1-18 of 18
John Wongvipat
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract NG06: CHD1-loss confers AR targeted therapy resistance via promoting cancer heterogeneity and lineage plasticity

Free
Zeda Zhang, Chuanli Zhou, Xiaoling Li, Spencer Barnes, Su Deng, Elizabeth Hoover, Chi-Chao Chen, Young Sun Lee, Choushi Wang, Carla Tirado, Lauren Metang, Nickolas Johnson, John Wongvipat, Kristina Navrazhina, Zhen Cao, Wassim Abida, Amaia Lujambio, Sheng Li, Vankat Malladi, Charles Sawyers, Ping Mu
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): NG06.
https://doi.org/10.1158/1538-7445.AM2020-NG06
Published: 15 August 2020
View articletitled, Abstract NG06: CHD1-loss confers AR targeted therapy resistance via promoting cancer heterogeneity and lineage plasticity
Journal Articles

Abstract 3430: The protein phosphatase 4 complex is a tumor suppressor in prostate cancer

Free
Philip A. Watson, Kayla E. Lawrence, Tejasveeta V. Nadkarni, Taslima F. Ishmael, Eugine Lee, Aura C. Agudelo Rivera, Jillian R. Love, John Wongvipat, Ling Cai, Abbas Nazir, Phillip J. Iaquinta, Kenneth Chang, Yupu Liang, Greg J. Hannon, Charles L. Sawyers
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3430.
https://doi.org/10.1158/1538-7445.AM2020-3430
Published: 15 August 2020
View articletitled, Abstract 3430: The protein phosphatase 4 complex is a tumor suppressor in prostate cancer
Journal Articles

Abstract A074: Aberrant activation of a gastrointestinal transcriptional circuit in prostate cancer mediates castration resistance

Free
Shipra Shukla, Joanna Cyrta, Devan Murphy, Edward Walczak, Leili Ran, Praveen Agrawal, Yuanyuan Xie, Yuedan Chen, Shangqian Wang, Yu Zhan, Wai Pung E. Wong, Andrea Sboner, Himisha Beltran, Juan-Miguel Mosquera, Jessica Sher, Zhen Cao, John Wongvipat, Richard P. Koche, Anuradha Gopalan, Deyou Zheng, Mark Rubin, Howard I. Scher, Ping Chi, Yu Chen
Journal: Cancer Research
Cancer Res (2018) 78 (16_Supplement): A074.
https://doi.org/10.1158/1538-7445.PRCA2017-A074
Published: 14 August 2018
View articletitled, Abstract A074: Aberrant activation of a gastrointestinal transcriptional circuit in prostate cancer mediates castration resistance
Journal Articles

Abstract 1537: 3p13-14 FOXP1-SHQ1 deletion spanning multiple potential tumor suppressor genes cooperates with PTEN loss in cancer

Free
Haley Hieronymus, Philip J. Iaquinta, John Wongvipat, Anuradha Gopalan, Rajmohan Murali, Ninghui Mao, Brett S. Carver, Charles L. Sawyers
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1537.
https://doi.org/10.1158/1538-7445.AM2017-1537
Published: 01 July 2017
View articletitled, Abstract 1537: 3p13-14 FOXP1-SHQ1 deletion spanning multiple potential tumor suppressor genes cooperates with PTEN loss in cancer
Journal Articles

Abstract 4165: SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 and RB1 deficient prostate cancer

Free
Ping Mu, Zeda Zhang, Matteo Benelli, Wouter Karthaus, Elizebeth Hoover, Chi-Chao Chen, John Wongvipat, Sheng-Yu Ku, Dong Gao, Zhen Cao, Neel Shah, Elizabeth Adams, Wassim Abida, Philip Watson, Davide Prandi, Chun-Hao Huang, Elisa de Stanchina, Scott Lowe, Leigh Ellis, Himisha Beltran, Mark Rubin, David Goodrich, Francesca Demichelis, Charles L. Sawyers
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4165.
https://doi.org/10.1158/1538-7445.AM2017-4165
Published: 01 July 2017
View articletitled, Abstract 4165: SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 and RB1 deficient prostate cancer
Journal Articles

Abstract 238: Androgen insensitivity syndrome germline loss-of-function mutations in the androgen receptor that acquire somatic gain-of-function in prostate cancer

