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Journal Articles

Abstract 5500: A PTP4A3 inhibitor reduces ovarian cancer dissemination and alters STAT3 and ERK activation

John S. Lazo, Kelly N. Isbell, Danielle C. Llaneza, Ettore J. Rastelli, Charles N. Landen, Peter Wipf, Elizabeth R. Sharlow

Cancer Res (2022) 82 (12_Supplement): 5500.

https://doi.org/10.1158/1538-7445.AM2022-5500

Published: 15 June 2022

View article titled, Abstract 5500: A PTP4A3 inhibitor reduces ovarian cancer dissemination and alters STAT3 and ERK activation

Journal Articles

Abstract 1460: The design and biological characterization of PTP4A-targeted chemodegraders

Duncan J. Hart, Ettore J. Rastelli, Anna J. Mendelson, Christopher T. Letai, John Robert Cornelison, Elizabeth R. Sharlow, Peter Wipf, John S. Lazo

Cancer Res (2021) 81 (13_Supplement): 1460.

https://doi.org/10.1158/1538-7445.AM2021-1460

Published: 01 July 2021

View article titled, Abstract 1460: The design and biological characterization of PTP4A-targeted chemodegraders

Journal Articles

Abstract 1459: PTP4A3 phosphatase is a novel drug target for epithelial ovarian cancer

John Robert Cornelison, Ettore J. Rastelli, Duncan J. Hart, Anna J. Mendelson, Elizabeth R. Sharlow, Peter Wipf, John S. Lazo

Cancer Res (2021) 81 (13_Supplement): 1459.

https://doi.org/10.1158/1538-7445.AM2021-1459

Published: 01 July 2021

View article titled, Abstract 1459: PTP4A3 phosphatase is a novel drug target for epithelial ovarian cancer

Journal Articles

Abstract 2365: A chemical genetics approach identifies PTP4A3 as a regulator of colon cancer cell adhesion

Kelley E. McQueeney, Joseph M. Salamoun, Jennifer Ahn, Paula Pekic, Isabella K. Blanco, Heather Struckman, Elizabeth R. Sharlow, Peter Wipf, John S. Lazo

Cancer Res (2018) 78 (13_Supplement): 2365.

https://doi.org/10.1158/1538-7445.AM2018-2365

Published: 01 July 2018

View article titled, Abstract 2365: A chemical genetics approach identifies PTP4A3 as a regulator of colon cancer cell adhesion

Journal Articles

Abstract 3210: Targeting PTP4A3 phosphatase in ovarian cancer with the potent noncompetitive inhibitor JMS-631-053

John S. Lazo, Paula Pekic, Alex Cheung, Kelley McQueeney, Joseph Salamoun, Peter Wipf, Charles N. Landen, Elizabeth R. Sharlow

Cancer Res (2017) 77 (13_Supplement): 3210.

https://doi.org/10.1158/1538-7445.AM2017-3210

Published: 01 July 2017

View article titled, Abstract 3210: Targeting PTP4A3 phosphatase in ovarian cancer with the potent noncompetitive inhibitor JMS-631-053

Journal Articles

Abstract 1220: Coordinated chemical-genetics approach identifies PTP4A3-mediated regulation of colon cancer cell migration and extracellular matrix interactions

Kelley E. McQueeney, Joseph M. Salamoun, Isabella K. Blanco, Paula Pekic, Jennifer Ahn, Elizabeth R. Sharlow, Peter Wipf, John S. Lazo

Cancer Res (2017) 77 (13_Supplement): 1220.

https://doi.org/10.1158/1538-7445.AM2017-1220

Published: 01 July 2017

View article titled, Abstract 1220: Coordinated chemical-genetics approach identifies PTP4A3-mediated regulation of colon cancer cell migration and extracellular matrix interactions

Journal Articles

Abstract 202: Depletion of PTP4A3 phosphatase disrupts colorectal cancer cell adhesion and extracellular matrix interactions

Kelley E. McQueeney, Paula Pekic, Joseph M. Salamoun, Jennifer Ahn, Elizabeth R. Sharlow, Peter Wipf, John S. Lazo

Cancer Res (2016) 76 (14_Supplement): 202.

https://doi.org/10.1158/1538-7445.AM2016-202

Published: 15 July 2016

View article titled, Abstract 202: Depletion of PTP4A3 phosphatase disrupts colorectal cancer cell adhesion and extracellular matrix interactions

