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Jonna Frasor
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Journal Articles

Abstract 5753: Multi-omic analysis links neighborhood disadvantage to elevated stress hormones and tumorigenic markers in ER+ breast cancer patient plasma and tumor samples

Hannah Heath, Oana C. Danciu, Garth Rauscher, Natalie Pulliam, Elona Liko-Hazizi, Sarah Friedewald, Seema Khan, Julie Kim, William Gradishar, Jonna Frasor, Kent F. Hoskins, Zeynep Madak-Erdogan
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5753.
https://doi.org/10.1158/1538-7445.AM2025-5753
Published: 21 April 2025
View articletitled, Abstract 5753: Multi-omic analysis links neighborhood disadvantage to elevated stress hormones and tumorigenic markers in ER+ breast cancer patient plasma and tumor samples
Journal Articles

Abstract 5539: Single-cell and spatial approaches of identifying targets in endocrine therapy-resistant breast cancer

Svetlana E. Semina, Rosemary Huggins J. Huggins, Debra Tonetti, Kent Hoskins, Geoffrey L. Greene, Jonna Frasor, Jonathan Coloff
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5539.
https://doi.org/10.1158/1538-7445.AM2025-5539
Published: 21 April 2025
View articletitled, Abstract 5539: Single-cell and spatial approaches of identifying targets in endocrine therapy-resistant breast cancer
Journal Articles

Abstract 4757: Elucidating novel pro-apoptotic consequences of ceramides in endocrine therapy-resistant breast cancer

Purab Pal, Godwin K. Sarpey, G. Ekin Atilla-Gokcumen, Jonna Frasor, Jonathan L. Coloff
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4757.
https://doi.org/10.1158/1538-7445.AM2025-4757
Published: 21 April 2025
View articletitled, Abstract 4757: Elucidating novel pro-apoptotic consequences of ceramides in endocrine therapy-resistant breast cancer
Journal Articles

Abstract P4-02-06: Exploiting ceramide homeostasis to target endocrine therapy-resistant breast cancer

Purab Pal, Alec Millner, Ekin Atilla-Gokcumen, Jonna Frasor
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P4-02-06.
https://doi.org/10.1158/1538-7445.SABCS21-P4-02-06
Published: 15 February 2022
View articletitled, Abstract P4-02-06: Exploiting ceramide homeostasis to target endocrine therapy-resistant breast cancer
Journal Articles

Abstract P5-11-01: Identification of novel ER and ER-NFκB driven stem-like cell populations in ER+ breast cancer

Svetlana E. Semina, Mark Maienschein-Cline, Elaine T. Alarid, Carol A. Sartorius, Jonna Frasor
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-11-01.
https://doi.org/10.1158/1538-7445.SABCS21-P5-11-01
Published: 15 February 2022
View articletitled, Abstract P5-11-01: Identification of novel ER and ER-NFκB driven stem-like cell populations in ER+ breast cancer
Journal Articles

Abstract PS16-04: Estrogen receptor (ER) and NFkB activity determines cancer stem cell properties in ER positive breast cancer

Svetlana E. Semina, Irida Kastrati, Luis Alejo Cruz, Tara McCray, Mark Maienschein-Cline, Elaine T. Alarid, Jonna Frasor
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS16-04.
https://doi.org/10.1158/1538-7445.SABCS20-PS16-04
Published: 15 February 2021
View articletitled, Abstract PS16-04: Estrogen receptor (ER) and NFkB activity determines cancer stem cell properties in ER positive breast cancer
Journal Articles

Abstract 1176: Racial differences in circulating inflammatory cytokines and breast cancer disparities

