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Journal Articles

N-myc–Mediated Translation Control Is a Therapeutic Vulnerability in Medulloblastoma

Duygu Kuzuoglu-Ozturk, Ozlem Aksoy, Christin Schmidt, Robin Lea, Jon D. Larson, Ryan R.L. Phelps, Nicole Nasholm, Megan Holt, Adrian Contreras, Miller Huang, Shannon Wong-Michalak, Hao Shao, Robert Wechsler-Reya, Joanna J. Phillips, Jason E. Gestwicki, Davide Ruggero, William A. Weiss

Cancer Res (2023) 83 (1): 130–140.

https://doi.org/10.1158/0008-5472.CAN-22-0945

Published: 04 January 2023

View articletitled, N-myc–Mediated Translation Control Is a Therapeutic Vulnerability in Medulloblastoma

Includes: Supplementary data

Journal Articles

Abstract IA007: Transforming chromatin: Oncohistone mutations in pediatric high-grade glioma

Kaitlin Budd, Chang-Hyuk Kwon, Lawryn H. Kasper, Christopher Roberts, Jordan Roach, Jennifer Ocasio-Adorno, Jon D. Larson, Suzanne J. Baker

Cancer Res (2022) 82 (23_Supplement_2): IA007.

https://doi.org/10.1158/1538-7445.CancEpi22-IA007

Published: 01 December 2022

View articletitled, Abstract IA007: Transforming chromatin: Oncohistone mutations in pediatric high-grade glioma

Journal Articles

Abstract 6214: Detecting and characterizing extrachromosomal DNA in medulloblastoma at single-cell resolution

Owen Chapman, Sunita Sridhar, Jon D. Larson, Robert J. Wechsler-Reya, Jill Mesirov, Lukas Chavez

Cancer Res (2022) 82 (12_Supplement): 6214.

https://doi.org/10.1158/1538-7445.AM2022-6214

Published: 15 June 2022

View articletitled, Abstract 6214: Detecting and characterizing extrachromosomal DNA in medulloblastoma at single-cell resolution

Journal Articles

Abstract 95: The landscape of extrachromosomal circular DNA in medulloblastoma subgroups

Owen S. Chapman, Shanqing Wang, Jens Luebeck, Alexandra Garancher, Jon D. Larson, Joshua Lange, John Crawford, Scott L. Pomeroy, Paul Mischel, Ernest Fraenkel, Robert J. Wechsler-Reya, Vineet Bafna, Jill P. Mesirov, Lukas Chavez

Cancer Res (2021) 81 (13_Supplement): 95.

https://doi.org/10.1158/1538-7445.AM2021-95

Published: 01 July 2021

View articletitled, Abstract 95: The landscape of extrachromosomal circular DNA in medulloblastoma subgroups

Journal Articles

Abstract 6144: St. Jude Pediatric Brain Tumor Portal: Cloud-based resource for patient-derived orthotopic xenograft (PDOX) models of pediatric high-grade glioma, ependymoma, and CNS embryonal tumors

Cancer Res (2020) 80 (16_Supplement): 6144.

https://doi.org/10.1158/1538-7445.AM2020-6144

Published: 15 August 2020

View articletitled, Abstract 6144: St. Jude Pediatric Brain Tumor Portal: Cloud-based resource for patient-derived orthotopic xenograft (PDOX) models of pediatric high-grade glioma, ependymoma, and CNS embryonal tumors

Journal Articles

Abstract LB-289: Genomic instability and the development of high-grade gliomas

Lee J. Pribyl, Susanna M. Downing, Cristel V. Camacho, Jon D. Larson, Suzanne J. Baker, Peter J. McKinnon

Cancer Res (2019) 79 (13_Supplement): LB-289.

https://doi.org/10.1158/1538-7445.AM2019-LB-289

Published: 01 July 2019

View articletitled, Abstract LB-289: Genomic instability and the development of high-grade gliomas

