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Journal Articles

Abstract 673: Exploration of tissue morphologies in breast cancer samples using unsupervised machine learning

Riku Turkki, Dmitrii Bychkov, Nina Linder, Jorma Isola, Heikki Joensuu, Johan Lundin

Cancer Res (2017) 77 (13_Supplement): 673.

https://doi.org/10.1158/1538-7445.AM2017-673

Published: 01 July 2017

View article titled, Abstract 673: Exploration of tissue morphologies in breast cancer samples using unsupervised machine learning

Journal Articles

Abstract P5-02-01: Comparison of ESR1, PGR, HER2 and KI67 expression by central IHC and MammaTyper® RT-qPCR kit in the FinHer trial

Ralph M Wirtz, Pirkko-Liisa Kellokumpu-Lehtinen, Jorma Isola, Vesa Kataja, Petri Bono, Taina Turpeenniemi-Hujanen, Sirkuu Jyrkkiö, Harri Sitho, Sebastian Eidt, Ugur Sahin, Heikki Joensuu

Cancer Res (2015) 75 (9_Supplement): P5-02-01.

https://doi.org/10.1158/1538-7445.SABCS14-P5-02-01

Published: 01 May 2015

View article titled, Abstract P5-02-01: Comparison of ESR1, PGR, HER2 and KI67 expression by central IHC and MammaTyper® RT-qPCR kit in the FinHer trial

Journal Articles

Abstract 869: PTEN/PI3K oncogenic pathway profiling informs an in vivo synergistic therapeutic model for basal-like breast cancer.

Lao H. Saal, Qing-Bai She, Sofia K. Gruvberger-Saal, Matthew Maurer, Mervi Jumppanen, Tao Su, Meaghan Dendy, Ying-Ka I. Lau, Lorenzo Memeo, Markus Ringner, Jorma Isola, Hanina Hibshoosh, Neal Rosen, Ramon Parsons

Cancer Res (2013) 73 (8_Supplement): 869.

https://doi.org/10.1158/1538-7445.AM2013-869

Published: 15 April 2013

View article titled, Abstract 869: PTEN/PI3K oncogenic pathway profiling informs an in vivo synergistic therapeutic model for basal-like breast cancer.

Journal Articles

3-Phosphoinositide–Dependent Kinase 1 Potentiates Upstream Lesions on the Phosphatidylinositol 3-Kinase Pathway in Breast Carcinoma

Cancer Res (2009) 69 (15): 6299–6306.

https://doi.org/10.1158/0008-5472.CAN-09-0820

Published: 29 July 2009

View article titled, 3-Phosphoinositide–Dependent Kinase 1 Potentiates Upstream Lesions on the Phosphatidylinositol 3-Kinase Pathway in Breast Carcinoma

Includes: Supplementary data

Journal Articles

Association of Wwox with ErbB4 in Breast Cancer

Rami I. Aqeilan, Valentina Donati, Eugenio Gaudio, Milena S. Nicoloso, Maria Sundvall, Anna Korhonen, Johan Lundin, Jorma Isola, Marius Sudol, Heikki Joensuu, Carlo M. Croce, Klaus Elenius

Cancer Res (2007) 67 (19): 9330–9336.

https://doi.org/10.1158/0008-5472.CAN-07-2147

Published: 01 October 2007

View article titled, Association of Wwox with ErbB4 in Breast Cancer

Includes: Supplementary data

Journal Articles

Development and evaluation of an automated, Web-based tool for quantitative assessment of fluorescence in situ hybridization

Juho Konsti, Jorma Isola, Mervi Laakso, Mikael Lundin, Johan Lundin

Cancer Res (2007) 67 (9_Supplement): 4412.

Published: 01 May 2007

View article titled, Development and evaluation of an automated, Web-based tool for quantitative assessment of fluorescence in situ hybridization

Journal Articles

Cleavable ErbB4 Isoform in Estrogen Receptor–Regulated Growth of Breast Cancer Cells

Teemu T. Junttila, Maria Sundvall, Mikael Lundin, Johan Lundin, Minna Tanner, Pirkko Härkönen, Heikki Joensuu, Jorma Isola, Klaus Elenius

Cancer Res (2005) 65 (4): 1384–1393.

https://doi.org/10.1158/0008-5472.CAN-04-3150

Published: 25 February 2005

View article titled, Cleavable ErbB4 Isoform in Estrogen Receptor–Regulated Growth of Breast Cancer Cells

Journal Articles

Decreased Accessibility and Lack of Activation of ErbB2 in JIMT-1, a Herceptin-Resistant, MUC4-Expressing Breast Cancer Cell Line

Peter Nagy, Elza Friedländer, Minna Tanner, Anita I. Kapanen, Kermit L. Carraway, Jorma Isola, Thomas M. Jovin

Cancer Res (2005) 65 (2): 473–482.

https://doi.org/10.1158/0008-5472.473.65.2

Published: 03 February 2005

View article titled, Decreased Accessibility and Lack of Activation of ErbB2 in JIMT-1, a Herceptin-Resistant, MUC4-Expressing Breast Cancer Cell Line

Journal Articles

Role of nuclear ErbB4 signaling in estrogen-regulated growth and prognosis of breast cancer.

