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Journal Articles

Abstract 6225: Tumor evolution through selection by ECM stiffness

Ting-Ching Wang, Suchitaa Sawhney, Daylin Morgan, Richa Rashmi, Marcos R. Estecio, Amy Brock, Irtisha Singh, Richard L. Bennett, Charles F. Baer, Jonathan D. Licht, Tanmay P. Lele

Cancer Res (2024) 84 (6_Supplement): 6225.

https://doi.org/10.1158/1538-7445.AM2024-6225

Published: 22 March 2024

View article titled, Abstract 6225: Tumor evolution through selection by ECM stiffness

Journal Articles

Abstract 4747: NSD2 mutation drives oncogenic programming in mantle cell lymphoma

Jianping Li, Marta Kulis, Alberto Riva, Heidi Casellas Román, Daphne Dupere-Richer, Amin Sobh, Charlotte Leonie Kaestner, Richard L. Bennett, Inaki Martin, Jonathan D. Licht

Cancer Res (2023) 83 (7_Supplement): 4747.

https://doi.org/10.1158/1538-7445.AM2023-4747

Published: 04 April 2023

View article titled, Abstract 4747: NSD2 mutation drives oncogenic programming in mantle cell lymphoma

Journal Articles

Abstract 4586: To define how the uvel melanoma-liver environment crosstalk shapes metastasis growth and therapeutic response

Sathya Neelature Sriramareddy, Zhihua Chen, Jiannong Li, Ann Chen, Jonathan D. Licht, J William Harbour, Keiran Smalley

Cancer Res (2023) 83 (7_Supplement): 4586.

https://doi.org/10.1158/1538-7445.AM2023-4586

Published: 04 April 2023

View article titled, Abstract 4586: To define how the uvel melanoma-liver environment crosstalk shapes metastasis growth and therapeutic response

Journal Articles

Abstract 4761: Identifying molecular targets to overcome CNS infiltration in acute lymphoblastic leukemia associated with an activating mutation of the NSD2 histone methyltransferase

Charlotte L. Kaestner, Amin Sobh, Jianping Li, Katelyn Raburn, Alberto Riva, Jason O. Brant, Richard L. Bennett, Jonathan D. Licht

Cancer Res (2023) 83 (7_Supplement): 4761.

https://doi.org/10.1158/1538-7445.AM2023-4761

Published: 04 April 2023

View article titled, Abstract 4761: Identifying molecular targets to overcome CNS infiltration in acute lymphoblastic leukemia associated with an activating mutation of the NSD2 histone methyltransferase

Journal Articles

Abstract 3935: CRISPR/Cas9 screens to identify proliferation and resistance mechanisms in uveal melanoma

Richard L. Bennett, Darby Monagle, Katelyn R. Raburn Smith, Amin Sobh, Keiran S. Smalley, J William Harbour, Jonathan D. Licht

Cancer Res (2023) 83 (7_Supplement): 3935.

https://doi.org/10.1158/1538-7445.AM2023-3935

Published: 04 April 2023

View article titled, Abstract 3935: CRISPR/Cas9 screens to identify proliferation and resistance mechanisms in uveal melanoma

Journal Articles

Abstract 3484: Oncohistone H2B-E76K alters gene expression & cellular phenotype in a bronchial epithelial cell line

Kimberly Espinoza Pereira, Richard L. Bennett, Jixiu Shan, Jay Sarthy, Jonathan D. Licht

Cancer Res (2023) 83 (7_Supplement): 3484.

https://doi.org/10.1158/1538-7445.AM2023-3484

Published: 04 April 2023

View article titled, Abstract 3484: Oncohistone H2B-E76K alters gene expression & cellular phenotype in a bronchial epithelial cell line

Journal Articles

Abstract B001: Elevated all-cause and cardiovascular mortality in cancer survivors with sarcopenia

Dejana Braithwaite, Shama Karanth, Christiaan Leeuwenburgh, Todd M. Manini, Meghann Wheeler, Danting Yang, Livingstone Aduse-Poke, Stephen Anton, Frank Penedo, Erin M. Siegel, Jonathan D. Licht, Dongyu Zhang

Cancer Res (2023) 83 (2_Supplement_1): B001.

https://doi.org/10.1158/1538-7445.AGCA22-B001

Published: 15 January 2023

View article titled, Abstract B001: Elevated all-cause and cardiovascular mortality in cancer survivors with sarcopenia

Journal Articles

Abstract 3719: Loss of Kmt2c, of the COMPASS-like complex, cooperates with oncogenic signaling in cancer

Gabriel Prado, Richard L. Bennett, Jonathan D. Licht

Cancer Res (2022) 82 (12_Supplement): 3719.

https://doi.org/10.1158/1538-7445.AM2022-3719

Published: 15 June 2022

View article titled, Abstract 3719: Loss of Kmt2c, of the COMPASS-like complex, cooperates with oncogenic signaling in cancer

Journal Articles

Abstract 4055: First in class multifunctional non classical antifolates inhibits thymidylate synthase and extends survival in pancreatic cancer model

