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Jorge A. Carrasquillo
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Journal Articles

Abstract 2069: Initial PET imaging and pharmacokinetic results from a Phase I/II study of Zr-89-labeled anti-STEAP1 antibody in metastatic castrate-resistant prostate cancer (mCRPC) patients

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Jorge A. Carrasquillo, Daniel C. Danila, Volkan Beylergil, Joseph A. O'Donoghue, Sarah M. Cheal, Shutian Ruan, Neeta Pandit-Taskar, Josef J. Fox, Stephen E. Fleming, Pat B. Zanzonico, Govind Ragupathi, Serge K. Lyashchenko, Simon P. William, Steven M. Larson, Howard I. Scher, Bernard M. Fine, Michael J. Morris
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2069.
https://doi.org/10.1158/1538-7445.AM2014-2069
Published: 01 October 2014
View articletitled, Abstract 2069: Initial PET imaging and pharmacokinetic results from a Phase I/II study of Zr-89-labeled anti-STEAP1 antibody in metastatic castrate-resistant prostate cancer (mCRPC) patients
Journal Articles

The Anti-CD25 Monoclonal Antibody 7G7/B6, Armed with the α-Emitter 211At, Provides Effective Radioimmunotherapy for a Murine Model of Leukemia

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Meili Zhang, Zhengsheng Yao, Zhuo Zhang, Kayhan Garmestani, Vladimir S. Talanov, Paul S. Plascjak, Sarah Yu, Hyung-Sik Kim, Carolyn K. Goldman, Chang H. Paik, Martin W. Brechbiel, Jorge A. Carrasquillo, Thomas A. Waldmann
Journal: Cancer Research
Cancer Res (2006) 66 (16): 8227–8232.
https://doi.org/10.1158/0008-5472.CAN-06-1189
Published: 15 August 2006
View articletitled, The Anti-CD25 Monoclonal Antibody 7G7/B6, Armed with the α-Emitter 211At, Provides Effective Radioimmunotherapy for a Murine Model of Leukemia
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Journal Articles

Systemic radioimmunotherapy in synergy with vaccine renders antitumor effects in a preclinical model

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Mala Chakraborty, Alexander Gelbard, Jorge A. Carrasquillo, Sarah Yu, Marcelo Mamede, Chang H. Paik, Kevin Camphausen, Jeffrey Schlom, James W. Hodge
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 275.
Published: 15 April 2006
View articletitled, Systemic radioimmunotherapy in synergy with vaccine renders antitumor effects in a preclinical model
Journal Articles

Activating Fc Receptors Are Required for Antitumor Efficacy of the Antibodies Directed toward CD25 in a Murine Model of Adult T-Cell Leukemia

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Meili Zhang, Zhuo Zhang, Kayhan Garmestani, Carolyn K. Goldman, Jeffrey V. Ravetch, Martin W. Brechbiel, Jorge A. Carrasquillo, Thomas A. Waldmann
Journal: Cancer Research
Cancer Res (2004) 64 (16): 5825–5829.
https://doi.org/10.1158/0008-5472.CAN-04-1088
Published: 16 August 2004
View articletitled, Activating Fc Receptors Are Required for Antitumor Efficacy of the Antibodies Directed toward CD25 in a Murine Model of Adult T-Cell Leukemia
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Journal Articles

Preclinical evaluation of an anti-CD25 monoclonal antibody armed with an alpha emitter, At-211, as a potential radioimmunotherapeutic agent for leukemia and lymphoma

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Meili Zhang, Zhuo Zhang, Kayhan Garmestani, Hyung-Sik Kim, Carolyn K. Goldman, Chang Paik, Martin W. Brechbiel, Jorge A. Carrasquillo, Thomas A. Waldmann
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 956.
Published: 01 April 2004
View articletitled, Preclinical evaluation of an anti-CD25 monoclonal antibody armed with an alpha emitter, At-211, as a potential radioimmunotherapeutic agent for leukemia and lymphoma
Journal Articles

Radioimmunotherapy of A431 Xenografted Mice with Pretargeted B3 Antibody-Streptavidin and 90Y-labeled 1,4,7,10-Tetraazacyclododecane- N,N′,N″,N‴ -tetraacetic Acid (DOTA)-Biotin

Free
Zhengsheng Yao, Meili Zhang, Donald B. Axworthy, Karen J. Wong, Kayhan Garmestani, Luke Park, Chang W. Park, Robert W. Mallett, Louis J. Theodore, Eric K. Yau, Thomas A. Waldmann, Martin W. Brechbiel, Chang H. Paik, Ira Pastan, Jorge A. Carrasquillo
Journal: Cancer Research
Cancer Res (2002) 62 (20): 5755–5760.
Published: 15 October 2002
View articletitled, Radioimmunotherapy of A431 Xenografted Mice with Pretargeted B3 Antibody-Streptavidin and 90Y-labeled 1,4,7,10-Tetraazacyclododecane- N,N′,N″,N‴ -tetraacetic Acid (DOTA)-Biotin
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Journal Articles

