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Jonas Dehairs
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Journal Articles

Abstract 3110: A clinically actionable lipid metabolic approach in potentiating the response to anti-androgen therapy in a castration resistant prostate cancer model

Free
Cynthia Sprenger, Silvia Rodrigues, Ali Talebi, Kathryn Soriano Epilepsia, Shihua Sun, Caroline Fidalgo Ribeiro, Fabio Socciarelli, Jonas Dehairs, Lisa Butler, Johannes V. Swinnen, Massimo Loda, Stephen Plymate
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3110.
https://doi.org/10.1158/1538-7445.AM2025-3110
Published: 21 April 2025
View articletitled, Abstract 3110: A clinically actionable lipid metabolic approach in potentiating the response to anti-androgen therapy in a castration resistant prostate cancer model
Journal Articles

ACSM1 and ACSM3 Regulate Fatty Acid Metabolism to Support Prostate Cancer Growth and Constrain Ferroptosis

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Raj K. Shrestha, Zeyad D. Nassar, Adrienne R. Hanson, Richard Iggo, Scott L. Townley, Jonas Dehairs, Chui Y. Mah, Madison Helm, Mohammadreza Alizadeh-Ghodsi, Marie Pickering, Bart Ghesquière, Matthew J. Watt, Lake-Ee Quek, Andrew J. Hoy, Wayne D. Tilley, Johannes V. Swinnen, Lisa M. Butler, Luke A. Selth
Journal: Cancer Research
Cancer Res (2024) 84 (14): 2313–2332.
https://doi.org/10.1158/0008-5472.CAN-23-1489
Published: 15 July 2024
View articletitled, ACSM1 and ACSM3 Regulate Fatty Acid Metabolism to Support Prostate Cancer Growth and Constrain Ferroptosis
Open the PDF for ACSM1 and ACSM3 Regulate Fatty Acid Metabolism to Support Prostate Cancer Growth and Constrain Ferroptosis in another window
Includes: Supplementary data
Journal Articles

Abstract A031: A fat lot of good: A novel monounsaturated fatty acid promotes prostate cancer growth and survival

Free
Julia S. Scott, Reuben Young, Swati Irani, Jonas Dehairs, Stephen Blanksby, Johannes V. Swinnen, Zeyad D. Nassar, Lisa M. Butler
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): A031.
https://doi.org/10.1158/1538-7445.PRCA2023-A031
Published: 02 June 2023
View articletitled, Abstract A031: A fat lot of good: A novel monounsaturated fatty acid promotes prostate cancer growth and survival
Journal Articles

Abstract 1157: Uncovering a novel role of peroxisomal β-oxidation in advanced, treatment-resistant prostate cancer

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Chui Yan Mah, An D. Nguyen, Takuto Niijima, Madison Helm, Jonas Dehairs, Feargal J. Ryan, Natalie Ryan, Ian G. Mills, Johannes V. Swinnen, David J. Lynn, Zeyad D. Nassar, Lisa M. Butler
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1157.
https://doi.org/10.1158/1538-7445.AM2023-1157
Published: 04 April 2023
View articletitled, Abstract 1157: Uncovering a novel role of peroxisomal β-oxidation in advanced, treatment-resistant prostate cancer
Journal Articles

Abstract C077: Evidence for a tumoral temperature driven chemoresistance pathway in pancreatic cancer

Free
Vincent de Laat, Halit Topal, Jonas Dehairs, Xander Spotbeen, Ali Talebi, Frank Vanderhoydonc, Tessa Ostyn, Tania Roskams, Baki Topal, Johan Swinnen
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): C077.
https://doi.org/10.1158/1538-7445.PANCA22-C077
Published: 15 November 2022
View articletitled, Abstract C077: Evidence for a tumoral temperature driven chemoresistance pathway in pancreatic cancer
Journal Articles

Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition

Free
Lisa M. Butler, Chui Yan Mah, Jelle Machiels, Andrew D. Vincent, Swati Irani, Shadrack M. Mutuku, Xander Spotbeen, Muralidhararao Bagadi, David Waltregny, Max Moldovan, Jonas Dehairs, Frank Vanderhoydonc, Katarzyna Bloch, Rajdeep Das, Jurgen Stahl, James G. Kench, Thomas Gevaert, Rita Derua, Etienne Waelkens, Zeyad D. Nassar, Luke A. Selth, Paul J. Trim, Marten F. Snel, David J. Lynn, Wayne D. Tilley, Lisa G. Horvath, Margaret M. Centenera, Johannes V. Swinnen
Journal: Cancer Research
Cancer Res (2021) 81 (19): 4981–4993.
https://doi.org/10.1158/0008-5472.CAN-20-3863
Published: 01 October 2021
View articletitled, Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition
Open the PDF for Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition in another window
Includes: Supplementary data
Journal Articles

Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis

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Lindsay A. Broadfield, João André Gonçalves Duarte, Roberta Schmieder, Dorien Broekaert, Koen Veys, Mélanie Planque, Kim Vriens, Yasuaki Karasawa, Francesco Napolitano, Suguru Fujita, Masashi Fujii, Miki Eto, Bryan Holvoet, Roman Vangoitsenhoven, Juan Fernandez-Garcia, Joke Van Elsen, Jonas Dehairs, Jia Zeng, James Dooley, Rebeca Alba Rubio, Jos van Pelt, Thomas G.P. Grünewald, Adrian Liston, Chantal Mathieu, Christophe M. Deroose, Johannes V. Swinnen, Diether Lambrechts, Diego di Bernardo, Shinya Kuroda, Katrien De Bock, Sarah-Maria Fendt
Journal: Cancer Research
Cancer Res (2021) 81 (8): 1988–2001.
https://doi.org/10.1158/0008-5472.CAN-20-1954
Published: 15 April 2021
View articletitled, Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis
Open the PDF for Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer

Free
Margaret M. Centenera, Julia S. Scott, Jelle Machiels, Zeyad D. Nassar, Deanna C. Miller, Irene Zinonos, Jonas Dehairs, Ingrid J.G. Burvenich, Giorgia Zadra, Paolo M. Chetta, Clyde Bango, Emma Evergren, Natalie K. Ryan, Joanna L. Gillis, Chui Yan Mah, Terence Tieu, Adrienne R. Hanson, Ryan Carelli, Katarzyna Bloch, Vasilios Panagopoulos, Etienne Waelkens, Rita Derua, Elizabeth D. Williams, Andreas Evdokiou, Anna Cifuentes-Rius, Nicolas H. Voelcker, Ian G. Mills, Wayne D. Tilley, Andrew M. Scott, Massimo Loda, Luke A. Selth, Johannes V. Swinnen, Lisa M. Butler
Journal: Cancer Research
Cancer Res (2021) 81 (7): 1704–1718.
https://doi.org/10.1158/0008-5472.CAN-20-2511
Published: 01 April 2021
View articletitled, ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer
Open the PDF for ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2076: Phospholipid profiling of clinical prostate tissues reveals targetable alterations in membrane lipid composition accompanying tumorigenesis

Free
Lisa M. Butler, Chui Yan Mah, Jonas Dehairs, Andrew Vincent, Shadrack Mutuku, Xander Spotbeen, Rajdeep Das, Zeyad Nassar, Luke Selth, Paul Trim, Marten Snel, David Lynn, Lisa Horvath, Wayne Tilley, Margaret Centenera, Johannes Swinnen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2076.
https://doi.org/10.1158/1538-7445.AM2020-2076
Published: 15 August 2020
View articletitled, Abstract 2076: Phospholipid profiling of clinical prostate tissues reveals targetable alterations in membrane lipid composition accompanying tumorigenesis