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Journal Articles

Abstract 6616: Polygenic risk score associated with risk of upgrading and tumor features in a prospective cohort of prostate cancer patients on active surveillance

Louisa B. Goss, Menghan Liu, Yingye Zheng, Boya Guo, David V. Conti, Christopher A. Haiman, William J. Catalona, John S. Witte, Daniel W. Lin, Lisa F. Newcomb, Burcu F. Darst

Cancer Res (2024) 84 (6_Supplement): 6616.

https://doi.org/10.1158/1538-7445.AM2024-6616

Published: 22 March 2024

View articletitled, Abstract 6616: Polygenic risk score associated with risk of upgrading and tumor features in a prospective cohort of prostate cancer patients on active surveillance

Journal Articles

Abstract 1446: Genetic risk factors for the development of multiple primary cancers

Jovia L. Nierenberg, Linda Kachuri, Taylor B. Cavazos, Rebecca E. Graff, Thomas J. Hoffmann, Jie Zhang, Stacey Alexeeff, Laurel Habel, Douglas Corley, Stephen Van Den Eeden, Elad Ziv, Lori C. Sakoda, John S. Witte

Cancer Res (2022) 82 (12_Supplement): 1446.

https://doi.org/10.1158/1538-7445.AM2022-1446

Published: 15 June 2022

View articletitled, Abstract 1446: Genetic risk factors for the development of multiple primary cancers

Journal Articles

Abstract 1441: Genetic determinants of PSA levels improve prostate cancer screening

Linda Kachuri, Rebecca E. Graff, Sonja I. Berndt, Mitchell Machiela, Neal D. Freedman, Stephen J. Chanock, John P. Shelley, Kerry Schaffer, Jonathan D. Mosley, Phyllis J. Goodman, Cathee Till, Ian Thompson, Robert J. Klein, Stephen K. Van Den Eeden, Thomas J. Hoffmann, John S. Witte

Cancer Res (2022) 82 (12_Supplement): 1441.

https://doi.org/10.1158/1538-7445.AM2022-1441

Published: 15 June 2022

View articletitled, Abstract 1441: Genetic determinants of PSA levels improve prostate cancer screening

Journal Articles

Abstract LB011: Meta-analysis in more than 80,000 men of African ancestry identified nine novel variants associated with prostate cancer

Fei Chen, Ravi K. Madduri, Xin Sheng, Alex Rodriguez, Alisha Chou, Todd L. Edwards, Stephen K. Van Den Eeden, Rosalind A. Eeles, John S. Witte, Michael B. Cook, William J. Blot, David V. Conti, John M. Gaziano, Amy C. Justice, Christopher A. Haiman, VA Million Veteran Program and PRACTICAL/ELLIPSE Consortium

Cancer Res (2021) 81 (13_Supplement): LB011.

https://doi.org/10.1158/1538-7445.AM2021-LB011

Published: 01 July 2021

View articletitled, Abstract LB011: Meta-analysis in more than 80,000 men of African ancestry identified nine novel variants associated with prostate cancer

Journal Articles

Abstract NG03: Multiethnic prostate cancer GWAS meta-analysis identifies novel variants, improves genetic risk prediction across populations, and informs biological mechanisms of prostate cancer

Cancer Res (2021) 81 (13_Supplement): NG03.

https://doi.org/10.1158/1538-7445.AM2021-NG03

Published: 01 July 2021

View articletitled, Abstract NG03: Multiethnic prostate cancer GWAS meta-analysis identifies novel variants, improves genetic risk prediction across populations, and informs biological mechanisms of prostate cancer

Journal Articles

A Large-Scale Association Study Detects Novel Rare Variants, Risk Genes, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility

Cancer Res (2021) 81 (7): 1695–1703.

https://doi.org/10.1158/0008-5472.CAN-20-2635

Published: 01 April 2021

View articletitled, A Large-Scale Association Study Detects Novel Rare Variants, Risk Genes, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility

Includes: Supplementary data

Journal Articles

Abstract 719: Assessing the utility of cell-free DNA in identifying prostate cancer and characterizing tumor heterogeneity via targeted, whole exome, and whole genome multi-region sequencing

Cancer Res (2020) 80 (16_Supplement): 719.

https://doi.org/10.1158/1538-7445.AM2020-719

Published: 15 August 2020

View articletitled, Abstract 719: Assessing the utility of cell-free DNA in identifying prostate cancer and characterizing tumor heterogeneity via targeted, whole exome, and whole genome multi-region sequencing

Journal Articles

Abstract 2319: Pan-cancer analysis of polygenic risk scores reveals improvement in risk prediction and stratification

Linda Kachuri, Rebecca E. Graff, Karl Smith-Byrne, Travis J. Meyers, Sara R. Rashkin, Elad Ziv, John S. Witte, Mattias Johansson

Cancer Res (2020) 80 (16_Supplement): 2319.

https://doi.org/10.1158/1538-7445.AM2020-2319

Published: 15 August 2020

View articletitled, Abstract 2319: Pan-cancer analysis of polygenic risk scores reveals improvement in risk prediction and stratification