Differences of Biodistribution, Pharmacokinetics, and Tumor Targeting between Interleukins 2 and 15

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Hisataka Kobayashi, Jorge A. Carrasquillo, Chang H. Paik, Thomas A. Waldmann, Yutaka Tagaya
Journal: Cancer Research
Cancer Res (2000) 60 (13): 3577–3583.
Published: 01 July 2000
View articletitled, Differences of Biodistribution, Pharmacokinetics, and Tumor Targeting between Interleukins 2 and 15
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Journal Articles

The Pharmacokinetic Characteristics of Glycolated Humanized Anti-Tac Fabs Are Determined by Their Isoelectric Points

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Hisataka Kobayashi, Nhat Le, In-sook Kim, Meyoung-Kon Kim, Jae-Eun Pie, Debra Drumm, David S. Paik, Thomas A. Waldmann, Chang H. Paik, Jorge A. Carrasquillo
Journal: Cancer Research
Cancer Res (1999) 59 (2): 422–430.
Published: 15 January 1999
View articletitled, The Pharmacokinetic Characteristics of Glycolated Humanized Anti-Tac Fabs Are Determined by Their Isoelectric Points
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Journal Articles

Aminosyn II Effectively Blocks Renal Uptake of 18F-labeled Anti-Tac Disulfide-stabilized Fv

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Jorge A. Carrasquillo, Lixin Lang, Millie Whatley, Peter Herscovitch, Qing-cheng Wang, Ira Pastan, William C. Eckelman
Journal: Cancer Research
Cancer Res (1998) 58 (12): 2612–2617.
Published: 01 June 1998
View articletitled, Aminosyn II Effectively Blocks Renal Uptake of 18F-labeled Anti-Tac Disulfide-stabilized Fv
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Journal Articles

Biodistribution of 125I-labeled Des(1–3) Insulin-like Growth Factor I in Tumor-bearing Nude Mice and Its in Vitro Catabolism

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Bao-Fu Sun, Hisataka Kobayashi, Nhat Le, Tae M. Yoo, Debra Drumm, Chang H. Paik, John G. McAfee, Jorge A. Carrasquillo
Journal: Cancer Research
Cancer Res (1997) 57 (13): 2754–2759.
Published: 01 July 1997
View articletitled, Biodistribution of 125I-labeled Des(1–3) Insulin-like Growth Factor I in Tumor-bearing Nude Mice and Its in Vitro Catabolism
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Journal Articles

Improved Biodistribution of 125I-labeled Anti-Tac Disulfide-stabilized Fv Fragment by Blocking Its Binding to the α Subunit of the Interleukin 2 Receptor in the Circulation with Preinjected Humanized Anti-Tac IgG

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Hisataka Kobayashi, Tae M. Yoo, Debra Drumm, Meyoung-Kon Kim, Bao-Fu Sun, Nhat Le, Keith O. Webber, Ira Pastan, Thomas A. Waldmann, Chang H. Paik, Jorge A. Carrasquillo
Journal: Cancer Research
Cancer Res (1997) 57 (10): 1955–1961.
Published: 01 May 1997
View articletitled, Improved Biodistribution of 125I-labeled Anti-Tac Disulfide-stabilized Fv Fragment by Blocking Its Binding to the α Subunit of the Interleukin 2 Receptor in the Circulation with Preinjected Humanized Anti-Tac IgG
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Journal Articles

L-Lysine Effectively Blocks Renal Uptake of 125I- or 99mTc-labeled Anti-Tac Disulfide-stabilized Fv Fragment

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Hisataka Kobayashi, Tae M. Yoo, In S. Kim, Meyoung-Kon Kim, Nhat Le, Keith O. Webber, Ira Pastan, Chang H. Paik, William C. Eckelman, Jorge A. Carrasquillo
Journal: Cancer Research
Cancer Res (1996) 56 (16): 3788–3795.
Published: 01 August 1996
View articletitled, L-Lysine Effectively Blocks Renal Uptake of 125I- or 99mTc-labeled Anti-Tac Disulfide-stabilized Fv Fragment
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Journal Articles

Improved Tumor Radioimmunodetection Using a Single-Chain Fv and γ-Interferon: Potential Clinical Applications for Radioimmunoguided Surgery and γ Scanning

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Carol A. Nieroda, Diane E. Milenic, Jorge A. Carrasquillo, Jeffrey Schlom, John W. Greiner
Journal: Cancer Research
Cancer Res (1995) 55 (13): 2858–2865.
Published: 01 July 1995
View articletitled, Improved Tumor Radioimmunodetection Using a Single-Chain Fv and γ-Interferon: Potential Clinical Applications for Radioimmunoguided Surgery and γ Scanning
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Journal Articles