Teemu T. Junttila, Maria Sundvall, Mirjami Mattila, Heikki Joensuu, Johan Lundin, Mikael Lundin, Minna Tanner, Jorma Isola, Pirkko Härkönen, Klaus Elenius

Cancer Res (2004) 64 (7_Supplement): 808.

Published: 01 April 2004

View article titled, Role of nuclear ErbB4 signaling in estrogen-regulated growth and prognosis of breast cancer.

Journal Articles

Patterns of Chromosomal Imbalances Defines Subgroups of Breast Cancer with Distinct Clinical Features and Prognosis. A Study of 305 Tumors by Comparative Genomic Hybridization

Karin Rennstam, Minna Ahlstedt-Soini, Bo Baldetorp, Pär-Ola Bendahl, Åke Borg, Ritva Karhu, Minna Tanner, Mika Tirkkonen, Jorma Isola

Cancer Res (2003) 63 (24): 8861–8868.

Published: 24 December 2003

View article titled, Patterns of Chromosomal Imbalances Defines Subgroups of Breast Cancer with Distinct Clinical Features and Prognosis. A Study of 305 Tumors by Comparative Genomic Hybridization

Journal Articles

Ski-related novel protein N (SnoN), a Negative Controller of Transforming Growth Factor-β Signaling, Is a Prognostic Marker in Estrogen Receptor-positive Breast Carcinomas,

Fan Zhang, Mikael Lundin, Ari Ristimäki, Päivi Heikkilä, Johan Lundin, Jorma Isola, Heikki Joensuu, Marikki Laiho

Cancer Res (2003) 63 (16): 5005–5010.

Published: 26 August 2003

View article titled, Ski-related novel protein N (SnoN), a Negative Controller of Transforming Growth Factor-β Signaling, Is a Prognostic Marker in Estrogen Receptor-positive Breast Carcinomas,

Includes: Supplementary data

Journal Articles

Haplo-insufficiency of BRCA1 in Sporadic Breast Cancer

Synnöve Staff, Jorma Isola, Minna Tanner

Cancer Res (2003) 63 (16): 4978–4983.

Published: 26 August 2003

View article titled, Haplo-insufficiency of BRCA1 in Sporadic Breast Cancer

Journal Articles

Few FH Mutations in Sporadic Counterparts of Tumor Types Observed in Hereditary Leiomyomatosis and Renal Cell Cancer Families

Maija Kiuru, Rainer Lehtonen, Johanna Arola, Reijo Salovaara, Heikki Järvinen, Kristiina Aittomäki, Jari Sjöberg, Tapio Visakorpi, Sakari Knuutila, Jorma Isola, Brett Delahunt, Riitta Herva, Virpi Launonen, Auli Karhu, Lauri A. Aaltonen

Cancer Res (2002) 62 (16): 4554–4557.

Published: 15 August 2002

View article titled, Few FH Mutations in Sporadic Counterparts of Tumor Types Observed in Hereditary Leiomyomatosis and Renal Cell Cancer Families

Journal Articles

Prognostic Significance of Elevated Cyclooxygenase-2 Expression in Breast Cancer

Ari Ristimäki, Anna Sivula, Johan Lundin, Mikael Lundin, Tiina Salminen, Caj Haglund, Heikki Joensuu, Jorma Isola

Cancer Res (2002) 62 (3): 632–635.

Published: 01 February 2002

View article titled, Prognostic Significance of Elevated Cyclooxygenase-2 Expression in Breast Cancer

Journal Articles

Amplification of HER-2/neu and Topoisomerase IIα in Primary and Metastatic Breast Cancer

Minna Tanner, Päivi Järvinen, Jorma Isola

Cancer Res (2001) 61 (14): 5345–5348.

Published: 01 July 2001

View article titled, Amplification of HER-2/neu and Topoisomerase IIα in Primary and Metastatic Breast Cancer

Journal Articles

Chromosomal Rearrangements and Oncogene Amplification Precede Aneuploidization in the Genetic Evolution of Breast Cancer

Karin Rennstam, Bo Baldetorp, Soili Kytölä, Minna Tanner, Jorma Isola

Cancer Res (2001) 61 (3): 1214–1219.

Published: 02 February 2001

View article titled, Chromosomal Rearrangements and Oncogene Amplification Precede Aneuploidization in the Genetic Evolution of Breast Cancer

Journal Articles

MYB Oncogene Amplification in Hereditary BRCA1 Breast Cancer

Päivikki Kauraniemi, Ingrid Hedenfalk, Karin Persson, David J. Duggan, Minna Tanner, Oskar Johannsson, Håkan Olsson, Jeffrey M. Trent, Jorma Isola, Åke Borg

Cancer Res (2000) 60 (19): 5323–5328.