Journal Articles

Abstract 3258: Targeted-deletion of Ptp4a3 suppresses murine colon tumorigenesis

Mark W. Zimmerman, Gregg E. Homanics, John S. Lazo

Cancer Res (2012) 72 (8_Supplement): 3258.

https://doi.org/10.1158/1538-7445.AM2012-3258

Published: 15 April 2012

View article titled, Abstract 3258: Targeted-deletion of Ptp4a3 suppresses murine colon tumorigenesis

Journal Articles

Abstract 2532: In vitro cytotoxicity, and pharmacokinetics, tissue distribution, and metabolism of the protein kinase D inhibitors, kb-NB142-70 and kb-NB184-43, in mice bearing human cancer xenografts

Guo Jianxia, Robert A. Parise, Jan H. Beumer, Dana M. Clausen, Merrill J. Egorin, John S. Lazo, Peter Wipf, Q. Jane Wang, Julie L. Eiseman

Cancer Res (2010) 70 (8_Supplement): 2532.

https://doi.org/10.1158/1538-7445.AM10-2532

Published: 15 April 2010

View article titled, Abstract 2532: <em>In vitro</em> cytotoxicity, and pharmacokinetics, tissue distribution, and metabolism of the protein kinase D inhibitors, kb-NB142-70 and kb-NB184-43, in mice bearing human cancer xenografts

Journal Articles

Abstract 2540: Cytotoxicity, pharmacokinetics and metabolism of 10074-G5, a novel small-molecule inhibitor of c-Myc

Dana Clausen, Jianxia Guo, Jan H. Beumer, Robert A. Parise, Lihua Bai, Merrill J. Egorin, John S. Lazo, Edward V. Prochownik, Julie L. Eiseman

Cancer Res (2010) 70 (8_Supplement): 2540.

https://doi.org/10.1158/1538-7445.AM10-2540

Published: 15 April 2010

View article titled, Abstract 2540: Cytotoxicity, pharmacokinetics and metabolism of 10074-G5, a novel small-molecule inhibitor of c-Myc

Journal Articles

Abstract 5210: PRL-1 promotes cell metastatic processes and regulates filamentous actin dynamics

Masanao Nakashima, John S. Lazo

Cancer Res (2010) 70 (8_Supplement): 5210.

https://doi.org/10.1158/1538-7445.AM10-5210

Published: 15 April 2010

View article titled, Abstract 5210: PRL-1 promotes cell metastatic processes and regulates filamentous actin dynamics

Journal Articles

Abstract 5495: Identification of chemosensitivity nodes and small molecule inhibitors for breast cancer stem cell proliferation and survival

Fang Zhang, Kristi Rothermund, Edward V. Prochownik, John S. Lazo

Cancer Res (2010) 70 (8_Supplement): 5495.

https://doi.org/10.1158/1538-7445.AM10-5495

Published: 15 April 2010

View article titled, Abstract 5495: Identification of chemosensitivity nodes and small molecule inhibitors for breast cancer stem cell proliferation and survival

Journal Articles

microRNA-21 Negatively Regulates Cdc25A and Cell Cycle Progression in Colon Cancer Cells

Peng Wang, Fangdong Zou, Xiaodong Zhang, Hua Li, Austin Dulak, Robert J. Tomko, Jr., John S. Lazo, Zhenghe Wang, Lin Zhang, Jian Yu

Cancer Res (2009) 69 (20): 8157–8165.

https://doi.org/10.1158/0008-5472.CAN-09-1996

Published: 14 October 2009

View article titled, microRNA-21 Negatively Regulates Cdc25A and Cell Cycle Progression in Colon Cancer Cells

Includes: Supplementary data

Journal Articles

Multimodal Control of Cdc25A by Nitrosative Stress

Robert J. Tomko, Jr., John S. Lazo

Cancer Res (2008) 68 (18): 7457–7465.

https://doi.org/10.1158/0008-5472.CAN-08-0625

Published: 14 September 2008

View article titled, Multimodal Control of Cdc25A by Nitrosative Stress

Includes: Supplementary data

Journal Articles

Cell Division Cycle 25B Phosphatase Is Essential for Benzo(a)Pyrene-7,8-Diol-9,10-Epoxide–Induced Neoplastic Transformation

Sanjay K. Srivastava, Pallavi Bansal, Tetsuya Oguri, John S. Lazo, Shivendra V. Singh

Cancer Res (2007) 67 (19): 9150–9157.

