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Journal Articles

Abstract 3245: AXL as a therapeutic target in STK11 mutant NSCLC

Free
Magnus Blø, Austin Rayford, Noëlly Madeleine, Fabian Gärtner, Dana Bohan, Natalie Ruggio, Huiyu Li, Luc Girard, Rolf Brekken, John Minna, Marianne Ånerud, Wendy Maury, Claudia Gorcea-Carson, Gro Gausdal, David R. Micklem, Nigel McCracken
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3245.
https://doi.org/10.1158/1538-7445.AM2023-3245
Published: 04 April 2023
View articletitled, Abstract 3245: AXL as a therapeutic target in STK11 mutant NSCLC
Journal Articles

Abstract 6572: A lung cancer cell line explorer

Free
Ling Cai, Luc Girard, Ralph DeBerardinis, Guanghua Xiao, John Minna, Yang Xie
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6572.
https://doi.org/10.1158/1538-7445.AM2023-6572
Published: 04 April 2023
View articletitled, Abstract 6572: A lung cancer cell line explorer
Journal Articles

Abstract 871: KYNU expression is a prognostic factor in KEAP1/STK11 co-mutated lung adenocarcinoma

Free
Ling Cai, Thomas J. Rogers, Huiyu Li, Jiyeon Kim, Yang Xie, Guanghua Xiao, John Minna, Ralph J. DeBerardinis
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 871.
https://doi.org/10.1158/1538-7445.AM2021-871
Published: 01 July 2021
View articletitled, Abstract 871: KYNU expression is a prognostic factor in KEAP1/STK11 co-mutated lung adenocarcinoma
Journal Articles

Abstract 203: SCLC-CellMiner: An extensive cell line genomic and pharmacology resource identifies a subgroup of small cell lung cancers sensitive to targeted therapies and immunotherapies

Free
Camille Tlemsani, Lorinc Pongor, Fathi Elloumi, Luc Girard, Kenneth Huffman, Nitin Roper, Sudhir Varma, Augustin Luna, Vinodh Rajapakse, Pascaline Boudou-Rouquette, Robin Sebastian, Kurt Kohn, Julia Krushkal, Mirit Aladjem, Beverly Teicher, Paul Meltzer, William Reinhold, John Minna, Anish Thomas, Yves Pommier
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 203.
https://doi.org/10.1158/1538-7445.AM2021-203
Published: 01 July 2021
View articletitled, Abstract 203: SCLC-CellMiner: An extensive cell line genomic and pharmacology resource identifies a subgroup of small cell lung cancers sensitive to targeted therapies and immunotherapies
Journal Articles

Abstract 22: A novel, inflamed small cell lung cancer transcriptional subtype, SCLC-I, defines a subset of patients with distinct immunotherapy vulnerability

Free
Carl M. Gay, C. Allison Stewart, Lixia Diao, Barzin Y. Nabet, Junya Fujimoto, Luisa M. Solis, Wei Lu, Yuanxin Xi, Robert J. Cardnell, Natalie I. Vokes, Kavya Ramkumar, Stephen G. Swisher, Jack A. Roth, Bonnie S. Glisson, David S. Shames, Ignacio I. Wistuba, Jing Wang, John Minna, John V. Heymach, Lauren A. Byers
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 22.
https://doi.org/10.1158/1538-7445.AM2021-22
Published: 01 July 2021
View articletitled, Abstract 22: A novel, inflamed small cell lung cancer transcriptional subtype, SCLC-I, defines a subset of patients with distinct immunotherapy vulnerability
Journal Articles

Abstract 1906: Relationship between neuroendocrine and immune gene expression in small cell lung cancer

Free
Ling Cai, Hongyu Liu, Fang Huang, Junya Fujimoto, Luc Girard, Yang Xie, John Minna, Adi Gazdar
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1906.
https://doi.org/10.1158/1538-7445.AM2021-1906
Published: 01 July 2021
View articletitled, Abstract 1906: Relationship between neuroendocrine and immune gene expression in small cell lung cancer
Journal Articles

Abstract 1016: Inhibition of chemokine-induced myeloid cells potentiates the anti-PD-1 response in KRAS/LKB1 mutant non-small cell lung cancer

Free
Rui Li, Ramin Salehi-Rad, Milica Momcilovic, Stephanie Ong, Raymond Lim, Zi Ling Huang, Linh Tran, Zhe Jing, Manash Paul, Michael Teitell, John Minna, David Shackelford, Krysan Kostyantyn, Bin Liu, Steven Dubinett
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1016.
https://doi.org/10.1158/1538-7445.AM2020-1016
Published: 15 August 2020
View articletitled, Abstract 1016: Inhibition of chemokine-induced myeloid cells potentiates the anti-PD-1 response in KRAS/LKB1 mutant non-small cell lung cancer
Journal Articles