Oana C. Danciu, George Chlipala, Zeynep Madak-Erdogan, Hariyali Patel, Landan Banks, Ayesha Zaidi, Ashlie Santaliz-Casiano, Lauren Schulte, Lauren Weller, Deanna Taiym, Natalie Pulliam, Elona Liko Hazizi, Elonia Martin, Anita Fareeduddin, Archana Bargaje, Carlos Garcia, Scott Hegerty, Sarah Friedewald, Seema Khan, J Julie Kim, William Gradishar, Garth Rauscher, Jonna Frasor, Kent F. Hoskins
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1176.
https://doi.org/10.1158/1538-7445.AM2020-1176
Published: 15 August 2020
View articletitled, Abstract 1176: Racial differences in circulating inflammatory cytokines and breast cancer disparities
Journal Articles

Abstract 2081: Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes

Linnea Hases, Rajitha Indukuri, Madeleine Birgersson, Trang Nguyen-Vu, Rodrigo Lozano, Ashish Saxena, Johan Hartman, Jonna Frasor, Jan-Åke Gustafsson, Pekka Katajisto, Amena Archer, Cecilia Williams
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2081.
https://doi.org/10.1158/1538-7445.AM2020-2081
Published: 15 August 2020
View articletitled, Abstract 2081: Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes
Journal Articles

Abstract 4208: Integrated molecular approach to identify biological factors contributing to breast cancer disparities in Chicago

Ashlie M. Santaliz Casiano, Zeynep Madak-Erdogan, Oana Danciu, Hariyali Patel, Landan Banks, Jermya Buckley, Garth Rauscher, Anita Fareeduddin, Elonia Martin, Archana Bargaje, Carlos Garcia, Lauren Schulte, Deanna Taiym, Julie Kim, William Gradishar, Scott Hegerty, Jonna Frasor, Kent Hoskins
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4208.
https://doi.org/10.1158/1538-7445.AM2019-4208
Published: 01 July 2019
View articletitled, Abstract 4208: Integrated molecular approach to identify biological factors contributing to breast cancer disparities in Chicago
Journal Articles

Abstract 5801: Unexpected selectivity of histone deacetylase inhibitors in live MDA-MD-231 triple-negative breast cancer cells

Shaimaa M. Aboukhatwa, Thomas W. Hanigan, Jayaprakash Neerasa, Taha Y. Taha, Nathan D. Brown, Eman E. El-Bastawissy, Mohamed A. Elkersh, Tarek F. El-Moselhy, Jonna Frasor, Pavel A. Petukhov
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5801.
https://doi.org/10.1158/1538-7445.AM2018-5801
Published: 01 July 2018
View articletitled, Abstract 5801: Unexpected selectivity of histone deacetylase inhibitors in live MDA-MD-231 triple-negative breast cancer cells
Journal Articles

Abstract 2158: Inhibition of NFkB restores tamoxifen responsiveness in resistant estrogen receptor positive breast cancer in a syngeneic mouse model

Emily Smart, Irida Kastrati, Jonna Frasor
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2158.
https://doi.org/10.1158/1538-7445.AM2018-2158
Published: 01 July 2018
View articletitled, Abstract 2158: Inhibition of NFkB restores tamoxifen responsiveness in resistant estrogen receptor positive breast cancer in a syngeneic mouse model
Journal Articles

Abstract 5242: NFĸB pathway activation is a key determinant of tamoxifen tolerance and recurrence in breast cancer

Irida Kastrati, Svitlana D. Brovkovych, Joshua D. Stender, Elaine T. Alarid, Jonna Frasor
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5242.
https://doi.org/10.1158/1538-7445.AM2018-5242
Published: 01 July 2018
View articletitled, Abstract 5242: NFĸB pathway activation is a key determinant of tamoxifen tolerance and recurrence in breast cancer
Journal Articles

Coactivation of Estrogen Receptor and IKKβ Induces a Dormant Metastatic Phenotype in ER-Positive Breast Cancer