Journal Articles

Identification of Novel Susceptibility Loci and Genes for Prostate Cancer Risk: A Transcriptome-Wide Association Study in Over 140,000 European Descendants

Lang Wu, Jifeng Wang, Qiuyin Cai, Taylor B. Cavazos, Nima C. Emami, Jirong Long, Xiao-Ou Shu, Yingchang Lu, Xingyi Guo, Joshua A. Bauer, Bogdan Pasaniuc, Kathryn L. Penney, Matthew L. Freedman, Zsofia Kote-Jarai, John S. Witte, Christopher A. Haiman, Rosalind A. Eeles, Wei Zheng

Cancer Res (2019) 79 (13): 3192–3204.

https://doi.org/10.1158/0008-5472.CAN-18-3536

Published: 01 July 2019

View articletitled, Identification of Novel Susceptibility Loci and Genes for Prostate Cancer Risk: A Transcriptome-Wide Association Study in Over 140,000 European Descendants

Includes: Supplementary data

Journal Articles

Abstract 3669: Assessing the genetic heterogeneity of localized, multifocal prostate cancer via cell-free DNA

Emmalyn Chen, Clinton L. Cario, Lancelote Leong, Karen Lopez, Jeffry P. Simko, Peter R. Carroll, Caroline Tai, John S. Witte

Cancer Res (2018) 78 (13_Supplement): 3669.

https://doi.org/10.1158/1538-7445.AM2018-3669

Published: 01 July 2018

View articletitled, Abstract 3669: Assessing the genetic heterogeneity of localized, multifocal prostate cancer via cell-free DNA

Journal Articles

Abstract 2968: Imputation of the prostate cancer transcriptome in over 230,000 men reveals novel germline-somatic interaction mechanism of cancer risk

Nima C. Emami, Joshua Hoffman, Elad Ziv, John S. Witte

Cancer Res (2018) 78 (13_Supplement): 2968.

https://doi.org/10.1158/1538-7445.AM2018-2968

Published: 01 July 2018

View articletitled, Abstract 2968: Imputation of the prostate cancer transcriptome in over 230,000 men reveals novel germline-somatic interaction mechanism of cancer risk

Journal Articles

Abstract 1297: Genetic reclassification of prostate-specific antigen levels for personalized prostate cancer screening

Cancer Res (2017) 77 (13_Supplement): 1297.

https://doi.org/10.1158/1538-7445.AM2017-1297

Published: 01 July 2017

View articletitled, Abstract 1297: Genetic reclassification of prostate-specific antigen levels for personalized prostate cancer screening

Journal Articles

Abstract 1316: Germline genetic signals across multiple aggressive prostate cancer phenotypes

Caroline G. Tai, Nima C. Emami, Thomas J. Hoffmann, Lori C. Sakoda, Eric Jorgenson, Laurel A. Habel, Jun Shan, Dilrini K. Ranatunga, Chun R. Chao, Nirupa R. Ghai, David Aaronson, Joseph Presti, Catherine Schaefer, Neil Risch, Stephen K. Van Den Eeden, John S. Witte

Cancer Res (2017) 77 (13_Supplement): 1316.

https://doi.org/10.1158/1538-7445.AM2017-1316

Published: 01 July 2017

View articletitled, Abstract 1316: Germline genetic signals across multiple aggressive prostate cancer phenotypes

Journal Articles

Abstract 1310: Identification of pleiotropic cancer susceptibility variants from genome-wide association studies reveals functional characteristics

Yi-Hsuan Wu, Rebecca E. Graff, Michael N. Passarelli, Thomas J. Hoffmann, Elad Ziv, John S. Witte

Cancer Res (2017) 77 (13_Supplement): 1310.

https://doi.org/10.1158/1538-7445.AM2017-1310

Published: 01 July 2017

View articletitled, Abstract 1310: Identification of pleiotropic cancer susceptibility variants from genome-wide association studies reveals functional characteristics

Journal Articles

Mutational Landscape of Aggressive Prostate Tumors in African American Men

Karla J. Lindquist, Pamela L. Paris, Thomas J. Hoffmann, Niall J. Cardin, Rémi Kazma, Joel A. Mefford, Jeffrey P. Simko, Vy Ngo, Yalei Chen, Albert M. Levin, Dhananjay Chitale, Brian T. Helfand, William J. Catalona, Benjamin A. Rybicki, John S. Witte

Cancer Res (2016) 76 (7): 1860–1868.

https://doi.org/10.1158/0008-5472.CAN-15-1787

Published: 31 March 2016

View articletitled, Mutational Landscape of Aggressive Prostate Tumors in African American Men

Includes: Supplementary data

Journal Articles

Abstract 4609: Risk loci in telomere structure and maintenance genes across five cancer types: GAME-ON Consortium

Cancer Res (2015) 75 (15_Supplement): 4609.

https://doi.org/10.1158/1538-7445.AM2015-4609

Published: 01 August 2015

View articletitled, Abstract 4609: Risk loci in telomere structure and maintenance genes across five cancer types: GAME-ON Consortium

