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Jose R. Conejo-Garcia
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Journal Articles

Abstract 6346: IgG engineered to target PIGR-mediated transcytosis specifically targets intracellular oncoproteins and abrogated tumor growth

Carmen Maria Anadon Galindo, Luis U. Lopez-Bailon, Ricardo A. Chaurio, Jessica A. Mine, Noah E. Plappert, Jose R. Conejo-Garcia
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6346.
https://doi.org/10.1158/1538-7445.AM2024-6346
Published: 22 March 2024
View article titled, Abstract 6346: IgG engineered to target PIGR-mediated transcytosis specifically targets intracellular oncoproteins and abrogated tumor growth
Journal Articles

Abstract 71: Differential infiltration of key immune cell populations across malignancies varying by immunogenic potential and likelihood of response to immunotherapy

Ahmad A. Tarhini, Islam Eljilany, Sam Coleman, Dale J. Hedges, Martin McCarter, John Carpten, Howard Colman, Abdul Rafeh Naqash, Igor Puzanov, Susanne Arnold, Michelle Churchman, Patrick Hwu, William S. Dalton, George J. Weiner, Aik Choon Tan, Jose R. Conejo-Garcia, Paulo C. Rodriguez
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 71.
https://doi.org/10.1158/1538-7445.AM2024-71
Published: 22 March 2024
View article titled, Abstract 71: Differential infiltration of key immune cell populations across malignancies varying by immunogenic potential and likelihood of response to immunotherapy
Journal Articles

Abstract A089: Influence of pre-diagnosis aspirin use on epithelial ovarian cancer tumor immune microenvironment markers: results from the Nurses’ Health Study (NHS) and NHSII

Nicola S. Meagher, Cassandra Hathaway, Mary K. Townsend, Mollie E. Barnard, Jose R. Conejo-Garcia, Brooke L. Fridley, Daryoush Saeed-Vafa, Britton Trabert, Shelley S. Tworoger, Melissa A. Merritt
Journal: Cancer Research
Cancer Res (2024) 84 (5_Supplement_2): A089.
https://doi.org/10.1158/1538-7445.OVARIAN23-A089
Published: 04 March 2024
View article titled, Abstract A089: Influence of pre-diagnosis aspirin use on epithelial ovarian cancer tumor immune microenvironment markers: results from the Nurses’ Health Study (NHS) and NHSII
Journal Articles

Abstract 3008: Association between distress and the tumor immune microenvironment in women with ovarian cancer

Cassandra A. Hathaway, Mary K. Townsend, Jose R. Conejo-Garcia, Brooke L. Fridley, Carlos Moran Segura, Jonathan V. Nguyen, Naoko Sasamoto, Daryoush Saeed-Vafa, Kathryn L. Terry, Laura D. Kubzansky, Shelley S. Tworoger
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3008.
https://doi.org/10.1158/1538-7445.AM2023-3008
Published: 04 April 2023
View article titled, Abstract 3008: Association between distress and the tumor immune microenvironment in women with ovarian cancer
Journal Articles

Tumor Intrinsic PD-L1 Promotes DNA Repair in Distinct Cancers and Suppresses PARP Inhibitor–Induced Synthetic Lethality

Anand V.R. Kornepati, Jacob T. Boyd, Clare E. Murray, Julia Saifetiarova, Bárbara de la Peña Avalos, Cody M. Rogers, Haiyan Bai, Alvaro S. Padron, Yiji Liao, Carlos Ontiveros, Robert S. Svatek, Robert Hromas, Rong Li, Yanfen Hu, Jose R. Conejo-Garcia, Ratna K. Vadlamudi, Weixing Zhao, Eloïse Dray, Patrick Sung, Tyler J. Curiel
Journal: Cancer Research
Cancer Res (2022) 82 (11): 2156–2170.
https://doi.org/10.1158/0008-5472.CAN-21-2076
Published: 06 June 2022
View article titled, Tumor Intrinsic PD-L1 Promotes DNA Repair in Distinct Cancers and Suppresses PARP Inhibitor–Induced Synthetic Lethality
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Journal Articles