Lamiaa El-Shennawy, Oleksii Dubrovskyi, Irida Kastrati, Jeanne M. Danes, Yiqun Zhang, Herbert E. Whiteley, Chad J. Creighton, Jonna Frasor
Journal: Cancer Research
Cancer Res (2018) 78 (4): 974–984.
https://doi.org/10.1158/0008-5472.CAN-17-1686
Published: 14 February 2018
View articletitled, Coactivation of Estrogen Receptor and IKKβ Induces a Dormant Metastatic Phenotype in ER-Positive Breast Cancer
Open the PDF for Coactivation of Estrogen Receptor and IKKβ Induces a Dormant Metastatic Phenotype in ER-Positive Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 4716: Dimethyl fumarate impairs breast cancer growth and inhibits the nuclear factor κB pathway in breast cancer cells by covalent modification of p65

Irida Kastrati, Marton I. Siklos, Esther L. Calderon-Gierszal, Gregory R. J. Thatcher, Jonna Frasor
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4716.
https://doi.org/10.1158/1538-7445.AM2016-4716
Published: 15 July 2016
View articletitled, Abstract 4716: Dimethyl fumarate impairs breast cancer growth and inhibits the nuclear factor κB pathway in breast cancer cells by covalent modification of p65
Journal Articles

Abstract 3104: Stapled peptide inhibitors of the estrogen receptor/steroid receptor coactivator interaction

Terry W. Moore, Thomas E. Speltz, Sean W. Fanning, Christopher G. Mayne, Jonna Frasor, Geoffrey L. Greene, Emad Tajkhorshid
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3104.
https://doi.org/10.1158/1538-7445.AM2016-3104
Published: 15 July 2016
View articletitled, Abstract 3104: Stapled peptide inhibitors of the estrogen receptor/steroid receptor coactivator interaction
Journal Articles

Abstract 4497: Design and synthesis of hybrid drugs to target inflammatory pathways in breast cancer

Irida Kastrati, Marton Siklos, Vladislav Litosh, Gregory Thatcher, Jonna Frasor
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4497.
https://doi.org/10.1158/1538-7445.AM2015-4497
Published: 01 August 2015
View articletitled, Abstract 4497: Design and synthesis of hybrid drugs to target inflammatory pathways in breast cancer
Journal Articles

Abstract 1866: Constitutively active NF-κB signaling switches estrogen receptor positive breast cancer cells from a proliferative to an invasive phenotype through luminal/basal plasticity

Lamiaa El-Shennawy, Jonna Frasor
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1866.
https://doi.org/10.1158/1538-7445.AM2015-1866
Published: 01 August 2015
View articletitled, Abstract 1866: Constitutively active NF-κB signaling switches estrogen receptor positive breast cancer cells from a proliferative to an invasive phenotype through luminal/basal plasticity
Journal Articles

Abstract LB-148: Inflammatory cytokines alter the sensitivity of breast cancer cells to endocrine treatments

Joshua D. Stender, Irida Kastrati, Maayan Yakir, Jonna Frasor, Christopher K. Glass
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-148.
https://doi.org/10.1158/1538-7445.AM2014-LB-148
Published: 01 October 2014
View articletitled, Abstract LB-148: Inflammatory cytokines alter the sensitivity of breast cancer cells to endocrine treatments
Journal Articles

Abstract 3732: New aspirin analogs for targeted therapy of ER+ breast cancers with activated NFkB inflammatory pathway

Irida Kastrati, Vladislav A. Litosh, Gregory R.J. Thatcher, Jonna Frasor
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3732.
https://doi.org/10.1158/1538-7445.AM2012-3732
Published: 15 April 2012
View articletitled, Abstract 3732: New aspirin analogs for targeted therapy of ER+ breast cancers with activated NFkB inflammatory pathway
Journal Articles

Abstract 3923: Growth hormone activates ERK via EGFR, not IGF-IR, to potentiate estrogen-dependent breast cancer cell proliferation

Dana L. Felice, Terry G. Unterman, Steven M. Swanson, Jonna Frasor
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3923.
https://doi.org/10.1158/1538-7445.AM2012-3923
Published: 15 April 2012
View articletitled, Abstract 3923: Growth hormone activates ERK via EGFR, not IGF-IR, to potentiate estrogen-dependent breast cancer cell proliferation