Journal Articles

Abstract 5066: Generalizability of established prostate cancer risk variants in men of African ancestry

Cancer Res (2014) 74 (19_Supplement): 5066.

https://doi.org/10.1158/1538-7445.AM2014-5066

Published: 01 October 2014

View articletitled, Abstract 5066: Generalizability of established prostate cancer risk variants in men of African ancestry

Journal Articles

National Cancer Institute Prostate Cancer Genetics Workshop

William J. Catalona, Joan E. Bailey-Wilson, Nicola J. Camp, Stephen J. Chanock, Kathleen A. Cooney, Douglas F. Easton, Rosalind A. Eeles, Liesel M. FitzGerald, Matthew L. Freedman, Julius Gudmundsson, Rick A. Kittles, Elliott H. Margulies, Barry B. McGuire, Elaine A. Ostrander, Timothy R. Rebbeck, Janet L. Stanford, Stephen N. Thibodeau, John S. Witte, William B. Isaacs

Cancer Res (2011) 71 (10): 3442–3446.

https://doi.org/10.1158/0008-5472.CAN-11-0314

Published: 15 May 2011

View articletitled, National Cancer Institute Prostate Cancer Genetics Workshop

Journal Articles

Abstract 1895: Genetic polymorphisms of an innate immune gene, Toll-Like Receptor 4, and aggressive prostate cancer risk: A systematic review and meta-analysis

Yi-Ling Huang, John H. Page, Jen-Hau Chen, Yen-Ling Lin, Jianfeng Xu, Stella Koutros, Sonja Berndt, Stephen J. Chanock, John S. Witte, Yen-Ching Chen

Cancer Res (2011) 71 (8_Supplement): 1895.

https://doi.org/10.1158/1538-7445.AM2011-1895

Published: 15 April 2011

View articletitled, Abstract 1895: Genetic polymorphisms of an innate immune gene, Toll-Like Receptor 4, and aggressive prostate cancer risk: A systematic review and meta-analysis

Journal Articles

Abstract 938: Inflammation and immune response pathway analysis of lung cancer using hierarchal modeling based on GWAS data

Darren Brenner, Paul Brennan, Paolo Boffetta, Chris Amos, Margaret Spitz, Chu Chen, Gary Goodman, Erich Wichmann, Heike Bickeboller, Angela Risch, Simone Benhamou, Pierre Hainault, Gary Chen, John S. Witte, Rayjean J. Hung

Cancer Res (2010) 70 (8_Supplement): 938.

https://doi.org/10.1158/1538-7445.AM10-938

Published: 15 April 2010

View articletitled, Abstract 938: Inflammation and immune response pathway analysis of lung cancer using hierarchal modeling based on GWAS data

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Abstract 6616: Polygenic risk score associated with risk of upgrading and tumor features in a prospective cohort of prostate cancer patients on active surveillance

Abstract 1446: Genetic risk factors for the development of multiple primary cancers

Abstract 1441: Genetic determinants of PSA levels improve prostate cancer screening

Abstract LB011: Meta-analysis in more than 80,000 men of African ancestry identified nine novel variants associated with prostate cancer

Abstract NG03: Multiethnic prostate cancer GWAS meta-analysis identifies novel variants, improves genetic risk prediction across populations, and informs biological mechanisms of prostate cancer

A Large-Scale Association Study Detects Novel Rare Variants, Risk Genes, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility

Abstract 719: Assessing the utility of cell-free DNA in identifying prostate cancer and characterizing tumor heterogeneity via targeted, whole exome, and whole genome multi-region sequencing

Abstract 2319: Pan-cancer analysis of polygenic risk scores reveals improvement in risk prediction and stratification

Identification of Novel Susceptibility Loci and Genes for Prostate Cancer Risk: A Transcriptome-Wide Association Study in Over 140,000 European Descendants

Abstract 3669: Assessing the genetic heterogeneity of localized, multifocal prostate cancer via cell-free DNA

Abstract 2968: Imputation of the prostate cancer transcriptome in over 230,000 men reveals novel germline-somatic interaction mechanism of cancer risk

Abstract 1297: Genetic reclassification of prostate-specific antigen levels for personalized prostate cancer screening

Abstract 1316: Germline genetic signals across multiple aggressive prostate cancer phenotypes

Abstract 1310: Identification of pleiotropic cancer susceptibility variants from genome-wide association studies reveals functional characteristics

Mutational Landscape of Aggressive Prostate Tumors in African American Men

Abstract 4609: Risk loci in telomere structure and maintenance genes across five cancer types: GAME-ON Consortium

Abstract 5066: Generalizability of established prostate cancer risk variants in men of African ancestry

National Cancer Institute Prostate Cancer Genetics Workshop

Abstract 1895: Genetic polymorphisms of an innate immune gene, Toll-Like Receptor 4, and aggressive prostate cancer risk: A systematic review and meta-analysis

Abstract 938: Inflammation and immune response pathway analysis of lung cancer using hierarchal modeling based on GWAS data

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