in real-world patients

Laurent Ferrer, Jonathan Chauvin, Dr Jean-Laurent Deville, Joseph Ciccolini
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1145.
https://doi.org/10.1158/1538-7445.AM2022-1145
Published: 15 June 2022
View articletitled, Abstract 1145: Therapeutic drug monitoring of Sunitinib in real-world patients
Journal Articles

Abstract 5493: Mathematical modeling of antibody nanoconjugates transport quantifies the impact of the tumor microenvironment on drug penetration

Cristina Vaghi, Anne Rodallec, Guillaume Sicard, Florian Correard, Raphaelle Fanciullino, Joseph Ciccolini, Clair Poignard, Sebastien Benzekry
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5493.
https://doi.org/10.1158/1538-7445.AM2020-5493
Published: 15 August 2020
View articletitled, Abstract 5493: Mathematical modeling of antibody nanoconjugates transport quantifies the impact of the tumor microenvironment on drug penetration
Journal Articles

Abstract 6244: Turning poorly vascularized tumors into highly vascularized tumors with nanoparticles: Proof of concept and pharmacometric analysis

Guillaume Sicard, Anne Rodallec, Florian Correard, Cristina Vaghi, Clair Poignard, Joseph Ciccolini, Sébastien Benzekry, Arnauld Sergé, Raphaelle Fanciullino
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6244.
https://doi.org/10.1158/1538-7445.AM2020-6244
Published: 15 August 2020
View articletitled, Abstract 6244: Turning poorly vascularized tumors into highly vascularized tumors with nanoparticles: Proof of concept and pharmacometric analysis
Journal Articles

Abstract 3000: Impact of trastuzumab coating when prototyping immunoliposomes in breast cancer models: The more the merrier

Anne Rodallec, Corentin Franco, Stéphane Robert, Guillaume Sicard, Sarah Giacometti, Ariel Savina, Fanny Bouquet, Bruno Lacarelle, Joseph Ciccolini, Philippe Poncelet, Raphaelle Fanciullino
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3000.
https://doi.org/10.1158/1538-7445.AM2019-3000
Published: 01 July 2019
View articletitled, Abstract 3000: Impact of trastuzumab coating when prototyping immunoliposomes in breast cancer models: The more the merrier
Journal Articles

Abstract 3898: CDA predicts life-threatening toxicities in AML patients treated with cytarabine

Raphaelle Fanciullino, Laure Farnault, Mélanie Donnette, Vadim Ivanov, Geoffroy Venton, Joseph Ciccolini, Yael Berda-Haddad, Catherine Roche, L'Houcine Ouafik, Bruno Lacarelle, Regis Costello
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3898.
https://doi.org/10.1158/1538-7445.AM2018-3898
Published: 01 July 2018
View articletitled, Abstract 3898: CDA predicts life-threatening toxicities in AML patients treated with cytarabine
Journal Articles

Abstract 3892: Upfront DPD screening with adaptive dosing to secure 5-FU administration in head and neck cancer patients

Joseph Ciccolini, Manon Launay, Charlotte Dupuis, Florence Duffaud, Bruno Lacarelle, Sébastien Salas
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3892.
https://doi.org/10.1158/1538-7445.AM2018-3892
Published: 01 July 2018
View articletitled, Abstract 3892: Upfront DPD screening with adaptive dosing to secure 5-FU administration in head and neck cancer patients
Journal Articles

Abstract 3709: Characterization, in vitro and in vivo efficacy studies of docetaxel trastuzumab stealth immunoliposome in human breast cancer models

Anne Rodallec, Jean Michel Brunel, Stephane Robert, Sarah Giacometti, Ariel Savina, Fanny Bouquet, Bruno Lacarelle, Joseph Ciccolini, Raphaelle Fanciullino
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3709.
https://doi.org/10.1158/1538-7445.AM2018-3709
Published: 01 July 2018
View articletitled, Abstract 3709: Characterization, in vitro and in vivo efficacy studies of docetaxel trastuzumab stealth immunoliposome in human breast cancer models
Journal Articles

Pharmacokinetics and Pharmacodynamics-Based Mathematical Modeling Identifies an Optimal Protocol for Metronomic Chemotherapy

Joseph Ciccolini, Dominique Barbolosi, Christophe Meille, Aurélie Lombard, Cindy Serdjebi, Sarah Giacometti, Laetitia Padovani, Eddy Pasquier, Nicolas André
Journal: Cancer Research
Cancer Res (2017) 77 (17): 4723–4733.
https://doi.org/10.1158/0008-5472.CAN-16-3130
Published: 31 August 2017
View articletitled, Pharmacokinetics and Pharmacodynamics-Based Mathematical Modeling Identifies an Optimal Protocol for Metronomic Chemotherapy
Open the PDF for Pharmacokinetics and Pharmacodynamics-Based Mathematical Modeling Identifies an Optimal Protocol for Metronomic Chemotherapy in another window
Includes: Supplementary data
Journal Articles

Abstract 4529: Optimization of the sequence for the administration of bevacizumab in combination with pemetrexed and cisplatin in NSCLC : a pharmacology based in vivo study

arnaud boyer, diane-charlotte imbs, raouf el cheikh, celine mascaux, fabrice barlesi, dominique barbolosi, sebastien benzekry, joseph ciccolini
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4529.
https://doi.org/10.1158/1538-7445.AM2017-4529
Published: 01 July 2017
View articletitled, Abstract 4529: Optimization of the sequence for the administration of bevacizumab in combination with pemetrexed and cisplatin in NSCLC : a pharmacology based in vivo study
Journal Articles

Abstract 5048: Residual concentrations of cetuximab predict clinical response in head and neck cancer patients

Joseph Ciccolini, François Becher, Diane-Charlotte Imbs, Claire Fournel, Florence Duffaud, Bruno Lacarelle, Sebastien Salas
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5048.
https://doi.org/10.1158/1538-7445.AM2017-5048
Published: 01 July 2017
View articletitled, Abstract 5048: Residual concentrations of cetuximab predict clinical response in head and neck cancer patients
Journal Articles

Abstract 4062: A computational driven protocol of metronomic oral vinorelbine in metastatic non small cell lung cancer

Diane-Charlotte Imbs, Raouf El Cheikh, Joseph Ciccolini, Raphaël Serre, Fabrice Barlesi, Dominique Barbolosi
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4062.
https://doi.org/10.1158/1538-7445.AM2017-4062
Published: 01 July 2017
View articletitled, Abstract 4062: A computational driven protocol of metronomic oral vinorelbine in metastatic non small cell lung cancer