Tumor Expression Quantitative Trait Methylation Screening Reveals Distinct CpG Panels for Deconvolving Cancer Immune Signatures

Xiaoqing Yu, Ling Cen, Y. Ann Chen, Joseph Markowitz, Timothy I. Shaw, Kenneth Y. Tsai, Jose R. Conejo-Garcia, Xuefeng Wang
Journal: Cancer Research
Cancer Res (2022) 82 (9): 1724–1735.
https://doi.org/10.1158/0008-5472.CAN-21-3113
Published: 03 May 2022
View article titled, Tumor Expression Quantitative Trait Methylation Screening Reveals Distinct CpG Panels for Deconvolving Cancer Immune Signatures
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Includes: Supplementary data
Journal Articles

IgA-Dominated Humoral Immune Responses Govern Patients' Outcome in Endometrial Cancer

Gunjan Mandal, Subir Biswas, Carmen M. Anadon, Xiaoqing Yu, Chandler D. Gatenbee, Sandhya Prabhakaran, Kyle K. Payne, Ricardo A. Chaurio, Alexandra Martin, Patrick Innamarato, Carlos Moran, John J. Powers, Carly M. Harro, Jessica A. Mine, Kimberly B. Sprenger, Kristen E. Rigolizzo, Xuefeng Wang, Tyler J. Curiel, Paulo C. Rodriguez, Alexander R. Anderson, Ozlen Saglam, Jose R. Conejo-Garcia
Journal: Cancer Research
Cancer Res (2022) 82 (5): 859–871.
https://doi.org/10.1158/0008-5472.CAN-21-2376
Published: 03 March 2022
View article titled, IgA-Dominated Humoral Immune Responses Govern Patients' Outcome in Endometrial Cancer
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Includes: Supplementary data
Journal Articles

Abstract 1635: Sirt2 blockade promotes T cell metabolism and restores the anti-tumor immunity

Imene Hamaidi, Lin Zhang, Nayoung Kim, Min Hsuan Wang, Cristina Iclozan, Bin Fang, Min Liu, John M. Koomen, Anders E. Berglund, Sean J. Yoder, Jiqiang Yao, Robert W. Engelman, Ben C. Creelan, Jose R. Conejo-Garcia, James J. Mulé, Scott J. Antonia, Sungjune Kim
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1635.
https://doi.org/10.1158/1538-7445.AM2021-1635
Published: 01 July 2021
View article titled, Abstract 1635: Sirt2 blockade promotes T cell metabolism and restores the anti-tumor immunity
Journal Articles

CD122-Selective IL2 Complexes Reduce Immunosuppression, Promote Treg Fragility, and Sensitize Tumor Response to PD-L1 Blockade

Justin M. Drerup, Yilun Deng, Sri Lakshmi Pandeswara, Álvaro S. Padrón, Ryan M. Reyes, Xinyue Zhang, Jenny Mendez, Aijie Liu, Curtis A. Clark, Wanjiao Chen, José R. Conejo-Garcia, Vincent Hurez, Harshita Gupta, Tyler J. Curiel
Journal: Cancer Research
Cancer Res (2020) 80 (22): 5063–5075.
https://doi.org/10.1158/0008-5472.CAN-20-0002
Published: 13 November 2020
View article titled, CD122-Selective IL2 Complexes Reduce Immunosuppression, Promote Treg Fragility, and Sensitize Tumor Response to PD-L1 Blockade
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Includes: Supplementary data
Journal Articles

AMPK Alpha-1 Intrinsically Regulates the Function and Differentiation of Tumor Myeloid-Derived Suppressor Cells

Jimena Trillo-Tinoco, Rosa A. Sierra, Eslam Mohamed, Yu Cao, Álvaro de Mingo-Pulido, Danielle L. Gilvary, Carmen M. Anadon, Tara Lee Costich, Sheng Wei, Elsa R. Flores, Brian Ruffell, José R. Conejo-Garcia, Paulo C. Rodriguez
Journal: Cancer Research
Cancer Res (2019) 79 (19): 5034–5047.
https://doi.org/10.1158/0008-5472.CAN-19-0880
Published: 01 October 2019
View article titled, AMPK Alpha-1 Intrinsically Regulates the Function and Differentiation of Tumor Myeloid-Derived Suppressor Cells
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Includes: Supplementary data
Journal Articles