Journal Articles

Sleeping Beauty Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors

Cancer Res (2019) 79 (5): 905–917.

https://doi.org/10.1158/0008-5472.CAN-18-1261

Published: 01 March 2019

View articletitled, Sleeping Beauty Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors

Includes: Supplementary data

Journal Articles

Abstract 2264: RNA sequencing based analysis of transposon-induced tumors reveals novel insights into cancer pathogenesis and progression

Emily T. Camilleri, Pauli J. Beckmann, Jon D. Larson, Morito Kurata, Jingmin Shu, Emily Pope, Wendy A. Hudson, Nuri A. Temiz, Susan K. Rathe, Rebecca S. LaRue, Anne E. Sarver, Milcah C. Scott, Jyotika Varshney, Jaime F. Modiano, Branden S. Moriarity, Aaron L. Sarver, Somasekar Seshagiri, David A. Largaespada

Cancer Res (2018) 78 (13_Supplement): 2264.

https://doi.org/10.1158/1538-7445.AM2018-2264

Published: 01 July 2018

View articletitled, Abstract 2264: RNA sequencing based analysis of transposon-induced tumors reveals novel insights into cancer pathogenesis and progression

Journal Articles

Abstract 3006: Oncogenic activity of H3.3 K27M in a spontaneous DIPG mouse model

Jon D. Larson, Lawryn H. Kasper, Gang Wu, Yiping Fan, David Finkelstein, Hongjian Jin, Barbara S. Paugh, Andre B. Silveira, Beisi Xu, Xiaoyan Zhu, Junyuan Zhang, Helen R. Russell, Peter J. McKinnon, David W. Ellison, Jinghui Zhang, Suzanne J. Baker

Cancer Res (2017) 77 (13_Supplement): 3006.

https://doi.org/10.1158/1538-7445.AM2017-3006

Published: 01 July 2017

View articletitled, Abstract 3006: Oncogenic activity of H3.3 K27M in a spontaneous DIPG mouse model

Journal Articles

PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation

Guo Zhu, Sherri L. Rankin, Jon D. Larson, Xiaoyan Zhu, Lionel M.L. Chow, Chunxu Qu, Jinghui Zhang, David W. Ellison, Suzanne J. Baker

Cancer Res (2017) 77 (1): 123–133.

https://doi.org/10.1158/0008-5472.CAN-16-1991

Published: 02 January 2017

View articletitled, PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation

Includes: Supplementary data

Journal Articles

Abstract IA26: Oncogenic mechanisms in diffuse intrinsic pontine gliomas

Andre B. Silveira, Lawryn H. Kasper, Jon D. Larson, Xiaoyan Zhu, Alexander K. Diaz, Suzanne J. Baker

Cancer Res (2016) 76 (5_Supplement): IA26.

https://doi.org/10.1158/1538-7445.PEDCA15-IA26

Published: 04 April 2016

View articletitled, Abstract IA26: Oncogenic mechanisms in diffuse intrinsic pontine gliomas

Journal Articles

Abstract B01: Biological consequences of histone mutations in the mammalian brain

Jon D. Larson, Lawryn H. Kasper, Helen R. Russell, Chunxu Qu, Xiaoyan Zhu, Peter J. McKinnon, Suzanne J. Baker

Cancer Res (2016) 76 (2_Supplement): B01.

https://doi.org/10.1158/1538-7445.CHROMEPI15-B01

Published: 14 January 2016

View articletitled, Abstract B01: Biological consequences of histone mutations in the mammalian brain

Journal Articles

Abstract IA14: The unique genomic landscape of pediatric high-grade glioma

Jon D. Larson, Andre B. Silveira, Lawryn H. Kasper, Helen R. Russell, Chunxu Qu, Peter J. McKinnon, Suzanne J. Baker

Cancer Res (2015) 75 (23_Supplement): IA14.