https://doi.org/10.1158/0008-5472.CAN-07-0025

Published: 01 October 2007

View article titled, Cell Division Cycle 25B Phosphatase Is Essential for Benzo(<em>a</em>)Pyrene-7,8-Diol-9,10-Epoxide–Induced Neoplastic Transformation

Includes: Supplementary data

Journal Articles

Induction of Cdc25B Regulates Cell Cycle Resumption after Genotoxic Stress

Pallavi Bansal, John S. Lazo

Cancer Res (2007) 67 (7): 3356–3363.

https://doi.org/10.1158/0008-5472.CAN-06-3685

Published: 04 April 2007

View article titled, Induction of Cdc25B Regulates Cell Cycle Resumption after Genotoxic Stress

Includes: Supplementary data

Journal Articles

PRL-1 Tyrosine Phosphatase Regulates c-Src Levels, Adherence, and Invasion in Human Lung Cancer Cells

Hiroyuki Achiwa, John S. Lazo

Cancer Res (2007) 67 (2): 643–650.

https://doi.org/10.1158/0008-5472.CAN-06-2436

Published: 18 January 2007

View article titled, PRL-1 Tyrosine Phosphatase Regulates c-Src Levels, Adherence, and Invasion in Human Lung Cancer Cells

Journal Articles

Nitric oxide regulates Cdc25A phosphatase expression

Robert J. Tomko, Jr., John S. Lazo

Cancer Res (2006) 66 (8_Supplement): 1153.

Published: 15 April 2006

View article titled, Nitric oxide regulates Cdc25A phosphatase expression

Journal Articles

Involvement of PRL-1 in human lung cancer cell invasion and proliferation

Hiroyuki Achiwa, John S. Lazo

Cancer Res (2006) 66 (8_Supplement): 624.

Published: 15 April 2006

View article titled, Involvement of PRL-1 in human lung cancer cell invasion and proliferation

Journal Articles

DNA damaging agents rapidly induce the cell cycle checkpoint regulator Cdc25B

Pallavi Bansal, John S. Lazo

Cancer Res (2006) 66 (8_Supplement): 491.

Published: 15 April 2006

View article titled, DNA damaging agents rapidly induce the cell cycle checkpoint regulator Cdc25B

NARROW

Abstract 5500: A PTP4A3 inhibitor reduces ovarian cancer dissemination and alters STAT3 and ERK activation

Abstract 1460: The design and biological characterization of PTP4A-targeted chemodegraders

Abstract 1459: PTP4A3 phosphatase is a novel drug target for epithelial ovarian cancer

Abstract 2365: A chemical genetics approach identifies PTP4A3 as a regulator of colon cancer cell adhesion

Abstract 3210: Targeting PTP4A3 phosphatase in ovarian cancer with the potent noncompetitive inhibitor JMS-631-053

Abstract 1220: Coordinated chemical-genetics approach identifies PTP4A3-mediated regulation of colon cancer cell migration and extracellular matrix interactions

Abstract 202: Depletion of PTP4A3 phosphatase disrupts colorectal cancer cell adhesion and extracellular matrix interactions

Abstract 3258: Targeted-deletion of Ptp4a3 suppresses murine colon tumorigenesis

Abstract 2532: In vitro cytotoxicity, and pharmacokinetics, tissue distribution, and metabolism of the protein kinase D inhibitors, kb-NB142-70 and kb-NB184-43, in mice bearing human cancer xenografts

Abstract 2540: Cytotoxicity, pharmacokinetics and metabolism of 10074-G5, a novel small-molecule inhibitor of c-Myc

Abstract 5210: PRL-1 promotes cell metastatic processes and regulates filamentous actin dynamics

Abstract 5495: Identification of chemosensitivity nodes and small molecule inhibitors for breast cancer stem cell proliferation and survival

microRNA-21 Negatively Regulates Cdc25A and Cell Cycle Progression in Colon Cancer Cells

Multimodal Control of Cdc25A by Nitrosative Stress

Cell Division Cycle 25B Phosphatase Is Essential for Benzo(a)Pyrene-7,8-Diol-9,10-Epoxide–Induced Neoplastic Transformation

Induction of Cdc25B Regulates Cell Cycle Resumption after Genotoxic Stress

PRL-1 Tyrosine Phosphatase Regulates c-Src Levels, Adherence, and Invasion in Human Lung Cancer Cells

Nitric oxide regulates Cdc25A phosphatase expression

Involvement of PRL-1 in human lung cancer cell invasion and proliferation

DNA damaging agents rapidly induce the cell cycle checkpoint regulator Cdc25B

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