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Jonathan R. Dry
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Journal Articles

Abstract 225: Integration of patient-derived tumor organoids and patient clinical multimodal data to investigate the role of organoids in predicting treatment response

Kathleen A. Burke, Brian Larsen, Yi-Hung Carol Tan, Jessica Barbeau, Curtis Brinkman, Elle Moore, Nick Callamaras, Jonathan R. Dry, Iker Huerga, Kate Sasser, Jeffrey A. Borgia
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 225.
https://doi.org/10.1158/1538-7445.AM2024-225
Published: 22 March 2024
View article titled, Abstract 225: Integration of patient-derived tumor organoids and patient clinical multimodal data to investigate the role of organoids in predicting treatment response
Journal Articles

Abstract 6217: TP53 loss with whole genome doubling mediates heterogeneous intra-patient therapy response in EGFR-driven lung adenocarcinoma: A TRACERx study

Sebastijan Hobor, Maise Al Bakir, Marcin Skrzypski, Alexander M. Frankell, Bjorn Bakker, Thomas B. Watkins, Aleksandra Markovets, Jonathan R. Dry, Andrew P. Brown, Jasper van der Aart, Dahmane Oukrif, Marco Novelli, Matthew J. Renshaw, William Hill, Hilda van den Bos, Diana C. Spierings, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Elza de Bruin, Floris Foijer, Karen H. Vousden, TRACERx consortium, Robert E. Hynds, Crispin T. Hiley, Nnennaya Kanu, Simone Zaccaria, Eva C. Gronroos, Charles Swanton
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6217.
https://doi.org/10.1158/1538-7445.AM2022-6217
Published: 15 June 2022
View article titled, Abstract 6217: TP53 loss with whole genome doubling mediates heterogeneous intra-patient therapy response in EGFR-driven lung adenocarcinoma: A TRACERx study
Journal Articles

Pharmacological Inhibition of PARP6 Triggers Multipolar Spindle Formation and Elicits Therapeutic Effects in Breast Cancer

Zebin Wang, Shaun E. Grosskurth, Tony Cheung, Philip Petteruti, Jingwen Zhang, Xin Wang, Wenxian Wang, Farzin Gharahdaghi, Jiaquan Wu, Nancy Su, Ryan T. Howard, Michele Mayo, Dan Widzowski, David A. Scott, Jeffrey W. Johannes, Michelle L. Lamb, Deborah Lawson, Jonathan R. Dry, Paul D. Lyne, Edward W. Tate, Michael Zinda, Keith Mikule, Stephen E. Fawell, Corinne Reimer, Huawei Chen
Journal: Cancer Research
Cancer Res (2018) 78 (23): 6691–6702.
https://doi.org/10.1158/0008-5472.CAN-18-1362
Published: 03 December 2018
View article titled, Pharmacological Inhibition of PARP6 Triggers Multipolar Spindle Formation and Elicits Therapeutic Effects in Breast Cancer
Open the PDF for Pharmacological Inhibition of PARP6 Triggers Multipolar Spindle Formation and Elicits Therapeutic Effects in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 3886: A large cancer pharmacogenomics combination screen powering crowd-sourced advancement of computational drug synergy predictions

Jonathan R. Dry, Michael P. Menden, Krishna Bulusu, Justin Guinney, Julio Saez-Rodriguez
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3886.
https://doi.org/10.1158/1538-7445.AM2018-3886
Published: 01 July 2018
View article titled, Abstract 3886: A large cancer pharmacogenomics combination screen powering crowd-sourced advancement of computational drug synergy predictions
Journal Articles

Abstract 5724: Homologous recombination repair gene mutations for DNA repair and immune oncology drug combinations

Jonathan R. Dry, Zhongwu Lai, Brian Dougherty, Carl Barrett, Steven Criscione
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5724.
https://doi.org/10.1158/1538-7445.AM2018-5724
Published: 01 July 2018
View article titled, Abstract 5724: Homologous recombination repair gene mutations for DNA repair and immune oncology drug combinations
Journal Articles

PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models

Terrence F. Meehan, Nathalie Conte, Theodore Goldstein, Giorgio Inghirami, Mark A. Murakami, Sebastian Brabetz, Zhiping Gu, Jeffrey A. Wiser, Patrick Dunn, Dale A. Begley, Debra M. Krupke, Andrea Bertotti, Alejandra Bruna, Matthew H. Brush, Annette T. Byrne, Carlos Caldas, Amanda L. Christie, Dominic A. Clark, Heidi Dowst, Jonathan R. Dry, James H. Doroshow, Olivier Duchamp, Yvonne A. Evrard, Stephane Ferretti, Kristopher K. Frese, Neal C. Goodwin, Danielle Greenawalt, Melissa A. Haendel, Els Hermans, Peter J. Houghton, Jos Jonkers, Kristel Kemper, Tin O. Khor, Michael T. Lewis, K.C. Kent Lloyd, Jeremy Mason, Enzo Medico, Steven B. Neuhauser, James M. Olson, Daniel S. Peeper, Oscar M. Rueda, Je Kyung Seong, Livio Trusolino, Emilie Vinolo, Robert J. Wechsler-Reya, David M. Weinstock, Alana Welm, S. John Weroha, Frédéric Amant, Stefan M. Pfister, Marcel Kool, Helen Parkinson, Atul J. Butte, Carol J. Bult
Journal: Cancer Research
Cancer Res (2017) 77 (21): e62–e66.
https://doi.org/10.1158/0008-5472.CAN-17-0582
Published: 01 November 2017
View article titled, PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models
Open the PDF for PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models in another window
Includes: Multimedia, Supplementary data
Journal Articles

Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models

Catherine A. Eberlein, Daniel Stetson, Aleksandra A. Markovets, Katherine J. Al-Kadhimi, Zhongwu Lai, Paul R. Fisher, Catherine B. Meador, Paula Spitzler, Eiki Ichihara, Sarah J. Ross, Miika J. Ahdesmaki, Ambar Ahmed, Laura E. Ratcliffe, Elizabeth L. Christey O'Brien, Claire H. Barnes, Henry Brown, Paul D. Smith, Jonathan R. Dry, Garry Beran, Kenneth S. Thress, Brian Dougherty, William Pao, Darren A.E. Cross
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (12): 2489–2500.
https://doi.org/10.1158/0008-5472.CAN-14-3167
Published: 14 June 2015
View article titled, Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models
Open the PDF for Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models in another window
Includes: Supplementary data
Journal Articles

Abstract 4171: Integrating pan-molecular data sets by bimodality to nominate synthetic lethal gene pairs and biomarkers of drug response

Jonathan R. Dry, Mark Wappett, Ron Yang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4171.
https://doi.org/10.1158/1538-7445.AM2014-4171
Published: 01 October 2014
View article titled, Abstract 4171: Integrating pan-molecular data sets by bimodality to nominate synthetic lethal gene pairs and biomarkers of drug response
Journal Articles

Abstract 3497: Identifying pre-clinical predictive biomarkers for the PARP inhibitor olaparib

Jonathan R. Dry, Alan Lau, Charlotte Knights, Chris Harbron, John E. Prime, Lucy Riches, Rama Mangena, Tim Avis, Helen Brown, Sarah Runswick, Simon Dearden, Aisling O'Shaughnessy, L Unwin, Tim French, Darren Hodgson, Mark J. O'Connor
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3497.
https://doi.org/10.1158/1538-7445.AM10-3497
Published: 15 April 2010
View article titled, Abstract 3497: Identifying pre-clinical predictive biomarkers for the PARP inhibitor olaparib
Journal Articles

Transcriptional Pathway Signatures Predict MEK Addiction and Response to Selumetinib (AZD6244)

Jonathan R. Dry, Sandra Pavey, Christine A. Pratilas, Chris Harbron, Sarah Runswick, Darren Hodgson, Christine Chresta, Rose McCormack, Natalie Byrne, Mark Cockerill, Alexander Graham, Garry Beran, Andrew Cassidy, Carolyn Haggerty, Helen Brown, Gillian Ellison, Judy Dering, Barry S. Taylor, Mitchell Stark, Vanessa Bonazzi, Sugandha Ravishankar, Leisl Packer, Feng Xing, David B. Solit, Richard S. Finn, Neal Rosen, Nicholas K. Hayward, Tim French, Paul D. Smith
Journal: Cancer Research
Cancer Res (2010) 70 (6): 2264–2273.
https://doi.org/10.1158/0008-5472.CAN-09-1577
Published: 14 March 2010
View article titled, Transcriptional Pathway Signatures Predict MEK Addiction and Response to Selumetinib (AZD6244)
Open the PDF for Transcriptional Pathway Signatures Predict MEK Addiction and Response to Selumetinib (AZD6244) in another window
Includes: Supplementary data