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Joji Kitayama
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Journal Articles

Abstract 3830: The enhanced formation of neutrophil extracellular traps (NETs) contributes to peritoneal and hepatic metastasis in diabetic conditions

Rei Takahashi, Hideyo Miyato, Akira Saito, Eri Suizu, Misaki Matsumiya, Hirofumi Sonoda, Hideyuki Ohzawa, Hironori Yamaguchi, Naohiro Sata, Joji Kitayama
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3830.
https://doi.org/10.1158/1538-7445.AM2025-3830
Published: 21 April 2025
View articletitled, Abstract 3830: The enhanced formation of neutrophil extracellular traps (NETs) contributes to peritoneal and hepatic metastasis in diabetic conditions
Journal Articles

Abstract 5286: The acquisition of CD11a via trogocytosis by gastric cancer cells after contact with T cells increases adhesion to endothelial cells

Hideyo Miyato, Eri Suizu, Rei Takahashi, Misaki Matsumiya, Hirofumi Sonoda, Hideyuki Ozawa, Hironori Yamaguchi, Naohiro Sata, Joji Kitayama
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5286.
https://doi.org/10.1158/1538-7445.AM2025-5286
Published: 21 April 2025
View articletitled, Abstract 5286: The acquisition of CD11a via trogocytosis by gastric cancer cells after contact with T cells increases adhesion to endothelial cells
Journal Articles

Abstract LB264: Intracavitary gene therapy using miRNA-29b-encoding adeno-associated virus for peritoneal dissemination

Yuki Kaneko, Hideyuki Ohzawa, Yuki Kimura, Rei Takahashi, Misaki Matsumiya, Kohei Tamura, Yurie Futoh, Hideyo Miyato, Ryota Watano, Hiroaki Mizukami, Naohiro Sata, Joji Kitayama
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB264.
https://doi.org/10.1158/1538-7445.AM2024-LB264
Published: 05 April 2024
View articletitled, Abstract LB264: Intracavitary gene therapy using miRNA-29b-encoding adeno-associated virus for peritoneal dissemination
Journal Articles

Abstract 1491: The enhanced formation of neutrophil extracellular traps (NETs) may contribute to the exacerbation of peritoneal metastasis in a diabetic host

Rei Takahashi, Hideyuki Ohzawa, Yuki Kaneko, Misaki Matsumiya, Yurie Futoh, Kohei Tamura, Kazuya Takahashi, Yuki Kimura, Akira Saito, Hideyo Miyato, Naohiro Sata, Joji Kitayama
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1491.
https://doi.org/10.1158/1538-7445.AM2024-1491
Published: 22 March 2024
View articletitled, Abstract 1491: The enhanced formation of neutrophil extracellular traps (NETs) may contribute to the exacerbation of peritoneal metastasis in a diabetic host
Journal Articles

Abstract 635: Effects of vagus nerve signals on the development of peritoneal metastasis of murine gastric cancer

Yurie Futoh, Hideyo Miyato, Misaki Matsumiya, Rei Takahashi, Yuki Kaneko, Kazuya Takahashi, Yuki Kimura, Hiroko Hayakawa, Hideyuki Ohzawa, Naohiro Sata, Joji Kitayama
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 635.
https://doi.org/10.1158/1538-7445.AM2023-635
Published: 04 April 2023
View articletitled, Abstract 635: Effects of vagus nerve signals on the development of peritoneal metastasis of murine gastric cancer
Journal Articles

Abstract 2266: Tumor associated neutrophils (TAN) may produce neutrophil extracellular traps (NETs) which can suppress the infiltration of activated T cells in tumor tissue

Kohei Tamura, Hideyo Miyato, Misaki Matsumiya, Rei Takahashi, Yuki Kaneko, Yurie Futoh, Kazuya Takahashi, Yuki Kimura, Akira Saito, Hideyuki Ohzawa, Yasushi Saga, Yuji Takei, Hiroyuki Fujiwara, Joji Kitayama
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2266.
https://doi.org/10.1158/1538-7445.AM2023-2266
Published: 04 April 2023
View articletitled, Abstract 2266: Tumor associated neutrophils (TAN) may produce neutrophil extracellular traps (NETs) which can suppress the infiltration of activated T cells in tumor tissue
Journal Articles

Abstract 1268: The effect of metformin for neutrophil extracellular traps (NETs) on tumor immune microenvironment of colorectal cancer with type 2 diabetes mellitus