Abstract SY01-02: Blockade of estrogen signaling boosts antitumor immunity by dwindling cancer-promoting myelopoiesis

Nikolaos Svoronos, Alfredo Perales-Puchalt, Jose R. Conejo-Garcia
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): SY01-02.
https://doi.org/10.1158/1538-7445.AM2018-SY01-02
Published: 01 July 2018
View article titled, Abstract SY01-02: Blockade of estrogen signaling boosts antitumor immunity by dwindling cancer-promoting myelopoiesis
Journal Articles

Abstract 3145: Characterization of novel immune checkpoint receptors within the breast cancer tumor microenvironment

Austin D. Williams, Jean S. Campbell, Lauri D. Aicher, Kyle K. Payne, Jose R. Conejo-Garcia, Robert H. Pierce, Julia Tchou
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3145.
https://doi.org/10.1158/1538-7445.AM2018-3145
Published: 01 July 2018
View article titled, Abstract 3145: Characterization of novel immune checkpoint receptors within the breast cancer tumor microenvironment
Journal Articles

Trametinib Drives T-cell–Dependent Control of KRAS-Mutated Tumors by Inhibiting Pathological Myelopoiesis

Michael J. Allegrezza, Melanie R. Rutkowski, Tom L. Stephen, Nikolaos Svoronos, Alfredo Perales-Puchalt, Jenny M. Nguyen, Kyle K. Payne, Sunil Singhal, Evgeniy B. Eruslanov, Julia Tchou, Jose R. Conejo-Garcia
Journal: Cancer Research
Cancer Res (2016) 76 (21): 6253–6265.
https://doi.org/10.1158/0008-5472.CAN-16-1308
Published: 31 October 2016
View article titled, Trametinib Drives T-cell–Dependent Control of KRAS-Mutated Tumors by Inhibiting Pathological Myelopoiesis
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Journal Articles

BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer

Yuhki Yokoyama, Hengrui Zhu, Jeong Heon Lee, Andrew V. Kossenkov, Sherry Y. Wu, Jayamanna M. Wickramasinghe, Xiangfan Yin, Katherine C. Palozola, Alessandro Gardini, Louise C. Showe, Kenneth S. Zaret, Qin Liu, David Speicher, Jose R. Conejo-Garcia, James E. Bradner, Zhiguo Zhang, Anil K. Sood, Tamas Ordog, Benjamin G. Bitler, Rugang Zhang
Journal: Cancer Research
Cancer Res (2016) 76 (21): 6320–6330.
https://doi.org/10.1158/0008-5472.CAN-16-0854
Published: 31 October 2016
View article titled, BET Inhibitors Suppress ALDH Activity by Targeting <em>ALDH1A1</em> Super-Enhancer in Ovarian Cancer
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Includes: Supplementary data
Journal Articles

IL15 Agonists Overcome the Immunosuppressive Effects of MEK Inhibitors

Michael J. Allegrezza, Melanie R. Rutkowski, Tom L. Stephen, Nikolaos Svoronos, Amelia J. Tesone, Alfredo Perales-Puchalt, Jenny M. Nguyen, Fahmida Sarmin, Mee R. Sheen, Emily K. Jeng, Julia Tchou, Hing C. Wong, Steven N. Fiering, Jose R. Conejo-Garcia
Journal: Cancer Research
Cancer Res (2016) 76 (9): 2561–2572.
https://doi.org/10.1158/0008-5472.CAN-15-2808
Published: 01 May 2016
View article titled, IL15 Agonists Overcome the Immunosuppressive Effects of MEK Inhibitors
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Includes: Supplementary data
Journal Articles

Avirulent Toxoplasma gondii Generates Therapeutic Antitumor Immunity by Reversing Immunosuppression in the Ovarian Cancer Microenvironment