https://doi.org/10.1158/1538-7445.BRAIN15-IA14

Published: 09 December 2015

View articletitled, Abstract IA14: The unique genomic landscape of pediatric high-grade glioma

Journal Articles

Abstract A15: Variant histone H3 mutations associate with histone modification, DNA methylation, and gene expression changes in pediatric high-grade gliomas

Jon D. Larson, Troy A. McEachron, Chunxu Qu, Xiaoyan Zhu, Alexander K. Diaz, David W. Ellison, Brent A. Orr, Suzanne J. Baker

Cancer Res (2013) 73 (13_Supplement): A15.

https://doi.org/10.1158/1538-7445.CEC13-A15

Published: 13 May 2014

View articletitled, Abstract A15: Variant histone H3 mutations associate with histone modification, DNA methylation, and gene expression changes in pediatric high-grade gliomas

Journal Articles

Sleeping Beauty–Mediated Somatic Mutagenesis Implicates CSF1 in the Formation of High-Grade Astrocytomas

Aaron M. Bender, Lara S. Collier, Fausto J. Rodriguez, Christina Tieu, Jon D. Larson, Chandralekha Halder, Eric Mahlum, Thomas M. Kollmeyer, Keiko Akagi, Gobinda Sarkar, David A. Largaespada, Robert B. Jenkins

Cancer Res (2010) 70 (9): 3557–3565.

https://doi.org/10.1158/0008-5472.CAN-09-4674

Published: 28 April 2010

View articletitled, Sleeping Beauty–Mediated Somatic Mutagenesis Implicates CSF1 in the Formation of High-Grade Astrocytomas

Includes: Supplementary data

Journal Articles

De novo Induction of Genetically Engineered Brain Tumors in Mice Using Plasmid DNA

Stephen M. Wiesner, Stacy A. Decker, Jon D. Larson, Katya Ericson, Colleen Forster, Jose L. Gallardo, Chunmei Long, Zachary L. Demorest, Edward A. Zamora, Walter C. Low, Karen SantaCruz, David A. Largaespada, John R. Ohlfest

Cancer Res (2009) 69 (2): 431–439.

https://doi.org/10.1158/0008-5472.CAN-08-1800

Published: 15 January 2009

View articletitled, De novo Induction of Genetically Engineered Brain Tumors in Mice Using Plasmid DNA

Includes: Supplementary data

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N-myc–Mediated Translation Control Is a Therapeutic Vulnerability in Medulloblastoma

Abstract IA007: Transforming chromatin: Oncohistone mutations in pediatric high-grade glioma

Abstract 6214: Detecting and characterizing extrachromosomal DNA in medulloblastoma at single-cell resolution

Abstract 95: The landscape of extrachromosomal circular DNA in medulloblastoma subgroups

Abstract 6144: St. Jude Pediatric Brain Tumor Portal: Cloud-based resource for patient-derived orthotopic xenograft (PDOX) models of pediatric high-grade glioma, ependymoma, and CNS embryonal tumors

Abstract LB-289: Genomic instability and the development of high-grade gliomas

Sleeping Beauty Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors

Abstract 2264: RNA sequencing based analysis of transposon-induced tumors reveals novel insights into cancer pathogenesis and progression

Abstract 3006: Oncogenic activity of H3.3 K27M in a spontaneous DIPG mouse model

PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation

Abstract IA26: Oncogenic mechanisms in diffuse intrinsic pontine gliomas

Abstract B01: Biological consequences of histone mutations in the mammalian brain

Abstract IA14: The unique genomic landscape of pediatric high-grade glioma

Abstract A15: Variant histone H3 mutations associate with histone modification, DNA methylation, and gene expression changes in pediatric high-grade gliomas

Sleeping Beauty–Mediated Somatic Mutagenesis Implicates CSF1 in the Formation of High-Grade Astrocytomas

De novo Induction of Genetically Engineered Brain Tumors in Mice Using Plasmid DNA

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