Preclinical Evaluation of 111In-labeled B3 Monoclonal Antibody: Biodistribution and Imaging Studies in Nude Mice Bearing Human Epidermoid Carcinoma Xenografts

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Luigi Camera, Seigo Kinuya, Lee H. Pai, Kayhan Garmestani, Martin W. Brechbiel, Otto A. Gansow, Chang H. Paik, Ira Pastan, Jorge A. Carrasquillo
Journal: Cancer Research
Cancer Res (1993) 53 (12): 2834–2839.
Published: 01 June 1993
View articletitled, Preclinical Evaluation of 111In-labeled B3 Monoclonal Antibody: Biodistribution and Imaging Studies in Nude Mice Bearing Human Epidermoid Carcinoma Xenografts
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Journal Articles

Direct Intralymphatic Injection of Radiolabeled 111In-T101 in Patients with Cutaneous T-Cell Lymphoma

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James L. Mulshine, Jorge A. Carrasquillo, John N. Weinstein, Andrew M. Keenan, James C. Reynolds, Jean Herdt, Paul A. Bunn, Edward Sausville, Joyce Eddy, James D. Cotelingam, Patricia Perentesis, Carl Pinsky, Steven M. Larson
Journal: Cancer Research
Cancer Res (1991) 51 (2): 688–695.
Published: 01 January 1991
View articletitled, Direct Intralymphatic Injection of Radiolabeled 111In-T101 in Patients with Cutaneous T-Cell Lymphoma
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Journal Articles

Innovations That Influence the Pharmacology of Monoclonal Antibody Guided Tumor Targeting

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Jeffrey Schlom, Patricia Horan Hand, John W. Greiner, David Colcher, Shashi Shrivastav, Jorge A. Carrasquillo, James C. Reynolds, Steven M. Larson, Andrew Raubitschek
Journal: Cancer Research
Cancer Res (1990) 50 (3_Supplement): 820s–827s.
Published: 01 February 1990
View articletitled, Innovations That Influence the Pharmacology of Monoclonal Antibody Guided Tumor Targeting
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Journal Articles

Local Distribution and Concentration of Intravenously Injected 131I-9.2.27 Monoclonal Antibody in Human Malignant Melanoma

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Silvana Del Vecchio, James C. Reynolds, Jorge A. Carrasquillo, Ronald G. Blasberg, Ronald D. Neumann, Michael T. Lotze, Gail J. Bryant, Raymond J. Farkas, Steven M. Larson
Journal: Cancer Research
Cancer Res (1989) 49 (10): 2783–2789.
Published: 01 May 1989
View articletitled, Local Distribution and Concentration of Intravenously Injected 131I-9.2.27 Monoclonal Antibody in Human Malignant Melanoma
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Journal Articles

Measurement of Local Mr 97,000 and 250,000 Protein Antigen Concentration in Sections of Human Melanoma Tumor Using in Vitro Quantitative Autoradiography

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Silvana Del Vecchio, James C. Reynolds, Ronald G. Blasberg, Ronald D. Neumann, Jorge A. Carrasquillo, Ingegerd Hellström, Steven M. Larson
Journal: Cancer Research
Cancer Res (1988) 48 (19): 5475–5481.
Published: 01 October 1988
View articletitled, Measurement of Local Mr 97,000 and 250,000 Protein Antigen Concentration in Sections of Human Melanoma Tumor Using in Vitro Quantitative Autoradiography
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Journal Articles

Preclinical Studies on the Pharmacokinetic Properties of Human Monoclonal Antibodies to Colorectal Cancer and Their Use for Detection of Tumors

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Richard P. McCabe, Leona C. Peters, Martin V. Haspel, Nicholas Pomato, Jorge A. Carrasquillo, Michael G. Hanna, Jr.
Journal: Cancer Research
Cancer Res (1988) 48 (15): 4348–4353.
Published: 01 August 1988
View articletitled, Preclinical Studies on the Pharmacokinetic Properties of Human Monoclonal Antibodies to Colorectal Cancer and Their Use for Detection of Tumors
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Journal Articles

Immunolymphoscintigraphy and the Dose Dependence of 111In-labeled T101 Monoclonal Antibody in Patients with Cutaneous T-Cell Lymphoma

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Andrew M. Keenan, John N. Weinstein, Jorge A. Carrasquillo, Paul A. Bunn, Jr., James C. Reynolds, Kenneth A. Foon, Neil C. Smarte, Bimal Ghosh, Richard M. Fejka, Steven M. Larson, James L. Mulshine
Journal: Cancer Research
Cancer Res (1987) 47 (22): 6093–6099.
Published: 01 November 1987
View articletitled, Immunolymphoscintigraphy and the Dose Dependence of 111In-labeled T101 Monoclonal Antibody in Patients with Cutaneous T-Cell Lymphoma
Open the PDF for Immunolymphoscintigraphy and the Dose Dependence of 111In-labeled T101 Monoclonal Antibody in Patients with Cutaneous T-Cell Lymphoma in another window