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John W. Marks
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Journal Articles

Abstract 860: In vitro and in vivo studies of a novel, functionalized, completely human serine protease targeting Her2/neu. Activity against Herceptin- and multi-drug resistant tumor cells .

Yu Cao, Khalid A. Mohamedali, John W. Marks, Lawrence H. Cheung, Walter N. Hittelman, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 860.
https://doi.org/10.1158/1538-7445.AM2013-860
Published: 15 April 2013
View articletitled, Abstract 860: In vitro and in vivo studies of a novel, functionalized, completely human serine protease targeting Her2/neu. Activity against Herceptin- and multi-drug resistant tumor cells .
Journal Articles

Abstract 3378: The rGel/BLyS fusion toxin can overcome chemoresistance in malignant B cells..

Mi-Ae Lyu, Lawrence H. Cheung, John W. Marks, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3378.
https://doi.org/10.1158/1538-7445.AM2013-3378
Published: 15 April 2013
View articletitled, Abstract 3378: The rGel/BLyS fusion toxin can overcome chemoresistance in malignant B cells..
Journal Articles

Abstract 3866: TWEAK receptor (Fn14) Is a novel target in melanoma: Characterization of unique targeted therapeutics

Hong Zhou, Suhendan Ekmekcioglu, John W. Marks, Kaushal Asrani, Keeley K. Phillips, Sharron Brown, Emily Cheng, Michele B. Weiss, Walter N. Hittelman, Nhan L. Tran, Hideo Yagita, Jeffrey A. Winkles, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3866.
https://doi.org/10.1158/1538-7445.AM2012-3866
Published: 15 April 2012
View articletitled, Abstract 3866: TWEAK receptor (Fn14) Is a novel target in melanoma: Characterization of unique targeted therapeutics
Journal Articles

Abstract 3865: The rGel/BLyS fusion toxin enhances the therapeutic effects of bortezomib in in vitro and in vivo models of mantle cell lymphoma.

Mi-Ae Lyu, Lan V. Pham, Bokyung Sung, Archito T. Tamayo, Kwang Seok Ahn, Lawrence H. Cheung, John W. Marks, Richard J. Ford, Bharat B. Aggarwal, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3865.
https://doi.org/10.1158/1538-7445.AM2012-3865
Published: 15 April 2012
View articletitled, Abstract 3865: The rGel/BLyS fusion toxin enhances the therapeutic effects of bortezomib in in vitro and in vivo models of mantle cell lymphoma.
Journal Articles

Abstract 2730: Anti-Her2/neu immunotoxins: Impact of monovalent and bivalent designs on in vitro and in vivo antitumor efficacy

Yu Cao, John W. Marks, Zhigang Liu, Lawrence H. Chueng, Walter N. Hittelman, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2730.
https://doi.org/10.1158/1538-7445.AM2012-2730
Published: 15 April 2012
View articletitled, Abstract 2730: Anti-Her2/neu immunotoxins: Impact of monovalent and bivalent designs on in vitro and in vivo antitumor efficacy
Journal Articles

Abstract 1759: Design optimization and characterization of novel herceptin-based immunotoxins for cancer therapy. Enhanced antitumor activity in vitro and in vivo

Yu Cao, John W. Marks, Sean Carroll, George Georgiou, Walter N. Hittelman, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1759.
https://doi.org/10.1158/1538-7445.AM2011-1759
Published: 15 April 2011
View articletitled, Abstract 1759: Design optimization and characterization of novel herceptin-based immunotoxins for cancer therapy. Enhanced antitumor activity in vitro and in vivo
Journal Articles

Abstract 1758: Influence of stromal microenvironment on rGel/BLyS-induced cytotoxicity in diffuse large B-cell lymphoma cells

Mi-Ae Lyu, Lawrence H. Cheung, John W. Marks, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1758.
https://doi.org/10.1158/1538-7445.AM2011-1758
Published: 15 April 2011
View articletitled, Abstract 1758: Influence of stromal microenvironment on rGel/BLyS-induced cytotoxicity in diffuse large B-cell lymphoma cells
Journal Articles

Abstract 1766: Development of single chain immunotoxins targeting the fibroblast growth factor-inducible 14 (Fn14) receptor on solid tumor cells

Hong Zhou, John W. Marks, Suhendan Ekmekcioglu, Walter N. Hittelman, Nhan Tran, Hideo Yagita, Jeffrey A. Winkles, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1766.
https://doi.org/10.1158/1538-7445.AM2011-1766
Published: 15 April 2011
View articletitled, Abstract 1766: Development of single chain immunotoxins targeting the fibroblast growth factor-inducible 14 (Fn14) receptor on solid tumor cells
Journal Articles

Abstract 4399: EphA2-targeting antibody-gelonin conjugate specifically binds and kills target-expressing tumor cells, including multi-drug resistant (MDR) lines

John W. Marks, John Gooya, Nabendu Pore, Shenlan Mao, Dowdy Jackson, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4399.
https://doi.org/10.1158/1538-7445.AM10-4399
Published: 15 April 2010
View articletitled, Abstract 4399: EphA2-targeting antibody-gelonin conjugate specifically binds and kills target-expressing tumor cells, including multi-drug resistant (MDR) lines
Journal Articles

Abstract 2579: Bax345/BLyS: A novel, completely human fusion construct targeting malignant B cells and delivering a unique mitochondrial toxin