Abstract 557: Novel targeted combination therapies active in KRAS mutant non-small cell lung cancer (NSCLC) identified using patient-derived xenografts (PDX)

Free
Xiaoshan Zhang, Ran Zhang, Huiqin Chen, Li Wang, Chenghui Ren, Shuhong Wu, Min Jin Ha, Jeffrey Morris, Yuanxin Xi, Jing Wang, Don L. Gibbons, John V. Heymach, Funda Meric-Bernstam, John Minna, Stephen G. Swisher, Jack A. Roth, Bingliang Fang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 557.
https://doi.org/10.1158/1538-7445.AM2020-557
Published: 15 August 2020
View articletitled, Abstract 557: Novel targeted combination therapies active in KRAS mutant non-small cell lung cancer (NSCLC) identified using patient-derived xenografts (PDX)
Journal Articles

Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer

Available to Purchase
Shidan Wang, Ruichen Rong, Donghan M. Yang, Junya Fujimoto, Shirley Yan, Ling Cai, Lin Yang, Danni Luo, Carmen Behrens, Edwin R. Parra, Bo Yao, Lin Xu, Tao Wang, Xiaowei Zhan, Ignacio I. Wistuba, John Minna, Yang Xie, Guanghua Xiao
Journal: Cancer Research
Cancer Res (2020) 80 (10): 2056–2066.
https://doi.org/10.1158/0008-5472.CAN-19-1629
Published: 15 May 2020
View articletitled, Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer
Open the PDF for Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1030: Regulation and role of actin dynamics in promoting premalignant cell migration

Free
Manash K. Paul, Arkaprabha Basu, Bharti Bisht, Paul Pagano, Yari Fontebasso, Kostyantyn Krysan, Linh Tran, Mitchel Alioscha-Perez, John Minna, Dino DiCarlo, Hichem Sahli, Shimon Weiss, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1030.
https://doi.org/10.1158/1538-7445.AM2019-1030
Published: 01 July 2019
View articletitled, Abstract 1030: Regulation and role of actin dynamics in promoting premalignant cell migration
Journal Articles

Abstract 2710: Depletion of CXCR2-dependent myeloid-derived suppressor cells (MDSCs) overcomes anti-PD-1 resistance in a murine model of LKB1-deficient non-small cell lung cancer (NSCLC) with high mutational load

Free
Rui Li, Ramin Salehi-Rad, Stephanie Ong, Milica Momcilovic, Bin Liu, Raymond Lim, Linh Tran, Ziling Huang, Zhe Jing, Manash Paul, Kostyantyn Krysan, Stacy Park, John Minna, Michael Teitell, David Shackelford, Steven Dubinett
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2710.
https://doi.org/10.1158/1538-7445.AM2019-2710
Published: 01 July 2019
View articletitled, Abstract 2710: Depletion of CXCR2-dependent myeloid-derived suppressor cells (MDSCs) overcomes anti-PD-1 resistance in a murine model of LKB1-deficient non-small cell lung cancer (NSCLC) with high mutational load
Journal Articles

Abstract 2664: Identification of two small molecules with small cell lung cancer growth inhibition response profiles different from etoposide/topotecan

Free
Allison A. Mootz, Michael Peyton, Paul Yenerall, Kimberley Avila, Kenneth Huffman, Tomohiro Haruki, Mahboubeh Papari-Zareei, Victor Stastny, Luc Girard, Elizabeth McMillan, Michael Roth, John MacMillan, Bruce Posner, Michael White, Gazdar Adi, John Minna
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2664.
https://doi.org/10.1158/1538-7445.AM2018-2664
Published: 01 July 2018
View articletitled, Abstract 2664: Identification of two small molecules with small cell lung cancer growth inhibition response profiles different from etoposide/topotecan
Journal Articles

Abstract 5740: PD-L1 overexpression induced by oncogenic KRAS and BRAF mutations through MAPK pathway activation in non-small cell lung cancer

Free
Yosuke Miura, Noriaki Sunaga, Pinjie Bao, Luc Girard, Yusuke Tsukagoshi, Tomomi Masuda, Norimitsu Kasahara, Reiko Sakurai, Kyoichi Kaira, Takeshi Hisada, John Minna, Masanobu Yamada
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5740.
https://doi.org/10.1158/1538-7445.AM2018-5740
Published: 01 July 2018
View articletitled, Abstract 5740: PD-L1 overexpression induced by oncogenic KRAS and BRAF mutations through MAPK pathway activation in non-small cell lung cancer
Journal Articles