Maria V. Guijarro, Patrick C. Kellish, Peter E. Dib, Nicholas G. Paciaroni, Akbar Nawab, Jacob Andring, Lidia Kulemina, Nicholas V. Borrero, Carlos Modenutti, Richard L. Bennett, Daniil Shabashvili, Jonathan D. Licht, Robert McKenna, Adrian Roitberg, Robert W. Huigens, Frederic J. Kaye, Maria Zajac-Kaye

Cancer Res (2022) 82 (12_Supplement): 4055.

https://doi.org/10.1158/1538-7445.AM2022-4055

Published: 15 June 2022

View article titled, Abstract 4055: First in class multifunctional non classical antifolates inhibits thymidylate synthase and extends survival in pancreatic cancer model

Journal Articles

Abstract 2117: Immunomodulatory functions of SMYD3 in HPV-negative head and neck squamous cell carcinoma

Nupur Nigam, Benjamin Jonah Bernard, Kyunghee Burkitt, Sohyoung Kim, Yvette Robbins, Richard L. Bennett, Jonathan D. Licht, Vassiliki Saloura

Cancer Res (2021) 81 (13_Supplement): 2117.

https://doi.org/10.1158/1538-7445.AM2021-2117

Published: 01 July 2021

View article titled, Abstract 2117: Immunomodulatory functions of SMYD3 in HPV-negative head and neck squamous cell carcinoma

Journal Articles

HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy

Michael F. Emmons, Fernanda Faião-Flores, Ritin Sharma, Ram Thapa, Jane L. Messina, Jurgen C. Becker, Dirk Schadendorf, Edward Seto, Vernon K. Sondak, John M. Koomen, Yian A. Chen, Eric K. Lau, Lixin Wan, Jonathan D. Licht, Keiran S.M. Smalley

Cancer Res (2019) 79 (11): 2947–2961.

https://doi.org/10.1158/0008-5472.CAN-19-0040

Published: 03 June 2019

View article titled, HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy

Includes: Supplementary data

Journal Articles

Abstract 2209: Deregulation of the Ras-Erk signaling axis modulates the enhancer landscape

Behnam Nabet, Pilib O Broin, Jaime Reyes, Kevin Shieh, Charles Y. Lin, Christine M. Will, Relja Popovic, Teresa Ezponda, James E. Bradner, Aaron A. Golden, Jonathan D. Licht

Cancer Res (2015) 75 (15_Supplement): 2209.

https://doi.org/10.1158/1538-7445.AM2015-2209

Published: 01 August 2015

View article titled, Abstract 2209: Deregulation of the Ras-Erk signaling axis modulates the enhancer landscape

Journal Articles

Abstract 5538: Development of HDACi resistance in DLBCL leads to a switch in subtype towards a more differentiated B-cell and is associated with increased sensitivity to proteasome inhibition

Daphné Dupéré-Richer, Mena Kinal, Filippa Pettersson, Mona Hassawi, Yang ShaoNing, Torsten H. Nielsen, Kathleen Klein, Teresa Ezponda-Itoiz, Jonathan D. Licht, Nathalie Johnson, Sarit E. Assouline, Leandro Cerchietti, Wilson H. Miller, Koren K. Mann

Cancer Res (2014) 74 (19_Supplement): 5538.

https://doi.org/10.1158/1538-7445.AM2014-5538

Published: 01 October 2014

View article titled, Abstract 5538: Development of HDACi resistance in DLBCL leads to a switch in subtype towards a more differentiated B-cell and is associated with increased sensitivity to proteasome inhibition

Journal Articles

Abstract 1127: MMSET: Can we flip the switch.

Christine Will, Michael Scholle, Roodolph St. Pierre, Ji Hyun Shim, Zhong Jun Cheng, Relja Popovic, Dinshaw J. Patel, James E. Bradner, Alex D. MacKerell, Milan Mrksich, Jonathan D. Licht

Cancer Res (2013) 73 (8_Supplement): 1127.

https://doi.org/10.1158/1538-7445.AM2013-1127

Published: 15 April 2013

View article titled, Abstract 1127: MMSET: Can we flip the switch.

Journal Articles

Abstract 740: Investigating the role of epigenetic mechanisms upon aberrant signaling network activation.

Behnam Nabet, Rosemary Braun, Relja Popovic, Jonathan D. Licht

Cancer Res (2013) 73 (8_Supplement): 740.

https://doi.org/10.1158/1538-7445.AM2013-740

Published: 15 April 2013

View article titled, Abstract 740: Investigating the role of epigenetic mechanisms upon aberrant signaling network activation.

