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John Monahan
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Journal Articles

Abstract 2929: The Mdm2 inhibitor NVP-CGM097 enhances the anti-tumor activity of NVP-LDK378 in ALK mutant neuroblastoma models

Hui Qin Wang, Linda Battalagine, Jinsheng Liang, Ensar Halilovic, Robert Schlegel, Alan Huang, Z. Alexander Cao, John Monahan, Fang Li
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2929.
https://doi.org/10.1158/1538-7445.AM2014-2929
Published: 01 October 2014
View article titled, Abstract 2929: The Mdm2 inhibitor NVP-CGM097 enhances the anti-tumor activity of NVP-LDK378 in ALK mutant neuroblastoma models
Journal Articles

Abstract 854: Patient stratification strategies for NVP-BGJ398, a selective pan-FGFR inhibitor in phase I clinical trials

Diana Graus Porta, Vito Guagnano, Christelle Stamm, Simon Woehrle, Audrey Kauffmann, Yao Yao, Thomas Brümmendorf, Vincent Bordas, Mickaël Le Douget, Yun Zhang, Zhi Chen, Moriko Ito, Fang Li, John Monahan, Alex Gaither, Jason Borawski, Christopher J. Wilson, Kavitha Venkatesan, Francesco Hofmann, William Sellers
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 854.
https://doi.org/10.1158/1538-7445.AM2012-854
Published: 15 April 2012
View article titled, Abstract 854: Patient stratification strategies for NVP-BGJ398, a selective pan-FGFR inhibitor in phase I clinical trials
Journal Articles

Abstract 2239: The effect combining the KIT inhibitor Imatinib with the PI3K inhibitor BKM120 or the dual PI3K/mTOR inhibitor BEZ235 on the proliferation of gastrointestinal stromal tumor cell lines

Fang Li, Joseph Growney, Linda Battalagine, Shumei Qiu, Paul Manley, John Monahan
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2239.
https://doi.org/10.1158/1538-7445.AM2012-2239
Published: 15 April 2012
View article titled, Abstract 2239: The effect combining the KIT inhibitor Imatinib with the PI3K inhibitor BKM120 or the dual PI3K/mTOR inhibitor BEZ235 on the proliferation of gastrointestinal stromal tumor cell lines
Journal Articles

Abstract 4738: Cellular resistance screening with a novel selective c-Met inhibitor reveals a spectrum of missense mutations that partially overlap with activating mutations found in cancer patients

Ralph Tiedt, Elisa Degenkolbe, Pascal Furet, Brent A. Appleton, Joseph Schoepfer, David Ruddy, John Monahan, Michael D. Jones, Jutta Blank, Dorothea Haasen, Peter Drueckes, Markus Wartmann, Clive McCarthy, Francesco Hofmann
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4738.
https://doi.org/10.1158/1538-7445.AM2011-4738
Published: 15 April 2011
View article titled, Abstract 4738: Cellular resistance screening with a novel selective c-Met inhibitor reveals a spectrum of missense mutations that partially overlap with activating mutations found in cancer patients
Journal Articles

Abstract 5455: Integrative analysis of the Cancer Cell Line Encyclopedia reveals genetic and transcriptional predictors of compound sensitivity

Jordi Barretina, Nicolas Stransky, Giordano Caponigro, Sungjoon Kim, Adam Margolin, Kavitha Venkhatesan, Gregory Kryukov, Michael Berger, John Monahan, Paula Morais, Jodi Meltzer, Scott Mahan, Dmitriy Sonkin, Pichai Raman, Michael Jones, Vic Meyer, Christopher Wilson, Joseph Thibault, Lauren Murray, Adam Callahan, John Che, Aaron Shipway, Nanxin Li, Ingo Engels, Andrew Su, Reid Pinchback, Jared Nedzel, Ted Liefeld, Lili Niu, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Robert Onofrio, Carrie Sougnez, Laura MacConaill, Wendy Winckler, Michael Reich, Jill Mesirov, Kristin Ardlie, Gad Getz, Michael Morrissey, Markus Warmuth, Matthew Meyerson, Peter Finan, Todd Golub, Barbara Weber, Jennifer Harris, William Sellers, Robert Schlegel, Levi Garraway
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5455.
https://doi.org/10.1158/1538-7445.AM2011-5455
Published: 15 April 2011
View article titled, Abstract 5455: Integrative analysis of the Cancer Cell Line Encyclopedia reveals genetic and transcriptional predictors of compound sensitivity
Journal Articles

Abstract 923: Separating the wheat from the chaff: A first look at the Cancer Cell Lines Encyclopedia sequencing data

Gregory V. Kryukov, Michael F. Berger, Nicolas Stransky, Jordi Barretina, Robert Onofrio, Giordano Caponigro, Carrie Sougnez, John Monahan, Erica Shefler, Kavitha Venkhatesan, Kristian Cibulskis, Paula Morais, Andrey Sivachenko, Jodi Meltzer, Michael Lawrence, Alex Ramos, Gad Getz, Broad's Genome Sequencing Platform, Joseph Thibault, Scott Mahan, Michael Jones, Michael Morrissey, Dmitry Sonkin, Kristin G. Ardlie, Todd Golub, Barbara Weber, Markus Warmuth, William Sellers, Jennifer Harris, Robert Schlegel, Levi A. Garraway
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 923.
https://doi.org/10.1158/1538-7445.AM2011-923
Published: 15 April 2011
View article titled, Abstract 923: Separating the wheat from the chaff: A first look at the Cancer Cell Lines Encyclopedia sequencing data
Journal Articles