Free
Philip A. Watson, Minna D. Balbas, Zeda Zhang, Taslima F. Ishmael, Kayla E. Lawrence, John Wongvipat, Sophie D. Sawyers, Yi-Mi Wu, Dan Robinson, Yang Shen, Arul M. Chinnaiyan, Charles L. Sawyers
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 238.
https://doi.org/10.1158/1538-7445.AM2016-238
Published: 15 July 2016
View articletitled, Abstract 238: Androgen insensitivity syndrome germline loss-of-function mutations in the androgen receptor that acquire somatic gain-of-function in prostate cancer
Journal Articles

Abstract 3098: Epigenetic therapy to target neuroendocrine prostate cancer using precision medicine models

Free
Loredana Puca, Wouter R. Karthaus, Dong Gao, John Wongvipat, Andrea Sboner, Marcello Gaudiano, Chantal Pauli, Rema A. Rao, Juan Miguel Mosquera, Joanna Cyrta, Theresa Y. MacDonald, Giorgio Ga Inghirami, Yu Chen, Mark A. Rubin, Himisha Beltran
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3098.
https://doi.org/10.1158/1538-7445.AM2016-3098
Published: 15 July 2016
View articletitled, Abstract 3098: Epigenetic therapy to target neuroendocrine prostate cancer using precision medicine models
Journal Articles

Abstract LB-018: Loss of function mutations of an ETS repressor expand the ETS positive subset of prostate cancer

Free
Rohit Bose, Wassim Abida, Wouter Karthaus, Joshua Armenia, Phillip Iaquinta, John Wongvipat, Michael Doran, Haley Hieronymus, Philip Watson, Patrick Sullivan, Yupu Liang, Nikolaus Schultz, Charles Sawyers
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-018.
https://doi.org/10.1158/1538-7445.AM2016-LB-018
Published: 15 July 2016
View articletitled, Abstract LB-018: Loss of function mutations of an ETS repressor expand the ETS positive subset of prostate cancer
Journal Articles

Androgen Receptor Upregulation Mediates Radioresistance after Ionizing Radiation

Free
Daniel E. Spratt, Michael J. Evans, Brian J. Davis, Michael G. Doran, Man Xia Lee, Neel Shah, John Wongvipat, Kathryn E. Carnazza, George G. Klee, William Polkinghorn, Donald J. Tindall, Jason S. Lewis, Charles L. Sawyers
Journal: Cancer Research
Cancer Res (2015) 75 (22): 4688–4696.
https://doi.org/10.1158/0008-5472.CAN-15-0892
Published: 15 November 2015
View articletitled, Androgen Receptor Upregulation Mediates Radioresistance after Ionizing Radiation
Open the PDF for Androgen Receptor Upregulation Mediates Radioresistance after Ionizing Radiation in another window
Includes: Supplementary data
Journal Articles

Abstract LB-056: TP53 and RB1 alterations promote reprogramming and antiandrogen resistance in advanced prostate cancer

Free
Ping Mu, Zhen Cao, Elizabeth Hoover, John Wongvipat, Chun-Hao Huang, Wouter Karthaus, Wassim Abida, Elisa De Stanchina, Charles Sawyers
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-056.
https://doi.org/10.1158/1538-7445.AM2015-LB-056
Published: 01 August 2015
View articletitled, Abstract LB-056: TP53 and RB1 alterations promote reprogramming and antiandrogen resistance in advanced prostate cancer
Journal Articles

Abstract 3396: Dual lineage inhibition of ETV1 and KIT disrupts the ETV1-KIT feed forward circuit and potentiates imatinib antitumor effect in GIST oncogenesis

Free
Leili Ran, Inna Sirota, Zhen Cao, Devan Murphy, Shipra Shukla, Ferdinando Rossi, John Wongvipat, William D. Tap, Peter Besmer, Cristina R. Antonescu, Yu Chen, Ping Chi
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3396.
https://doi.org/10.1158/1538-7445.AM2014-3396
Published: 01 October 2014
View articletitled, Abstract 3396: Dual lineage inhibition of ETV1 and KIT disrupts the ETV1-KIT feed forward circuit and potentiates imatinib antitumor effect in GIST oncogenesis
Journal Articles

Abstract 4774: The antitumor effects of PI3K beta inhibitors in PTEN negative prostate cancer are enhanced by inhibition of reactivated PI3K alpha signaling