Jason R. Baird, Barbara A. Fox, Kiah L. Sanders, Patrick H. Lizotte, Juan R. Cubillos-Ruiz, Uciane K. Scarlett, Melanie R. Rutkowski, Jose R. Conejo-Garcia, Steven Fiering, David J. Bzik
Journal: Cancer Research
Cancer Res (2013) 73 (13): 3842–3851.
https://doi.org/10.1158/0008-5472.CAN-12-1974
Published: 30 June 2013
View article titled, Avirulent <em>Toxoplasma gondii</em> Generates Therapeutic Antitumor Immunity by Reversing Immunosuppression in the Ovarian Cancer Microenvironment
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Includes: Supplementary data
Journal Articles

Reprogramming Tumor-Associated Dendritic Cells In Vivo Using miRNA Mimetics Triggers Protective Immunity against Ovarian Cancer

Juan R. Cubillos-Ruiz, Jason R. Baird, Amelia J. Tesone, Melanie R. Rutkowski, Uciane K. Scarlett, Ana L. Camposeco-Jacobs, Jorge Anadon-Arnillas, Noah M. Harwood, Murray Korc, Steven N. Fiering, Lorenzo F. Sempere, Jose R. Conejo-Garcia
Journal: Cancer Research
Cancer Res (2012) 72 (7): 1683–1693.
https://doi.org/10.1158/0008-5472.CAN-11-3160
Published: 01 April 2012
View article titled, Reprogramming Tumor-Associated Dendritic Cells <em>In Vivo</em> Using miRNA Mimetics Triggers Protective Immunity against Ovarian Cancer
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Includes: Supplementary data
Journal Articles

Abstract LB-360: Fluorescence-based co-registration with protein markers reveals distinct cellular compartments for altered microRNA expression in solid tumors

Lorenzo F. Sempere, Meir Preis, Todd Yezefski, Haoxu Ouyang, Arief A. Suriawinata, Asli Silahtaroglu, Jose R. Conejo-Garcia, Sakari Kauppinen, Wendy Wells, Murray Korc
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-360.
https://doi.org/10.1158/1538-7445.AM10-LB-360
Published: 15 April 2010
View article titled, Abstract LB-360: Fluorescence-based co-registration with protein markers reveals distinct cellular compartments for altered microRNA expression in solid tumors
Journal Articles

In situ Stimulation of CD40 and Toll-like Receptor 3 Transforms Ovarian Cancer–Infiltrating Dendritic Cells from Immunosuppressive to Immunostimulatory Cells

Uciane K. Scarlett, Juan R. Cubillos-Ruiz, Yolanda C. Nesbeth, Diana G. Martinez, Xavier Engle, Andrew T. Gewirtz, Cory L. Ahonen, Jose R. Conejo-Garcia
Journal: Cancer Research
Cancer Res (2009) 69 (18): 7329–7337.
https://doi.org/10.1158/0008-5472.CAN-09-0835
Published: 14 September 2009
View article titled, <em>In situ</em> Stimulation of CD40 and Toll-like Receptor 3 Transforms Ovarian Cancer–Infiltrating Dendritic Cells from Immunosuppressive to Immunostimulatory Cells
Open the PDF for <em>In situ</em> Stimulation of CD40 and Toll-like Receptor 3 Transforms Ovarian Cancer–Infiltrating Dendritic Cells from Immunosuppressive to Immunostimulatory Cells in another window
Includes: Supplementary data
Journal Articles

CCL5-Mediated Endogenous Antitumor Immunity Elicited by Adoptively Transferred Lymphocytes and Dendritic Cell Depletion

Yolanda Nesbeth, Uciane Scarlett, Juan Cubillos-Ruiz, Diana Martinez, Xavier Engle, Mary-Jo Turk, Jose R. Conejo-Garcia
Journal: Cancer Research
Cancer Res (2009) 69 (15): 6331–6338.
https://doi.org/10.1158/0008-5472.CAN-08-4329
Published: 29 July 2009
View article titled, CCL5-Mediated Endogenous Antitumor Immunity Elicited by Adoptively Transferred Lymphocytes and Dendritic Cell Depletion
Open the PDF for CCL5-Mediated Endogenous Antitumor Immunity Elicited by Adoptively Transferred Lymphocytes and Dendritic Cell Depletion in another window
Includes: Supplementary data