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Jonathan Hickson
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Journal Articles

Abstract 741: Distinct functional effects of ILT family members in mediating the activity of an ILT2/ILT4/ILT5 cross-reactive monoclonal antibody in releasing the suppression on innate and adaptive anti-tumor immunity

Shiming Ye, Dong Zhang, Brenal Singh, Jaishree Bankoti, Diane Cohen, Siusze Tan, Donghee Choi, Jonathan Hickson, Min-Zu Wu, Urvi Kolhatkar, Mikhail Binnewies, Wei Jin, Jason Hall, John Engelhardt, Alexander Shoemaker
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 741.
https://doi.org/10.1158/1538-7445.AM2024-741
Published: 22 March 2024
View article titled, Abstract 741: Distinct functional effects of ILT family members in mediating the activity of an ILT2/ILT4/ILT5 cross-reactive monoclonal antibody in releasing the suppression on innate and adaptive anti-tumor immunity
Journal Articles

Abstract 1363: Blocking inhibitory receptor ILT3 by an antibody with enhanced Fc function promoted adaptive immunity against hematopoietic malignancy independent of ADCC

Shiming Ye, Dong Zhang, Min-Zu Wu, Harini Raghu, Diane Cohen, Mally Romero, Siu-Sze Tan, Donghee Choi, Jonathan Hickson, John Engelhardt, Alex Shoemaker
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1363.
https://doi.org/10.1158/1538-7445.AM2024-1363
Published: 22 March 2024
View article titled, Abstract 1363: Blocking inhibitory receptor ILT3 by an antibody with enhanced Fc function promoted adaptive immunity against hematopoietic malignancy independent of ADCC
Journal Articles

LRRC15 Is a Novel Mesenchymal Protein and Stromal Target for Antibody–Drug Conjugates

James W. Purcell, Sonia G. Tanlimco, Jonathan Hickson, Melvin Fox, Mien Sho, Lisa Durkin, Tamar Uziel, Rick Powers, Kelly Foster, Thomas McGonigal, Subashri Kumar, Josue Samayoa, Dong Zhang, Joann P. Palma, Sasmita Mishra, Diane Hollenbaugh, Kurt Gish, Susan E. Morgan-Lappe, Eric D. Hsi, Debra T. Chao
Journal: Cancer Research
Cancer Res (2018) 78 (14): 4059–4072.
https://doi.org/10.1158/0008-5472.CAN-18-0327
Published: 15 July 2018
View article titled, LRRC15 Is a Novel Mesenchymal Protein and Stromal Target for Antibody–Drug Conjugates
Open the PDF for LRRC15 Is a Novel Mesenchymal Protein and Stromal Target for Antibody–Drug Conjugates in another window
Includes: Supplementary data
Journal Articles

Abstract 953: LRRC15 is a novel antigen in sarcoma and the therapeutic target of the antibody-drug conjugate (ADC) ABBV-085

Eytan Ben-Ami, Ying Huang, Prafulla C. Gokhale, Benjamin Eschle, Lisa Durkin, Jonathan Hickson, Mien Sho, Susan Morgan-Lappe, Kurt Gish, Dominic W. Lai, Randy R. Robinson, Diane Hollenbaugh, Eric D. Hsi, Debra T. Chao, George D. Demetri, James W. Purcell
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 953.
https://doi.org/10.1158/1538-7445.AM2018-953
Published: 01 July 2018
View article titled, Abstract 953: LRRC15 is a novel antigen in sarcoma and the therapeutic target of the antibody-drug conjugate (ADC) ABBV-085
Journal Articles

Abstract 867: ABT-165 is a first-in-class therapeutic Dual Variable Domain Immunoglobulin (DVD-IgTM) that targets DLL4 and VEGF for the treatment of cancer

Yingchun Li, Jonathan Hickson, Dominic Ambrosi, Deanna Haasch, Kelly Foster-Duke, Lucia Eaton, Fang Jiang, Surekha Akella, Wenqing Gao, Sherry Ralston, Jijie Gu, Susan Morgan-Lappe
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 867.
https://doi.org/10.1158/1538-7445.AM2016-867
Published: 15 July 2016
View article titled, Abstract 867: ABT-165 is a first-in-class therapeutic Dual Variable Domain Immunoglobulin (DVD-Ig<sup>TM</sup>) that targets DLL4 and VEGF for the treatment of cancer
Journal Articles

The role of p38 activation in suppressing ovarian cancer metastatic colonization

Jennifer Taylor, Tamara Lotan, Jonathan Hickson, Kay Macleod, Russell Bainer, Yoav Gilad, Mark Lingen, S. Yamada, Carrie Rinker-Schaeffer
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1617.
Published: 01 May 2008
View article titled, The role of p38 activation in suppressing ovarian cancer metastatic colonization
Journal Articles

c-Jun NH2-Terminal Kinase Activating Kinase 1/Mitogen-Activated Protein Kinase Kinase 4–Mediated Inhibition of SKOV3ip.1 Ovarian Cancer Metastasis Involves Growth Arrest and p21 Up-regulation

Tamara Lotan, Jonathan Hickson, Jeffrey Souris, Dezheng Huo, Jennifer Taylor, Terry Li, Kristen Otto, Seiko Diane Yamada, Kay Macleod, Carrie W. Rinker-Schaeffer
Journal: Cancer Research
Cancer Res (2008) 68 (7): 2166–2175.
https://doi.org/10.1158/0008-5472.CAN-07-1568
Published: 01 April 2008
View article titled, c-Jun NH<sub>2</sub>-Terminal Kinase Activating Kinase 1/Mitogen-Activated Protein Kinase Kinase 4–Mediated Inhibition of SKOV3ip.1 Ovarian Cancer Metastasis Involves Growth Arrest and p21 Up-regulation
Open the PDF for c-Jun NH<sub>2</sub>-Terminal Kinase Activating Kinase 1/Mitogen-Activated Protein Kinase Kinase 4–Mediated Inhibition of SKOV3ip.1 Ovarian Cancer Metastasis Involves Growth Arrest and p21 Up-regulation in another window
Journal Articles

Mitogen-activated protein kinase kinase 4 (MKK4) mediated metastasis suppression of ovarian carcinoma occurs via a kinase-dependent mechanism and the p38 pathway.

Jonathan Hickson, Ron Tomek, Dezheng Huo, Carrie Rinker-Schaeffer, Diane Yamada
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 77.
Published: 01 May 2005
View article titled, Mitogen-activated protein kinase kinase 4 (MKK4) mediated metastasis suppression of ovarian carcinoma occurs via a kinase-dependent mechanism and the p38 pathway.