Free
Sarit Schwartz, Brett S. Carver, John Wongvipat, Vanessa Rodrik-Outmezguine, Elisa D. Stanchina, Cath Trigwell, Simon Barry, Jose Baselga, Sarat Chandarlapaty, Howard I. Scher, Charles L. Sawyers, Neal Rosen
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4774.
https://doi.org/10.1158/1538-7445.AM2014-4774
Published: 01 October 2014
View articletitled, Abstract 4774: The antitumor effects of PI3K beta inhibitors in PTEN negative prostate cancer are enhanced by inhibition of reactivated PI3K alpha signaling
Journal Articles

Abstract PR3: The snoRNP assembly factor SHQ1 is a novel prostate cancer tumor suppressor gene

Free
Phillip J. Iaquinta, Chee Wai Chua, Rosario Machado-Pinilla, Haley Hieronymus, John Wongvipat, U. Thomas Meier, Michael Shen, Charles L. Sawyers
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): PR3.
https://doi.org/10.1158/1538-7445.PRCA2012-PR3
Published: 09 May 2013
View articletitled, Abstract PR3: The snoRNP assembly factor SHQ1 is a novel prostate cancer tumor suppressor gene
Journal Articles

ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment

Free
Nicola J. Clegg, John Wongvipat, James D. Joseph, Chris Tran, Samedy Ouk, Anna Dilhas, Yu Chen, Kate Grillot, Eric D. Bischoff, Ling Cai, Anna Aparicio, Steven Dorow, Vivek Arora, Gang Shao, Jing Qian, Hong Zhao, Guangbin Yang, Chunyan Cao, John Sensintaffar, Teresa Wasielewska, Mark R. Herbert, Celine Bonnefous, Beatrice Darimont, Howard I. Scher, Peter Smith-Jones, Mark Klang, Nicholas D. Smith, Elisa De Stanchina, Nian Wu, Ouathek Ouerfelli, Peter J. Rix, Richard A. Heyman, Michael E. Jung, Charles L. Sawyers, Jeffrey H. Hager
Journal: Cancer Research
Cancer Res (2012) 72 (6): 1494–1503.
https://doi.org/10.1158/0008-5472.CAN-11-3948
Published: 14 March 2012
View articletitled, ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment
Open the PDF for ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment in another window
Includes: Supplementary data
Journal Articles

Abstract #4924: Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis

Free
Jennifer King, Jin Xu, John Wongvipat, Haley Hieronymus, David Leung, Barry Taylor, Chris Sander, Robert Cardiff, Suzana Couto, William Gerald, Charles Sawyers
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4924.
Published: 01 May 2009
View articletitled, Abstract #4924: Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis
Journal Articles

Evidence for an androgen receptor threshold dependency in prostate cancer cells with natural androgen receptor overexpression.

Free
Philip Watson, John Wongvipat, David Leung, Charles Sawyers
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1581.
Published: 01 May 2008
View articletitled, Evidence for an androgen receptor threshold dependency in prostate cancer cells with natural androgen receptor overexpression.
Journal Articles

Transgenic Mouse Model for Rapid Pharmacodynamic Evaluation of Antiandrogens

Free
Katharine Ellwood-Yen, John Wongvipat, Charles Sawyers
Journal: Cancer Research
Cancer Res (2006) 66 (21): 10513–10516.
https://doi.org/10.1158/0008-5472.CAN-06-1397
Published: 01 November 2006
View articletitled, Transgenic Mouse Model for Rapid Pharmacodynamic Evaluation of Antiandrogens
Open the PDF for Transgenic Mouse Model for Rapid Pharmacodynamic Evaluation of Antiandrogens in another window
Journal Articles

Context-Dependent Hormone-Refractory Progression Revealed through Characterization of a Novel Murine Prostate Cancer Cell Line

Free
Philip A. Watson, Katharine Ellwood-Yen, Jennifer C. King, John Wongvipat, Michelle M. LeBeau, Charles L. Sawyers
Journal: Cancer Research
Cancer Res (2005) 65 (24): 11565–11571.
https://doi.org/10.1158/0008-5472.CAN-05-3441
Published: 15 December 2005
View articletitled, Context-Dependent Hormone-Refractory Progression Revealed through Characterization of a Novel Murine Prostate Cancer Cell Line
Open the PDF for Context-Dependent Hormone-Refractory Progression Revealed through Characterization of a Novel Murine Prostate Cancer Cell Line in another window