Mi-Ae Lyu, Lawrence H. Cheung, John W. Marks, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2579.
https://doi.org/10.1158/1538-7445.AM10-2579
Published: 15 April 2010
View articletitled, Abstract 2579: Bax345/BLyS: A novel, completely human fusion construct targeting malignant B cells and delivering a unique mitochondrial toxin
Journal Articles

Abstract 2574: Development and characterization of a potent immunotoxin targeting the Fn14 receptor on solid tumor cells

Hong Zhou, John W. Marks, Jeffrey A. Winkles, Hideo Yagita, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2574.
https://doi.org/10.1158/1538-7445.AM10-2574
Published: 15 April 2010
View articletitled, Abstract 2574: Development and characterization of a potent immunotoxin targeting the Fn14 receptor on solid tumor cells
Journal Articles

Abstract 2576: Novel adnectin/rGelonin fusion constructs targeting the insulin-like growth factor(IGF1) receptor on tumor cells

Zhigang Liu, Weihe Zhang, Lee M. Ellis, Fan Fan, Yu Cao, Lawrence H. Cheung, John W. Marks, Hong Zhou, Raymond Camphausen, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2576.
https://doi.org/10.1158/1538-7445.AM10-2576
Published: 15 April 2010
View articletitled, Abstract 2576: Novel adnectin/rGelonin fusion constructs targeting the insulin-like growth factor(IGF1) receptor on tumor cells
Journal Articles

Construction and Characterization of Novel, Recombinant Immunotoxins Targeting the Her2/neu Oncogene Product: In vitro and In vivo Studies

Yu Cao, James D. Marks, John W. Marks, Lawrence H. Cheung, Sehoon Kim, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2009) 69 (23): 8987–8995.
https://doi.org/10.1158/0008-5472.CAN-09-2693
Published: 30 November 2009
View articletitled, Construction and Characterization of Novel, Recombinant Immunotoxins Targeting the Her2/neu Oncogene Product: In vitro and In vivo Studies
Open the PDF for Construction and Characterization of Novel, Recombinant Immunotoxins Targeting the Her2/neu Oncogene Product: In vitro and In vivo Studies in another window
Includes: Supplementary data
Journal Articles

Inhibition of leukemia growth by a recombinant gelonin conjugate of anti-FLT3 monoclonal antibody

Yiwen Li, Michael Rosenblum, Hongli Li, Rajiv Bassi, Wenzhi Tian, John W. Marks, Daniel Hicklin
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4114.
Published: 01 May 2007
View articletitled, Inhibition of leukemia growth by a recombinant gelonin conjugate of anti-FLT3 monoclonal antibody
Journal Articles

Aptamer:Toxin Conjugates that Specifically Target Prostate Tumor Cells

Ted C. Chu, John W. Marks, III, Laura A. Lavery, Sarah Faulkner, Michael G. Rosenblum, Andrew D. Ellington, Matthew Levy
Journal: Cancer Research
Cancer Res (2006) 66 (12): 5989–5992.
https://doi.org/10.1158/0008-5472.CAN-05-4583
Published: 15 June 2006
View articletitled, Aptamer:Toxin Conjugates that Specifically Target Prostate Tumor Cells
Open the PDF for Aptamer:Toxin Conjugates that Specifically Target Prostate Tumor Cells in another window
Includes: Supplementary data
Journal Articles

Characterization Studies of Recombinant Fusion Constructs Targeting FGFR3 and Containing Recombinant Gelonin (rGel)

Lawrence H. Cheung, Jorge L. Martinez-Torrecuadrada, John W. Marks, III, Michael G. Rosenblum, Ignacio Casal
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 465.
Published: 15 April 2006
View articletitled, Characterization Studies of Recombinant Fusion Constructs Targeting FGFR3 and Containing Recombinant Gelonin (rGel)
Journal Articles

The growth factor fusion toxin rGel/BLyS induces cell cycle arrest and apoptosis in mantle cell lymphoma lines

Mi-Ae Lyu, Kwang Seok Ahn, Lawrence H. Cheung, John W. Marks, III, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 876.
Published: 15 April 2006
View articletitled, The growth factor fusion toxin rGel/BLyS induces cell cycle arrest and apoptosis in mantle cell lymphoma lines
Journal Articles

Fullerene(C60)-immunoconjugates: Interaction of customized water-soluble C60 derivatives with the murine anti-gp240 melanoma antibody

Jared M. Ashcroft, Dmitry A. Tsyboulski, Sergey Bachilo, R. Bruce Weisman, John W. Marks, Michael G. Rosenblum, Lon J. Wilson
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 726.
Published: 15 April 2006
View articletitled, Fullerene(C60)-immunoconjugates: Interaction of customized water-soluble C60 derivatives with the murine anti-gp240 melanoma antibody
Journal Articles

The growth factor toxin construct rGel/BLyS specifically targets tumor cells expressing BAFF-R, TACI, and BCMA

Mi-Ae Lyu, Lawrence H. Cheung, John W. Marks, III, Walter N. Hittelman, Varsha V. Gandhi, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 355–356.
Published: 01 May 2005
View articletitled, The growth factor toxin construct rGel/BLyS specifically targets tumor cells expressing BAFF-R, TACI, and BCMA
Journal Articles

Targeting PSMA on tumor cells using novel aptamer-gelonin conjugates

Andrew D. Ellington, John W. Marks, III, Ted Chitai Chu, Laura Lavery, Sarah Faulkner, Matthew Levy, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1455.
Published: 01 May 2005
View articletitled, Targeting PSMA on tumor cells using novel aptamer-gelonin conjugates