Published: 01 October 2000

View article titled, MYB Oncogene Amplification in Hereditary BRCA1 Breast Cancer

Journal Articles

Distinct Somatic Genetic Changes Associated with Tumor Progression in Carriers of BRCA1 and BRCA2 Germ-line Mutations

Mika Tirkkonen, Oskar Johannsson, Bjarni A. Agnarsson, Håkan Olsson, Sigurdur Ingvarsson, Ritva Karhu, Minna Tanner, Jorma Isola, Rosa B. Barkardottir, Åke Borg, Olli-P. Kallioniemi

Cancer Res (1997) 57 (7): 1222–1227.

Published: 01 April 1997

View article titled, Distinct Somatic Genetic Changes Associated with Tumor Progression in Carriers of BRCA1 and BRCA2 Germ-line Mutations

Journal Articles

Genetic Heterogeneity and Clonal Evolution Underlying Development of Asynchronous Metastasis in Human Breast Cancer

Tuula Kuukasjärvi, Ritva Karhu, Minna Tanner, Marketta Kähkönen, Alejandro Schäffer, Nina Nupponen, Sari Pennanen, Anne Kallioniemi, Olli-Pekka Kallioniemi, Jorma Isola

Cancer Res (1997) 57 (8): 1597–1604.

Published: 01 April 1997

View article titled, Genetic Heterogeneity and Clonal Evolution Underlying Development of Asynchronous Metastasis in Human Breast Cancer

Journal Articles

Androgen Receptor Gene Amplification: A Possible Molecular Mechanism for Androgen Deprivation Therapy Failure in Prostate Cancer

Pasi Koivisto, Juha Kononen, Christian Palmberg, Teuvo Tammela, Eija Hyytinen, Jorma Isola, Jan Trapman, Kitty Cleutjens, Arjan Noordzij, Tapio Visakorpi, Olli-P. Kallioniemi

Cancer Res (1997) 57 (2): 314–319.

Published: 01 January 1997

View article titled, Androgen Receptor Gene Amplification: A Possible Molecular Mechanism for Androgen Deprivation Therapy Failure in Prostate Cancer

NARROW

Abstract 673: Exploration of tissue morphologies in breast cancer samples using unsupervised machine learning

Abstract P5-02-01: Comparison of ESR1, PGR, HER2 and KI67 expression by central IHC and MammaTyper® RT-qPCR kit in the FinHer trial

Abstract 869: PTEN/PI3K oncogenic pathway profiling informs an in vivo synergistic therapeutic model for basal-like breast cancer.

3-Phosphoinositide–Dependent Kinase 1 Potentiates Upstream Lesions on the Phosphatidylinositol 3-Kinase Pathway in Breast Carcinoma

Association of Wwox with ErbB4 in Breast Cancer

Development and evaluation of an automated, Web-based tool for quantitative assessment of fluorescence in situ hybridization

Cleavable ErbB4 Isoform in Estrogen Receptor–Regulated Growth of Breast Cancer Cells

Decreased Accessibility and Lack of Activation of ErbB2 in JIMT-1, a Herceptin-Resistant, MUC4-Expressing Breast Cancer Cell Line

Role of nuclear ErbB4 signaling in estrogen-regulated growth and prognosis of breast cancer.

Patterns of Chromosomal Imbalances Defines Subgroups of Breast Cancer with Distinct Clinical Features and Prognosis. A Study of 305 Tumors by Comparative Genomic Hybridization

Ski-related novel protein N (SnoN), a Negative Controller of Transforming Growth Factor-β Signaling, Is a Prognostic Marker in Estrogen Receptor-positive Breast Carcinomas,

Haplo-insufficiency of BRCA1 in Sporadic Breast Cancer

Few FH Mutations in Sporadic Counterparts of Tumor Types Observed in Hereditary Leiomyomatosis and Renal Cell Cancer Families

Prognostic Significance of Elevated Cyclooxygenase-2 Expression in Breast Cancer

Amplification of HER-2/neu and Topoisomerase IIα in Primary and Metastatic Breast Cancer

Chromosomal Rearrangements and Oncogene Amplification Precede Aneuploidization in the Genetic Evolution of Breast Cancer

MYB Oncogene Amplification in Hereditary BRCA1 Breast Cancer

Distinct Somatic Genetic Changes Associated with Tumor Progression in Carriers of BRCA1 and BRCA2 Germ-line Mutations

Genetic Heterogeneity and Clonal Evolution Underlying Development of Asynchronous Metastasis in Human Breast Cancer

Androgen Receptor Gene Amplification: A Possible Molecular Mechanism for Androgen Deprivation Therapy Failure in Prostate Cancer

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