Akira Saito, Hideyuki Ohzawa, Yuki Kaneko, Kohei Tamura, Yurie Futoh, Kazuya Takahashi, Yuki Kimura, Rie Kawashima, Hideyo Miyato, Joji Kitayama, Naohiro Sata
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1268.
https://doi.org/10.1158/1538-7445.AM2023-1268
Published: 04 April 2023
View articletitled, Abstract 1268: The effect of metformin for neutrophil extracellular traps (NETs) on tumor immune microenvironment of colorectal cancer with type 2 diabetes mellitus
Journal Articles

Abstract 6289: Activated neutrophils induce robust mesenchymal migration of gastric cancer cells

Kazuya Takahashi, Hideyuki Ohzawa, Yuki Kaneko, Yurie Futoh, Kohei Tamura, Yuki Kimura, Akira Saito, Mineyuki Tojo, Rihito Kanamaru, Hideyo Miyato, Naohiro Sata, Joji Kitayama
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6289.
https://doi.org/10.1158/1538-7445.AM2022-6289
Published: 15 June 2022
View articletitled, Abstract 6289: Activated neutrophils induce robust mesenchymal migration of gastric cancer cells
Journal Articles

Abstract 6309: Activated neutrophils inhibit chemotactic migration of activated T lymphocytes to CXCL11 by multiple mechanisms

Kohei Tamura, Yuki Kaneko, Yurie Futoh, Kazuya Takahashi, Yuki Kimura, Akira Saito, Mineyuki Tojo, Hideyo Miyato, Hideyuki Ohzawa, Yasushi Saga, Yuji Takei, Hiroyuki Fujiwara, Joji Kitayama
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6309.
https://doi.org/10.1158/1538-7445.AM2022-6309
Published: 15 June 2022
View articletitled, Abstract 6309: Activated neutrophils inhibit chemotactic migration of activated T lymphocytes to CXCL11 by multiple mechanisms
Journal Articles

Abstract 6284: Exosomal miR-29b derived from mesenchymal stem cell (MSC) may suppress peritoneal metastasis via the effects on peritoneal mesothelial cells

Yuki Kimura, Hideyuki Ohzawa, Yuki Kaneko, Kohei Tamura, Yurie Futoh, Kazuya Takahashi, Akira Saito, Mineyuki Tojo, Hideyo Miyato, Joji Kitayama
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6284.
https://doi.org/10.1158/1538-7445.AM2022-6284
Published: 15 June 2022
View articletitled, Abstract 6284: Exosomal miR-29b derived from mesenchymal stem cell (MSC) may suppress peritoneal metastasis via the effects on peritoneal mesothelial cells
Journal Articles

Abstract 6285: MicroRNA-217 affects tumor microenvironment and enhances the chemosensitivity of pancreatic cancer

Yuki Kaneko, HIdeyuki Ohzawa, Yuki Kimura, Kohei Tamura, Yurie Futoh, Kazuya Takahashi, Akira Saito, Mineyuki Tojo, Hideyo Miyato, Naohiro Sata, Joji Kitayama
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6285.
https://doi.org/10.1158/1538-7445.AM2022-6285
Published: 15 June 2022
View articletitled, Abstract 6285: MicroRNA-217 affects tumor microenvironment and enhances the chemosensitivity of pancreatic cancer
Journal Articles

Abstract 6379: Dipeptidyl peptidase-4 inhibitor impairs the outcomes of patients with type 2 diabetes mellitus after curative resection for colorectal cancer

Akira Saito, Hideyuki Ohzawa, Yuki Kaneko, Kohei Tamura, Yurie Futoh, Kazuya Takahashi, Yuki Kimura, Mineyuki Tojo, Rie Kawashima, Hideyo Miyato, Naohiro Sata, Joji Kitayama
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6379.
https://doi.org/10.1158/1538-7445.AM2022-6379
Published: 15 June 2022
View articletitled, Abstract 6379: Dipeptidyl peptidase-4 inhibitor impairs the outcomes of patients with type 2 diabetes mellitus after curative resection for colorectal cancer
Journal Articles

Abstract 6279: Combination of metformin and local irradiation efficiently provokes abscopal effects in a murine rectal cancer model

Mineyuki Tojo, Hideyo Miyato, Koji Koinuma, Hisanaga Horie, Hidenori Tsukui, Akira Saito, Yuki Kimura, Yuki Kaneko, Hideyuki Ohzawa, Hironori Yamaguchi, Alan Kawarai Lefor, Naohiro Sata, Joji Kitayama
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6279.
https://doi.org/10.1158/1538-7445.AM2022-6279
Published: 15 June 2022
View articletitled, Abstract 6279: Combination of metformin and local irradiation efficiently provokes abscopal effects in a murine rectal cancer model
Journal Articles