Journal Articles

Abstract 2165: Sprouty loss leads to aberrant regulation of receptor tyrosine kinase signaling pathways and accelerates mammary tumorigenesis

Behnam Nabet, Alagarsamy L. Reddi, Priya Aggarwal, Marinka Bulic, Charuta Ambardekar, Barbara Canciani, Christine Will, Jonathan D. Licht

Cancer Res (2012) 72 (8_Supplement): 2165.

https://doi.org/10.1158/1538-7445.AM2012-2165

Published: 15 April 2012

View article titled, Abstract 2165: Sprouty loss leads to aberrant regulation of receptor tyrosine kinase signaling pathways and accelerates mammary tumorigenesis

Journal Articles

Abstract 1046: The histone methyl transferase MMSET/WHSC1 promotes an epithelial-mesenchymal transition and invasive properties of prostate cancer

Teresa Ezponda-Itoiz, Relja Popovic, Mrinal Y. Shah, Eva Martinez-Garcia, Dong-Joon Min, Christine Will, Jonathan D. Licht

Cancer Res (2012) 72 (8_Supplement): 1046.

https://doi.org/10.1158/1538-7445.AM2012-1046

Published: 15 April 2012

View article titled, Abstract 1046: The histone methyl transferase MMSET/WHSC1 promotes an epithelial-mesenchymal transition and invasive properties of prostate cancer

Journal Articles

Abstract 2136: Expression of fusion proteins in acute myeloid leukemia cells increases sensitivity to histone deacetylase inhibitors

Luca A. Petruccelli, Kim L. Rice, Filippa Pettersson, Jessica N. Nichol, Sophia Skoulikas, Jonathan D. Licht, Wilson H. Miller

Cancer Res (2011) 71 (8_Supplement): 2136.

https://doi.org/10.1158/1538-7445.AM2011-2136

Published: 15 April 2011

View article titled, Abstract 2136: Expression of fusion proteins in acute myeloid leukemia cells increases sensitivity to histone deacetylase inhibitors

Journal Articles

Abstract 1126: Gene expression profiling reveals that WT1 and WTX control cell growth through similar gene networks but different specific genes

Marianne K.H Kim, Dong J. Min, Mike Rabin, Jonathan D. Licht

Cancer Res (2010) 70 (8_Supplement): 1126.

https://doi.org/10.1158/1538-7445.AM10-1126

Published: 15 April 2010

View article titled, Abstract 1126: Gene expression profiling reveals that WT1 and WTX control cell growth through similar gene networks but different specific genes

Journal Articles

IFI16 is a novel WT1-associated protein identified by expression profiling in syndromic versus sporadic wilms tumors

Jacqueline M. Mason, Marianne Kh Kim, Chi-Ming Li, Windy Berkofsky-Fessler, Divaker Choubey, Paul E. Grundy, Benjamin Tycko, Jonathan D. Licht

Cancer Res (2006) 66 (8_Supplement): 933–934.

Published: 15 April 2006

View article titled, IFI16 is a novel WT1-associated protein identified by expression profiling in syndromic versus sporadic wilms tumors

NARROW

Abstract 6225: Tumor evolution through selection by ECM stiffness

Abstract 4747: NSD2 mutation drives oncogenic programming in mantle cell lymphoma

Abstract 4586: To define how the uvel melanoma-liver environment crosstalk shapes metastasis growth and therapeutic response

Abstract 4761: Identifying molecular targets to overcome CNS infiltration in acute lymphoblastic leukemia associated with an activating mutation of the NSD2 histone methyltransferase

Abstract 3935: CRISPR/Cas9 screens to identify proliferation and resistance mechanisms in uveal melanoma

Abstract 3484: Oncohistone H2B-E76K alters gene expression & cellular phenotype in a bronchial epithelial cell line

Abstract B001: Elevated all-cause and cardiovascular mortality in cancer survivors with sarcopenia

Abstract 3719: Loss of Kmt2c, of the COMPASS-like complex, cooperates with oncogenic signaling in cancer

Abstract 4055: First in class multifunctional non classical antifolates inhibits thymidylate synthase and extends survival in pancreatic cancer model

Abstract 2117: Immunomodulatory functions of SMYD3 in HPV-negative head and neck squamous cell carcinoma

HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy

Abstract 2209: Deregulation of the Ras-Erk signaling axis modulates the enhancer landscape

Abstract 5538: Development of HDACi resistance in DLBCL leads to a switch in subtype towards a more differentiated B-cell and is associated with increased sensitivity to proteasome inhibition

Abstract 1127: MMSET: Can we flip the switch.

Abstract 740: Investigating the role of epigenetic mechanisms upon aberrant signaling network activation.

Abstract 2165: Sprouty loss leads to aberrant regulation of receptor tyrosine kinase signaling pathways and accelerates mammary tumorigenesis

Abstract 1046: The histone methyl transferase MMSET/WHSC1 promotes an epithelial-mesenchymal transition and invasive properties of prostate cancer

Abstract 2136: Expression of fusion proteins in acute myeloid leukemia cells increases sensitivity to histone deacetylase inhibitors

Abstract 1126: Gene expression profiling reveals that WT1 and WTX control cell growth through similar gene networks but different specific genes

IFI16 is a novel WT1-associated protein identified by expression profiling in syndromic versus sporadic wilms tumors

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