The Polycomb Group Protein Bmi-1 Is Essential for the Growth of Multiple Myeloma Cells

Zainab Jagani, Dmitri Wiederschain, Alice Loo, Dan He, Rebecca Mosher, Paul Fordjour, John Monahan, Michael Morrissey, Yung-Mae Yao, Christoph Lengauer, Markus Warmuth, William R. Sellers, Marion Dorsch
Journal: Cancer Research
Cancer Res (2010) 70 (13): 5528–5538.
https://doi.org/10.1158/0008-5472.CAN-09-4229
Published: 30 June 2010
View article titled, The Polycomb Group Protein Bmi-1 Is Essential for the Growth of Multiple Myeloma Cells
Open the PDF for The Polycomb Group Protein Bmi-1 Is Essential for the Growth of Multiple Myeloma Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 138: Therapeutic targeting of inhibitor of apoptosis proteins

Leigh S. Zawel, Christopher Straub, Brant Firestone, John Sullivan, Kymberly Levine, Dale Porter, Colleen Conway, Guizhi Yang, Hui Gao, Dan He, Joanna Slisz, Michael Morrissey, John Monahan, Rebecca Mosher, Frank Stegmeier, Feng He, Ly Pham, Fan Yang, Julian Chen, Tim Ramsey, Megan Yao, Stephen Fawell
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 138.
https://doi.org/10.1158/1538-7445.AM10-138
Published: 15 April 2010
View article titled, Abstract 138: Therapeutic targeting of inhibitor of apoptosis proteins
Journal Articles

Abstract 2620: The Cancer Cell Line Encyclopedia project: From integrative cancer genomics to personalized cancer therapy

Jordi Barretina, Giordano Caponigro, Sungjoon Kim, Nicolas Stransky, Kavitha Venkhatesan, Venkateshwar Reddy, Michael Berger, Michael Morrissey, Paula Morais, Jodi Meltzer, Joseph Thibault, Scott Mahan, Dmitriy Sonkin, John Che, Pichai Raman, Jessica Slind, Cory Johannessen, Supriya Gupta, Lili Niu, Sarah Kehoe, Charlie Hatton, Mike Jones, John Monahan, Vic Meyer, Chris Wilson, Aaron Shipway, Nanxin Li, Ingo Engels, Andrew Su, Adam Callahan, Yan Ding, Ted Liefeld, Liuda Ziaugra, Carrie Sougnez, Robert Onofrio, Wendy Winckler, Laura MacConaill, Michael Reich, Stacey Gabriel, Kristin Ardlie, Gad Getz, Markus Warmuth, Matthew Meyerson, Peter Finan, Todd Golub, Barbara Weber, Jennifer Harris, William Sellers, Robert Schlegel, Levi Garraway
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2620.
https://doi.org/10.1158/1538-7445.AM10-2620
Published: 15 April 2010
View article titled, Abstract 2620: The Cancer Cell Line Encyclopedia project: From integrative cancer genomics to personalized cancer therapy
Journal Articles

Abstract 4290: The smoothened antagonist NVP-LDE225 targets stroma and cancer stem cells in primary human pancreatic tumor xenografts

Silvia Buonamici, Beatriz E. Ospina, Julia Xing Zhu, Jing Yuan, Kathy Hsiao, Anthony Vattay, Fang Li, James Deeds, Lance Ostrom, John Monahan, Juliet Williams, Joseph Kelleher, Stefan Peukert, Shifeng Pan, Xu Wu, Markus Warmuth, Rebecca Mosher, Yung-mae Yao, William R. Sellers, Marion Dorsch
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4290.
https://doi.org/10.1158/1538-7445.AM10-4290
Published: 15 April 2010
View article titled, Abstract 4290: The smoothened antagonist NVP-LDE225 targets stroma and cancer stem cells in primary human pancreatic tumor xenografts
Journal Articles

Abstract 1976: The discovery of mechanisms of resistance to SMO antagonists and the therapeutic implications

Marion Dorsch, Silvia Buonamici, Juliet Williams, Anlai Wang, Ribo Guo, Anthony Vattay, Kathy Hsiao, Jing Yuan, Lance Ostrom, Paul Fordjour, Dustin Anderson, Michael Morrissey, John Monahan, Joseph Kelleher, Stefan Peukert, Shifeng Pan, Xu Wu, Sauver-Michel Maira, Carlos Garcia-Echeverria, Kimberly Briggs, Neil Watkins, Yung-mae Yao, Christoph Lengauer, Markus Warmuth, William Sellers
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1976.
https://doi.org/10.1158/1538-7445.AM10-1976
Published: 15 April 2010
View article titled, Abstract 1976: The discovery of mechanisms of resistance to SMO antagonists and the therapeutic implications
Journal Articles

Highly sensitive somatic mutation detection in tumor samples by hi-res melting     on the LightScanner

John Monahan, David Ruddy, Bella Gorbatcheva, Jeremy Decker, Gwendolyn Yarbrough, WeiHua Liu, Lindsey Cutler, Mikeal Wall, Ranae Martin, Steven Dobrowolski, Jason McKinney, David Teng
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4924.
Published: 01 May 2007
View article titled, Highly sensitive somatic mutation detection in tumor samples by hi-res melting     on the LightScanner