Abstract 2380: MiR29b may suppress peritoneal metastasis via the effects on peritoneal mesothelial cells

Yuki Kimura, Hideyuki Ohzawa, Yuki Kaneko, Yurie Futoh, Kohei Tamura, Kazuya Takahashi, Akira Saito, Mineyuki Tojo, Yuko Kumagai, Hideyo Miyato, Naohiro Sata, Joji Kitayama
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2380.
https://doi.org/10.1158/1538-7445.AM2021-2380
Published: 01 July 2021
View articletitled, Abstract 2380: MiR29b may suppress peritoneal metastasis via the effects on peritoneal mesothelial cells
Journal Articles

Abstract 2925: Metformin can induce abscopal effects of local irradiation and suppress the spontaneous lung metastases in murine colon cancer model

Mineyuki Tojo, Hidenori Tsukui, Akira Saito, Kouhei Tamura, Yuki Kaneko, Yurie Futoh, Yuki Kimura, Kazuya Takahashi, Yuko Kumagai, Hideyuki Ohzawa, Hideyo Miyato, Koji Koinuma, Hisanaga Horie, Naohiro Sata, Joji KItayama
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2925.
https://doi.org/10.1158/1538-7445.AM2021-2925
Published: 01 July 2021
View articletitled, Abstract 2925: Metformin can induce abscopal effects of local irradiation and suppress the spontaneous lung metastases in murine colon cancer model
Journal Articles

Abstract 3191: The effect of metformin on the tumor immune microenvironment

Akira Saito, Hideyuki Ohzawa, Yuki Kaneko, Kohei Tamura, Yurie Futoh, Kazuya Takahashi, Yuki Kimura, Mineyuki Tojo, Yuko Kumagai, Hideyo Miyato, Naohiro Sata, Joji Kitayama
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3191.
https://doi.org/10.1158/1538-7445.AM2021-3191
Published: 01 July 2021
View articletitled, Abstract 3191: The effect of metformin on the tumor immune microenvironment
Journal Articles

Abstract 6209: Monocytes phagocytose neutrophil extracellular traps (NETs) and differentiate into pro-inflammatory macrophages

Akira Saito, Hideyuki Ozawa, Kazuya Takahashi, Yuki Kimura, Mineyuki Tojo, Yuko Kumagai, Rihito Kanamaru, Hidenori Tsukui, Naohiro Sata, Joji Kitayama
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6209.
https://doi.org/10.1158/1538-7445.AM2020-6209
Published: 15 August 2020
View articletitled, Abstract 6209: Monocytes phagocytose neutrophil extracellular traps (NETs) and differentiate into pro-inflammatory macrophages
Journal Articles

Abstract 2524: MiR-29b may suppress peritoneal metastasis via the effects on peritoneal mesothelial cells as well as on tumor cells

Yuki Kimura, Hideyuki Ohzawa, Akira Saito, Naohiro Sata, Joji Kitayama
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2524.
https://doi.org/10.1158/1538-7445.AM2020-2524
Published: 15 August 2020
View articletitled, Abstract 2524: MiR-29b may suppress peritoneal metastasis via the effects on peritoneal mesothelial cells as well as on tumor cells
Journal Articles

Abstract 2258: CD73 targeting therapy enhances the anti-tumor effect of radiation therapy in rectal cancer

Hidenori Tsukui, Hisanaga Horie, Akira Saito, Koji Koinuma, Hideyuki Ohsawa, Hironori Yamaguchi, Yasunaru Sakuma, Yoshinori Hosoya, Kotaro Yoshimura, Alan Lefor, Naohiro Sata, Joji Kitayama
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2258.
https://doi.org/10.1158/1538-7445.AM2020-2258
Published: 15 August 2020
View articletitled, Abstract 2258: CD73 targeting therapy enhances the anti-tumor effect of radiation therapy in rectal cancer
Journal Articles

Abstract 516: Metformin inhibits monocyte differentiation to tumor associated macrophage (TAM) and may restore anti-tumor immunity

Akira Saito, Hideyuki Ohzawa, Mineyuki Tojo, Yuko Kumagai, Rihito Kanamaru, Hidenori Tsukui, Satomi Shiba, Homare Ito, Naohiro Sata, Joji Kitayama
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 516.
https://doi.org/10.1158/1538-7445.AM2019-516
Published: 01 July 2019
View articletitled, Abstract 516: Metformin inhibits monocyte differentiation to tumor associated macrophage (TAM) and may restore anti-tumor immunity