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Joji Nagasaki
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Journal Articles

Myeloid Cells Induce Infiltration and Activation of B Cells and CD4+ T Follicular Helper Cells to Sensitize Brain Metastases to Combination Immunotherapy

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Toshifumi Ninomiya, Naoya Kemmotsu, Fumiaki Mukohara, Masaki Magari, Ai Miyamoto, Youki Ueda, Takamasa Ishino, Joji Nagasaki, Tomohiro Fujiwara, Hidetaka Yamamoto, Hidetoshi Hayashi, Kota Tachibana, Joji Ishida, Yoshihiro Otani, Shota Tanaka, Shinichi Toyooka, Isamu Okamoto, Yosuke Togashi
Journal: Cancer Research
Cancer Res (2025) 85 (6): 1082–1096.
https://doi.org/10.1158/0008-5472.CAN-24-2274
Published: 14 March 2025
View articletitled, Myeloid Cells Induce Infiltration and Activation of B Cells and CD4+ T Follicular Helper Cells to Sensitize Brain Metastases to Combination Immunotherapy
Open the PDF for Myeloid Cells Induce Infiltration and Activation of B Cells and CD4+ T Follicular Helper Cells to Sensitize Brain Metastases to Combination Immunotherapy in another window
Includes: Supplementary data
Journal Articles

CD106 in Tumor-Specific Exhausted CD8+ T Cells Mediates Immunosuppression by Inhibiting TCR Signaling

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Yuto Naoi, Takao Morinaga, Joji Nagasaki, Ryo Ariyasu, Youki Ueda, Kazuo Yamashita, Wenhao Zhou, Shusuke Kawashima, Katsushige Kawase, Akiko Honobe-Tabuchi, Takehiro Ohnuma, Tatsuyoshi Kawamura, Yoshiyasu Umeda, Yu Kawahara, Yasuhiro Nakamura, Yukiko Kiniwa, Osamu Yamasaki, Satoshi Fukushima, Masahito Kawazu, Yutaka Suzuki, Hiroyoshi Nishikawa, Toyoyuki Hanazawa, Mizuo Ando, Takashi Inozume, Yosuke Togashi
Journal: Cancer Research
Cancer Res (2024) 84 (13): 2109–2122.
https://doi.org/10.1158/0008-5472.CAN-23-0453
Published: 02 July 2024
View articletitled, CD106 in Tumor-Specific Exhausted CD8+ T Cells Mediates Immunosuppression by Inhibiting TCR Signaling
Open the PDF for CD106 in Tumor-Specific Exhausted CD8+ T Cells Mediates Immunosuppression by Inhibiting TCR Signaling in another window
Includes: Supplementary data
Journal Articles

Abstract 7536: CD4+T cell exhaustion in the tumor microenvironment and antitumor immunity

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Joji Nagasaki, Wenhao Zhou, Shusuke Kawashima, Takamasa Ishino, Katsushige Kawase, Youki Ueda, Kazuo Yamashita, Tomofumi Watanabe, Takashi Inozume, Yosuke Togashi
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7536.
https://doi.org/10.1158/1538-7445.AM2024-7536
Published: 22 March 2024
View articletitled, Abstract 7536: CD4+T cell exhaustion in the tumor microenvironment and antitumor immunity
Journal Articles

Abstract 707: High major histocompatibility complex class I expression overcomes cancer immunotherapy resistance due to interferon gamma signaling pathway defects

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Katsushige Kawase, Shusuke Kawashima, Joji Nagasaki, Takashi Inozume, Hiromasa Yamamoto, Masahito Kawazu, Toyoyuki Hanazawa, Yosuke Togashi
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 707.
https://doi.org/10.1158/1538-7445.AM2023-707
Published: 04 April 2023
View articletitled, Abstract 707: High major histocompatibility complex class I expression overcomes cancer immunotherapy resistance due to interferon gamma signaling pathway defects
Journal Articles

Abstract 1099: Combined treatment with direct hydrogen peroxide administration and irradiation promotes an abscopal effect in mouse models

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Naoya Kemmotsu, Li zhu, Youki Ueda, Hiromichi Dansako, Shinichi Toyooka, Joji Nagasaki, Yosuke Togashi
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1099.
https://doi.org/10.1158/1538-7445.AM2023-1099
Published: 04 April 2023
View articletitled, Abstract 1099: Combined treatment with direct hydrogen peroxide administration and irradiation promotes an abscopal effect in mouse models