Abstract 1111: The chromatin remodelers RUVBL1 and RUVBL2 are prognostic factors and therapeutic targets in non-small cell lung cancer due to their roles in DNA replication, repair, and radiosensitization

Free
Paul Yenerall, Rahul Kollipara, Amit Das, Pamela Villalobos, Long Shan Li, Brenda Timmons, Luc Girard, Jaime Rodriguez-Canales, Ignacio Wistuba, John Minna, Ralf Kittler
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1111.
https://doi.org/10.1158/1538-7445.AM2017-1111
Published: 01 July 2017
View articletitled, Abstract 1111: The chromatin remodelers RUVBL1 and RUVBL2 are prognostic factors and therapeutic targets in non-small cell lung cancer due to their roles in DNA replication, repair, and radiosensitization
Journal Articles

Abstract 2324: FRA1 contributes to ERK-mediated increased PD-L1 expression in KRAS mutated premalignant human bronchial epithelial cells

Free
Mi-Heon Lee, Jane Yanagawa, Tonya C Walser, Jonathan W. Goldman, Edward B. Garon, Gang Zeng, Sherven Sharma, Boning Gao, John Minna, Steven M. Dubinett, Jay M Lee
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2324.
https://doi.org/10.1158/1538-7445.AM2016-2324
Published: 15 July 2016
View articletitled, Abstract 2324: FRA1 contributes to ERK-mediated increased PD-L1 expression in KRAS mutated premalignant human bronchial epithelial cells
Journal Articles

Abstract LB-071: Kub5-Hera/RPRD1B controls CDK1 regulation and synthetic lethality to PARP1 inhibition

Free
Edward A. Motea, Farjana Fattah, Ling Xiao, Luc Girard, Amy Rommel, Julio Morales, Praveen Patidar, Andrew Porter, John Minna, David Boothman
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-071.
https://doi.org/10.1158/1538-7445.AM2015-LB-071
Published: 01 August 2015
View articletitled, Abstract LB-071: Kub5-Hera/RPRD1B controls CDK1 regulation and synthetic lethality to PARP1 inhibition
Journal Articles

Abstract 2965: Identification of SMARCA4/BRG1 mutation types in NSCLC cell lines and tumors

Free
Wei Zhang, Yibing Yao, Yunyun Zhou, Xiaotu Ma, Jingsheng Yan, Tao Wang, Luc Girard, John Minna, Guanghua Xiao, Yang Xie, Adi Gazdar
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2965.
https://doi.org/10.1158/1538-7445.AM2015-2965
Published: 01 August 2015
View articletitled, Abstract 2965: Identification of SMARCA4/BRG1 mutation types in NSCLC cell lines and tumors
Journal Articles

Abstract 3562: Protein palmitoylation in breast cancer: DHHC5 palmitoyltransferase as a potential therapeutic target

Free
Hui Tian, Xiaoxia Qi, Kenneth Huffman, John Minna, Sandra L. Hofmann
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3562.
https://doi.org/10.1158/1538-7445.AM2015-3562
Published: 01 August 2015
View articletitled, Abstract 3562: Protein palmitoylation in breast cancer: DHHC5 palmitoyltransferase as a potential therapeutic target
Journal Articles

Abstract 4779: RUVBL1 and RUBVL2 are chromatin remodelers that represent prognostic and novel therapeutic targets for a subset of non-small cell lung cancers (NSCLCs)

Free
Paul M. Yenerall, Rahul Kollipara, Ryan Carstens, Kenneth Huffman, Luc Girard, Jaime Rodriguez, Ignacio Wistuba, David Mangelsdorf, John Minna, Ralf Kittler
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4779.
https://doi.org/10.1158/1538-7445.AM2015-4779
Published: 01 August 2015
View articletitled, Abstract 4779: RUVBL1 and RUBVL2 are chromatin remodelers that represent prognostic and novel therapeutic targets for a subset of non-small cell lung cancers (NSCLCs)
Journal Articles

Abstract PR11: Dissecting signaling transduction network to infer master regulators of non small cell lung cancer

Free
Mukesh Bansal, Jr., Michael Peyton, Manjunath Kustagi, Luc Girard, Klarisa Rikova, Michael Comb, Michael White, John Minna, Andrea Califano
Journal: Cancer Research
Cancer Res (2012) 72 (13_Supplement): PR11.
https://doi.org/10.1158/1538-7445.CSB12-PR11
Published: 06 November 2014
View articletitled, Abstract PR11: Dissecting signaling transduction network to infer master regulators of non small cell lung cancer